| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Su Bong Nam, Keunyoung Kim, Bum Soo Kim, Hyung-Jun Im, Seung Hun Lee, Seong-Jang Kim, In Joo Kim, Kyoungjune Pa. The Effect of Obesity on the Availabilities of Dopamine and Serotonin Transporters. Scientific reports. vol 8. issue 1. 2019-09-26. PMID:29563547. |
the authors investigated relations between obesity, age, and sex and the availabilities of striatal dopamine transporter (dat) and extrastriatal serotonin transporter (sert) by |
2019-09-26 |
2023-08-13 |
Not clear |
| Ken Ikeda, Junya Ebina, Kiyokazu Kawabe, Yasuo Iwasak. Dopamine Transporter Imaging in Parkinson Disease: Progressive Changes and Therapeutic Modification after Anti-parkinsonian Medications. Internal medicine (Tokyo, Japan). vol 58. issue 12. 2019-09-24. PMID:30799370. |
dopamine transporter (dat) imaging is widely performed for the differential diagnosis of pd and other degenerative parkinsonism from essential tremor, vascular parkinsonism, and drug-induced parkinsonism. |
2019-09-24 |
2023-08-13 |
Not clear |
| Ken Ikeda, Junya Ebina, Kiyokazu Kawabe, Yasuo Iwasak. Dopamine Transporter Imaging in Parkinson Disease: Progressive Changes and Therapeutic Modification after Anti-parkinsonian Medications. Internal medicine (Tokyo, Japan). vol 58. issue 12. 2019-09-24. PMID:30799370. |
dat is the plasma membrane carrier specific to dopamine neurons that are responsible for re-uptaking dopamine from the synaptic cleft back into the nerve ending. |
2019-09-24 |
2023-08-13 |
Not clear |
| Akihiro Shiokawa, Masahisa Onoguchi, Takayuki Shibutani, Yuta Maeda, Hiroto Yoneyama, Takahiro Konishi, Hiroshi Wakabayash. [Influence of the Each Correction Method for the Specific Binding Ratio and Standardized Uptake Value in the Dopamine Transporter SPECT]. Nihon Hoshasen Gijutsu Gakkai zasshi. vol 75. issue 7. 2019-09-12. PMID:31327774. |
this study was to reveal the characteristics for each correction effect of specific binding ratio (sbr) and standardized uptake value (suv) in the dopamine transporter (dat) single photon emission computed tomography (spect). |
2019-09-12 |
2023-08-13 |
Not clear |
| Hua Wang, Anzari Atik, Tessandra Stewart, Carmen Ginghina, Patrick Aro, Kathleen F Kerr, John Seibyl, Danna Jennings, Poul Henning Jensen, Kenneth Marek, Min Shi, Jing Zhan. Plasma α-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome: A pilot study. Neurobiology of disease. vol 116. 2019-09-06. PMID:29705185. |
the results demonstrated that baseline and longitudinal increases in total α-synuclein predicted progression of cognitive decline in hyposmic individuals with dopamine transporter (dat) binding reduction. |
2019-09-06 |
2023-08-13 |
Not clear |
| Juliana R Bastos, Katherinne M Perico, Érica L Marciano Vieira, Antônio L Teixeira, Fabiana S Machado, Aline S de Miranda, Fabrício A Moreir. Inhibition of the dopamine transporter as an animal model of bipolar disorder mania: Locomotor response, neuroimmunological profile and pharmacological modulation. Journal of psychiatric research. vol 102. 2019-08-29. PMID:29656188. |
inhibition of dopamine transporter (dat) by gbr12909 has been proposed as a pharmacological model of mania related to bipolar disorder (bd). |
2019-08-29 |
2023-08-13 |
mouse |
| Jose Luiz Costa, Kelly Francisco Cunha, Rafael Lanaro, Ricardo Leal Cunha, Donna Walther, Michael H Bauman. Analytical quantification, intoxication case series, and pharmacological mechanism of action for N-ethylnorpentylone (N-ethylpentylone or ephylone). Drug testing and analysis. vol 11. issue 3. 2019-08-27. PMID:30207090. |
the activity of n-ethylnorpentylone at plasma membrane transporters for dopamine (dat), norepinephrine (net) and 5-ht (sert) was assessed using in vitro assays measuring uptake inhibition and evoked release of [ |
2019-08-27 |
2023-08-13 |
human |
| J A Suyama, M L Banks, S S Negu. Effects of repeated treatment with methcathinone, mephedrone, and fenfluramine on intracranial self-stimulation in rats. Psychopharmacology. vol 236. issue 3. 2019-08-27. PMID:30232529. |
synthetic cathinones constitute a class of abused drugs that can act at dopamine, norepinephrine, and serotonin transporters (dat, net, and sert, respectively). |
2019-08-27 |
2023-08-13 |
rat |
| Elisabeth Piccart, Christopher W Tschumi, Michael J Beckstea. Acute and subchronic PCP attenuate D2 autoreceptor signaling in substantia nigra dopamine neurons. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 3. 2019-08-26. PMID:30686631. |
acute pcp affected d2 autoreceptor-mediated currents through two apparently distinct mechanisms: a low-concentration dopamine transporter (dat) inhibition and a high-concentration potassium (girk) channel inhibition. |
2019-08-26 |
2023-08-13 |
Not clear |
| Yuan Chen, Brendan Vastenhouw, Chao Wu, Marlies C Goorden, Freek J Beekma. Optimized image acquisition for dopamine transporter imaging with ultra-high resolution clinical pinhole SPECT. Physics in medicine and biology. vol 63. issue 22. 2019-08-22. PMID:30403197. |
spect can be used to image dopamine transporter (dat) availability in the human striatum, e.g. |
2019-08-22 |
2023-08-13 |
human |
| Christine Muench, Corinde E Wiers, Carlos R Cortes, Reza Momenan, Falk W Lohof. Dopamine Transporter Gene Methylation is Associated with Nucleus Accumbens Activation During Reward Processing in Healthy but not Alcohol-Dependent Individuals. Alcoholism, clinical and experimental research. vol 42. issue 1. 2019-08-14. PMID:29030974. |
alcohol's reinforcement is mediated by dopamine signaling in the ventral striatum, which is modulated by the dopamine transporter (dat). |
2019-08-14 |
2023-08-13 |
Not clear |
| Qing-Rong Liu, Ana Canseco-Alba, Hai-Ying Zhang, Patricia Tagliaferro, Monika Chung, Eugene Dennis, Branden Sanabria, Norman Schanz, Joao Carlos Escosteguy-Neto, Hiroki Ishiguro, Zhicheng Lin, Susan Sgro, Claire M Leonard, Jair Guilherme Santos-Junior, Eliot L Gardner, Josephine M Egan, Jeung Woon Lee, Zheng-Xiong Xi, Emmanuel S Onaiv. Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference. Scientific reports. vol 7. issue 1. 2019-08-06. PMID:29234141. |
therefore, we generated cnr2-floxed mice that were crossed with dat-cre mice, in which cre- recombinase expression is under dopamine transporter gene (dat) promoter control to ablate cnr2 gene in midbrain da neurons of dat-cnr2 conditional knockout (cko) mice. |
2019-08-06 |
2023-08-13 |
mouse |
| Alberto Llera, Ismael Huertas, Pablo Mir, Christian F Beckman. Quantitative Intensity Harmonization of Dopamine Transporter SPECT Images Using Gamma Mixture Models. Molecular imaging and biology. vol 21. issue 2. 2019-08-01. PMID:29987621. |
differences in site, device, and/or settings may cause large variations in the intensity profile of dopamine transporter (dat) single-photon emission computed tomography (spect) images. |
2019-08-01 |
2023-08-13 |
Not clear |
| Siew Hoong Yip, Jade York, Brian Hyland, Stephen J Bunn, David R Gratta. Incomplete concordance of dopamine transporter Cre (DAT Journal of chemical neuroanatomy. vol 90. 2019-07-29. PMID:29217488. |
incomplete concordance of dopamine transporter cre (dat co-localization of the expression of the dopamine transporter (dat) with the catecholamine synthesising enzyme tyrosine hydroxylase (th) has been investigated using transgenic mice expressing cre recombinase (cre) dependent green fluorescent protein (gfp) under the control of the dat promoter (dat |
2019-07-29 |
2023-08-13 |
mouse |
| Weimin C Hong, Michael J Wasko, Derek S Wilkinson, Takato Hiranita, Libin Li, Shuichiro Hayashi, David B Snell, Jeffry D Madura, Christopher K Surratt, Jonathan L Kat. Dopamine Transporter Dynamics of The Journal of pharmacology and experimental therapeutics. vol 366. issue 3. 2019-07-29. PMID:29945932. |
dopamine transporter dynamics of atypical dopamine transporter (dat) inhibitors, despite high dat affinity, do not produce the psychomotor stimulant and abuse profile of standard dat inhibitors such as cocaine. |
2019-07-29 |
2023-08-13 |
Not clear |
| Tatiana Sorkina, Shiqi Ma, Mads Breum Larsen, Simon C Watkins, Alexander Sorki. Small molecule induced oligomerization, clustering and clathrin-independent endocytosis of the dopamine transporter. eLife. vol 7. 2019-07-22. PMID:29630493. |
we found that the cell-permeable furopyrimidine aim-100 promotes dramatic oligomerization, clustering and cie of human and mouse dopamine transporters (dat), but not of their close homologues, norepinephrine and serotonin transporters. |
2019-07-22 |
2023-08-13 |
mouse |
| Manfred Gerlach, Manu Sharma, Marcel Romanos, Klaus-Peter Lesch, Susanne Walitza, H Annette Conzelmann, Rejko Krüger, Tobias J Renne. Family-based association study on functional α-synuclein polymorphisms in attention-deficit/hyperactivity disorder. Attention deficit and hyperactivity disorders. vol 11. issue 1. 2019-07-19. PMID:30927235. |
α-synuclein, a protein located primarily in the presynaptic vesicles, has been suggested to play a role in the modulation of dopamine transporter (dat) function. |
2019-07-19 |
2023-08-13 |
Not clear |
| Manfred Gerlach, Manu Sharma, Marcel Romanos, Klaus-Peter Lesch, Susanne Walitza, H Annette Conzelmann, Rejko Krüger, Tobias J Renne. Family-based association study on functional α-synuclein polymorphisms in attention-deficit/hyperactivity disorder. Attention deficit and hyperactivity disorders. vol 11. issue 1. 2019-07-19. PMID:30927235. |
dat is the target of psychostimulants for the treatment of adhd and plays a key role in regulating the dopamine concentrations in the synaptic cleft. |
2019-07-19 |
2023-08-13 |
Not clear |
| Caline S Karam, Jonathan A Javitc. Phosphorylation of the Amino Terminus of the Dopamine Transporter: Regulatory Mechanisms and Implications for Amphetamine Action. Advances in pharmacology (San Diego, Calif.). vol 82. 2019-07-17. PMID:29413521. |
amphs target the dopamine transporter (dat), the plasmalemmal membrane protein that mediates the inactivation of released dopamine (da) through its reuptake. |
2019-07-17 |
2023-08-13 |
Not clear |
| Caline S Karam, Jonathan A Javitc. Phosphorylation of the Amino Terminus of the Dopamine Transporter: Regulatory Mechanisms and Implications for Amphetamine Action. Advances in pharmacology (San Diego, Calif.). vol 82. 2019-07-17. PMID:29413521. |
amphs act as substrates for dat and are known to cause mobilization of dopamine (da) to the cell exterior via dat-mediated reverse transport (efflux). |
2019-07-17 |
2023-08-13 |
Not clear |