| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S N Kim, S Y Kim, H K Yim, W Y Lee, K S Ham, S K Kim, M Y Yoon, Y C Ki. Effect of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2'- dicarboxylate (DDB) on chemical-induced liver injury. Biological & pharmaceutical bulletin. vol 22. issue 1. 1999-03-29. PMID:9989671. |
in female rats as indicated by increases in the activity of alanine aminotransferase (alt), aspartate aminotransferase (ast) and sorbitol dehydrogenase (sdh) in serum. |
1999-03-29 |
2023-08-12 |
mouse |
| C H Cottart, L Do, M C Blanc, M Vaubourdolle, G Descamps, D Durand, F X Galen, J P Clo. Hepatoprotective effect of endogenous nitric oxide during ischemia-reperfusion in the rat. Hepatology (Baltimore, Md.). vol 29. issue 3. 1999-03-29. PMID:10051483. |
injury to hepatocytes and endothelial cells was evaluated by determining cytolysis-marker activity in plasma (alanine transaminase [alt]; aspartate transaminase [ast]) and plasma hyaluronic acid (ha) concentration. |
1999-03-29 |
2023-08-12 |
rat |
| G Hessel, E F Collare. Gastric emptying in rats with acetaminophen-induced hepatitis. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 31. issue 9. 1999-03-25. PMID:9876280. |
twenty-four hours later, the ge of the three test meals was assessed and blood samples were collected to measure the serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast) and acetaminophen. |
1999-03-25 |
2023-08-12 |
rat |
| B Kuru, S Yilmaz, U Noyan, O Acar, T Kadi. Microbiological features and crevicular fluid aspartate aminotransferase enzyme activity in early onset periodontitis patients. Journal of clinical periodontology. vol 26. issue 1. 1999-03-25. PMID:9923506. |
aspartate aminotransferase enzyme (ast) is one of the components of gcf that is released as a result of cell death. |
1999-03-25 |
2023-08-12 |
Not clear |
| J Tharakan, A Hossenbocus, M J Arthu. Macromolecular aspartate aminotransferase. European journal of gastroenterology & hepatology. vol 10. issue 12. 1999-03-18. PMID:9895054. |
serum ast (aspartate aminotransferase) has rarely been reported to complex with immunoglobulins, resulting in an elevation in serum ast activity. |
1999-03-18 |
2023-08-12 |
Not clear |
| A J Eraso, I Albes. Elevation of alanine amino transferase and aspartate amino transferase produced by pyoverdin, a photolabile pigment of Pseudomonas fluorescens. Natural toxins. vol 6. issue 2. 1999-03-11. PMID:9888631. |
significant increases of alanine amino transferase (alt) and aspartate amino transferase (ast) were obtained in mice after ingestion of water with forms a and c. the effect on liver was more evident with a than with c. pyoverdin was purified by means of salt saturation, solvent extractions and ion-exchange chromatography. |
1999-03-11 |
2023-08-12 |
mouse |
| P E Goss, C L Reid, D Bailey, J W Denni. Phase IB clinical trial of the oligosaccharide processing inhibitor swainsonine in patients with advanced malignancies. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 3. issue 7. 1999-02-25. PMID:9815786. |
significant toxicities included edema and elevated serum aspartate aminotransferase (ast). |
1999-02-25 |
2023-08-12 |
mouse |
| S Inkatanuvat, P Suntharasamai, S Vutikes, M Rigant. Changes of liver functions after albendazole treatment in human gnathostomiasis. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. vol 81. issue 10. 1999-02-16. PMID:9803063. |
there was a statistically significant increase of total protein, albumin, alkaline phosphatase (alp), aspartate aminotransferase (ast) and alanine aminotransferase (alt) values when comparing the different periods. |
1999-02-16 |
2023-08-12 |
human |
| P Y Wang, T Kaneko, Y Wang, A Sat. Acarbose alone or in combination with ethanol potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen in rats. Hepatology (Baltimore, Md.). vol 29. issue 1. 1999-02-03. PMID:9862862. |
the 40- or 80-mg/100 g acarbose diet alone potentiated ccl4 and ap hepatotoxicity, as evidenced by significantly increased levels of both alanine transaminase (alt) and aspartate transaminase (ast) in the plasma of rats pretreated with acarbose. |
1999-02-03 |
2023-08-12 |
rat |
| I Yeruham, Y Avidar, S Perl, B Yakobson, A Shlosberg, V Hanji, E Bogi. Probable toxicosis in cattle in Israel caused by the oak Quercus calliprinos. Veterinary and human toxicology. vol 40. issue 6. 1999-01-29. PMID:9830693. |
the clinical-pathological findings revealed increases in blood urea, creatinine, aspartate aminotransferase (ast), gamma-glutamyltransferase (ggt), creatine kinase (ck), lactate dehydrogenase (ldh) and inorganic phosphorus. |
1999-01-29 |
2023-08-12 |
cattle |
| F W Wong, W Y Chan, S S Le. Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression. Toxicology and applied pharmacology. vol 153. issue 1. 1999-01-21. PMID:9875305. |
injection of 1 ml/kg (= 1.59 g/kg) ccl4 and 24 h later liver injury was assessed by elevations of serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities and histopathology. |
1999-01-21 |
2023-08-12 |
mouse |
| Z L Jiang, T Harada, M Yokokawa, M Kohzuki, T Sat. Muscle damage induced by experimental hypoglycemia. Metabolism: clinical and experimental. vol 47. issue 12. 1999-01-13. PMID:9867076. |
serum activity of alanine aminotransferase (alt), aspartate aminotransferase (ast), and lactate dehydrogenase (ldh) increased only in group b10. |
1999-01-13 |
2023-08-12 |
Not clear |
| K Atici, N Yamalik, K Eratalay, I Etika. Analysis of gingival crevicular fluid intracytoplasmic enzyme activity in patients with adult periodontitis and rapidly progressive periodontitis. A longitudinal study model with periodontal treatment. Journal of periodontology. vol 69. issue 10. 1999-01-12. PMID:9802716. |
in the present study, the activity of 3 functionally related enzymes, creatine kinase (ck), lactate dehydrogenase (ldh), and aspartate aminotransferase (ast) levels in the rest and flow gingival crevicular fluid (rgcf, fgcf) from patients with rapidly progressive periodontitis (rpp) and adult periodontitis (ap) were determined before and after periodontal treatment, including maintenance. |
1999-01-12 |
2023-08-12 |
Not clear |
| C J Waterfield, C Westmoreland, D S Asker, J C Murdock, E George, J A Timbrel. Ethionine toxicity in vitro: the correlation of data from rat hepatocyte suspensions and monolayers with in vivo observations. Archives of toxicology. vol 72. issue 9. 1999-01-07. PMID:9806431. |
the following markers were measured in the appropriate system: (1) neutral red uptake; 3-(4,5 dimethyl)thiazol-2-yl,-2,5-diphenyl tetrazolium bromide (mtt) reduction; lactate dehydrogenase (ldh), aspartate aminotransferase (ast) and alanine aminotransferase (alt) leakage (cytotoxicity). |
1999-01-07 |
2023-08-12 |
rat |
| S Nazifi, K Malek. Biochemical analysis of serum and cerebrospinal fluid in clinically normal adult camels (Camelus dromedarius). Research in veterinary science. vol 65. issue 1. 1998-12-18. PMID:9769078. |
the concentrations of total protein, glucose, cholesterol, triglyceride, urea nitrogen, creatinine, sodium, potassium, chloride, calcium, inorganic phosphorus, copper, magnesium, and iron and the activities of aspartate aminotransferase (ast), alanine aminotransferase, (alt), alkaline phosphatase (alp), lactate dehydrogenase (ld), creatine kinase (ck) and amylase were determined in cerebrospinal fluid (csf) and serum from 21 clinically healthy adult camels. |
1998-12-18 |
2023-08-12 |
Not clear |
| I Cepelak, T Zanić Grubisić, A Mandusić, B Rekić, J Lenice. Valproate and carbamazepine comedication changes hepatic enzyme activities in sera of epileptic children. Clinica chimica acta; international journal of clinical chemistry. vol 276. issue 2. 1998-12-17. PMID:9764730. |
this study compares alanine aminotransferase (alt), aspartate aminotransferase (ast) and gamma-glutamyltransferase (ggt) activities in sera of children treated with vpa (n=42), or cbz (n=36) taken as a monotherapy, with vpa + cbz combined therapy (n=36). |
1998-12-17 |
2023-08-12 |
Not clear |
| V Arndt, H Brenner, D Rothenbacher, B Zschenderlein, E Fraisse, T M Fliedne. Elevated liver enzyme activity in construction workers: prevalence and impact on early retirement and all-cause mortality. International archives of occupational and environmental health. vol 71. issue 6. 1998-12-10. PMID:9766914. |
gamma-glutamyl transferase (ggt), alanine transaminase (alt), and aspartate transaminase (ast) are widely used as markers of hepatobiliary disorders in occupational health surveillance. |
1998-12-10 |
2023-08-12 |
Not clear |
| D E Amacher, L M Fasulo, C Charuel, P Comby, K Beaumon. In vitro toxicity of zamifenacin (UK-76,654) and metabolites in primary hepatocyte cultures. Xenobiotica; the fate of foreign compounds in biological systems. vol 28. issue 9. 1998-12-03. PMID:9764931. |
the rapid onset of cytotoxicity indicated by elevations of alanine aminotransferase (alt), aspartate aminotransferase (ast) and other markers in the medium after uk-82,201 exposure, the delayed but substantial cytotoxic response to the parent drug which was suggestive of biotransformation to a reactive moiety, in vivo and in vitro drug metabolism results and subacute toxicology data suggest that dog may more effectively transform zamifenacin into uk-82,201, which is relatively hepatotoxic. |
1998-12-03 |
2023-08-12 |
rat |
| U Juárez, W Trejo, M Whente, G Contreras, M Cárdenas, P A Reye. [The usefulness of determining myoglobin, creatine phosphokinase MB isoenzyme, lactate dehydrogenase and aspartate aminotransferase in the diagnosis of acute myocardial infarct]. Archivos del Instituto de Cardiologia de Mexico. vol 68. issue 3. 1998-11-25. PMID:9810342. |
diagnosis of acute myocardial infarction is made with the aid of biomarkers such as structural myocardial proteins, myoglobin (mg) or specific enzymes, creatine phosphokinase isoenzyme mb (ck-mb) or non specific enzymes, lactic dehydrogenase (dhl) and aspartate aminotransferase (ast). |
1998-11-25 |
2023-08-12 |
Not clear |
| G Gavazzi, G Richallet, P Morand, O Bouchard, A Bosseray, P Leclercq, M Micou. [Effects of double and triple antiretroviral agents on the HCV viral load in patients coinfected with HIV and HCV]. Pathologie-biologie. vol 46. issue 6. 1998-11-20. PMID:9769871. |
hcv and hiv viral load, lymphocyte cd4 counts, alanine aminotransferase (alt) and aspartate amino transferase (ast) were measured before and 3 months after starting treatment in 2 groups: group 1 (n = 15) treated with 2 nucleoside analogues and group 2 (n = 15) treated with 2 nucleoside analogues and a protease inhibitor. |
1998-11-20 |
2023-08-12 |
Not clear |