| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexandra Krol, Violeta G Lopez-Huerta, Taylor E C Corey, Karl Deisseroth, Jonathan T Ting, Guoping Fen. Two eARCHT3.0 Lines for Optogenetic Silencing of Dopaminergic and Serotonergic Neurons. Frontiers in neural circuits. vol 13. 2019-07-16. PMID:30774584. |
we have generated two bac transgenic mouse lines expressing the outward proton pump, enhanced archt3.0 (earcht3.0), and gfp under control of the regulatory elements of either the dopamine transporter (dat; jax# 031663) or the tryptophan hydroxylase 2 (tph2; jax# 031662) gene locus. |
2019-07-16 |
2023-08-13 |
mouse |
| Kyoungjune Pak, Seunghyeon Shin, So Jung Kim, Keunyoung Kim, Bum Soo Kim, Seong Jang Kim, In Joo Ki. Correlation of Plasma EGF with Striatal Dopamine Transporter Availability in Healthy Subjects. Scientific reports. vol 7. issue 1. 2019-06-28. PMID:29038492. |
we aimed to evaluate the association between plasma epidermal growth factor (egf) and the availability of dopamine transporter (dat) measured from |
2019-06-28 |
2023-08-13 |
human |
| Ken Ikeda, Masaru Yanagihashi, Ken Miura, Yuichi Ishikawa, Takehisa Hirayama, Takanori Takazawa, Osamu Kano, Kiyokazu Kawabe, Nao Mizumura, Yasuo Iwasak. Zonisamide cotreatment delays striatal dopamine transporter reduction in Parkinson disease: A retrospective, observational cohort study. Journal of the neurological sciences. vol 391. 2019-06-27. PMID:30103971. |
this study examined whether zonisamide (zns) cotreatment delays dopamine transporter (dat) reduction on spect in parkinson disease (pd) patients. |
2019-06-27 |
2023-08-13 |
human |
| Susana Paredes-Zúñiga, Nils Trost, Javiera F De la Paz, Julio Alcayaga, Miguel L Allend. Behavioral effects of triadimefon in zebrafish are associated with alterations of the dopaminergic and serotonergic pathways. Progress in neuro-psychopharmacology & biological psychiatry. vol 92. 2019-06-27. PMID:30593828. |
the lowest concentration does not alter neither locomotor activity nor dopamine levels but produced changes in the expression of two genes, tyrosine hydroxylase 1 (th1) and dopamine transporter (dat). |
2019-06-27 |
2023-08-13 |
zebrafish |
| Jong Hoon Won, Seok Kyun Kim, In Chul Shin, Hae Chan Ha, Ji Min Jang, Moon Jung Back, Dae Kyong Ki. Dopamine transporter trafficking is regulated by neutral sphingomyelinase 2/ceramide kinase. Cellular signalling. vol 44. 2019-06-26. PMID:29329781. |
the dopamine transporter (dat) has an important role in the regulation of da reuptake. |
2019-06-26 |
2023-08-13 |
mouse |
| Wei-Lun Sun, Pamela M Quizon, Yaxia Yuan, Wei Zhang, Subramaniam Ananthan, Chang-Guo Zhan, Jun Zh. Allosteric modulatory effects of SRI-20041 and SRI-30827 on cocaine and HIV-1 Tat protein binding to human dopamine transporter. Scientific reports. vol 7. issue 1. 2019-06-21. PMID:28623359. |
dopamine transporter (dat) is the target of cocaine and hiv-1 transactivator of transcription (tat) protein. |
2019-06-21 |
2023-08-13 |
human |
| Patrícia C R Rabelo, Nayara A C Horta, Letícia M S Cordeiro, Maristela O Poletini, Cândido C Coimbra, Raphael E Szawka, Danusa D Soare. Intrinsic exercise capacity in rats influences dopamine neuroplasticity induced by physical training. Journal of applied physiology (Bethesda, Md. : 1985). vol 123. issue 6. 2019-06-20. PMID:28883047. |
after that, concentrations of dopamine (da), serotonin (5-ht), and their metabolites and mrna levels of d1 receptor ( drd1), d2 receptor ( drd2), dopamine transporter ( dat), tyrosine hydroxylase ( th), glia cell line neurotrophic factor ( gdnf), and brain-derived neurotrophic factor ( bdnf) were determined in the caudate-putamen (cpu). |
2019-06-20 |
2023-08-13 |
rat |
| Luis M Tuesta, Mohamed N Djekidel, Renchao Chen, Falong Lu, Wengang Wang, Bernardo L Sabatini, Yi Zhan. In vivo nuclear capture and molecular profiling identifies Gmeb1 as a transcriptional regulator essential for dopamine neuron function. Nature communications. vol 10. issue 1. 2019-06-17. PMID:31175277. |
using this method, we identified gmeb1, a transcription factor predicted to regulate expression of th and dat, genes critical for dopamine synthesis and reuptake, respectively. |
2019-06-17 |
2023-08-13 |
Not clear |
| Linda D Simmler, Matthias E Liecht. Pharmacology of MDMA- and Amphetamine-Like New Psychoactive Substances. Handbook of experimental pharmacology. vol 252. 2019-06-13. PMID:29633178. |
amphetamine-like nps induce psychostimulation and euphoria mediated predominantly by norepinephrine (ne) and dopamine (da) transporter (net and dat) inhibition and transporter-mediated release of ne and da, thus showing a more catecholamine-selective profile. |
2019-06-13 |
2023-08-13 |
Not clear |
| Yasunori Mito, Ichiro Yabe, Hiroaki Yaguchi, Toshiki Takei, Satoshi Terae, Yasutaka Tajim. Relation of overactive bladder with motor symptoms and dopamine transporter imaging in drug-naïve Parkinson's disease. Parkinsonism & related disorders. vol 50. 2019-06-12. PMID:29449184. |
we therefore examined the relation of overactive bladder (oab) symptoms with motor symptoms and striatal dopamine transporter (dat) binding measured by [123-iodine]-fluoropropyl-2beta-carbomethoxy-3beta-(4-iodophenylnortropane) dopamine transporter single-photon emission computed tomography ( |
2019-06-12 |
2023-08-13 |
Not clear |
| Mariasole Ciampoli, Gabriella Contarini, Maddalena Mereu, Francesco Papale. Attentional Control in Adolescent Mice Assessed with a Modified Five Choice Serial Reaction Time Task. Scientific reports. vol 7. issue 1. 2019-06-11. PMID:28855580. |
these paradigms were also applied to two genetically modified lines: the dopamine transporter (dat) and catechol-o-methyltransferase (comt) heterozygous. |
2019-06-11 |
2023-08-13 |
mouse |
| Maarten E A Reith, Kymry T Jones, Juan Zhen, Sid Topio. Latch and trigger role for R445 in DAT transport explains molecular basis of DTDS. Bioorganic & medicinal chemistry letters. vol 28. issue 3. 2019-05-30. PMID:29258773. |
a recent study reports on five different mutations as sources of dopamine transporter (dat) deficiency syndrome (dtds). |
2019-05-30 |
2023-08-13 |
Not clear |
| Angélica Salatino-Oliveira, Luis A Rohde, Mara H Hut. The dopamine transporter role in psychiatric phenotypes. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 177. issue 2. 2019-05-28. PMID:28766921. |
the dopamine transporter (dat) is one of the most relevant and investigated neurotransmitter transporters. |
2019-05-28 |
2023-08-13 |
Not clear |
| Angélica Salatino-Oliveira, Luis A Rohde, Mara H Hut. The dopamine transporter role in psychiatric phenotypes. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 177. issue 2. 2019-05-28. PMID:28766921. |
dat is a plasma membrane protein which plays a homeostatic role, controlling both extracellular and intracellular concentrations of dopamine (da). |
2019-05-28 |
2023-08-13 |
Not clear |
| Tayyabah Yousaf, Gennaro Pagano, Flavia Niccolini, Marios Politi. Excessive daytime sleepiness may be associated with caudate denervation in Parkinson disease. Journal of the neurological sciences. vol 387. 2019-05-28. PMID:29571867. |
using the parkinson's progression markers initiative database, we performed a case-control study to investigate whether dopaminergic deficit is associated with the development of eds using dopaminergic specific single photon emission computed tomography (spect) molecular imaging of dopamine transporters (dat). |
2019-05-28 |
2023-08-13 |
Not clear |
| Asuka Nakajima, Yasushi Shimo, Satoko Sekimoto, Koji Kamagata, Takayuki Jo, Genko Oyama, Atsushi Umemura, Nobutaka Hattor. Dopamine transporter imaging predicts motor responsiveness to levodopa challenge in patients with Parkinson's disease: A pilot study of DATSCAN for subthalamic deep brain stimulation. Journal of the neurological sciences. vol 385. 2019-05-24. PMID:29406893. |
dopamine transporter (dat) imaging is a powerful tool for visualizing dopamine terminals in the striatum, but its usefulness in stn-dbs is unclear. |
2019-05-24 |
2023-08-13 |
Not clear |
| Phillip Mackie, Joe Lebowitz, Leila Saadatpour, Emily Nickoloff, Peter Gaskill, Habibeh Khoshboue. The dopamine transporter: An unrecognized nexus for dysfunctional peripheral immunity and signaling in Parkinson's Disease. Brain, behavior, and immunity. vol 70. 2019-05-21. PMID:29551693. |
the dopamine transporter (dat), the main regulator of dopaminergic tone in the cns, is known to exist in lymphocytes and monocytes/macrophages, but little is known about peripheral dat biology or how dat regulates the dopaminergic tone, much less how peripheral dat alters immune function. |
2019-05-21 |
2023-08-13 |
Not clear |
| Damiana Leo, Ilya Sukhanov, Francesca Zoratto, Placido Illiano, Lucia Caffino, Fabrizio Sanna, Giulia Messa, Marco Emanuele, Alessandro Esposito, Mariia Dorofeikova, Evgeny A Budygin, Liudmila Mus, Evgenia V Efimova, Marco Niello, Stefano Espinoza, Tatyana D Sotnikova, Marius C Hoener, Giovanni Laviola, Fabio Fumagalli, Walter Adriani, Raul R Gainetdino. Pronounced Hyperactivity, Cognitive Dysfunctions, and BDNF Dysregulation in Dopamine Transporter Knock-out Rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 8. 2019-05-20. PMID:29348190. |
the major function of the plasma membrane dopamine transporter (dat) is the rapid uptake of released da into presynaptic nerve terminals leading to control of both the extracellular levels of da and the intracellular stores of da. |
2019-05-20 |
2023-08-13 |
human |
| Phuong-Tram Nguyen, Duy-Khanh Dang, Hai-Quyen Tran, Eun-Joo Shin, Ji Hoon Jeong, Seung-Yeol Nah, Min Chang Cho, Yong Sup Lee, Choon-Gon Jang, Hyoung-Chun Ki. Methiopropamine, a methamphetamine analogue, produces neurotoxicity via dopamine receptors. Chemico-biological interactions. vol 305. 2019-05-10. PMID:30922767. |
moreover, treatment with mpa resulted in significant impairments in dopaminergic parameters [i.e., changes in dopamine level, dopamine turnover rate, tyrosine hydroxylase (th) levels, dopamine transporter (dat) expression, and vesicular monoamine transporter-2 (vmat-2) expression], and in behavioral deficits. |
2019-05-10 |
2023-08-13 |
mouse |
| Weiwei Wang, Ning Song, Fengjv Jia, Tingting Tang, Weiqi Bao, Chuantao Zuo, Junxia Xie, Hong Jian. Genomic DNA levels of mutant alpha-synuclein correlate with non-motor symptoms in an A53T Parkinson's disease mouse model. Neurochemistry international. vol 114. 2019-05-08. PMID:29355568. |
in the present work, we used littermate wt and heterozygous and homozygous a53t mice that were characterized by a modified genotyping protocol and observed a unilateral decline in the dopamine transporter (dat) distribution from 3 months to 12 months of age in homozygous mice. |
2019-05-08 |
2023-08-13 |
mouse |