| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Barbara Bottalico, Radovan Pilka, Irene Larsson, Bertil Casslen, Karel Marsal, Stefan R Hansso. Plasma membrane and vesicular monoamine transporters in normal endometrium and early pregnancy decidua. Molecular human reproduction. vol 9. issue 7. 2016-04-23. PMID:12802045. |
extracellular monoamine levels are regulated primarily through re-uptake by specific membrane-bound transporter proteins dopamine transporter (dat), norepinephrine transporter (net) and serotonin transporter (sert). |
2016-04-23 |
2023-08-12 |
Not clear |
| Yang Li, Peter S Hasenhuetl, Klaus Schicker, Harald H Sitte, Michael Freissmuth, Walter Sandtne. Dual Action of Zn2+ on the Transport Cycle of the Dopamine Transporter. The Journal of biological chemistry. vol 290. issue 52. 2016-04-22. PMID:26504078. |
the dopamine transporter carries an endogenous binding site for zn(2+), but the nature of the zn(2+)-dependent modulation has remained elusive: both, inhibition and stimulation of dat have been reported. |
2016-04-22 |
2023-08-13 |
Not clear |
| Fabio Sambataro, Jamie E Podell, Vishnu P Murty, Saumitra Das, Bhaskar Kolachana, Terry E Goldberg, Daniel R Weinberger, Venkata S Matta. A variable number of tandem repeats in the 3'-untranslated region of the dopamine transporter modulates striatal function during working memory updating across the adult age span. The European journal of neuroscience. vol 42. issue 3. 2016-04-20. PMID:25997640. |
the dopamine transporter (dat) regulates striatal dopamine signaling via synaptic reuptake. |
2016-04-20 |
2023-08-13 |
Not clear |
| Fabio Sambataro, Jamie E Podell, Vishnu P Murty, Saumitra Das, Bhaskar Kolachana, Terry E Goldberg, Daniel R Weinberger, Venkata S Matta. A variable number of tandem repeats in the 3'-untranslated region of the dopamine transporter modulates striatal function during working memory updating across the adult age span. The European journal of neuroscience. vol 42. issue 3. 2016-04-20. PMID:25997640. |
a variable number of tandem repeats in the 3'-untranslated region of slc6a3 (dat1-3'-utr-vntr) is associated with dat expression, such that 9-repeat allele carriers tend to express lower levels (associated with higher extracellular dopamine concentrations) than 10-repeat homozygotes. |
2016-04-20 |
2023-08-13 |
Not clear |
| Susana Mingote, Nao Chuhma, Sheila V Kusnoor, Bianca Field, Ariel Y Deutch, Stephen Raypor. Functional Connectome Analysis of Dopamine Neuron Glutamatergic Connections in Forebrain Regions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 49. 2016-04-20. PMID:26658874. |
to visualize dopamine neuron forebrain projections and to enable photostimulation of their axons independent of transmitter status, we virally transfected vta neurons with channelrhodopsin-2 fused to enhanced yellow fluorescent protein (chr2-eyfp) and used dat(irescre) mice to restrict expression to dopamine neurons. |
2016-04-20 |
2023-08-13 |
mouse |
| Brittany Butler, Kaustuv Saha, Tanu Rana, Jonas P Becker, Danielle Sambo, Paran Davari, J Shawn Goodwin, Habibeh Khoshboue. Dopamine Transporter Activity Is Modulated by α-Synuclein. The Journal of biological chemistry. vol 290. issue 49. 2016-04-19. PMID:26442590. |
the duration and strength of the dopaminergic signal are regulated by the dopamine transporter (dat). |
2016-04-19 |
2023-08-13 |
Not clear |
| Brittany Butler, Kaustuv Saha, Tanu Rana, Jonas P Becker, Danielle Sambo, Paran Davari, J Shawn Goodwin, Habibeh Khoshboue. Dopamine Transporter Activity Is Modulated by α-Synuclein. The Journal of biological chemistry. vol 290. issue 49. 2016-04-19. PMID:26442590. |
little is known about the regulatory mechanisms of the interaction between dat and α-synuclein, the cellular location of this interaction, and the functional consequences of this interaction on the basal, amphetamine-induced dat-mediated dopamine efflux, and membrane microdomain distribution of the transporter. |
2016-04-19 |
2023-08-13 |
Not clear |
| Brittany Butler, Kaustuv Saha, Tanu Rana, Jonas P Becker, Danielle Sambo, Paran Davari, J Shawn Goodwin, Habibeh Khoshboue. Dopamine Transporter Activity Is Modulated by α-Synuclein. The Journal of biological chemistry. vol 290. issue 49. 2016-04-19. PMID:26442590. |
additionally, we found dat-induced membrane depolarization enhances plasma membrane localization of α-synuclein, which in turn increases dopamine efflux and enhances dat localization in cholesterol-rich membrane microdomains. |
2016-04-19 |
2023-08-13 |
Not clear |
| Siim Kukk, Vladimir Stepanov, Jaak Jär. Thermal Stability of Dopamine Transporters. The Journal of membrane biology. vol 248. issue 4. 2016-04-18. PMID:25812533. |
the thermal stabilities of the rat and mouse dopamine transporter (dat) proteins were studied within the temperature range of 0-37°c. |
2016-04-18 |
2023-08-13 |
mouse |
| Sandy Stayte, Peggy Rentsch, Kong M Li, Bryce Visse. Activin A protects midbrain neurons in the 6-hydroxydopamine mouse model of Parkinson's disease. PloS one. vol 10. issue 4. 2016-04-12. PMID:25902062. |
however, we found no corresponding protection of striatal da or dopamine transporter (dat) expression levels in animals receiving activin a compared to vehicle controls. |
2016-04-12 |
2023-08-13 |
mouse |
| J Hong, S Sha, L Zhou, C Wang, J Yin, L Che. Sigma-1 receptor deficiency reduces MPTP-induced parkinsonism and death of dopaminergic neurons. Cell death & disease. vol 6. 2016-04-12. PMID:26203861. |
the pharmacological or genetic inactivation of σ1r suppressed the expression of dopamine transporter (dat) in substantia nigra, which was corrected by nmda. |
2016-04-12 |
2023-08-13 |
mouse |
| Ashley L Green, Muhammad M Hossain, Siew C Tee, Helmut Zarbl, Grace L Guo, Jason R Richardso. Epigenetic Regulation of Dopamine Transporter mRNA Expression in Human Neuroblastoma Cells. Neurochemical research. vol 40. issue 7. 2016-04-11. PMID:25963949. |
the dopamine transporter (dat) is a key regulator of dopaminergic neurotransmission. |
2016-04-11 |
2023-08-13 |
human |
| Beata Gryzło, Paula Zaręba, Katarzyna Malawska, Anna Jakubowska, Katarzyna Kuli. Progress in the Search for New Dopamine Transporter Inhibitors. Current medicinal chemistry. vol 22. issue 28. 2016-04-08. PMID:26264922. |
in the present review, we provide a comprehensive summary of recent pharmacological studies on dopamine transporter (dat) inhibitors, which are potential treatments for neurodegenerative and psychiatric disorders. |
2016-04-08 |
2023-08-13 |
Not clear |
| Chunhai Chen, Qinglong Ma, Xiaowei Chen, Min Zhong, Ping Deng, Gang Zhu, Yanwen Zhang, Lei Zhang, Zhiqi Yang, Kuan Zhang, Lu Guo, Liting Wang, Zhengping Yu, Zhou Zho. Thyroid Hormone-Otx2 Signaling Is Required for Embryonic Ventral Midbrain Neural Stem Cells Differentiated into Dopamine Neurons. Stem cells and development. vol 24. issue 15. 2016-04-06. PMID:25867707. |
we find that thyroid hormone deficiency during development reduces the midbrain da neuron number, downregulates the expression of tyrosine hydroxylase (th) and the dopamine transporter (dat), and impairs the da neuron-dependent motor behavior. |
2016-04-06 |
2023-08-13 |
Not clear |
| April S Masarik, Rand D Conger, M Brent Donnellan, Michael C Stallings, Monica J Martin, Thomas J Schofield, Tricia K Neppl, Laura V Scaramella, Andrew Smolen, Keith F Widama. For better and for worse: genes and parenting interact to predict future behavior in romantic relationships. Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43). vol 28. issue 3. 2016-04-04. PMID:24821524. |
we created an index for hypothesized genetic plasticity by summing g2's allelic variation for polymorphisms in 5 genes (serotonin transporter gene [linked polymorphism], 5-htt; ankyrin repeat and kinase domain containing 1 gene/dopamine receptor d2 gene, ankk1/drd2; dopamine receptor d4 gene, drd4; dopamine active transporter gene, dat; and catechol-o-methyltransferase gene, comt). |
2016-04-04 |
2023-08-13 |
human |
| A Rieckmann, S N Gomperts, K A Johnson, J H Growdon, K R A Van Dij. Putamen-midbrain functional connectivity is related to striatal dopamine transporter availability in patients with Lewy body diseases. NeuroImage. Clinical. vol 8. 2016-04-04. PMID:26137443. |
we assessed functional connectivity of the putamen during resting state fmri and dopamine transporter (dat) availability in the striatum using 11c-altropane pet in twenty patients. |
2016-04-04 |
2023-08-13 |
Not clear |
| Paul Cumming, Simone Maschauer, Patrick J Riss, Eva Grill, Monika Pischetsrieder, Torsten Kuwert, Olaf Prant. Perturbed Development of Striatal Dopamine Transporters in Fatty Versus Lean Zucker Rats: a Follow-up Small Animal PET Study. Molecular imaging and biology. vol 17. issue 4. 2016-04-01. PMID:25537092. |
therefore, we used positron emission tomography (pet) with the dopamine transporter (dat) ligand n-(3-[(18)f]fluoropropyl)-2-β-carbomethoxy-3-β-(4'-methylphenyl) tropane ([(18)f]fp-cmt) to test the hypothesis that dat availability is attenuated in adult fatty zucker (fz) rats versus lean littermates (lz). |
2016-04-01 |
2023-08-13 |
rat |
| S-J Hong, D Zhang, L-H Zhang, P Yang, J Wan, Y Yu, T-H Wang, Z-T Feng, L-H Li, D T W Ye. Expression of dopamine transporter in the different cerebral regions of methamphetamine-dependent rats. Human & experimental toxicology. vol 34. issue 7. 2016-03-30. PMID:25504685. |
to observe the expression of the dopamine transporter (dat) in six cerebral regions of a methamphetamine (ma)-dependent rat, which were frontal cortex, nucleus accumbens septi, striatum, hippocampus, substantia nigra and ventral tegmental area. |
2016-03-30 |
2023-08-13 |
rat |
| T Krzymowski, S Stefanczyk-Krzymowsk. New facts and the concept of physiological regulation of the dopaminergic system function and its disorders. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 66. issue 3. 2016-03-30. PMID:26084215. |
we are convinced that under physiological conditions da - which is continuously retrograde transferred in the cavernous sinus from venous brain effluent to arterial blood supplying the brain and carried by the arterial blood to endothelial cells and perivascular astrocytes of striatal dargic cell groups - can inhibit dopamine transporter (dat) expression by a down-regulation mechanism. |
2016-03-30 |
2023-08-13 |
Not clear |
| Kusumika Saha, John S Partilla, Kurt R Lehner, Amir Seddik, Thomas Stockner, Marion Holy, Walter Sandtner, Gerhard F Ecker, Harald H Sitte, Michael H Bauman. 'Second-generation' mephedrone analogs, 4-MEC and 4-MePPP, differentially affect monoamine transporter function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 6. 2016-03-29. PMID:25502630. |
here we characterized the interactions of 4-mec and 4-meppp with transporters for 5-ht (sert) and dopamine (dat) using molecular, cellular, and whole-animal methods. |
2016-03-29 |
2023-08-13 |
rat |