| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M L Porceddu, O Giorgi, E Ongini, S Mele, G Biggi. 3H-SCH 23390 binding sites in the rat substantia nigra: evidence for a presynaptic localization and innervation by dopamine. Life sciences. vol 39. issue 4. 1986-09-17. PMID:3526066. |
finally, the intrastriatal injection of kainic acid produced a marked decrease of both gad activity and gaba content and 3h-sch 23390 binding sites (65%) in the homolateral substantia nigra. |
1986-09-17 |
2023-08-11 |
rat |
| A G Chapman, M J Halsey, G P Hart, N P Luff, B S Meldrum, B Wardley-Smit. Regional amino acid concentration in the brains of rats exposed to high pressures. Journal of neurochemistry. vol 47. issue 1. 1986-07-23. PMID:3711908. |
at 85 ata glutamine content increased in hippocampus, striatum, cerebellum, and substantia nigra, and gamma-aminobutyric acid content increased in hippocampus. |
1986-07-23 |
2023-08-11 |
rat |
| L Turski, E A Cavalheiro, M Schwarz, W A Turski, L E De Moraes Mello, Z A Bortolotto, T Klockgether, K H Sonta. Susceptibility to seizures produced by pilocarpine in rats after microinjection of isoniazid or gamma-vinyl-GABA into the substantia nigra. Brain research. vol 370. issue 2. 1986-06-27. PMID:3708328. |
in the present study, the effects of manipulating the activity of the gamma-aminobutyric acid (gaba)-mediated synaptic inhibition within the substantia nigra on seizures produced by pilocarpine in rats, were investigated. |
1986-06-27 |
2023-08-11 |
rat |
| A A Baumeister, G D Fry. Involvement of the midbrain reticular formation in self-injurious behavior, stereotyped behavior, and analgesia induced by intranigral microinjection of muscimol. Brain research. vol 369. issue 1-2. 1986-06-13. PMID:3008934. |
bilateral microinjection of muscimol (60 ng), a gamma-aminobutyric acid (gaba) agonist, into the central region of the substantia nigra (pars reticulata) produced self-injurious behavior (sib), stereotyped behavior and analgesic-like effects in rats. |
1986-06-13 |
2023-08-11 |
rat |
| I C Allen, A Grieve, R Griffith. Differential changes in the content of amino acid neurotransmitters in discrete regions of the rat brain prior to the onset and during the course of homocysteine-induced seizures. Journal of neurochemistry. vol 46. issue 5. 1986-05-19. PMID:2870135. |
the concentration of gamma-aminobutyric acid (gaba) decreased preictally in substantia nigra (-18%), caudate putamen (-26%), and inferior colliculus (-46%). |
1986-05-19 |
2023-08-11 |
rat |
| I C Allen, A Grieve, R Griffith. Differential changes in the content of amino acid neurotransmitters in discrete regions of the rat brain prior to the onset and during the course of homocysteine-induced seizures. Journal of neurochemistry. vol 46. issue 5. 1986-05-19. PMID:2870135. |
after seizure onset, the gaba content was further reduced in substantia nigra (-31%) and additionally in hippocampus (-18%). |
1986-05-19 |
2023-08-11 |
rat |
| T Endo, K Takazawa, S Kobayashi, T Onay. Immunochemical and immunohistochemical localization of parvalbumin in rat nervous tissues. Journal of neurochemistry. vol 46. issue 3. 1986-04-02. PMID:3512774. |
in the gamma-aminobutyric acid (gaba)-containing nuclei such as substantia nigra, caudatoputamen, and globus pallidus, parvalbumin-positive cells and fibers were rare. |
1986-04-02 |
2023-08-11 |
rat |
| A N van den Pol, A D Smith, J F Powel. GABA axons in synaptic contact with dopamine neurons in the substantia nigra: double immunocytochemistry with biotin-peroxidase and protein A-colloidal gold. Brain research. vol 348. issue 1. 1986-01-22. PMID:2866017. |
gaba axons in synaptic contact with dopamine neurons in the substantia nigra: double immunocytochemistry with biotin-peroxidase and protein a-colloidal gold. |
1986-01-22 |
2023-08-11 |
rat |
| T L Perry, M G Norman, V W Yong, S Whiting, J U Crichton, S Hansen, S J Kis. Hallervorden-Spatz disease: cysteine accumulation and cysteine dioxygenase deficiency in the globus pallidus. Annals of neurology. vol 18. issue 4. 1986-01-21. PMID:4073841. |
gamma-aminobutyric acid content was markedly decreased in the globus pallidus and substantia nigra of both patients. |
1986-01-21 |
2023-08-11 |
human |
| M S Star. Multiple opiate receptors may be involved in suppressing gamma-aminobutyrate release in substantia nigra. Life sciences. vol 37. issue 24. 1986-01-17. PMID:2999545. |
slices of rat substantia nigra were preloaded with tritiated gamma-aminobutyrate (gaba) or dopamine (da) and perfused with krebs solution containing 5 microm aminooxyacetic acid or 10 microm nialamide to inhibit the catabolism of gaba and da respectively. |
1986-01-17 |
2023-08-11 |
rat |
| M Schwarz, W Löscher, L Turski, K H Sonta. Disturbed GABAergic transmission in mutant Han-Wistar rats: further evidence for basal ganglia dysfunction. Brain research. vol 347. issue 2. 1986-01-16. PMID:2998553. |
the activity of the gaba synthesizing enzyme glutamic acid decarboxylase (gad) and the receptor binding of gaba as estimated by [3h]gaba binding to synaptic membranes were examined in olfactory bulbs, frontal cerebral cortex, corpus striatum, hippocampus, thalamus, hypothalamus, tectum, substantia nigra, medulla oblongata, cerebellum, and pons of mutant rats. |
1986-01-16 |
2023-08-11 |
rat |
| M Schwarz, W Löscher, L Turski, K H Sonta. Disturbed GABAergic transmission in mutant Han-Wistar rats: further evidence for basal ganglia dysfunction. Brain research. vol 347. issue 2. 1986-01-16. PMID:2998553. |
the changes in the activity of gad were accompanied by alterations in [3h]gaba binding to synaptic membranes: gaba binding was significantly elevated in the olfactory bulbs and the substantia nigra, but it was markedly reduced in the pons. |
1986-01-16 |
2023-08-11 |
rat |
| K Kamata, T Kameyama, S Okuyama, S Hashimoto, H Aihar. Contralateral circling behavior induced by intranigral microinjections of taurine and GABA in rats. Brain research. vol 343. issue 2. 1985-11-25. PMID:4052751. |
circling behavior induced by unilateral microinjections of taurine and gamma-aminobutyric acid (gaba) into the substantia nigra zona reticulata (snr) was studied in rats. |
1985-11-25 |
2023-08-11 |
rat |
| I Kanazawa, H Sasaki, O Muramoto, M Matsushita, T Mizutani, K Iwabuchi, T Ikeda, N Takahat. Studies on neurotransmitter markers and striatal neuronal cell density in Huntington's disease and dentatorubropallidoluysian atrophy. Journal of the neurological sciences. vol 70. issue 2. 1985-11-22. PMID:2865338. |
gaba concentration in the substantia nigra or in the globus pallidus was decreased in all "choreic" cases except one case of drpla. |
1985-11-22 |
2023-08-11 |
Not clear |
| I Kanazawa, H Sasaki, O Muramoto, M Matsushita, T Mizutani, K Iwabuchi, T Ikeda, N Takahat. Studies on neurotransmitter markers and striatal neuronal cell density in Huntington's disease and dentatorubropallidoluysian atrophy. Journal of the neurological sciences. vol 70. issue 2. 1985-11-22. PMID:2865338. |
correlation analysis of the markers in the basal ganglia and the striatal neurone densities of "choreic" patients (5 cases of hd and 3 cases of drpla) and 7 normal controls yielded positive correlation between gaba concentration in the substantia nigra and the globus pallidus, and the neuronal cell density in "small" cells in the striatum of normal control and hd. |
1985-11-22 |
2023-08-11 |
Not clear |
| C Shin, H B Pedersen, J O McNamar. gamma-Aminobutyric acid and benzodiazepine receptors in the kindling model of epilepsy: a quantitative radiohistochemical study. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 5. issue 10. 1985-11-15. PMID:2995608. |
gaba receptor binding was increased by 22% in fascia dentata of the hippocampal formation but not in neocortex or substantia nigra of kindled rats. |
1985-11-15 |
2023-08-11 |
rat |
| J M Hil. Iron concentration reduced in ventral pallidum, globus pallidus, and substantia nigra by GABA-transaminase inhibitor, gamma-vinyl GABA. Brain research. vol 342. issue 1. 1985-11-12. PMID:4041811. |
iron concentration reduced in ventral pallidum, globus pallidus, and substantia nigra by gaba-transaminase inhibitor, gamma-vinyl gaba. |
1985-11-12 |
2023-08-11 |
rat |
| J M Hil. Iron concentration reduced in ventral pallidum, globus pallidus, and substantia nigra by GABA-transaminase inhibitor, gamma-vinyl GABA. Brain research. vol 342. issue 1. 1985-11-12. PMID:4041811. |
the ventral pallidum, globus pallidus, substantia nigra and cerebellar nuclei are iron-rich areas, receive gaba-containing efferents, and have high concentrations of gamma-aminobutyric acid (gaba) and glutamic acid decarboxylase (gad). |
1985-11-12 |
2023-08-11 |
rat |
| J M Hil. Iron concentration reduced in ventral pallidum, globus pallidus, and substantia nigra by GABA-transaminase inhibitor, gamma-vinyl GABA. Brain research. vol 342. issue 1. 1985-11-12. PMID:4041811. |
gamma-vinyl gaba, an enzyme activated inhibitor of gaba-transaminase, was injected unilaterally into the globus pallidus and adjacent striatum or into the substantia nigra of the rat brain. |
1985-11-12 |
2023-08-11 |
rat |
| J M Hil. Iron concentration reduced in ventral pallidum, globus pallidus, and substantia nigra by GABA-transaminase inhibitor, gamma-vinyl GABA. Brain research. vol 342. issue 1. 1985-11-12. PMID:4041811. |
gamma-vinyl gaba injection into the striatum/pallidum resulted in a significant reduction in iron concentration in the ipsilateral ventral pallidum, globus pallidus and substantia nigra. |
1985-11-12 |
2023-08-11 |
rat |