| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B H Ali, A K Bashir, R A Rashee. Effect of the traditional medicinal plants Rhazya stricta, Balanitis aegyptiaca and Haplophylum tuberculatum on paracetamol-induced hepatotoxicity in mice. Phytotherapy research : PTR. vol 15. issue 7. 2002-01-23. PMID:11746841. |
on the last day of treatment a hepatotoxic oral dose of paracetamol (0.6 g/kg) was given, and 3 h later, the hepatic function of mice was evaluated using pentobarbitone -induced sleeping time, the concentration of reduced glutathione (gsh) in liver, and the activities of aspartate aminotransferase (ast), alanine aminotransferase (alt), gamma-glutamyl transferase (ggt) and cholesterol concentration in plasma. |
2002-01-23 |
2023-08-12 |
mouse |
| T Arai, M Takahashi, S Kamata, T Sak. Changes in activities of enzymes related to malate-aspartate shuttle in leukocytes from dogs given a herb supplement. The Journal of veterinary medical science. vol 63. issue 6. 2002-01-15. PMID:11459021. |
activities of malate dehydrogenase (mdh) and aspartate aminotransferase (ast) in the malate-aspartate shuttle increased remarkably in mitochondria of wbc from dogs fed the herb supplementation. |
2002-01-15 |
2023-08-12 |
Not clear |
| C R Pozzi, B Corrêa, J G Xavier, G M Direito, R B Orsi, S V Matarazz. Effects of prolonged oral administration of fumonisin B1 and aflatoxin B1 in rats. Mycopathologia. vol 151. issue 1. 2002-01-14. PMID:11502059. |
rats fed with the greatest doses of afb1 and fb1 gained less weight (2.79 g/day) at the end of the experimental period; their blood concentrations of liver enzymes aspartate aminotransferase (ast) and alkaline phosphatase (ap) were above control levels (130.35 micro/l and 471.00 micro/l, respectively). |
2002-01-14 |
2023-08-12 |
rat |
| R Labib, R Turkall, M S Abdel-Rahma. Oral cocaine produces dose-related hepatotoxicity in male mice. Toxicology letters. vol 125. issue 1-3. 2001-12-20. PMID:11701220. |
serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) were measured as markers of liver injury. |
2001-12-20 |
2023-08-12 |
mouse |
| S Ishii, T Abe, T Saito, T Tsuchiya, H Kanno, M Miyazawa, M Suzuki, R Motoki, M Goto. Effects of preconditioning on ischemia/reperfusion injury of hepatocytes determined by immediate early gene transcription. Journal of hepato-biliary-pancreatic surgery. vol 8. issue 5. 2001-12-20. PMID:11702257. |
injury to hepatocytes was evaluated by measuring serum levels of aspartate transaminase (ast), alanine transaminase (alt), and lactate dehydrogenase (ldh) and that to endothelial cells by plasma concentration of hyaluronic acid (ha). |
2001-12-20 |
2023-08-12 |
rat |
| V R Akrishnan, V P Meno. Potential role of antioxidants during ethanol-induced changes in the fatty acid composition and arachidonic acid metabolites in male Wistar rats. Cell biology and toxicology. vol 17. issue 1. 2001-12-12. PMID:11504446. |
biochemical assessment of liver damage during ethanol-induced stress was done by measuring the activities of serum enzymes, viz., aspartate transaminase (ast) and alkaline phosphatase (alp), which were significantly elevated in rats fed ethanol. |
2001-12-12 |
2023-08-12 |
rat |
| H Kawagishi, Y Fukumoto, M Hatakeyama, P He, H Arimoto, T Matsuzawa, Y Arimoto, H Suganuma, T Inakuma, K Sugiyam. Liver injury suppressing compounds from avocado (Persea americana). Journal of agricultural and food chemistry. vol 49. issue 5. 2001-12-05. PMID:11368579. |
as measured by changes in the levels of plasma alanine aminotransferase (alt) and aspartate aminotransferase (ast), avocado showed extraordinarily potent liver injury suppressing activity. |
2001-12-05 |
2023-08-12 |
rat |
| D F Hwang, L C Wan. Effect of taurine on toxicity of cadmium in rats. Toxicology. vol 167. issue 3. 2001-12-04. PMID:11578796. |
the levels of cadmium in the liver and kidney, the levels of thiobarbituric acid-relative substances (tbars) in the plasma and liver, the activities of aspartate transaminase (ast) and alanine transaminase (alt) in the plasma, and the levels of blood urea nitrogen (bun) and creatinine in the plasma of rats were increased with the increasing dose of cadmium. |
2001-12-04 |
2023-08-12 |
rat |
| C A Redaelli, M Wagner, Y H Tien, L Mazzucchelli, P F Stahel, M K Schilling, J F Dufou. 1 alpha,25-Dihydroxycholecalciferol reduces rejection and improves survival in rat liver allografts. Hepatology (Baltimore, Md.). vol 34. issue 5. 2001-12-04. PMID:11679963. |
serum bilirubin, aspartate transaminase (ast), and lactate dehydrogenase (ldh) activities were significantly lower in 1,25(oh)(2)d(3)-treated animals. |
2001-12-04 |
2023-08-12 |
rat |
| D Crenesse, M Laurens, J Gugenheim, C Heurteaux, R Cursio, B Rossi, A Schmid-Allian. Intermittent ischemia reduces warm hypoxia-reoxygenation-induced JNK(1)/SAPK(1) activation and apoptosis in rat hepatocytes. Hepatology (Baltimore, Md.). vol 34. issue 5. 2001-12-04. PMID:11679968. |
serum aspartate transaminase (ast), alanine transaminase (alt), and lactate dehydrogenase levels (ldh) were measured 6 hours after ischemia. |
2001-12-04 |
2023-08-12 |
rat |
| F Fabrizi, G Lunghi, S Finazzi, P Colucci, A Pagano, C Ponticelli, F Locatell. Decreased serum aminotransferase activity in patients with chronic renal failure: impact on the detection of viral hepatitis. American journal of kidney diseases : the official journal of the National Kidney Foundation. vol 38. issue 5. 2001-12-04. PMID:11684554. |
aspartate (ast) and alanine aminotransferase (alt) activity was greater in antibody to hepatitis c (anti-hcv)-positive than anti-hcv-negative patients with crf not requiring dialysis (ast, 32.3 +/- 19 versus 18.1 +/- 8 iu/l [p = 0.0001]; alt, 32.9 +/- 28 versus 17.7 +/- 11 iu/l [p = 0.00001], respectively). |
2001-12-04 |
2023-08-12 |
Not clear |
| K Ito, H Ozasa, Y Nagashima, K Hagiwara, S Horikaw. Pharmacological preconditioning with doxorubicin. Implications of heme oxygenase-1 induction in doxorubicin-induced hepatic injury in rats. Biochemical pharmacology. vol 62. issue 9. 2001-12-04. PMID:11705458. |
when a high dose of dox (10 mg/kg body weight) was administered directly to rat liver via the portal vein, serum aspartate transaminase (ast) and alanine transaminase (alt) levels increased markedly 24 hr after the injection. |
2001-12-04 |
2023-08-12 |
human |
| S Gruttadauria, G Marino, F Catalano, A V Sgroi, G L Di Mauro, F Basil. Porcine orthotopic liver autotransplantation: facilitated technique. Journal of investigative surgery : the official journal of the Academy of Surgical Research. vol 14. issue 2. 2001-11-01. PMID:11396623. |
the cell damage was assessed in the same two groups of animals by monitoring aspartate aminotransferase (ast) and alanine aminotransferase (alt) blood levels and with the megx test, 15 min after the beginning of reperfusion. |
2001-11-01 |
2023-08-12 |
Not clear |
| G Spoto, M Fioroni, C Rubini, D Tripodi, G Perinetti, A Piattell. Aspartate aminotransferase activity in human healthy and inflamed dental pulps. Journal of endodontics. vol 27. issue 6. 2001-11-01. PMID:11487132. |
aspartate aminotransferase (ast) seems to be an important mediator of inflammatory processes. |
2001-11-01 |
2023-08-12 |
human |
| M V Santos, F R Lima, P H Rodrigues, S B Barros, L F Laranja Fonsec. Plasma ascorbate concentrations are not correlated with milk somatic cell count and metabolic profile in lactating and dry cows. Journal of dairy science. vol 84. issue 1. 2001-10-18. PMID:11210025. |
the purpose of this study was to determine the effects of stage and the number of lactation on plasma ascorbate concentration and to establish the association between plasma ascorbate concentrations and plasma glucose, insulin, nonesterified fatty acids (nefa), beta-hydroxybutyrate (bhba), aspartate aminotransferase (ast), milk somatic cell count (scc), milk yield, and body condition score (bcs) in dairy cows. |
2001-10-18 |
2023-08-12 |
Not clear |
| Q Johnson, W J Veith, T Mouto. The impact of dietary protein intake on serum biochemical and haematological profiles in vervet monkeys. Journal of medical primatology. vol 30. issue 1. 2001-10-18. PMID:11396865. |
high protein diets had no significant effect on serum biochemical indices such as aspartate aminotransferase (ast) and gamma glutamyl transferase (ggt) concentrations (p > 0.10). |
2001-10-18 |
2023-08-12 |
monkey |
| T Okamoto, H Takatsuka, Y Fujimori, H Wada, T Iwasaki, E Kakishit. Increased hepatocyte growth factor in serum in acute graft-versus-host disease. Bone marrow transplantation. vol 28. issue 2. 2001-10-11. PMID:11509938. |
furthermore, serum hgf correlated with serum concentrations of c-reactive protein, gamma-glutamyltranspeptidase (gtp), and aspartate aminotransferase (ast). |
2001-10-11 |
2023-08-12 |
Not clear |
| A C Pessini, T T Takao, E C Cavalheiro, W Vichnewski, S V Sampaio, J R Giglio, E C Arante. A hyaluronidase from Tityus serrulatus scorpion venom: isolation, characterization and inhibition by flavonoids. Toxicon : official journal of the International Society on Toxinology. vol 39. issue 10. 2001-10-04. PMID:11478957. |
this article also showed that t. serrulatus hyaluronidase affected on the activity of the venom's major toxin, tityustoxin-i (tstx-i or ts1), as reflected by alterations in the serum levels of creatine kinase (ck), lactate dehydrogenase (ld) and aspartate aminotransferase (ast) following injection of tstx-i, in the presence or absence of hyaluronidase. |
2001-10-04 |
2023-08-12 |
Not clear |
| D Z Hsu, C H Hsu, B M Huang, M Y Li. Abamectin effects on aspartate aminotransferase and nitric oxide in rats. Toxicology. vol 165. issue 2-3. 2001-10-04. PMID:11522377. |
this investigation focused on the toxicological effects of abamectin on serum aspartate aminotransferase (ast) and nitrate/nitrite (no) levels in rats. |
2001-10-04 |
2023-08-12 |
rat |
| S A Sheweita, M Abd El-Gabar, M Bastaw. Carbon tetrachloride-induced changes in the activity of phase II drug-metabolizing enzyme in the liver of male rats: role of antioxidants. Toxicology. vol 165. issue 2-3. 2001-10-04. PMID:11522380. |
in the present study, the protective effects of some antioxidants (l-ascorbic acid (aa), vitamin e (ve) or garlic) on carbon tetrachloride-induced changes in the activity of alanine amino transferase (alt), aspartate amino transferase (ast), glutathione s-transferase (gst), and the level of glutathione (gsh) and thiobarbituric acid reactive substances (tbars) were studied. |
2001-10-04 |
2023-08-12 |
rat |