| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Netopilová, R Haugvicová, H Kubová, J Drsata, P Mare. Influence of convulsants on rat brain activities of alanine aminotransferase and aspartate aminotransferase. Neurochemical research. vol 26. issue 12. 2002-09-03. PMID:11885779. |
the aim of study was to investigate if there are differences between both groups in activities of rat brain alanine aminotransferase (alt) and aspartate aminotransferase (ast), the enzymes involved in glutamate metabolism, after the administration of 3-mercaptopropionic acid as specific gad inhibitor or isoniazid as less specific general inhibitor of pyridoxal enzymes. |
2002-09-03 |
2023-08-12 |
rat |
| Niklaus P Lang, Lone Sander, Ashley Barlow, Kieran Brennan, Donald J White, Lori Bacca, Robert D Bartizek, Stephen F McClanaha. Experimental gingivitis studies: effects of triclosan and triclosan-containing dentifrices on dental plaque and gingivitis in three-week randomized controlled clinical trials. The Journal of clinical dentistry. vol 13. issue 4. 2002-09-03. PMID:12116726. |
in addition, aspartate aminotransferase activity in gingival crevicular fluid was assayed at days 0 and 21; no between-group differences were found at either of these time points, though day 21 ast activities were higher than those at baseline. |
2002-09-03 |
2023-08-12 |
human |
| Rheal A Towner, Sharelle A Sturgeon, Kristin E Hor. Assessment of in vivo oxidative lipid metabolism following acute microcystin-LR-induced hepatotoxicity in rats. Free radical research. vol 36. issue 1. 2002-08-29. PMID:11999704. |
in addition, assessment of serum enzymes alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels were used to confirm hepatotoxicity (n = 20). |
2002-08-29 |
2023-08-12 |
rat |
| P J O'Brien, Mark R Slaughter, S R Polley, K Krame. Advantages of glutamate dehydrogenase as a blood biomarker of acute hepatic injury in rats. Laboratory animals. vol 36. issue 3. 2002-08-27. PMID:12144742. |
other enzymes also evaluated were aspartate aminotransferase (ast), sorbitol dehydrogenase (sdh), and the hepatobiliary marker alkaline phosphatase (alp). |
2002-08-27 |
2023-08-12 |
human |
| Miloslava Netopilová, Jaroslav Drsata, Martin Beránek, Vladimír Palick. New potential nonsteroidal anti-inflammatory drugs with antileukotrienic effects: influence on model proteins with catalytic activity. Acta medica (Hradec Kralove). vol 45. issue 1. 2002-08-22. PMID:12143113. |
three purified enzymes were used as model proteins with catalytic activities: pig heart aspartate aminotransferase (ast, ec 2.6.1.1), alanine aminotransferase (alt, ec 2.6.1.2), and glutamate decarboxylase (gad, ec 4.1.1.15) from e. coli. |
2002-08-22 |
2023-08-12 |
Not clear |
| M G Rajesh, M S Lath. Hepatoprotection by Elephantopus scaber Linn. in CCl4-induced liver injury. Indian journal of physiology and pharmacology. vol 45. issue 4. 2002-08-16. PMID:11883157. |
in serum, liver function marker enzymes like aspartate aminotrasferase (ast), alanine aminotrasferase (alt), alkaline phosphatase (alp) and also protein were evaluated. |
2002-08-16 |
2023-08-12 |
rat |
| E Bruckert, P Giral, V Ratziu, T Poynard, M J Chapman, P Opolon, G Turpi. A constellation of cardiovascular risk factors is associated with hepatic enzyme elevation in hyperlipidemic patients. Metabolism: clinical and experimental. vol 51. issue 8. 2002-08-15. PMID:12145784. |
we analyzed the potential relationships between serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), and gamma glutamyl transferase (ggt) and cardiovascular and metabolic risk factors in a cohort of 8,501 men and women referred to our outpatient clinic for hyperlipidemia by their general practitioner. |
2002-08-15 |
2023-08-12 |
human |
| A Imaeda, T Kaneko, T Aoki, Y Kondo, H Nagas. DNA damage and the effect of antioxidants in streptozotocin-treated mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 40. issue 7. 2002-08-09. PMID:12065220. |
a single intraperitoneal injection of stz (150 mg/kg) increased serum levels of glucose, aspartate aminotransferase (ast), alanine aminotransferase (alt) and blood urea nitrogen (bun), and also caused dna damage in the liver and kidney, which recovered slowly with time. |
2002-08-09 |
2023-08-12 |
mouse |
| P N Okafor, C O Okorowkwo, E N Maduagw. Occupational and dietary exposures of humans to cyanide poisoning from large-scale cassava processing and ingestion of cassava foods. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 40. issue 7. 2002-08-09. PMID:12065222. |
an increase in plasma activity by 10% above normal of aspartate aminotransferase (ast) was observed in 40% of the cassava processors, whereas it was within normal range in all consumers. |
2002-08-09 |
2023-08-12 |
Not clear |
| Ramez Labib, Rita Turkall, Mohamed S Abdel-Rahma. Endotoxin potentiates the hepatotoxicity of cocaine in male mice. Journal of toxicology and environmental health. Part A. vol 65. issue 14. 2002-08-01. PMID:12133232. |
serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) were measured as markers of liver injury. |
2002-08-01 |
2023-08-12 |
mouse |
| M I Yousef, H A El-Hendy, F M El-Demerdash, E I Elagam. Dietary zinc deficiency induced-changes in the activity of enzymes and the levels of free radicals, lipids and protein electrophoretic behavior in growing rats. Toxicology. vol 175. issue 1-3. 2002-07-30. PMID:12049850. |
zinc deficiency increased (p<0.05) liver aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities in a dose-dependent manner, while there was no effect on the activity of these enzymes in testes. |
2002-07-30 |
2023-08-12 |
rat |
| Katherine M Conigrave, Louisa J Degenhardt, John B Whitfield, John B Saunders, Anders Helander, Boris Tabakof. CDT, GGT, and AST as markers of alcohol use: the WHO/ISBRA collaborative project. Alcoholism, clinical and experimental research. vol 26. issue 3. 2002-07-25. PMID:11923585. |
the who/isbra collaborative study allows assessment and comparison of cdt, ggt, and aspartate aminotransferase (ast) as markers of drinking in a large, well-characterized, multicenter sample. |
2002-07-25 |
2023-08-12 |
human |
| M Aksoy, A Kaya, H Vatansev, T Tekel. Testosterone secretion and semen plasma enzyme activity in rams with genital pathology stimulated with GnRH. Theriogenology. vol 57. issue 7. 2002-07-19. PMID:12041694. |
aspartate aminotransferase (ast) and lactate dehydrogenase (ldh) activity in the semen plasma varied between rams, with the lowest mean values in the bilaterally cryptorchid group (p < 0.05). |
2002-07-19 |
2023-08-12 |
Not clear |
| Hye Sook Yun-Choi, Mi Kyung Pyo, Ki Churl Chang, Duck Hyung Le. The effects of higenamine on LPS-induced experimental disseminated intravascular coagulation (DIC) in rats. Planta medica. vol 68. issue 4. 2002-07-15. PMID:11988856. |
the increase in serum aspartate aminotransferase (ast) and blood urea nitrogen (bun) were also significantly prevented with higenamine. |
2002-07-15 |
2023-08-12 |
rat |
| N K Kharchenko, V N Synyts'kyĭ, T V Kovtu. [Comparative analysis of the effects of alcoholism and opium addiction on liver function]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 47. issue 2. 2002-07-10. PMID:11392120. |
groups of patients suffering alcoholism and narcomania were examined for the effect of intoxication on the blood serum enzymes of mainly liver origin: alcohol dehydrogenase (adh), aldehyde dehydrogenase (aldh), aspartate aminotransferase (ast), alanine aminotransferase (alt), as well as on thymol test. |
2002-07-10 |
2023-08-12 |
Not clear |
| David J Marlin, Katie Fenn, Nicola Smith, Chris D Deaton, Colin A Roberts, Patricia A Harris, Christina Dunster, Frank J Kell. Changes in circulatory antioxidant status in horses during prolonged exercise. The Journal of nutrition. vol 132. issue 6 Suppl 2. 2002-07-02. PMID:12042474. |
although there were increases in creatine phosphokinase (ck), aspartate aminotransferase (ast) and tbars and a loss of tgsh, this study failed to demonstrate evidence of classical oxidative stress. |
2002-07-02 |
2023-08-12 |
Not clear |
| M Al-Mamary, M Al-Habori, A M Al-Aghbari, M M Bake. Investigation into the toxicological effects of Catha edulis leaves: a short term study in animals. Phytotherapy research : PTR. vol 16. issue 2. 2002-06-27. PMID:11933113. |
the plasma levels of aspartate aminotransferase (ast) were only moderately increased at the higher dose (30%) in the later stages of treatment. |
2002-06-27 |
2023-08-12 |
Not clear |
| Barbora Vozarova, Norbert Stefan, Robert S Lindsay, Aramesh Saremi, Richard E Pratley, Clifton Bogardus, P Antonio Tatarann. High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes. vol 51. issue 6. 2002-06-24. PMID:12031978. |
the aim of the present study was to examine whether elevated hepatic enzymes (alanine aminotransferase [alt], aspartate aminotransferase [ast], or gamma -glutamyltranspeptidase [ggt]) are associated with prospective changes in liver or whole-body insulin sensitivity and/or insulin secretion and whether these elevated enzymes predict the development of type 2 diabetes in pima indians. |
2002-06-24 |
2023-08-12 |
human |
| R Yanardağ, S Bolkent, A Kizi. Protective effects of DL-alpha-tocopherol acetate and sodium selenate on the liver of rats exposed to gamma radiation. Biological trace element research. vol 83. issue 3. 2002-06-21. PMID:11794518. |
also, the amounts of blood glutathione and serum alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), lactate dehydrogenase (ldh), and total protein were determined by spectrophotometric methods. |
2002-06-21 |
2023-08-12 |
rat |
| C Kadarian, A M Broussalis, J Miño, P Lopez, S Gorzalczany, G Ferraro, C Aceved. Hepatoprotective activity of Achyrocline satureioides(Lam) D. C. Pharmacological research. vol 45. issue 1. 2002-06-21. PMID:11820863. |
the hepatoprotective activity was evaluated in the bromobenzene- (bb-) induced hepatotoxicity model in mice through the measurement of the serum levels of alanine-aminotransferase (alt) and aspartate transaminase (ast), thiobarbituric acid reacting substances (tbars) and glutathione levels. |
2002-06-21 |
2023-08-12 |
mouse |