| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jason R Cannon, J Timothy Greenamyr. NeuN is not a reliable marker of dopamine neurons in rat substantia nigra. Neuroscience letters. vol 464. issue 1. 2009-11-03. PMID:19682546. |
neun is not a reliable marker of dopamine neurons in rat substantia nigra. |
2009-11-03 |
2023-08-12 |
rat |
| Rui D S Prediger, Daniel Rial, Rodrigo Medeiros, Cláudia P Figueiredo, Richard L Doty, Reinaldo N Takahash. Risk is in the air: an intranasal MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) rat model of Parkinson's disease. Annals of the New York Academy of Sciences. vol 1170. 2009-09-25. PMID:19686204. |
such infusion decreased the expression of the enzyme tyrosine hydroxylase in the olfactory bulb and substantia nigra by means of apoptotic mechanisms, reducing dopamine levels in different brain structures, such as the olfactory bulb, striatum, and prefrontal cortex. |
2009-09-25 |
2023-08-12 |
rat |
| Seema Singh, Kavita Singh, Devendra Kumar Patel, Chetna Singh, Chandishwar Nath, Vinod Kumar Singh, Raj Kumar Singh, Mahendra Pratap Sing. The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection. Rejuvenation research. vol 12. issue 3. 2009-09-22. PMID:19594327. |
tyrosine hydroxylase (th)-immunoreactivity in the substantia nigra, the expression of nicotinic acetylcholine receptors (nachrs) alpha6 and alpha4, dopamine content, and 1-methyl-4-phenylpyridinium ion (mpp(+)) level in the striatum were measured to confirm the mptp-induced pd phenotype and nicotine-mediated neuroprotection. |
2009-09-22 |
2023-08-12 |
mouse |
| E Lagrue, B Abert, L Nadal, L Tabone, S Bodard, F Medja, A Lombes, S Chalon, P Castelna. MPTP intoxication in mice: a useful model of Leigh syndrome to study mitochondrial diseases in childhood. Metabolic brain disease. vol 24. issue 2. 2009-09-14. PMID:19319673. |
th immunoreactivity was reduced in the striatum and substantia nigra (p = 0.005), and striatal dopamine was significantly reduced (p < 0.01). |
2009-09-14 |
2023-08-12 |
mouse |
| Shelly Arreguin, Paul Nelson, Shelby Padway, Matthew Shirazi, Cortlandt Pierpon. Dopamine complexes of iron in the etiology and pathogenesis of Parkinson's disease. Journal of inorganic biochemistry. vol 103. issue 1. 2009-09-09. PMID:18976814. |
much of the neuronal damage takes place in the substantia nigra, a small region of the midbrain that contains the cell bodies of neurons that produce dopamine. |
2009-09-09 |
2023-08-12 |
Not clear |
| Filip Simunovic, Ming Yi, Yulei Wang, Laurel Macey, Lauren T Brown, Anna M Krichevsky, Susan L Andersen, Robert M Stephens, Francine M Benes, Kai C Sonnta. Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology. Brain : a journal of neurology. vol 132. issue Pt 7. 2009-09-09. PMID:19052140. |
gene expression profiling of substantia nigra dopamine neurons: further insights into parkinson's disease pathology. |
2009-09-09 |
2023-08-12 |
human |
| Tinmarla F Oo, Deanna M Marchionini, Olga Yarygina, Paul D O'Leary, Richard A Hughes, Nikolai Kholodilov, Robert E Burk. Brain-derived neurotrophic factor regulates early postnatal developmental cell death of dopamine neurons of the substantia nigra in vivo. Molecular and cellular neurosciences. vol 41. issue 4. 2009-09-07. PMID:19409492. |
brain-derived neurotrophic factor regulates early postnatal developmental cell death of dopamine neurons of the substantia nigra in vivo. |
2009-09-07 |
2023-08-12 |
mouse |
| Hansruedi Büele. Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease. Experimental neurology. vol 218. issue 2. 2009-09-04. PMID:19303005. |
accumulation of clonal, somatic mitochondrial dna deletions has been observed in the substantia nigra during aging and in pd, suggesting that mitochondrial dna mutations in some instances may pre-dispose to dopamine neuron death by impairing respiration. |
2009-09-04 |
2023-08-12 |
Not clear |
| Mark Obermann, M Küper, O Kastrup, O Yaldizli, S Esser, J Thiermann, E Koutsilieri, G Arendt, H-C Diener, M Maschk. Substantia nigra hyperechogenicity and CSF dopamine depletion in HIV. Journal of neurology. vol 256. issue 6. 2009-09-02. PMID:19240951. |
substantia nigra hyperechogenicity and csf dopamine depletion in hiv. |
2009-09-02 |
2023-08-12 |
human |
| Mark Obermann, M Küper, O Kastrup, O Yaldizli, S Esser, J Thiermann, E Koutsilieri, G Arendt, H-C Diener, M Maschk. Substantia nigra hyperechogenicity and CSF dopamine depletion in HIV. Journal of neurology. vol 256. issue 6. 2009-09-02. PMID:19240951. |
decreased dopamine (da) levels in the cerebrospinal fluid (csf) and neuronal loss in the substantia nigra (sn) have been reported in hiv-infected patients, suggesting nigrostriatal damage. |
2009-09-02 |
2023-08-12 |
human |
| Emrah Düzel, Nico Bunzeck, Marc Guitart-Masip, Bianca Wittmann, Bjoern H Schott, Philippe N Toble. Functional imaging of the human dopaminergic midbrain. Trends in neurosciences. vol 32. issue 6. 2009-09-01. PMID:19446348. |
invasive recording of dopamine neurons in the substantia nigra and ventral tegmental area (sn/vta) of behaving animals suggests a role for these neurons in reward learning and novelty processing. |
2009-09-01 |
2023-08-12 |
human |
| Vincent Ries, Hsiao-Chun Cheng, Amy Baohan, Tatyana Kareva, Tinmarla F Oo, Margarita Rzhetskaya, Ross J Bland, Matthew J During, Nikolai Kholodilov, Robert E Burk. Regulation of the postnatal development of dopamine neurons of the substantia nigra in vivo by Akt/protein kinase B. Journal of neurochemistry. vol 110. issue 1. 2009-08-21. PMID:19490361. |
regulation of the postnatal development of dopamine neurons of the substantia nigra in vivo by akt/protein kinase b. |
2009-08-21 |
2023-08-12 |
Not clear |
| Jeffrey B Eells, Timothy Brow. Repeated developmental exposure to chlorpyrifos and methyl parathion causes persistent alterations in nicotinic acetylcholine subunit mRNA expression with chlorpyrifos altering dopamine metabolite levels. Neurotoxicology and teratology. vol 31. issue 2. 2009-08-20. PMID:18977431. |
levels of dopamine and its metabolites 3,4 dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva) were measured in the striatum and mrna expression was measured in the substantia nigra. |
2009-08-20 |
2023-08-12 |
rat |
| Robert M Kessler, Neil D Woodward, Patrizia Riccardi, Rui Li, M Sib Ansari, Sharlett Anderson, Benoit Dawant, David Zald, Herbert Y Meltze. Dopamine D2 receptor levels in striatum, thalamus, substantia nigra, limbic regions, and cortex in schizophrenic subjects. Biological psychiatry. vol 65. issue 12. 2009-08-20. PMID:19251247. |
dopamine d2 receptor levels in striatum, thalamus, substantia nigra, limbic regions, and cortex in schizophrenic subjects. |
2009-08-20 |
2023-08-12 |
human |
| Giuseppe Di Giovanni, Wei-Xing Sh. Effects of scopolamine on dopamine neurons in the substantia nigra: role of the pedunculopontine tegmental nucleus. Synapse (New York, N.Y.). vol 63. issue 8. 2009-08-19. PMID:19360852. |
effects of scopolamine on dopamine neurons in the substantia nigra: role of the pedunculopontine tegmental nucleus. |
2009-08-19 |
2023-08-12 |
Not clear |
| H Niazi Shahabi, L Westberg, J Melke, A Håkansson, A Carmine Belin, O Sydow, L Olson, B Holmberg, H Nissbrand. Cytochrome P450 2E1 gene polymorphisms/haplotypes and Parkinson's disease in a Swedish population. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 5. 2009-08-14. PMID:19381774. |
cytochrome p450 2e1 (cyp2e1), which inter alia is located in dopamine containing neurons in the substantia nigra, has been hypothesized to be of importance for the pathophysiology of parkinson's disease (pd), either by its production of reactive oxygen species (ros) or by its capability to detoxify putative neurotoxins. |
2009-08-14 |
2023-08-12 |
Not clear |
| Néstor F Díaz, Néstor E Díaz-Martínez, Ignacio Camacho-Arroyo, Iván Velasc. Estradiol promotes proliferation of dopaminergic precursors resulting in a higher proportion of dopamine neurons derived from mouse embryonic stem cells. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 27. issue 5. 2009-08-12. PMID:19379802. |
estradiol protects dopamine neurons of the substantia nigra from toxic insults. |
2009-08-12 |
2023-08-12 |
mouse |
| Yingjun Zheng, Akiya Watakabe, Masahiko Takada, Akiyoshi Kakita, Hisaaki Namba, Hitoshi Takahashi, Tetsuo Yamamori, Hiroyuki Naw. Expression of ErbB4 in substantia nigra dopamine neurons of monkeys and humans. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 4. 2009-08-10. PMID:19336245. |
expression of erbb4 in substantia nigra dopamine neurons of monkeys and humans. |
2009-08-10 |
2023-08-12 |
human |
| Yingjun Zheng, Akiya Watakabe, Masahiko Takada, Akiyoshi Kakita, Hisaaki Namba, Hitoshi Takahashi, Tetsuo Yamamori, Hiroyuki Naw. Expression of ErbB4 in substantia nigra dopamine neurons of monkeys and humans. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 4. 2009-08-10. PMID:19336245. |
to assess the role of neuregulin-1 in the dopamine hypothesis of schizophrenia, we used in situ hybridization and immunoblotting to investigate the cellular distribution of erbb4 mrna in the substantia nigra of japanese monkeys (macaca fuscata) and human postmortem brains. |
2009-08-10 |
2023-08-12 |
human |
| Yingjun Zheng, Akiya Watakabe, Masahiko Takada, Akiyoshi Kakita, Hisaaki Namba, Hitoshi Takahashi, Tetsuo Yamamori, Hiroyuki Naw. Expression of ErbB4 in substantia nigra dopamine neurons of monkeys and humans. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 4. 2009-08-10. PMID:19336245. |
in both monkeys and humans, significant signal for erbb4 mrna was detected in substantia nigra dopamine neurons, which were identified by melanin deposits. |
2009-08-10 |
2023-08-12 |
human |