| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L-L Bu, F-T Liu, C-F Jiang, S-S Guo, H Yu, C-T Zuo, P Wu, J Wan. Patterns of dopamine transporter imaging in subtypes of multiple system atrophy. Acta neurologica Scandinavica. vol 138. issue 2. 2018-10-02. PMID:29573392. |
to investigate the differences in the pattern of striatal (caudate and putamen) dopamine transporter (dat) loss in a multiple system atrophy (msa) cohort, based on the clinical variants parkinsonian subtype (msa-p) and cerebellar subtype (msa-c) via (11)c-n-2-carbomethoxy-3-(4-fluorophenyl)-tropane ( |
2018-10-02 |
2023-08-13 |
Not clear |
| E Riley, V Maymi, S Pawlyszyn, L Yu, I V Zhdanov. Prenatal cocaine exposure disrupts the dopaminergic system and its postnatal responses to cocaine. Genes, brain, and behavior. vol 17. issue 4. 2018-10-01. PMID:29105298. |
organism-wide, pce results in a 1.7-fold reduction in the expression of the dopamine transporter (dat), at baseline. |
2018-10-01 |
2023-08-13 |
zebrafish |
| A Adinolfi, C Carbone, D Leo, R R Gainetdinov, G Laviola, W Adrian. Novelty-related behavior of young and adult dopamine transporter knockout rats: Implication for cognitive and emotional phenotypic patterns. Genes, brain, and behavior. vol 17. issue 4. 2018-10-01. PMID:29406596. |
a new animal model of this disorder was developed in rats with genetic deletion of the dopamine transporter (dat) gene (dopamine transporter knockout rats; dat-ko rats). |
2018-10-01 |
2023-08-13 |
human |
| Francesca Longhena, Gaia Faustini, Cristina Missale, Marina Pizzi, Arianna Bellucc. Dopamine Transporter/α-Synuclein Complexes Are Altered in the Post Mortem Caudate Putamen of Parkinson's Disease: An In Situ Proximity Ligation Assay Study. International journal of molecular sciences. vol 19. issue 6. 2018-10-01. PMID:29848975. |
by using the in situ proximity ligation assay (pla), which allows for the visualization of protein-protein interactions in tissues to detect dopamine transporter (dat)/α-synuclein complexes, we previously described that these are markedly redistributed in the striatum of human α-synuclein transgenic mice at the phenotypic stage, showing dopamine (da) release impairment without a dat drop and motor symptoms. |
2018-10-01 |
2023-08-13 |
mouse |
| Michael Freissmuth, Thomas Stockner, Sonja Suci. SLC6 Transporter Folding Diseases and Pharmacochaperoning. Handbook of experimental pharmacology. vol 245. 2018-09-20. PMID:29086036. |
prominent examples include mutations in the transporters for dopamine (dat, slc6a3), for creatine (ct1, slc6a8), and for glycine (glyt2, slc6a5), which result in infantile dystonia, mental retardation, and hyperekplexia, respectively. |
2018-09-20 |
2023-08-13 |
human |
| Sunao Mizumura, Kazuhiro Nishikawa, Akihiro Murata, Kosei Yoshimura, Nobutomo Ishii, Tadashi Kokubo, Miyako Morooka, Akiko Kajiyama, Atsuro Terahar. Improvement in the measurement error of the specific binding ratio in dopamine transporter SPECT imaging due to exclusion of the cerebrospinal fluid fraction using the threshold of voxel RI count. Annals of nuclear medicine. vol 32. issue 4. 2018-09-20. PMID:29546633. |
in japan, the southampton method for dopamine transporter (dat) spect is widely used to quantitatively evaluate striatal radioactivity. |
2018-09-20 |
2023-08-13 |
Not clear |
| Martina Kristofova, Yogesh D Aher, Marija Ilic, Bojana Radoman, Predrag Kalaba, Vladimir Dragacevic, Nilima Y Aher, Johann Leban, Volker Korz, Lisa Zanon, Winfried Neuhaus, Marcus Wieder, Thierry Langer, Ernst Urban, Harald H Sitte, Harald Hoeger, Gert Lubec, Jana Aradsk. A daily single dose of a novel modafinil analogue CE-123 improves memory acquisition and memory retrieval. Behavioural brain research. vol 343. 2018-09-18. PMID:29410048. |
since dat blockers can be considered as indirect dopamine receptor agonists, western blotting was used to quantify protein levels of dopamine receptors d1r, d2r and d5r and dat in the synaptosomal fraction of hippocampal subregions ca1, ca3 and dentate gyrus (dg). |
2018-09-18 |
2023-08-13 |
human |
| Yu Iwabuchi, Tadaki Nakahara, Masashi Kameyama, Yoshitake Yamada, Masahiro Hashimoto, Yuji Ogata, Yohji Matsusaka, Mari Katagiri, Kazunari Itoh, Takashi Osada, Daisuke Ito, Hajime Tabuchi, Masahiro Jinzak. Quantitative evaluation of the tracer distribution in dopamine transporter SPECT for objective interpretation. Annals of nuclear medicine. vol 32. issue 5. 2018-09-18. PMID:29654576. |
quantification of the tracer distribution would add objectivity to the visual assessments of dopamine transporter (dat) single photon emission computed tomography (spect) data. |
2018-09-18 |
2023-08-13 |
Not clear |
| Angelo Fabio Gigante, Artor Niccoli Asabella, Giovanni Iliceto, Tommaso Martino, Cristina Ferrari, Giovanni Defazio, Giuseppe Rubin. Chronic coffee consumption and striatal DAT-SPECT findings in Parkinson's disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 39. issue 3. 2018-08-30. PMID:29362953. |
this study aimed to see whether coffee habit could be associated with change in striatal dopamine active transporter (dat)-single photon emission computed tomography (spect) imaging in pd. |
2018-08-30 |
2023-08-13 |
Not clear |
| Tanawan Leeboonngam, Ratchadaporn Pramong, Kwankanit Sae-Ung, Piyarat Govitrapong, Pansiri Phansuwan-Pujit. Neuroprotective effects of melatonin on amphetamine-induced dopaminergic fiber degeneration in the hippocampus of postnatal rats. Journal of pineal research. vol 64. issue 3. 2018-08-28. PMID:29149481. |
melatonin attenuated the amph-induced reduction in dopamine transporter (dat) protein expression in the hippocampus and the reduction in mrna expression in the ventral tegmental area (vta). |
2018-08-28 |
2023-08-13 |
rat |
| Tomoko Maekawa, Noriko Sato, Miho Ota, Atsuhiko Sugiyama, Daichi Sone, Mikako Enokizono, Yukio Kimura, Youhei Mukai, Miho Murata, Harumasa Takano, Etsuko Imabayashi, Hiroshi Matsuda, Akira Kunimatsu, Osamu Ab. Correlations between dopamine transporter density measured by Japanese journal of radiology. vol 35. issue 12. 2018-08-22. PMID:29063467. |
the relationship between dopamine transporter (dat) density and gray matter volume has been unclear. |
2018-08-22 |
2023-08-13 |
Not clear |
| Adelaide Greco, Antonella Zannetti, Sabina Pappatà, Sandra Albanese, Anna R Coda, Monica Ragucci, Anna Nardelli, Arturo Brunetti, Alberto Cuocolo, Marco Salvator. Measurement of [123I]FP-CIT binding to the dopamine transporter (DAT) in healthy mouse striatum using dedicated small animal SPECT imaging: feasibility, optimization and validation. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... vol 62. issue 1. 2018-08-17. PMID:26329495. |
measurement of [123i]fp-cit binding to the dopamine transporter (dat) in healthy mouse striatum using dedicated small animal spect imaging: feasibility, optimization and validation. |
2018-08-17 |
2023-08-13 |
mouse |
| Adelaide Greco, Antonella Zannetti, Sabina Pappatà, Sandra Albanese, Anna R Coda, Monica Ragucci, Anna Nardelli, Arturo Brunetti, Alberto Cuocolo, Marco Salvator. Measurement of [123I]FP-CIT binding to the dopamine transporter (DAT) in healthy mouse striatum using dedicated small animal SPECT imaging: feasibility, optimization and validation. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... vol 62. issue 1. 2018-08-17. PMID:26329495. |
in-vivo imaging of dopamine transporter (dat), a reliable marker of degeneration of nigrostriatal dopaminergic innervation, has gained increasing interest in preclinical neurodegenerative research for studying disease mechanisms and testing new therapeutic strategies. |
2018-08-17 |
2023-08-13 |
mouse |
| Giulia Costa, Micaela Morelli, Nicola Simol. Progression and Persistence of Neurotoxicity Induced by MDMA in Dopaminergic Regions of the Mouse Brain and Association with Noradrenergic, GABAergic, and Serotonergic Damage. Neurotoxicity research. vol 32. issue 4. 2018-08-07. PMID:28597409. |
in order to characterize how the number of administrations influenced the severity of mdma-induced dopaminergic damage and to describe the localization and persistence of this damage, we evaluated the changes in tyrosine hydroxylase (th) and dopamine transporter (dat) in different regions of the mouse brain. |
2018-08-07 |
2023-08-13 |
mouse |
| Giuseppe Giannotti, Isabella Canazza, Lucia Caffino, Sabrine Bilel, Andrea Ossato, Fabio Fumagalli, Matteo Mart. The Cathinones MDPV and α-PVP Elicit Different Behavioral and Molecular Effects Following Acute Exposure. Neurotoxicity research. vol 32. issue 4. 2018-08-07. PMID:28646469. |
in particular, mdpv showed a greater psychomotor effect than α-pvp in line with its higher potency in blocking the dopamine transporter (dat). |
2018-08-07 |
2023-08-13 |
Not clear |
| Kyoungjune Pak, Keunyoung Kim, Myung Jun Lee, Jae Meen Lee, Bum Soo Kim, Seong-Jang Kim, In Joo Ki. Correlation between the availability of dopamine transporter and olfactory function in healthy subjects. European radiology. vol 28. issue 4. 2018-08-02. PMID:29164380. |
in this study, we aimed to explore the association of olfactory function with the availabilities of striatal dopamine transporter (dat) in healthy subjects. |
2018-08-02 |
2023-08-13 |
human |
| Esfandiar Azadmarzabadi, Arvin Haghighatfard, Alireza Mohammad. Low resilience to stress is associated with candidate gene expression alterations in the dopaminergic signalling pathway. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 18. issue 3. 2018-08-01. PMID:29423959. |
here, we aimed to describe the association between comprehensive psychological characteristics and messenger rna levels of dopamine receptor d1 (drd1), dopamine receptor d2 (drd2), dopamine receptor d3 (drd3), dopamine receptor d4 (drd4), dopamine receptor d5 (drd5), comt, dopamine beta-hydroxylase (dbh), tyrosine hydroxylase (th), monoamine oxidase a (maom), dopa decarboxylase (ddc), dopamine transporter (dat), serotonin transporter (5-htt), brain-derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf) genes based on peripheral blood samples from 400 subjects who react differently to major life event stressors. |
2018-08-01 |
2023-08-13 |
human |
| Youngduk Seo, Kyoungjune Pak, Hyun Yeol Nam, Ju Won Seok, Myung Jun Lee, Eun Joo Kim, Jae Meen Lee, Seong Jang Kim, In Joo Ki. Effect of rs3910105 in the Synuclein Gene on Dopamine Transporter Availability in Healthy Subjects. Yonsei medical journal. vol 59. issue 6. 2018-07-31. PMID:29978616. |
the present study investigated associations between dopamine transporter (dat) availability and α-synuclein levels in cerebrospinal fluid, as well as synuclein gene (snca) transcripts, and the effect of single nucleotide polymorphism of snca on dat availability in healthy subjects. |
2018-07-31 |
2023-08-13 |
human |
| Yi Yu, Huiyong Sun, Keith Gilmore, Tingjun Hou, Suidong Wang, Youyong L. Aggregated Single-Walled Carbon Nanotubes Absorb and Deform Dopamine-Related Proteins Based on Molecular Dynamics Simulations. ACS applied materials & interfaces. vol 9. issue 38. 2018-07-30. PMID:28859474. |
by using all-atom molecular dynamics simulations, we investigate the effects of single and aggregated swcnts (single-(10,10)cnt, aggregated-7-(10,10)cnts, and single-(35,35)cnt with the same diameter as that of the aggregated one) on the activity of dopamine-related proteins [tyrosine hydroxylase (tyroh) and dopamine transporter (dat), which are related to the synthesis and transport of dopamine, respectively]. |
2018-07-30 |
2023-08-13 |
Not clear |
| Yi Yu, Huiyong Sun, Keith Gilmore, Tingjun Hou, Suidong Wang, Youyong L. Aggregated Single-Walled Carbon Nanotubes Absorb and Deform Dopamine-Related Proteins Based on Molecular Dynamics Simulations. ACS applied materials & interfaces. vol 9. issue 38. 2018-07-30. PMID:28859474. |
for dat, our results suggest that the aggregated-7-(10,10)cnts allow dat to maintain an outward-facing conformation and hence are favorable to the reuptake of dopamine. |
2018-07-30 |
2023-08-13 |
Not clear |