| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Annelie Handreck, Bianca Backofen-Wehrhahn, Sonja Bröer, Wolfgang Löscher, Manuela Gerner. Anticonvulsant effects by bilateral and unilateral transplantation of GABA-producing cells into the subthalamic nucleus in an acute seizure model. Cell transplantation. vol 23. issue 1. 2014-10-30. PMID:23191981. |
we observed (a) that grafted cells survived up to the end of the experiments, (b) that anticonvulsant effects can be induced by bilateral transplantation into the stn using immortalized gabaergic cells derived from the rat embryonic striatum and cells additionally transfected to obtain higher gaba synthesis than the parent cell line, and (c) that anticonvulsant effects were observed even after unilateral transplantation into the stn. |
2014-10-30 |
2023-08-12 |
rat |
| Xianrong Zhang, Junfang Wu, Huilang Liu, Xu Zhan. Age- and gender-related metabonomic alterations in striatum and cerebellar cortex in rats. Brain research. vol 1507. 2014-09-18. PMID:23454230. |
old female rats had decreased glutamate and increased creatine in striatum, while old male rats had increased choline in striatum, and increased gaba in cerebellar cortex, respectively. |
2014-09-18 |
2023-08-12 |
rat |
| Kevin W McCairn, Masaki Isod. Pharmacological animal models of tic disorders. International review of neurobiology. vol 112. 2014-07-14. PMID:24295622. |
among a variety of pharmacological models, focal microinjection of gaba antagonists into the sensorimotor striatum has helped identify abnormal neural discharge in the global networks which underlie tourettism, including not only the cerebral cortex and basal ganglia but also the cerebellum, consistent with recent neuroimaging studies for ts subjects. |
2014-07-14 |
2023-08-12 |
human |
| Andrew P Mayer, Ivan Osorio, Craig E Lunt. Microperfusion of 3-MPA into the brain augments GABA. Epilepsy & behavior : E&B. vol 29. issue 3. 2014-07-03. PMID:24094842. |
in vivo effects of microperfusion of a gaba synthesis inhibitor (3-mpa) into the striatum and hippocampus on amino acid concentrations and electrical neuronal activity were investigated. |
2014-07-03 |
2023-08-12 |
rat |
| Andrew P Mayer, Ivan Osorio, Craig E Lunt. Microperfusion of 3-MPA into the brain augments GABA. Epilepsy & behavior : E&B. vol 29. issue 3. 2014-07-03. PMID:24094842. |
paradoxical elevations in gaba in the striatum (5-fold in anesthetized and 50-fold in awake rats) and hippocampus (2-fold in anesthetized and 15-fold in awake rats) were documented under steady-state concentrations of 3-mpa along with expected increases in glutamate (a 15-fold increase and a 250-fold increase in the striatum of anesthetized and awake rats, respectively; a 7-fold increase and a 25-fold increase in the hippocampus of anesthetized and awake rats, respectively). |
2014-07-03 |
2023-08-12 |
rat |
| Masanori Otsuk. Contributions to the field of neurotransmitters by Japanese scientists, and reflections on my own research. Proceedings of the Japan Academy. Series B, Physical and biological sciences. vol 83. issue 2. 2014-06-24. PMID:24019584. |
part i describes important contributions made by some japanese pioneers in the field of neurotransmitters: (their achievements in parentheses) j. takamine (isolation and crystallization of adrenaline); k. shimidzu (early hint for acetylcholine as a neurotransmitter); f. kanematsu (donation of the kanematsu memorial institute in sydney); t. hayashi (discovery of the excitatory action of glutamate and the inhibitory action of gaba); and i. sano (discovery of a high concentration of dopamine in striatum, its reduction in a patient with parkinson's disease and the treatment with dopa). |
2014-06-24 |
2023-08-12 |
Not clear |
| R N Kalaria, A K Princ. Effects of thyroid deficiency on the development of cholinergic, GABA, dopaminergic and glutamate neuron markers and DNA concentrations in the rat corpus striatum. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 3. issue 6. 2014-06-02. PMID:24875111. |
effects of thyroid deficiency on the development of cholinergic, gaba, dopaminergic and glutamate neuron markers and dna concentrations in the rat corpus striatum. |
2014-06-02 |
2023-08-13 |
rat |
| R N Kalaria, A K Princ. Effects of thyroid deficiency on the development of cholinergic, GABA, dopaminergic and glutamate neuron markers and DNA concentrations in the rat corpus striatum. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 3. issue 6. 2014-06-02. PMID:24875111. |
the effects of propylthiouracil (ptu)-induced thyroid deficiency on the postnatal development of synaptic markers for cholinergic, gaba, dopaminergic and glutamate neurons in the rat corpus striatum were investigated. |
2014-06-02 |
2023-08-13 |
rat |
| Wen Zhang, Wenjing Yu, Daohan Wang, Li Wei, Minkyoung Lee, Sumei Wan. Effect of "jian-pi-zhi-dong decoction" on gamma-aminobutyric Acid in a mouse model of tourette syndrome. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-05-09. PMID:24812567. |
the purpose of this study was to explore the positive effects of jian-pi-zhi-dong decoction (jpzdd) on tourette syndrome (ts) by investigating the expression of gamma-aminobutyric acid (gaba) and its type a receptor (gabaar) in the striatum of a ts mice model. |
2014-05-09 |
2023-08-13 |
mouse |
| Wen Zhang, Wenjing Yu, Daohan Wang, Li Wei, Minkyoung Lee, Sumei Wan. Effect of "jian-pi-zhi-dong decoction" on gamma-aminobutyric Acid in a mouse model of tourette syndrome. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-05-09. PMID:24812567. |
we recorded the stereotypic behaviors of ts mice and measured the content of gaba in striatum by hplc and gabaar expression by immunohistochemistry and real-time pcr. |
2014-05-09 |
2023-08-13 |
mouse |
| Wen Zhang, Wenjing Yu, Daohan Wang, Li Wei, Minkyoung Lee, Sumei Wan. Effect of "jian-pi-zhi-dong decoction" on gamma-aminobutyric Acid in a mouse model of tourette syndrome. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-05-09. PMID:24812567. |
our results showed that jpzdd inhibited the abnormal behaviors of ts model mice and decreased gaba levels and gabaar protein and mrna expression in the striatum of ts model mice. |
2014-05-09 |
2023-08-13 |
mouse |
| Wen Zhang, Wenjing Yu, Daohan Wang, Li Wei, Minkyoung Lee, Sumei Wan. Effect of "jian-pi-zhi-dong decoction" on gamma-aminobutyric Acid in a mouse model of tourette syndrome. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-05-09. PMID:24812567. |
in brief, the mechanism by which jpzdd alleviates ts symptoms may be associated with gabaar expression downregulation in striatum which may regulate gaba metabolism. |
2014-05-09 |
2023-08-13 |
mouse |
| Regina Rumpel, Mesbah Alam, Alexander Klein, Meltem Özer, Maike Wesemann, Xingxing Jin, Joachim K Krauss, Kerstin Schwabe, Andreas Ratzka, Claudia Groth. Neuronal firing activity and gene expression changes in the subthalamic nucleus after transplantation of dopamine neurons in hemiparkinsonian rats. Neurobiology of disease. vol 59. 2014-05-05. PMID:23938762. |
although grafted rats displayed restored expression of the gaba synthesizing enzymes gad65 and gad67 in the striatum compared to naive rats, the grafts induced a decreased mrna expression of dopamine receptor drd2, glutamate receptors ampa3, nmda2a, and nmda2b, and glutamate transporter eaat3. |
2014-05-05 |
2023-08-12 |
rat |
| V De Chiara, C Motta, S Rossi, V Studer, F Barbieri, D Lauro, G Bernardi, D Centonz. Interleukin-1β alters the sensitivity of cannabinoid CB1 receptors controlling glutamate transmission in the striatum. Neuroscience. vol 250. 2014-04-04. PMID:23856068. |
furthermore, il1β has also been shown to control the sensitivity of cannabinoid cb1 receptors controlling gaba transmission (cb1rs(gaba)) in the striatum. |
2014-04-04 |
2023-08-12 |
Not clear |
| Linda W M van Kerkhof, Ruth Damsteegt, Viviana Trezza, Pieter Voorn, Louk J M J Vanderschure. Social play behavior in adolescent rats is mediated by functional activity in medial prefrontal cortex and striatum. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 10. 2014-03-24. PMID:23568326. |
using pharmacological inactivation methods, ie, infusions of gaba receptor agonists (baclofen and muscimol; b&m) or the ampa/kainate receptor antagonist 6,7-dinitroquinoxaline-2,3(1h,4h)-dione (dnqx), we investigated the involvement of several subregions of the medial pfc and striatum in social play. |
2014-03-24 |
2023-08-12 |
rat |
| Korah P Kuruvilla, M S Nandhu, Jes Paul, C S Paulos. Oxidative stress mediated neuronal damage in the corpus striatum of 6-hydroxydopamine lesioned Parkinson's rats: neuroprotection by serotonin, GABA and bone marrow cells supplementation. Journal of the neurological sciences. vol 331. issue 1-2. 2014-02-07. PMID:23726276. |
oxidative stress mediated neuronal damage in the corpus striatum of 6-hydroxydopamine lesioned parkinson's rats: neuroprotection by serotonin, gaba and bone marrow cells supplementation. |
2014-02-07 |
2023-08-12 |
rat |
| Korah P Kuruvilla, M S Nandhu, Jes Paul, C S Paulos. Oxidative stress mediated neuronal damage in the corpus striatum of 6-hydroxydopamine lesioned Parkinson's rats: neuroprotection by serotonin, GABA and bone marrow cells supplementation. Journal of the neurological sciences. vol 331. issue 1-2. 2014-02-07. PMID:23726276. |
6-ohda induced decreased activity of sod, cat and gpx in corpus striatum was significantly reversed to near control (p<0.001) by treatment with 5-ht, gaba and bone marrow cells. |
2014-02-07 |
2023-08-12 |
rat |
| Puneet Bagga, Anup N Chugani, Komanduri S Varadarajan, Anant B Pate. In vivo NMR studies of regional cerebral energetics in MPTP model of Parkinson's disease: recovery of cerebral metabolism with acute levodopa treatment. Journal of neurochemistry. vol 127. issue 3. 2013-12-10. PMID:23957451. |
mptp treatment led to reduction in paw grip strength and increased level of gaba and myo-inositol in striatum and olfactory bulb. |
2013-12-10 |
2023-08-12 |
mouse |
| Bianca Jupp, Daniele Caprioli, Niel Saigal, Ingrid Reverte, Saurav Shrestha, Paul Cumming, Barry J Everitt, Trevor W Robbins, Jeffrey W Dalle. Dopaminergic and GABA-ergic markers of impulsivity in rats: evidence for anatomical localisation in ventral striatum and prefrontal cortex. The European journal of neuroscience. vol 37. issue 9. 2013-10-28. PMID:23368520. |
we therefore used autoradiography to investigate da transporter (dat), 5-ht transporter (5-htt) and d1, d2/d3, μ-opioid and gaba(a) receptor binding in selected regions of the prefrontal cortex and striatum in rats expressing low and high impulsive behaviour on the five-choice serial reaction-time task. |
2013-10-28 |
2023-08-12 |
rat |
| Sarah Beggiato, Tiziana Antonelli, Maria Cristina Tomasini, Sergio Tanganelli, Kjell Fuxe, Robert Schwarcz, Luca Ferrar. Kynurenic acid, by targeting α7 nicotinic acetylcholine receptors, modulates extracellular GABA levels in the rat striatum in vivo. The European journal of neuroscience. vol 37. issue 9. 2013-10-28. PMID:23442092. |
kynurenic acid, by targeting α7 nicotinic acetylcholine receptors, modulates extracellular gaba levels in the rat striatum in vivo. |
2013-10-28 |
2023-08-12 |
rat |