| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Davor Stimac, Sandra Mili\\xc4\\x87, Renata Dobrila Dintinjana, Drazen Kovac, Smiljana Risti\\xc4\\x8. Androgenic/Anabolic steroid-induced toxic hepatitis. Journal of clinical gastroenterology. vol 35. issue 4. 2002-11-26. PMID:12352300.' |
on admission, his bilirubin level was 470 micromol/l (direct, 360 micromol/l), his aspartate aminotransferase (ast) level was 5,870 iu/l, his alanine aminotransferase (alt) level was 10,580 iu/l, his alkaline phosphatase (alp) level was 152 iu/l, his gamma-glutamyl-transpeptidase level was 140 iu/l, his albumin level was 27.6 g/l, and his prothrombin time was 29%. |
2002-11-26 |
2023-08-12 |
Not clear |
| Paul S Giffen, Chris R Pick, Mark A Price, Ann Williams, Malcolm J Yor. Alpha-glutathione S-transferase in the assessment of hepatotoxicity--its diagnostic utility in comparison with other recognized markers in the Wistar Han rat. Toxicologic pathology. vol 30. issue 3. 2002-11-20. PMID:12051554. |
the diagnostic utility of alpha-glutathione s-transferase (alphagst) in the assessment of acute hepatotoxicity was compared with a range of markers including alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2002-11-20 |
2023-08-12 |
rat |
| B Zappacosta, S Persichilli, A Mordente, A Minucci, D Lazzaro, E Meucci, B Giardin. Inhibition of salivary enzymes by cigarette smoke and the protective role of glutathione. Human & experimental toxicology. vol 21. issue 1. 2002-11-14. PMID:12046726. |
in this study some salivary enzymes (lactic dehydrogenase [ldh], aspartate aminotransferase [ast] and amylase), and total gsh were measured in 20 volunteers smokers, before and just after smoking a single cigarette. |
2002-11-14 |
2023-08-12 |
human |
| Anders Larsson, Bengt Karlsso. [Modest clinical benefits of ASAT analysis in today's health care. A case report of macro-ASAT giving rise to pathologically increased ASAT levels]. Lakartidningen. vol 99. issue 38. 2002-11-14. PMID:12389251. |
aspartate aminotransferase (ast) may occur as a macroenzyme after forming a complex with immunoglobulins. |
2002-11-14 |
2023-08-12 |
Not clear |
| Yoshihito Takahashi, Raymond W Ganster, Andrea Gambotto, Lifang Shao, Takashi Kaizu, Tong Wu, Gautam P Yagnik, Atsunori Nakao, George Tsoulfas, Takashi Ishikawa, Toyokazu Okuda, David A Geller, Noriko Muras. Role of NF-kappaB on liver cold ischemia-reperfusion injury. American journal of physiology. Gastrointestinal and liver physiology. vol 283. issue 5. 2002-11-13. PMID:12381532. |
in uninfected control livers, nf-kappab was activated biphasically at 1-3 and 12 h after reperfusion with aspartate transaminase (ast) levels of 4,244 +/- 691 iu/l. |
2002-11-13 |
2023-08-12 |
rat |
| A Imaeda, T Kaneko, T Aoki, Y Kondo, N Nakamura, H Nagase, T Yoshikaw. Antioxidative effects of fluvastatin and its metabolites against DNA damage in streptozotocin-treated mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 40. issue 10. 2002-11-04. PMID:12387303. |
a single intraperitoneal injection of stz (150 mg/kg) increased serum levels of glucose, aspartate aminotransferase (ast), alanine aminotransferase (alt) and blood urea nitrogen (bun), and also caused dna damage in the liver and kidney. |
2002-11-04 |
2023-08-12 |
mouse |
| H M Levesque, T W Moon, P G C Campbell, A Hontel. Seasonal variation in carbohydrate and lipid metabolism of yellow perch (Perca flavescens) chronically exposed to metals in the field. Aquatic toxicology (Amsterdam, Netherlands). vol 60. issue 3-4. 2002-10-30. PMID:12200090. |
activities of pyruvate kinase (pyk), aspartate transaminase (ast), phosphoenolpyruvate carboxykinase (pepck) and malate dehydrogenase (mdh), were higher in fish from contaminated lakes in fall but not in summer. |
2002-10-30 |
2023-08-12 |
Not clear |
| Ramez Labib, Rita Turkall, Mohamed S Abdel-Rahma. Inhibition of cocaine oxidative metabolism attenuates endotoxin potentiation of cocaine mediated hepatotoxicity. Toxicology. vol 179. issue 1-2. 2002-10-29. PMID:12204538. |
pretreatment with skf-525a reversed the hepatic injury caused by cocaine alone or cocaine and lps treatments, as indicated by both histologic evaluation and serum alanine transaminase (alt) and aspartate transaminase (ast) activities. |
2002-10-29 |
2023-08-12 |
mouse |
| Yen-Hung Yeh, Dar-Yi Wang, Shu-Kong Chen, Jou-Fang Deng, Deng-Fwu Hwan. Effect of chenodeoxycholic acid on the toxicity of 5alpha-cyprinol sulfate in rats. Toxicology. vol 179. issue 1-2. 2002-10-29. PMID:12204539. |
after treated with 5alpha-cyprinol sulfate/chenodeoxycholic acid (9:1), 5alpha-cyprinol sulfate and chenodeoxycholic acid, the relative ratios of liver and kidney weight to body weight, the concentrations of red blood cells (rbc), hemoglobin and hematocrit in the blood, the levels of aspartate transferase (ast), alanine transferase (alt), alkaline phosphatase (alp), blood urea nitrogen (bun) and creatinine in the plasma, and the levels of bun and creatinine in the urine of rats were significantly increased, but body weight of rats and the levels of na(+), k(+), ca(++) in the urine of rats were significantly decreased, especially for both groups of 5alpha-cyprinol sulfate/chenodeoxycholic acid (9:1) and 5alpha-cyprinol sulfate. |
2002-10-29 |
2023-08-12 |
rat |
| Toru Ishidao, Naoki Kunugita, Yukiko Fueta, Keiichi Arashidani, Hajime Hor. Effects of inhaled 1-bromopropane vapor on rat metabolism. Toxicology letters. vol 134. issue 1-3. 2002-10-24. PMID:12191883. |
hepatic cytochromes p450, aspartate aminotransferase (ast) and alanine aminotransferase (alt) in blood decreased significantly with 1-bp exposure, but other enzyme activities did not differ significantly. |
2002-10-24 |
2023-08-12 |
rat |
| Fatma Cağlayan, Osman Cağlayan, Engin Gunel, Yesim Elcuman, Murat Cakma. Intestinal ischemia-reperfusion and plasma enzyme levels. Pediatric surgery international. vol 18. issue 4. 2002-10-18. PMID:12021974. |
plasma aspartate aminotransferase (ast) showed a significant increase during reperfusion while lactate dehydrogenase (ldh) and creatine kinase (ck) levels were significantly increased at the end of ischemia and continued to be so throughout reperfusion. |
2002-10-18 |
2023-08-12 |
Not clear |
| Wen-Hui Fang, Yong-Ming Yao, Zhi-Guo Shi, Yan Yu, Ye Wu, Lian-Rong Lu, Zhi-Yong Shen. The significance of changes in high mobility group-1 protein mRNA expression in rats after thermal injury. Shock (Augusta, Ga.). vol 17. issue 4. 2002-10-10. PMID:11954836. |
in addition, there were high positive correlations between hepatic hmg-1 mrna and serum aminoleucine transferase (alt) and aspartate aminotransferase (ast) levels, and also between pulmonary hmg-1 mrna and myeloperoxidase activities (p < 0.05-0.01). |
2002-10-10 |
2023-08-12 |
mouse |
| Hiroyuki Taniguchi, Eiji Yomota, Koji Nogi, Yuichi Onod. Effects of anti-ulcer agents on ethanol-induced gastric mucosal lesions in D-galactosamine-induced hepatitis rats. Arzneimittel-Forschung. vol 52. issue 8. 2002-10-01. PMID:12236047. |
subcutaneous injection of galn (1 g/kg) remarkably increased serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities suggesting induction of hepatic injury. |
2002-10-01 |
2023-08-12 |
rat |
| Melanie Beaton, Dominique Guyader, Yves Deugnier, Romain Moirand, Subrata Chakrabarti, Paul Adam. Noninvasive prediction of cirrhosis in C282Y-linked hemochromatosis. Hepatology (Baltimore, Md.). vol 36. issue 3. 2002-09-27. PMID:12198660. |
ferritin, blood platelets, and aspartate transaminase (ast) level were selected for the clinical index. |
2002-09-27 |
2023-08-12 |
Not clear |
| Olga Sánchez, Anna Arnau, Miguel Pareja, Enric Poch, Ignasi Ramírez, Maria Sole. Acute stress-induced tissue injury in mice: differences between emotional and social stress. Cell stress & chaperones. vol 7. issue 1. 2002-09-26. PMID:11892986. |
tissue injury was measured by means of the release of enzyme activities to blood plasma: lactate dehydrogenase (ldh), creatine kinase (ck), aspartate transaminase (ast), and alanine transaminase (alt). |
2002-09-26 |
2023-08-12 |
mouse |
| H Nagasawa, T Nakajima, M Yamamura, S Kaku, N Hongo. Effects of chronic treatment with caffeine on behaviour and related parameters in male and female mice. In vivo (Athens, Greece). vol 15. issue 6. 2002-09-24. PMID:11887335. |
plasma component levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), cholesterol and glucose were higher than the control in the males and females treated with 0.05% of caffeine. |
2002-09-24 |
2023-08-12 |
mouse |
| Isabelle Arnault, Yan-Ming Bao, Jean-Luc Dimicoli, Antoinette Lemoine, Mylène Sebagh, René Ada. Combined effects of fasting and alanine on liver function recovery after cold ischemia. Transplant international : official journal of the European Society for Organ Transplantation. vol 15. issue 2-3. 2002-09-24. PMID:11935165. |
the evaluation criteria were: liver weight after reperfusion, release of aspartate aminotransferase (ast), alanine aminotransferase (alt) and lactate dehydrogenase (ldh) in the perfusate, bile production, vascular resistance and liver histology after reperfusion. |
2002-09-24 |
2023-08-12 |
rat |
| N T Thuy, P He, H Takeuch. Comparative effect of dietary olive, safflower, and linseed oils on spontaneous liver tumorigenesis in C3H/He mice. Journal of nutritional science and vitaminology. vol 47. issue 5. 2002-09-10. PMID:11814153. |
in male c3h/he mice, which frequently develop spontaneous liver tumorigenesis, 5 wk of age and weighing about 20 g, the comparative effects on liver tumor incidence from the feeding of olive oil (oli), safflower oil (saf), and linseed oil (lis) diets for 50 wk, the concentrations of total cholesterol (t-chol), triacylglycerol (tg), lipid peroxides in the plasma and liver, and the activities of aspartate aminotransferase (ast) and alanine aminotransferase (alt) in the plasma were examined. |
2002-09-10 |
2023-08-12 |
mouse |
| A A Ferraz, T S Bacelar, M J Silveira, A R Coelho, R D Câmara Neto, J G de Araújo Júnior, E M Ferra. Surgical treatment of schistosomal portal hypertension. International surgery. vol 86. issue 1. 2002-09-05. PMID:11890333. |
despite the elevation on alanine aminotransferase (alt) and aspartate aminotransferase (ast), most other liver function tests showed no alteration or were corrected after surgery. |
2002-09-05 |
2023-08-12 |
Not clear |
| Dimitrios Giakoustidis, Georgios Papageorgiou, Stavros Iliadis, Nicholas Kontos, Evanthia Kostopoulou, Aikaterine Papachrestou, Dimitrios Tsantilas, Charalambos Spyridis, Dimitrios Takoudas, Nikolaos Botsoglou, Afroditi Dimitriadou, Efthymios Giakoustidi. Intramuscular administration of very high dose of alpha-tocopherol protects liver from severe ischemia/reperfusion injury. World journal of surgery. vol 26. issue 7. 2002-09-05. PMID:11960213. |
blood samples were also taken for assay of serum a-tocopherol, alanine transaminase (alt), aspartate transaminase (ast), and lactic dehydrogenase (ldh). |
2002-09-05 |
2023-08-12 |
rat |