| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chuen-Lan Liu, Jin-Ming Wang, Chia-Yih Chu, Ming-Tzong Cheng, Tsui-Hwa Tsen. In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 40. issue 5. 2002-06-21. PMID:11955669. |
our investigation showed that pretreatment with pca (50-100 mg/kg) by gavage for 5 days before a single dose of t-bhp (ip; 0.2 mmol/kg ) significantly lowered serum levels of the hepatic enzyme markers lactate dehydrogenase (ldh) and alanine (alt) and aspartate (ast) aminotransferase, and reduced oxidative stress of the liver by evaluating malondialdehyde (mda) and glutathione (gsh). |
2002-06-21 |
2023-08-12 |
rat |
| C Villani, S Conte, F Chiozzi, C Iandolo, P Persian. Prevalence of hepatitis B and hepatitis C in an orthopaedics and traumatology ward. La Chirurgia degli organi di movimento. vol 86. issue 2. 2002-06-21. PMID:12025049. |
patients were also tested for measurement of liver enzymes, aspartate aminotransferase (ast), alanine aminotransferase (alt), and hepatitis b virus surface antigen (hbsag). |
2002-06-21 |
2023-08-12 |
Not clear |
| T P Endy, S Narupiti, K S Myint, S Suntayakorn, R A Kuschner, D W Vaugh. TT virus infection in acute non-A to E hepatitis in northern Thailand. The Southeast Asian journal of tropical medicine and public health. vol 32. issue 4. 2002-06-14. PMID:12041559. |
among subjects with non-a-e hepatitis, ttv was associated with higher alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels (significant for ast, p = 0.02). |
2002-06-14 |
2023-08-12 |
human |
| Takako Miyamae, Tomoyuki Imagawa, Shigeki Katakura, Masaaki Mori, Shumpei Yokota, Kiyoshi Yasui, Yuko Aihar. [A case of classical polyarteritis nodosa diagnosed by myocardial biopsy]. Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology. vol 25. issue 2. 2002-06-14. PMID:12043186. |
electrocardiogram indicated the elevation of st-t levels and low voltage, and blood examination showed remarkable elevation of creatine phosphokinase (ck), white blood cell count (wbc), aspartate aminotransferase (ast) and lactic dehydrogenase (ldh) levels. |
2002-06-14 |
2023-08-12 |
Not clear |
| M Grassi, A Mammarella, G Sagliaschi, L Granati, A Musca, F Traditi, M Pezzell. Persistent hepatitis G virus (HGV) infection in chronic hemodialysis patients and non-B, non-C chronic hepatitis. Clinical chemistry and laboratory medicine. vol 39. issue 10. 2002-05-29. PMID:11758610. |
hgv-infected hemodialyzed patients and hgv viremic blood donors had serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels within normal limits. |
2002-05-29 |
2023-08-12 |
Not clear |
| H Walter, I Hertling, N Benda, B König, K Ramskogler, A Riegler, B Semler, A Zoghlami, O M Lesc. Sensitivity and specificity of carbohydrate-deficient transferrin in drinking experiments and different patients. Alcohol (Fayetteville, N.Y.). vol 25. issue 3. 2002-05-29. PMID:11839465. |
we found a significant correlation between results on the munich alcoholism test (malt) and mcv levels; among gamma-glutamyltransferase (ggt), aspartate aminotransferase (ast), and alanine aminotransferase (alt) levels; and among all four cdt variants. |
2002-05-29 |
2023-08-12 |
Not clear |
| P C Sharp. Biochemical detection and monitoring of alcohol abuse and abstinence. Annals of clinical biochemistry. vol 38. issue Pt 6. 2002-05-28. PMID:11732647. |
the traditional markers discussed include gamma-glutamyltransferase (ggt), aspartate and alanine aminotransaminases (ast, alt) and mean corpuscular volume (mcv); new markers include mitochondrial ast, carbohydrate-deficient transferrin (cdt), serum/urine 5-hydroxytryptophol, beta-hexosaminidase and acetaldehyde adducts. |
2002-05-28 |
2023-08-12 |
Not clear |
| A B Osvaldt, P Viero, M S Borges da Costa, L R Wendt, V P Bersch, L Rohd. Evaluation of Ranson, Glasgow, APACHE-II, and APACHE-O criteria to predict severity in acute biliary pancreatitis. International surgery. vol 86. issue 3. 2002-05-28. PMID:11996072. |
in isolation, most important parameters correlated to severity included white blood cell count >18,000/mm3, lactate dehydrogenase (ldh) >400 ui/l, 10% drop of the hematocrit, serum calcium <8 mg/dl, increase of urea nitrogen >2 mg/dl, aspartate aminotransferase (ast) >200 mg/dl, ldh >600 ui/l, white blood cell count >15,000/mm3, urea >45 mg/dl, arterial ph < or = 7.33 or > or = 7.49, creatinin < or = 0.6 or > or = 1.4, hematocrit < or = 30 or > or = 45.9, white blood cell count < or = 3,000/mm3 or > or = 14,900/mm3. |
2002-05-28 |
2023-08-12 |
Not clear |
| Francesca Carubbi, Maria Eugenia Guicciardi, Mauro Concari, Paola Loria, Marco Bertolotti, Nicola Carull. Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line. Biochimica et biophysica acta. vol 1580. issue 1. 2002-05-24. PMID:11923098. |
culture media, harvested at the end of each incubation period, were analyzed to evaluate aspartate transaminase (ast), alanine transaminase and gamma-glutamyltranspeptidase release. |
2002-05-24 |
2023-08-12 |
human |
| Claudio A Redaelli, Ying-Hua Tian, Thomas Schaffner, Monika Ledermann, Hans U Baer, Jean-François Dufou. Extended preservation of rat liver graft by induction of heme oxygenase-1. Hepatology (Baltimore, Md.). vol 35. issue 5. 2002-05-24. PMID:11981758. |
preconditioning reduced serum aspartate transaminase (ast) and lactate dehydrogenase activities after reperfusion, improved bile flow, and decreased the histologic lesions of reperfusion injury. |
2002-05-24 |
2023-08-12 |
rat |
| Rudra Rai, Lucy E Wilson, Jacquie Astemborski, Frank Anania, Michael Torbenson, Charles Spoler, David Vlahov, Steffanie A Strathdee, John Boitnott, Kenrad E Nelson, David L Thoma. Severity and correlates of liver disease in hepatitis C virus-infected injection drug users. Hepatology (Baltimore, Md.). vol 35. issue 5. 2002-05-24. PMID:11981775. |
both fibrosis scores of 3 or greater and total scores of 5 or greater were associated with elevated alt, aspartate transaminase (ast), and gamma-glutamyl transpeptidase (ggt) levels (p <.01). |
2002-05-24 |
2023-08-12 |
human |
| Kenneth L Muldrew, Laura P James, Leslie Coop, Sandra S McCullough, Howard P Hendrickson, Jack A Hinson, Philip R Mayeu. Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection. Drug metabolism and disposition: the biological fate of chemicals. vol 30. issue 4. 2002-05-17. PMID:11901099. |
analysis of human serum samples for the acetaminophen-cysteine conjugate revealed a positive correlation between acetaminophen-cysteine conjugate concentration and serum aspartate aminotransferase (ast) activity or time. |
2002-05-17 |
2023-08-12 |
mouse |
| Meng-Chuan Huang, A Chao, R Kirwan, C Tschanz, J M Peralta, D A Diersen-Schade, S Cha, J T Brenn. Negligible changes in piglet serum clinical indicators or organ weights due to dietary single-cell long-chain polyunsaturated oils. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 40. issue 4. 2002-05-14. PMID:11893404. |
with litters treated as a blocked variable, no significant differences among groups were found by analysis of variance for the following serum assays: alkaline phosphatase, alanine aminotransferase (alt), aspartate aminotransferase (ast), blood urea nitrogen (bun), creatinine, albumin, glucose, cholesterol, triglycerides, and total protein. |
2002-05-14 |
2023-08-12 |
human |
| Sang K Kim, Young C Ki. Attenuation of bacterial lipopolysaccharide-induced hepatotoxicity by betaine or taurine in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 40. issue 4. 2002-05-14. PMID:11893413. |
supplementation with betaine or taurine protected the animals from induction of lps hepatotoxicity as measured by changes in aspartate aminotransferase (ast), alanine aminotransferase (alt) activities and total bilirubin levels in serum, and hepatic glutathione contents. |
2002-05-14 |
2023-08-12 |
rat |
| T Saetre, T Hovig, M Røger, Y Gundersen, A O Aase. Hepatocellular damage in porcine endotoxemia: beneficial effects of selective versus non-selective nitric oxide synthase inhibition? Scandinavian journal of clinical and laboratory investigation. vol 61. issue 7. 2002-05-09. PMID:11763408. |
lps caused significant increases in aspartate aminotransferase (ast), alkaline phosphatase (alp) and alpha glutathione s-transferase (alpha-gst), l-name caused further increases in ast, alp and alpha-gst, while ae-itu prevented the late increase in alp and alpha-gst observed in the other lps groups. |
2002-05-09 |
2023-08-12 |
Not clear |
| Rheal A Towner, Sharelle A Sturgeon, Nadeem Khan, H Hou, Harold M Swart. In vivo assessment of nodularin-induced hepatotoxicity in the rat using magnetic resonance techniques (MRI, MRS and EPR oximetry). Chemico-biological interactions. vol 139. issue 3. 2002-05-08. PMID:11879814. |
microscopic assessment (histology and electron microscopy) and serum liver enzyme function tests (aminotransferase (alt) and aspartate alt (ast)) confirmed the nodularin-induced tissue injury observed by mri. |
2002-05-08 |
2023-08-12 |
rat |
| S Sezer, B H Ozdemir, Z Arat, M Turan, N F Ozdemir, M Habera. Spectrum of liver damage and correlation with clinical and laboratory parameters in HCV infected hemodialysis patients. Renal failure. vol 23. issue 6. 2002-05-07. PMID:11777320. |
patients liver enzyme (alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma glutamyl transferase (ggt)) levels were determined monthly and ferritin levels every three months, and the mean value was recorded. |
2002-05-07 |
2023-08-12 |
Not clear |
| Sahar El-Sakka, Ezz El-Din M Salem, Mohamed S Abdel-Rahma. In vitro hepatotoxicity of alachlor and its by-products. Journal of applied toxicology : JAT. vol 22. issue 1. 2002-04-30. PMID:11807927. |
hepatocytes were harvested by a collagenase perfusion technique and were exposed to different concentrations of alachlor and its by-products for up to 2 h. cell viability, the leakage of aspartate transaminase (ast) and alanine transaminase (alt) and glutathione (gsh) depletion were determined throughout the incubation period. |
2002-04-30 |
2023-08-12 |
rat |
| Ron Palmon, Bon Chang A Koo, David A Shoultz, Douglas T Dieteric. Lack of hepatotoxicity associated with nonnucleoside reverse transcriptase inhibitors. Journal of acquired immune deficiency syndromes (1999). vol 29. issue 4. 2002-04-23. PMID:11917237. |
the overall rate of grade 3 to 4 elevations in aspartate aminotransferase (ast) or alanine aminotransferase (alt) was 3 of 272 (1.1%) and did not differ significantly among the three nnrtis. |
2002-04-23 |
2023-08-12 |
Not clear |
| Keon Wook Kang, Sung Hee Choi, Jong Ryul Ha, Choon Won Kim, Sang Geon Ki. Inhibition of dimethylnitrosamine-induced liver fibrosis by [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] (oltipraz) in rats: suppression of transforming growth factor-beta1 and tumor necrosis factor-alpha expression. Chemico-biological interactions. vol 139. issue 1. 2002-04-18. PMID:11803029. |
treatment of rats with dmn (10 microl/kg body weight, i.p., three times per week for 4 weeks) resulted in marked increases in plasma alanine aminotransferase (alt), aspartate aminotransferase (ast) and gamma-glutamyl transpeptidase (gamma-gt) activities. |
2002-04-18 |
2023-08-12 |
rat |