| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Brendan J Tunstall, Chelsea P Ho, Jianjing Cao, Janaína C M Vendruscolo, Brooke E Schmeichel, Rachel D Slack, Gianluigi Tanda, Alexandra J Gadiano, Rana Rais, Barbara S Slusher, George F Koob, Amy H Newman, Leandro F Vendruscol. Atypical dopamine transporter inhibitors attenuate compulsive-like methamphetamine self-administration in rats. Neuropharmacology. vol 131. 2018-11-13. PMID:29217282. |
similar to meth, the wake-promoting drug (r)-modafinil (r-mod) binds to the dopamine transporter (dat). |
2018-11-13 |
2023-08-13 |
rat |
| Ross McFarland, Zi Teng Wang, Yan Jouroukhin, Ye Li, Olga Mychko, Isabelle Coppens, Jianchun Xiao, Lorraine Jones-Brando, Robert H Yolken, L David Sibley, Mikhail V Pletniko. AAH2 gene is not required for dopamine-dependent neurochemical and behavioral abnormalities produced by Toxoplasma infection in mouse. Behavioural brain research. vol 347. 2018-11-13. PMID:29555339. |
we found that chronic t. gondii infection of balb/c mice leads to blunted response to amphetamine or cocaine and decreased expression of dopamine transporter (dat) and vesicular monoamine transporter 2 (vmat2). |
2018-11-13 |
2023-08-13 |
mouse |
| Felix P Mayer, Nadine V Burchardt, Ann M Decker, John S Partilla, Yang Li, Gavin McLaughlin, Pierce V Kavanagh, Walter Sandtner, Bruce E Blough, Simon D Brandt, Michael H Baumann, Harald H Sitt. Fluorinated phenmetrazine "legal highs" act as substrates for high-affinity monoamine transporters of the SLC6 family. Neuropharmacology. vol 134. issue Pt A. 2018-11-07. PMID:28988906. |
here we tested 3-fpm and its positional isomers, 2-fpm and 4-fpm, for their abilities to interact with plasma membrane monoamine transporters for dopamine (dat), norepinephrine (net) and serotonin (sert). |
2018-11-07 |
2023-08-13 |
Not clear |
| Katarzyna Kamińska, Karolina Noworyta-Sokołowska, Anna Górska, Joanna Rzemieniec, Agnieszka Wnuk, Adam Wojtas, Grzegorz Kreiner, Małgorzata Kajta, Krystyna Gołembiowsk. The Effects of Exposure to Mephedrone During Adolescence on Brain Neurotransmission and Neurotoxicity in Adult Rats. Neurotoxicity research. vol 34. issue 3. 2018-11-06. PMID:29713996. |
mephedrone by its interaction with transporters for dopamine (dat) and serotonin (sert) stimulates their release to the synaptic cleft. |
2018-11-06 |
2023-08-13 |
mouse |
| Kyoungjune Pak, Hyun-Yeol Nam, Seunghyeon Shin, Keunyoung Kim, Myung Jun Lee, Eun-Joo Kim, Jae Meen Lee, Seong-Jang Kim, In Joo Ki. Effects of rs591323 on serotonin transporter availability in healthy male subjects. Annals of nuclear medicine. vol 32. issue 7. 2018-11-06. PMID:29774458. |
we aimed to investigate the association between genetic factors of snps dopamine transporter (dat) and serotonin transporter (sert) availabilities in healthy controls. |
2018-11-06 |
2023-08-13 |
human |
| Danielle O Sambo, Min Lin, Anthony Owens, Joseph J Lebowitz, Ben Richardson, Darin A Jagnarine, Madhur Shetty, Meghan Rodriquez, Taiwo Alonge, Mishaal Ali, Jonathan Katz, Long Yan, Marcelo Febo, L Keith Henry, Adriaan W Bruijnzeel, Lynette Daws, Habibeh Khoshboue. The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission. Nature communications. vol 8. issue 1. 2018-11-05. PMID:29263318. |
dopamine neurotransmission is highly dysregulated by the psychostimulant methamphetamine, a substrate for the dopamine transporter (dat). |
2018-11-05 |
2023-08-13 |
Not clear |
| Danielle O Sambo, Min Lin, Anthony Owens, Joseph J Lebowitz, Ben Richardson, Darin A Jagnarine, Madhur Shetty, Meghan Rodriquez, Taiwo Alonge, Mishaal Ali, Jonathan Katz, Long Yan, Marcelo Febo, L Keith Henry, Adriaan W Bruijnzeel, Lynette Daws, Habibeh Khoshboue. The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission. Nature communications. vol 8. issue 1. 2018-11-05. PMID:29263318. |
through interactions with dat, methamphetamine increases extracellular dopamine levels in the brain, leading to its rewarding and addictive properties. |
2018-11-05 |
2023-08-13 |
Not clear |
| Marc Morissette, Nicolas Morin, Claude Rouillard, Thérèse Di Paol. Membrane cholesterol removal and replenishment affect rat and monkey brain monoamine transporters. Neuropharmacology. vol 133. 2018-11-05. PMID:29407218. |
the dopamine transporter (dat) is abundantly expressed in the striatum where it removes extracellular dopamine into the cytosol of presynaptic nerve terminals. |
2018-11-05 |
2023-08-13 |
rat |
| Koh Tadokoro, Yasuyuki Ohta, Kota Sato, Takahiro Maeki, Ryo Sasaki, Yoshiaki Takahashi, Jingwei Shang, Mami Takemoto, Nozomi Hishikawa, Toru Yamashita, Chang Kweng Lim, Shigeru Tajima, Koji Ab. A Japanese Encephalitis Patient Presenting with Parkinsonism with Corresponding Laterality of Magnetic Resonance and Dopamine Transporter Imaging Findings. Internal medicine (Tokyo, Japan). vol 57. issue 15. 2018-11-05. PMID:29526949. |
dopamine transporter (dat) imaging using |
2018-11-05 |
2023-08-13 |
Not clear |
| Vincent Chin-Hung Chen, Chun-Ching Chiu, Li-Jeng Chen, Tsai-Ching Hsu, Bor-Show Tzan. Effects of taurine on striatal dopamine transporter expression and dopamine uptake in SHR rats. Behavioural brain research. vol 348. 2018-11-05. PMID:29694913. |
this study investigates the effect of taurine on the shr striatum by detecting the spontaneous alternation, da transporter (dat) level, dopamine uptake and brain-derived neurotrophic factor (bdnf) expression. |
2018-11-05 |
2023-08-13 |
rat |
| Vincent Chin-Hung Chen, Chun-Ching Chiu, Li-Jeng Chen, Tsai-Ching Hsu, Bor-Show Tzan. Effects of taurine on striatal dopamine transporter expression and dopamine uptake in SHR rats. Behavioural brain research. vol 348. 2018-11-05. PMID:29694913. |
these findings indicate that different dosages of taurine have opposite effects on striatal dat expression and dopamine uptake, suggesting high-dose taurine as a possible candidate for adhd treatment. |
2018-11-05 |
2023-08-13 |
rat |
| Sathya Challasivakanaka, Juan Zhen, Margaret E Smith, Maarten E A Reith, James D Foster, Roxanne A Vaugha. Dopamine transporter phosphorylation site threonine 53 is stimulated by amphetamines and regulates dopamine transport, efflux, and cocaine analog binding. The Journal of biological chemistry. vol 292. issue 46. 2018-10-29. PMID:28939767. |
the dopamine transporter (dat) controls the spatial and temporal dynamics of dopamine neurotransmission through reuptake of extracellular transmitter and is a target for addictive compounds such as cocaine, amphetamine (amph), and methamphetamine (meth). |
2018-10-29 |
2023-08-13 |
rat |
| Katherine Coulombe, Olivier Kerdiles, Cyntia Tremblay, Vincent Emond, Manon Lebel, Anne-Sophie Boulianne, Mélanie Plourde, Francesca Cicchetti, Frédéric Calo. Impact of DHA intake in a mouse model of synucleinopathy. Experimental neurology. vol 301. issue Pt A. 2018-10-24. PMID:29229294. |
thy1-αsyn mice displayed impaired motor skills, lower dopaminergic neuronal counts within the substantia nigra (-13%) in parallel to decreased levels of the striatal dopamine transporter (dat) (-24%), as well as reduced neun (-41%) and synaptic proteins psd-95 (-51%), synaptophysin (-80%) and vesicular acetylcholine transporter (vchat) (-40%) in the cerebral cortex compared to c57/bl6 mice. |
2018-10-24 |
2023-08-13 |
mouse |
| Luísa Becker Bertotto, Jaben Richards, Jay Gan, David Christopher Volz, Daniel Schlen. Effects of bifenthrin exposure on the estrogenic and dopaminergic pathways in zebrafish embryos and juveniles. Environmental toxicology and chemistry. vol 37. issue 1. 2018-10-22. PMID:28815728. |
quantitative reverse transcriptase polymerase chain reaction was used to investigate transcripts of tyrosine hydroxylase (th), dopamine receptor 1 (dr1) and 2a (dr2a), dopamine active transporter (dat), estrogen receptor α (erα), erβ1, erβ2, luteinizing hormone β (lhβ), follicle-stimulating hormone β (fshβ), vitellogenin (vtg), cytochrome p450 cyp19a1a, and cyp19a1b. |
2018-10-22 |
2023-08-13 |
zebrafish |
| Naveed Malek, Ravi Jampana, Donald G Grosse. Rare case of atypical parkinsonism: why family history is important. Scottish medical journal. vol 62. issue 4. 2018-10-22. PMID:29192564. |
magnetic resonance imaging scan of the brain was normal and a dat spect scan showed reduced dopamine uptake in the basal ganglia. |
2018-10-22 |
2023-08-13 |
Not clear |
| Anna Rieckmann, Keith A Johnson, Reisa A Sperling, Randy L Buckner, Trey Hedde. Dedifferentiation of caudate functional connectivity and striatal dopamine transporter density predict memory change in normal aging. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 40. 2018-10-16. PMID:30224467. |
here, we used fmri to measure functional connectivity of caudate subfields with large-scale association networks and positron emission tomography to measure striatal dopamine transporter (dat) density in 51 older adults (age 65-86 years) who received annual cognitive testing for up to 7 years (mean = 5.59, range 2-7 years). |
2018-10-16 |
2023-08-13 |
Not clear |
| Asghar M Razavi, George Khelashvili, Harel Weinstei. A Markov State-based Quantitative Kinetic Model of Sodium Release from the Dopamine Transporter. Scientific reports. vol 7. 2018-10-15. PMID:28059145. |
the dopamine transporter (dat) belongs to the neurotransmitter:sodium symporter (nss) family of membrane proteins that are responsible for reuptake of neurotransmitters from the synaptic cleft to terminate a neuronal signal and enable subsequent neurotransmitter release from the presynaptic neuron. |
2018-10-15 |
2023-08-13 |
human |
| Yohei Mukai, Yuji Takahashi, Miho Murat. [Questionnaire survey of Scans Without Evidence of Dopaminergic Deficit (SWEDD) in Japan]. Rinsho shinkeigaku = Clinical neurology. vol 58. issue 9. 2018-10-11. PMID:30175806. |
sixty-three neurologists stated that they performed dopamine transporter single photon emission computed tomography (dat spect) on almost all patients with parkinson's disease. |
2018-10-11 |
2023-08-13 |
Not clear |
| Yuichi Wakabayashi, Ryuichi Takahashi, Tomonori Kanda, Feibi Zeng, Munenobu Nogami, Kazunari Ishii, Takamichi Murakam. Semi-quantitative dopamine transporter standardized uptake value in comparison with conventional specific binding ratio in [123I] FP-CIT single-photon emission computed tomography (DaTscan). Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 39. issue 8. 2018-10-09. PMID:29748936. |
we developed a new analytical method to quantify the dopamine transporter (dat) radiation dose in the striatum on [ |
2018-10-09 |
2023-08-13 |
Not clear |
| Ajenthan Surendranathan, John Tiernan O'Brie. Clinical imaging in dementia with Lewy bodies. Evidence-based mental health. vol 21. issue 2. 2018-10-03. PMID:29602778. |
dopamine transporter (dat) imaging remains the best modality for differentiation from dementia of alzheimer's type with high sensitivity and specificity reported based on pathological diagnoses. |
2018-10-03 |
2023-08-13 |
Not clear |