| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katsumasa Muneoka, Makiko Kuwagata, Masaaki Iwata, Yukihiko Shirayama, Tetsuo Ogawa, Morikuni Takigaw. Dopamine transporter density and behavioral response to methylphenidate in a hyperlocomotor rat model. Congenital anomalies. vol 46. issue 3. 2006-10-11. PMID:16922923. |
using this model, we investigated dopamine transporter (dat) density and behavioral outcomes in brdu-rats, some of which were also administered methylphenidate, a psychostimulant that is widely used for the treatment of adhd. |
2006-10-11 |
2023-08-12 |
rat |
| Rui Li, Ning Peng, Xu-Ping Li, Wei-Dong L. (-)-Epigallocatechin gallate regulates dopamine transporter internalization via protein kinase C-dependent pathway. Brain research. vol 1097. issue 1. 2006-10-06. PMID:16733047. |
dopamine transporter (dat) provides not only an integral component of dopaminergic neurotransmission but also a molecular gateway for the accumulation of some neurotoxins such as 1-methyl-4-phenylpyridinium (mpp(+)), a metabolite of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (mptp). |
2006-10-06 |
2023-08-12 |
Not clear |
| Rui Li, Ning Peng, Xu-Ping Li, Wei-Dong L. (-)-Epigallocatechin gallate regulates dopamine transporter internalization via protein kinase C-dependent pathway. Brain research. vol 1097. issue 1. 2006-10-06. PMID:16733047. |
furthermore, protein kinase c (pkc) inhibitor gf109203x at 2 microm can markedly diminish the inhibitory effects of egcg on dopamine uptake and reverse the egcg-induced internalization of dat. |
2006-10-06 |
2023-08-12 |
Not clear |
| Jason R Richardson, W Michael Caudle, Minzheng Wang, E Danielle Dean, Kurt D Pennell, Gary W Mille. Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 10. 2006-10-05. PMID:16809432. |
at 12 wk of age, protein and mrna levels of the dopamine transporter (dat) and vesicular monoamine transporter 2 (vmat2) were increased by perinatal dieldrin exposure in a dose-related manner. |
2006-10-05 |
2023-08-12 |
mouse |
| Jason R Richardson, W Michael Caudle, Minzheng Wang, E Danielle Dean, Kurt D Pennell, Gary W Mille. Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 10. 2006-10-05. PMID:16809432. |
we then administered mptp (2 x 10 mg/kg s.c) at 12 wk of age and observed a greater reduction of striatal dopamine in dieldrin-exposed offspring, which was associated with a greater dat:vmat2 ratio. |
2006-10-05 |
2023-08-12 |
mouse |
| Ole V Mortensen, Susan G Amar. Gain of function mutants reveal sites important for the interaction of the atypical inhibitors benztropine and bupropion with monoamine transporters. Journal of neurochemistry. vol 98. issue 5. 2006-10-03. PMID:16923164. |
taking advantage of the differential sensitivity of the dopamine and the norepinephrine transporters (dat and net) to benztropine and bupropion, we have used site-directed mutagenesis to produce gain-of-function mutants in net which demonstrate that ala279 in the trans-membrane domain 5 (tm5) and ser359 in the tm7 of dat are responsible for the higher sensitivity of dat to both bupropion and benztropine. |
2006-10-03 |
2023-08-12 |
Not clear |
| Agata Adamczyk, Anna Kaźmierczak, Joanna B Strosznajde. Alpha-synuclein and its neurotoxic fragment inhibit dopamine uptake into rat striatal synaptosomes. Relationship to nitric oxide. Neurochemistry international. vol 49. issue 4. 2006-10-02. PMID:16546300. |
the aim of this study was to determine the effect of brain aging and the role of asn and nac peptide on striatal dopamine transporter (dat) function. |
2006-10-02 |
2023-08-12 |
rat |
| W Michael Caudle, Jason R Richardson, Kristin C Delea, Thomas S Guillot, Minzheng Wang, Kurt D Pennell, Gary W Mille. Polychlorinated biphenyl-induced reduction of dopamine transporter expression as a precursor to Parkinson's disease-associated dopamine toxicity. Toxicological sciences : an official journal of the Society of Toxicology. vol 92. issue 2. 2006-09-29. PMID:16702228. |
however, we did observe a dramatic dose-dependent decrease in striatal dopamine transporter (dat) levels. |
2006-09-29 |
2023-08-12 |
human |
| Nagendra V Chemuturi, Jon E Haraldsson, Thomas Prisinzano, Maureen Donova. Role of dopamine transporter (DAT) in dopamine transport across the nasal mucosa. Life sciences. vol 79. issue 14. 2006-09-29. PMID:16733058. |
role of dopamine transporter (dat) in dopamine transport across the nasal mucosa. |
2006-09-29 |
2023-08-12 |
cattle |
| Nagendra V Chemuturi, Jon E Haraldsson, Thomas Prisinzano, Maureen Donova. Role of dopamine transporter (DAT) in dopamine transport across the nasal mucosa. Life sciences. vol 79. issue 14. 2006-09-29. PMID:16733058. |
portions of the nasal mucosa are innervated by olfactory neurons expressing dopamine transporter (dat) which is responsible for the uptake of dopamine within the central nervous system. |
2006-09-29 |
2023-08-12 |
cattle |
| Nagendra V Chemuturi, Jon E Haraldsson, Thomas Prisinzano, Maureen Donova. Role of dopamine transporter (DAT) in dopamine transport across the nasal mucosa. Life sciences. vol 79. issue 14. 2006-09-29. PMID:16733058. |
the objective of these studies was to study the role of dat in dopamine transport across the bovine olfactory and nasal respiratory mucosa. |
2006-09-29 |
2023-08-12 |
cattle |
| Nagendra V Chemuturi, Jon E Haraldsson, Thomas Prisinzano, Maureen Donova. Role of dopamine transporter (DAT) in dopamine transport across the nasal mucosa. Life sciences. vol 79. issue 14. 2006-09-29. PMID:16733058. |
bidirectional transport studies over a 0.1-1 mm dopamine concentration range were carried out in the mucosal-submucosal and submucosal-mucosal directions to quantify dat activity, and additional transport studies investigating the ability of gbr 12909, a dat inhibitor, to decrease dopamine transport were conducted. |
2006-09-29 |
2023-08-12 |
cattle |
| Nagendra V Chemuturi, Jon E Haraldsson, Thomas Prisinzano, Maureen Donova. Role of dopamine transporter (DAT) in dopamine transport across the nasal mucosa. Life sciences. vol 79. issue 14. 2006-09-29. PMID:16733058. |
these studies demonstrate the activity of dat in the nasal mucosa and provide evidence that dat-mediated dopamine uptake plays a role in the absorption and distribution of dopamine following intranasal administration. |
2006-09-29 |
2023-08-12 |
cattle |
| Jack D Shepard, David T Chuang, Yavin Shaham, Marisela Morale. Effect of methamphetamine self-administration on tyrosine hydroxylase and dopamine transporter levels in mesolimbic and nigrostriatal dopamine pathways of the rat. Psychopharmacology. vol 185. issue 4. 2006-09-28. PMID:16555063. |
we studied the effect of methamphetamine self-administration on two key regulators of dopamine transmission, tyrosine hydroxylase (th), and dopamine transporter (dat), in components of the mesolimbic and nigrostriatal dopamine pathways. |
2006-09-28 |
2023-08-12 |
rat |
| Rainald Mössner, Rabi Simantov, Alexander Marx, Klaus Peter Lesch, Isabelle Sei. Aberrant accumulation of serotonin in dopaminergic neurons. Neuroscience letters. vol 401. issue 1-2. 2006-09-28. PMID:16638624. |
by additional ablation of the dopamine transporter (dat), this aberrant 5-ht accumulation was abolished in maoa/5-htt/dat triple knockout mice. |
2006-09-28 |
2023-08-12 |
mouse |
| Pansiri Phansuwan-Pujito, Parichart Boontem, Banthit Chetsawang, Manuchair Ebadi, Piyarat Govitrapon. Dopamine transporter immunoreactive terminals in the bovine pineal gland. Neuroscience letters. vol 403. issue 1-2. 2006-09-28. PMID:16781060. |
recently, the site of dopamine transporter (dat), a plasma membrane transport protein of dopaminergic neuron, also has been characterized in the bovine pineal gland. |
2006-09-28 |
2023-08-12 |
cattle |
| Pansiri Phansuwan-Pujito, Parichart Boontem, Banthit Chetsawang, Manuchair Ebadi, Piyarat Govitrapon. Dopamine transporter immunoreactive terminals in the bovine pineal gland. Neuroscience letters. vol 403. issue 1-2. 2006-09-28. PMID:16781060. |
the colocalization of dat with tyrosine hydroxylase (th) or dopamine beta hydroxylase (dbh) immunoreactivities was observed in nerve terminals. |
2006-09-28 |
2023-08-12 |
cattle |
| Cristina M Bäckman, Nasir Malik, Yajun Zhang, Lufei Shan, Alex Grinberg, Barry J Hoffer, Heiner Westphal, Andreas C Toma. Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus. Genesis (New York, N.Y. : 2000). vol 44. issue 8. 2006-09-28. PMID:16865686. |
the dopamine transporter (dat) is highly expressed in dopaminergic neurons of the ventral mesencephalon and regulates neurotransmission by transporting da back into the presynaptic terminals. |
2006-09-28 |
2023-08-12 |
mouse |
| F Mignini, E Traini, D Tomassoni, F Ament. Dopamine plasma membrane transporter (DAT) in rat thymus and spleen: an immunochemical and immunohistochemical study. Autonomic & autacoid pharmacology. vol 26. issue 2. 2006-09-27. PMID:16553646. |
dopamine plasma membrane transporter (dat) in rat thymus and spleen: an immunochemical and immunohistochemical study. |
2006-09-27 |
2023-08-12 |
rat |
| F Mignini, E Traini, D Tomassoni, F Ament. Dopamine plasma membrane transporter (DAT) in rat thymus and spleen: an immunochemical and immunohistochemical study. Autonomic & autacoid pharmacology. vol 26. issue 2. 2006-09-27. PMID:16553646. |
the expression of the dopamine plasma membrane transporter (dat) was investigated in rat thymus and spleen by immunochemical and immunohistochemical techniques. |
2006-09-27 |
2023-08-12 |
rat |