| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T L Perry, S Hansen, K Jone. Brain amino acids and glutathione in progressive supranuclear palsy. Neurology. vol 38. issue 6. 1988-06-17. PMID:3368077. |
in psp, we found glutamic acid markedly increased in the nucleus accumbens; taurine significantly increased in nucleus accumbens, substantia nigra, and globus pallidus; and gamma-aminobutyric acid significantly increased in nucleus accumbens and putamen. |
1988-06-17 |
2023-08-11 |
human |
| I Kanazawa, S Kwak, H Sasaki, O Muramoto, T Mizutani, A Hori, N Nukin. Studies on neurotransmitter markers of the basal ganglia in Pick's disease, with special reference to dopamine reduction. Journal of the neurological sciences. vol 83. issue 1. 1988-04-12. PMID:2450180. |
gaba and substance p levels in the substantia nigra and the globus pallidus were generally decreased, corresponding to the moderate to severe loss of small neurones in the striatum. |
1988-04-12 |
2023-08-11 |
Not clear |
| B C Robertson, D W Hommer, L R Skirbol. Electrophysiological evidence for a non-opioid interaction between dynorphin and GABA in the substantia nigra of the rat. Neuroscience. vol 23. issue 2. 1988-03-28. PMID:2893989. |
electrophysiological evidence for a non-opioid interaction between dynorphin and gaba in the substantia nigra of the rat. |
1988-03-28 |
2023-08-11 |
rat |
| B C Robertson, D W Hommer, L R Skirbol. Electrophysiological evidence for a non-opioid interaction between dynorphin and GABA in the substantia nigra of the rat. Neuroscience. vol 23. issue 2. 1988-03-28. PMID:2893989. |
interactions between neuronal responses mediated by dynorphin a1-8 and gaba were investigated in the substantia nigra zona reticulata. |
1988-03-28 |
2023-08-11 |
rat |
| B C Robertson, D W Hommer, L R Skirbol. Electrophysiological evidence for a non-opioid interaction between dynorphin and GABA in the substantia nigra of the rat. Neuroscience. vol 23. issue 2. 1988-03-28. PMID:2893989. |
the role of dynorphin in the basal ganglia and its interaction with the other major transmitter in the substantia nigra zona reticulata, gaba, is discussed. |
1988-03-28 |
2023-08-11 |
rat |
| D W Ellison, M F Beal, M F Mazurek, J R Malloy, E D Bird, J B Marti. Amino acid neurotransmitter abnormalities in Huntington's disease and the quinolinic acid animal model of Huntington's disease. Brain : a journal of neurology. vol 110 ( Pt 6). 1988-03-07. PMID:2892568. |
gaba reductions were found in both segments of the globus pallidus (external greater than internal) and both parts of the substantia nigra (reticulata greater than compacta). |
1988-03-07 |
2023-08-11 |
rat |
| J M Frey, M K Ticku, R D Huffma. GABAergic supersensitivity within the pars reticulata of the rat substantia nigra following chronic haloperidol administration. Brain research. vol 425. issue 1. 1988-02-26. PMID:3427428. |
these studies were performed to evaluate the effects of chronic haloperidol administration on the responsiveness of the pars reticulata neurons of the substantia nigra (snr) to microiontophoretically applied gamma-aminobutyric acid (gaba) and glycine. |
1988-02-26 |
2023-08-11 |
rat |
| b' H Manev, D Perici\\xc4\\x8. Sex difference in the turnover of GABA in the rat substantia nigra. Journal of neural transmission. vol 70. issue 3-4. 1988-01-20. PMID:3681288.' |
sex difference in the turnover of gaba in the rat substantia nigra. |
1988-01-20 |
2023-08-11 |
rat |
| b' H Manev, D Perici\\xc4\\x8. Sex difference in the turnover of GABA in the rat substantia nigra. Journal of neural transmission. vol 70. issue 3-4. 1988-01-20. PMID:3681288.' |
the turnover of gaba (estimated from the post-mortem accumulation of gaba), and the activity of glutamic acid decarboxylase and gaba transaminase, along with the saturation of both enzymes by cofactor pyridoxal phosphate, were studied in the substantia nigra of rats of both sexes. |
1988-01-20 |
2023-08-11 |
rat |
| C Gauchy, M L Kemel, M Desban, R Romo, J Glowinski, M J Besso. The role of dopamine released from distal and proximal dendrites of nigrostriatal dopaminergic neurons in the control of GABA transmission in the thalamic nucleus ventralis medialis in the cat. Neuroscience. vol 22. issue 3. 1988-01-20. PMID:3683856. |
therefore, the decreased release of [3h]gaba in the nucleus ventralis medialis seen following application of amphetamine in the pars reticulata of the substantia nigra could result from an inhibition of nigrothalamic gabaergic neurons. |
1988-01-20 |
2023-08-11 |
cat |
| C Gauchy, M L Kemel, M Desban, R Romo, J Glowinski, M J Besso. The role of dopamine released from distal and proximal dendrites of nigrostriatal dopaminergic neurons in the control of GABA transmission in the thalamic nucleus ventralis medialis in the cat. Neuroscience. vol 22. issue 3. 1988-01-20. PMID:3683856. |
these results suggested that the increased release of [3h]gaba seen in the nucleus ventralis medialis following application of amphetamine in the pars compacta of the substantia nigra might be linked to the enhanced firing rate of entopeduncular-thalamic gabaergic neurons. |
1988-01-20 |
2023-08-11 |
cat |
| K Semba, H C Fibiger, S R Vincen. Neurotransmitters in the mammalian striatum: neuronal circuits and heterogeneity. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 14. issue 3 Suppl. 1988-01-13. PMID:2445456. |
the major output neurons have been identified as medium spiny neurons which contain gamma-aminobutyric acid (gaba), endogeneous opioids, and substance p. these neurons project to the pallidum and substantia nigra in a topographic and probably chemically organized manner. |
1988-01-13 |
2023-08-11 |
Not clear |
| M Guttma. Receptors in the basal ganglia. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 14. issue 3 Suppl. 1988-01-13. PMID:2824009. |
in the substantia nigra (sn), receptors have been identified for somatostatin, neurotensin, substance p, glycine, benzodiazepine and gaba, opiates, dopamine, angiotensin converting enzyme (ace) and serotonin. |
1988-01-13 |
2023-08-11 |
Not clear |
| W Löscher, W S Schwar. Further evidence for abnormal GABAergic circuits in amygdala-kindled rats. Brain research. vol 420. issue 2. 1987-12-22. PMID:2823978. |
compared to controls, gaba synthesis was reduced in the ipsilateral (stimulated) amygdala and in corpus striatum and substantia nigra. |
1987-12-22 |
2023-08-11 |
rat |
| W Löscher, W S Schwar. Further evidence for abnormal GABAergic circuits in amygdala-kindled rats. Brain research. vol 420. issue 2. 1987-12-22. PMID:2823978. |
gaba receptor binding was decreased in amygdala and substantia nigra but significantly increased in the striatum. |
1987-12-22 |
2023-08-11 |
rat |
| U K Rinne, J O Rinne, J K Rinne, K Laaks. Chemical neurotransmission in the parkinsonian brain. Medical biology. vol 65. issue 2-3. 1987-11-19. PMID:2821331. |
the decreased gaba receptor binding in the parkinsonian substantia nigra possibly reflects the loss of nigral dopamine neurons, since nigral gaba receptors are located on these neurons. |
1987-11-19 |
2023-08-11 |
Not clear |
| M Star. Opposing roles of dopamine D1 and D2 receptors in nigral gamma-[3H]aminobutyric acid release? Journal of neurochemistry. vol 49. issue 4. 1987-10-19. PMID:2957468. |
this study examined the effects of dopamine d1 and d2 receptor agonists and antagonists on the spontaneous and calcium-dependent, k+-induced release of gamma-[3h]aminobutyric acid [( 3h]gaba) accumulated by slices of rat substantia nigra. |
1987-10-19 |
2023-08-11 |
rat |
| H R Toussi, R A Schatz, B L Waszcza. Suppression of methionine sulfoximine seizures by intranigral gamma-vinyl GABA injection. European journal of pharmacology. vol 137. issue 2-3. 1987-09-24. PMID:3609144. |
these results further support the hypothesis that elevation of cerebral gaba levels is protective against a range of experimentally induced seizures, particularly when the substantia nigra is the target of such manipulations. |
1987-09-24 |
2023-08-11 |
Not clear |
| N E Andén, S Lindgren, A Magnusso. Regional differences in the changes in rat brain GABA concentrations post mortem and following inhibition of the synthesis and metabolism. Pharmacology & toxicology. vol 60. issue 5. 1987-09-22. PMID:3615349. |
experimentally induced changes in the concentration of gaba were studied in regions where gaba is present, predominantly in nerve terminals (substantia nigra, pituitary gland) or outside nerve terminals (corpus callosum). |
1987-09-22 |
2023-08-11 |
rat |
| N E Andén, S Lindgren, A Magnusso. Regional differences in the changes in rat brain GABA concentrations post mortem and following inhibition of the synthesis and metabolism. Pharmacology & toxicology. vol 60. issue 5. 1987-09-22. PMID:3615349. |
the glutamic acid decarboxylase inhibitor 4-deoxypyridoxine decreased the endogenous concentration of gaba and it inhibited the increase in gaba induced by gamma-acetylenic gaba in the substantia nigra and in the pituitary gland, but not in the corpus callosum, indicating that this compound inhibits the decarboxylase mainly in the gaba nerve terminals. |
1987-09-22 |
2023-08-11 |
rat |