| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Lindgren, N E Andé. Effect of the normal nerve impulse flow on the synthesis and utilization of GABA in the rat substantia nigra. Journal of neural transmission. vol 61. issue 1-2. 1985-05-03. PMID:3981161. |
the concentrations of taurine in the substantia nigra and of gaba in the corpus striatum were initially lowered and later elevated following this lesion. |
1985-05-03 |
2023-08-11 |
rat |
| S Lindgren, N E Andé. Effect of the normal nerve impulse flow on the synthesis and utilization of GABA in the rat substantia nigra. Journal of neural transmission. vol 61. issue 1-2. 1985-05-03. PMID:3981161. |
following an acute hemisection, the gaba transaminase inhibitor gamma-acetylenic gaba increased the concentration of gaba by 36% and 79% in the substantia nigra on the sectioned and intact side, respectively. |
1985-05-03 |
2023-08-11 |
rat |
| S Lindgren, N E Andé. Effect of the normal nerve impulse flow on the synthesis and utilization of GABA in the rat substantia nigra. Journal of neural transmission. vol 61. issue 1-2. 1985-05-03. PMID:3981161. |
the glutamate decarboxylase inhibitors 4-deoxypyridoxine and isoniazid lowered the concentration of gaba in the substantia nigra by about 50% on both the sectioned and intact side. |
1985-05-03 |
2023-08-11 |
rat |
| S Lindgren, N E Andé. Effect of the normal nerve impulse flow on the synthesis and utilization of GABA in the rat substantia nigra. Journal of neural transmission. vol 61. issue 1-2. 1985-05-03. PMID:3981161. |
the results indicate that the synthesis, but not the utilization of gaba in the substantia nigra is dependent on the normal nerve impulse flow. |
1985-05-03 |
2023-08-11 |
rat |
| F Nicoletti, L Grandison, J L Mee. Effects of repeated administration of estradiol benzoate on tubero-infundibular GABAergic activity in male rats. Journal of neurochemistry. vol 44. issue 4. 1985-04-24. PMID:3973612. |
gaba concentration also increased in the median eminence whereas no changes or decreases were observed in other brain regions including hypothalamic arcuate nucleus, lateral septum, hippocampus, caudate nucleus, and substantia nigra. |
1985-04-24 |
2023-08-11 |
rat |
| J Kornhuber, J S Kim, M E Kornhuber, H H Kornhube. The cortico-nigral projection: reduced glutamate content in the substantia nigra following frontal cortex ablation in the rat. Brain research. vol 322. issue 1. 1985-03-07. PMID:6151416. |
the gaba level in the substantia nigra and both the glutamate and gaba levels in the hippocampus remain unchanged. |
1985-03-07 |
2023-08-12 |
rat |
| R D Pinnoc. Hyperpolarizing action of baclofen on neurons in the rat substantia nigra slice. Brain research. vol 322. issue 2. 1985-02-11. PMID:6509322. |
gaba, muscimol and l-baclofen inhibited zona compacta neurons in the rat substantia nigra slice, d-baclofen was inactive, l-baclofen produced a potent hyperpolarization of the membrane potential. |
1985-02-11 |
2023-08-12 |
rat |
| B L Waszczak, J R Walter. A physiological role for dopamine as modulator of GABA effects in substantia nigra: supersensitivity in 6-hydroxydopamine-lesioned rats. European journal of pharmacology. vol 105. issue 3-4. 1985-02-04. PMID:6439567. |
a physiological role for dopamine as modulator of gaba effects in substantia nigra: supersensitivity in 6-hydroxydopamine-lesioned rats. |
1985-02-04 |
2023-08-12 |
rat |
| M Araki, P L McGeer, E G McGee. Presumptive gamma-aminobutyric acid pathways from the midbrain to the superior colliculus studied by a combined horseradish peroxidase-gamma-aminobutyric acid transaminase pharmacohistochemical method. Neuroscience. vol 13. issue 2. 1985-01-31. PMID:6096762. |
the results indicate projections from the substantia nigra zona reticulata, the zona incerta and the reticular formation of the mesencephalon which are exclusively from neurons staining intensely for gamma-aminobutyric acid transaminase and presumptively gamma-aminobutyric acid as their transmitter. |
1985-01-31 |
2023-08-12 |
Not clear |
| J Glowinski, M J Besson, A Chéram. Role of the thalamus in the bilateral regulation of dopaminergic and GABAergic neurons in the basal ganglia. Ciba Foundation symposium. vol 107. 1985-01-24. PMID:6094123. |
the role of thalamic nuclei in the bilateral regulation of dopamine and gaba release in the caudate nucleus and substantia nigra is further demonstrated by studies showing that (1) electrical stimulation of thalamic motor nuclei induces bilateral asymmetrical changes in dopamine release resembling the changes evoked by unilateral sensory stimuli or stimulation of cerebellar nuclei; (2) electrical stimulation of intralaminar or some midline thalamic nuclei leads to bilateral (or contralateral) symmetrical changes in dopamine release, some of these effects being comparable to those induced by unilateral stimulation of the motor cortex; (3) unilateral lesions of motor or intralaminar thalamic nuclei reverse the changes in gaba release in the contralateral caudate nucleus or substantia nigra induced by unilateral infusion of muscimol into the nigra; and (4) unilateral infusion of gaba into thalamic motor nuclei induces bilateral symmetrical regulation of dopamine release in caudate nuclei by means of presynaptic facilitatory influences. |
1985-01-24 |
2023-08-12 |
Not clear |
| C Reavill, P Jenner, C D Marsde. Gamma-aminobutyric acid and basal ganglia outflow pathways. Ciba Foundation symposium. vol 107. 1985-01-24. PMID:6094124. |
neurons containing gamma-aminobutyric acid (gaba) are important outflow pathways from the striatum to the pallidal complex and substantia nigra. |
1985-01-24 |
2023-08-12 |
rat |
| J Kornhuber, J S Kim, M E Kornhuber, H H Kornhube. Chronic haloperidol administration enhances the gamma-aminobutyric acid level in the rat striatum without altering the glutamate level. European neurology. vol 23. issue 4. 1984-12-20. PMID:6541578. |
the unaltered gaba level in the substantia nigra is compatible with the existence of gabaergic interneurons in the striatum, which are inhibited by the afferent dopaminergic innervation to the striatum. |
1984-12-20 |
2023-08-12 |
rat |
| S M Lasley, R D Greenland, I A Michaelso. Determination of gamma-aminobutyric and glutamic acids in rat brain by liquid chromatography with electrochemical detection. Life sciences. vol 35. issue 19. 1984-12-05. PMID:6149441. |
significant increases in gamma-aminobutyric acid content in nucleus accumbens and substantia nigra could be detected 20 minutes after injection of 400 mg/kg valproic acid. |
1984-12-05 |
2023-08-12 |
rat |
| R Romo, A Chéramy, G Godeheu, J Glowinsk. Distinct commissural pathways are involved in the enhanced release of dopamine induced in the contralateral caudate nucleus and substantia nigra by unilateral application of GABA in the cat thalamic motor nuclei. Brain research. vol 308. issue 1. 1984-11-14. PMID:6383515. |
distinct commissural pathways are involved in the enhanced release of dopamine induced in the contralateral caudate nucleus and substantia nigra by unilateral application of gaba in the cat thalamic motor nuclei. |
1984-11-14 |
2023-08-12 |
cat |
| R Romo, A Chéramy, G Godeheu, J Glowinsk. Distinct commissural pathways are involved in the enhanced release of dopamine induced in the contralateral caudate nucleus and substantia nigra by unilateral application of GABA in the cat thalamic motor nuclei. Brain research. vol 308. issue 1. 1984-11-14. PMID:6383515. |
the effects of diencephalic or telencephalic commissural sectioning on the changes in [3h]dopamine ([3h]da) release from nerve terminals (in the caudate nucleus, cn) and dendrites (in the substantia nigra, sn) of the two nigro-striatal dopaminergic pathways induced by the application of gaba (10(-5) m, 30 min) into the left ventralis medialis (vm) or ventralis lateralis (vl) thalamic nuclei were investigated. |
1984-11-14 |
2023-08-12 |
cat |
| M Schwarz, K H Sontag, P Wan. Non-dopaminergic neurones of the reticular part of substantia nigra can gate static fusimotor action onto flexors in cat. The Journal of physiology. vol 354. 1984-11-13. PMID:6090651. |
the effect on the fusimotor system of electrical stimulation of the reticular part of the substantia nigra or of the injection of the gamma-aminobutyric acid (gaba)-antagonist picrotoxin into this structure was studied in spindle receptors of pretibial flexors in cats anaesthetized with ketamine. |
1984-11-13 |
2023-08-12 |
cat |
| J O McNamara, M T Galloway, L C Rigsbee, C Shi. Evidence implicating substantia nigra in regulation of kindled seizure threshold. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 4. issue 9. 1984-11-06. PMID:6481454. |
bilateral microinjection of a gamma-aminobutyric acid (gaba) agonist, muscimol, into the area of the substantia nigra (sn) markedly suppressed both motor and limbic seizures induced by stimulation of amygdala, olfactory structures, or lateral entorhinal cortex. |
1984-11-06 |
2023-08-12 |
Not clear |
| C Reavill, S Muscatt, P N Leigh, P Jenner, C D Marsde. Enhanced GABA function in the angular complex (lateral periaqueductal grey matter and adjacent reticular formation) alters the postural component of striatal- or nigral-derived circling. Experimental brain research. vol 56. issue 1. 1984-10-19. PMID:6468558. |
manipulation of gaba function in the angular complex alters circling behaviour initiated from the striatum or substantia nigra by altering the postural component without affecting the locomotor response of the animals. |
1984-10-19 |
2023-08-12 |
Not clear |
| G R Breese, G D Frye, T J McCown, R A Muelle. Comparison of the CNS effects induced by TRH and bicuculline after microinjection into medial septum, substantia nigra and inferior colliculus: absence of support for a GABA antagonist action for TRH. Pharmacology, biochemistry, and behavior. vol 21. issue 1. 1984-09-19. PMID:6431450. |
comparison of the cns effects induced by trh and bicuculline after microinjection into medial septum, substantia nigra and inferior colliculus: absence of support for a gaba antagonist action for trh. |
1984-09-19 |
2023-08-12 |
Not clear |
| A A Baumeister, G D Fry. Self-injurious behavior in rats produced by intranigral microinjection of GABA agonists. Pharmacology, biochemistry, and behavior. vol 21. issue 1. 1984-09-19. PMID:6540454. |
bilateral injection of the gaba agonist muscimol (10-300 ng) into the caudal substantia nigra (pars reticulata) of rats produced dose-dependent stereotyped gnawing and self-biting. |
1984-09-19 |
2023-08-12 |
rat |