| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lufei Shan, Oscar Diaz, Yajun Zhang, Bruce Ladenheim, Jean-Lud Cadet, Yung-Hsiao Chiang, Lars Olson, Barry J Hoffer, Cristina M Bäckma. L-Dopa induced dyskinesias in Parkinsonian mice: Disease severity or L-Dopa history. Brain research. vol 1618. 2016-04-25. PMID:26086365. |
gene array studies of striatal neurotransmitter receptors revealed changes in mrna expression levels for da, serotonin, glutamate and gaba receptors in striatum of 28-week old mitopark mice. |
2016-04-25 |
2023-08-13 |
mouse |
| Sumit Jamwal, Shamsher Singh, Navneet Kaur, Puneet Kuma. Protective Effect of Spermidine Against Excitotoxic Neuronal Death Induced by Quinolinic Acid in Rats: Possible Neurotransmitters and Neuroinflammatory Mechanism. Neurotoxicity research. vol 28. issue 2. 2016-03-23. PMID:26078029. |
on 21st day, animals were sacrificed and rat striatum was isolated for biochemical (lpo, gsh, nitrite), neuroinflammation (tnf-α, il-1β, and il-6), and neurochemical analysis (gaba, glutamate, dopamine, norepinephrine, serotonin, dopac, hva, 5-hiaa, adenosine, adenine, hypoxanthine, and inosine). |
2016-03-23 |
2023-08-13 |
rat |
| Sumit Jamwal, Shamsher Singh, Navneet Kaur, Puneet Kuma. Protective Effect of Spermidine Against Excitotoxic Neuronal Death Induced by Quinolinic Acid in Rats: Possible Neurotransmitters and Neuroinflammatory Mechanism. Neurotoxicity research. vol 28. issue 2. 2016-03-23. PMID:26078029. |
significantly attenuated these alterations in body weight, motor impairments, oxidative stress, neuroinflammatory markers, gaba, glutamate, catecholamines, adenosine, and their metabolites levels in striatum. |
2016-03-23 |
2023-08-13 |
rat |
| Yi-Na Sun, Tao Wang, Yong Wang, Ling-Na Han, Li-Bo Li, Yu-Ming Zhang, Jian Li. Activation of 5-HT₁A receptors in the medial subdivision of the central nucleus of the amygdala produces anxiolytic effects in a rat model of Parkinson's disease. Neuropharmacology. vol 95. 2016-03-08. PMID:25797491. |
the lesion induced anxiety-like behaviors, increased the firing rate and burst-firing pattern of cem γ-aminobutyric acid (gaba) neurons, as well as decreased dopamine (da) levels in the striatum, medial prefrontal cortex (mpfc), amygdala and ventral part of hippocampus (vhip). |
2016-03-08 |
2023-08-13 |
rat |
| David A Kupferschmidt, David M Lovinge. Inhibition of presynaptic calcium transients in cortical inputs to the dorsolateral striatum by metabotropic GABA(B) and mGlu2/3 receptors. The Journal of physiology. vol 593. issue 10. 2016-02-11. PMID:25781000. |
inhibition of presynaptic calcium transients in cortical inputs to the dorsolateral striatum by metabotropic gaba(b) and mglu2/3 receptors. |
2016-02-11 |
2023-08-13 |
Not clear |
| Michele Morari, Martina Fanti. Loss of the preferential control over the striato-nigral direct pathway by striatal NMDA receptors in a rat model of Parkinson's disease. The Analyst. vol 140. issue 11. 2016-02-10. PMID:25584655. |
using the same approach, we presently investigate whether reverse dialysis of nmda in the striatum differentially affects gaba release in the striatum and in striatal target areas, i.e. |
2016-02-10 |
2023-08-13 |
rat |
| Michele Morari, Martina Fanti. Loss of the preferential control over the striato-nigral direct pathway by striatal NMDA receptors in a rat model of Parkinson's disease. The Analyst. vol 140. issue 11. 2016-02-10. PMID:25584655. |
intrastriatal nmda elevated gaba levels at 0.1 μm (all regions) and 1 μm (striatum and gp only), but not at higher concentrations, indicating that, compared to naïve animals, the gaba response in snr was attenuated. |
2016-02-10 |
2023-08-13 |
rat |
| C G Perk, J R Wickens, B I Hylan. Differing properties of putative fast-spiking interneurons in the striatum of two rat strains. Neuroscience. vol 294. 2016-01-28. PMID:25758937. |
local circuits within the striatum of the basal ganglia include a small number of γ-aminobutyric acid (gaba)-ergic fast-spiking interneurons (fsi). |
2016-01-28 |
2023-08-13 |
rat |
| N P Kanunnikova, A G Vinitskaya, Y M Doroshenko, S M Zimatki. Brain GABA metabolism after chronic ethanol consumption and withdrawal in rats. Addiction biology. vol 2. issue 1. 2016-01-08. PMID:26735441. |
we showed decreased gaba levels in the brain stem, decreased gaba-at activity in the hemispheres and brain stem, and enhanced gaba-at activity in the striatum of ep rats compared with the control or wp animals following chronic consumption of ethanol. |
2016-01-08 |
2023-08-13 |
rat |
| Jilly Naaijen, David J Lythgoe, Houshang Amiri, Jan K Buitelaar, Jeffrey C Glenno. Fronto-striatal glutamatergic compounds in compulsive and impulsive syndromes: a review of magnetic resonance spectroscopy studies. Neuroscience and biobehavioral reviews. vol 52. 2015-12-30. PMID:25712432. |
firstly, a possible increase in glx (combination of glu, glutamine and gaba) in the striatum across adhd, ocd and asd. |
2015-12-30 |
2023-08-13 |
Not clear |
| Jolanta Konieczny, Anna Czarnecka, Kinga Kamińska, Tomasz Lenda, Przemysław Nowa. Decreased behavioral response to intranigrally administered GABAA agonist muscimol in the lactacystin model of Parkinson's disease may result from partial lesion of nigral non-dopamine neurons: comparison to the classical neurotoxin 6-OHDA. Behavioural brain research. vol 283. 2015-12-02. PMID:25655509. |
tissue da levels in the striatum and sn and gaba levels in the sn were also examined. |
2015-12-02 |
2023-08-13 |
rat |
| Jolanta Konieczny, Anna Czarnecka, Kinga Kamińska, Tomasz Lenda, Przemysław Nowa. Decreased behavioral response to intranigrally administered GABAA agonist muscimol in the lactacystin model of Parkinson's disease may result from partial lesion of nigral non-dopamine neurons: comparison to the classical neurotoxin 6-OHDA. Behavioural brain research. vol 283. 2015-12-02. PMID:25655509. |
we found that both lactacystin and 6-ohda induced a strong decrease in da level in the lesioned striatum and sn but only lactacystin slightly reduced gaba levels in the sn. |
2015-12-02 |
2023-08-13 |
rat |
| Balwant P Salunke, Sudhir N Umathe, Jagatpalsingh G Chava. Involvement of NMDA receptor in low-frequency magnetic field-induced anxiety in mice. Electromagnetic biology and medicine. vol 33. issue 4. 2015-11-02. PMID:24131395. |
in addition, levels of gaba and glutamate were determined in regions of the brain viz, cortex, striatum, hippocampus and hypothalamus. |
2015-11-02 |
2023-08-12 |
mouse |
| T Meng, S Yuan, Z Zheng, T Liu, L Li. Effects of endogenous melatonin on glutamate and GABA rhythms in the striatum of unilateral 6-hydroxydopamine-lesioned rats. Neuroscience. vol 286. 2015-09-14. PMID:25499317. |
effects of endogenous melatonin on glutamate and gaba rhythms in the striatum of unilateral 6-hydroxydopamine-lesioned rats. |
2015-09-14 |
2023-08-13 |
rat |
| T Meng, S Yuan, Z Zheng, T Liu, L Li. Effects of endogenous melatonin on glutamate and GABA rhythms in the striatum of unilateral 6-hydroxydopamine-lesioned rats. Neuroscience. vol 286. 2015-09-14. PMID:25499317. |
three weeks following 6-ohda lesioning, there was a significant increase in extracellular glu (156%) and decrease in gaba (15%) and da (85%) in the lesioned striatum. |
2015-09-14 |
2023-08-13 |
rat |
| T Meng, S Yuan, Z Zheng, T Liu, L Li. Effects of endogenous melatonin on glutamate and GABA rhythms in the striatum of unilateral 6-hydroxydopamine-lesioned rats. Neuroscience. vol 286. 2015-09-14. PMID:25499317. |
in addition, significant variations in extracellular levels of glu and gaba between day and night were observed in vehicle-treated rat striatum. |
2015-09-14 |
2023-08-13 |
rat |
| T Meng, S Yuan, Z Zheng, T Liu, L Li. Effects of endogenous melatonin on glutamate and GABA rhythms in the striatum of unilateral 6-hydroxydopamine-lesioned rats. Neuroscience. vol 286. 2015-09-14. PMID:25499317. |
six weeks post-treatment, mlt levels correlated well with glu and gaba levels at corresponding time-points in the striatum ipsilateral to the injected side in both groups, and increased mlt levels also correlated well with changes in glu and gaba in the striatum in 6-ohda-lesioned rats. |
2015-09-14 |
2023-08-13 |
rat |
| Robert J Buchanan, Klevest Gjini, David Darrow, Georgeta Varga, Jennifer L Robinson, Zoltan Nadasd. Glutamate and GABA concentration changes in the globus pallidus internus of Parkinson's patients during performance of implicit and declarative memory tasks: a report of two subjects. Neuroscience letters. vol 589. 2015-08-27. PMID:25596441. |
these results are in line with hypothesized changes in these neurotransmitter levels: an increase of excitatory (glu) input from subthalamic nucleus (stn) to gpi during implicit memory task performance and a decrease of inhibitory inputs (gaba) from globus pallidus externus (gpe) and striatum to gpi during declarative memory performance. |
2015-08-27 |
2023-08-13 |
human |
| H J Waldvogel, R L M Faul. The diversity of GABA(A) receptor subunit distribution in the normal and Huntington's disease human brain. Advances in pharmacology (San Diego, Calif.). vol 73. 2015-08-03. PMID:25637443. |
in huntington's disease, the variable loss of gabaergic medium spiny striatopallidal projection neurons is associated with a loss of gaba(a) receptor subunits in the striosome and/or the matrix compartments of the striatum. |
2015-08-03 |
2023-08-13 |
human |
| Bo-Eun Yoon, Junsung Woo, Ye-Eun Chun, Heejung Chun, Seonmi Jo, Jin Young Bae, Heeyoung An, Joo Ok Min, Soo-Jin Oh, Kyung-Seok Han, Hye Yun Kim, Taekeun Kim, Young Soo Kim, Yong Chul Bae, C Justin Le. Glial GABA, synthesized by monoamine oxidase B, mediates tonic inhibition. The Journal of physiology. vol 592. issue 22. 2015-07-24. PMID:25239459. |
in the cerebellum and striatum of adult mice, general gene silencing, knock out of maob or selegiline treatment resulted in elimination of tonic gaba currents recorded from granule neurons and medium spiny neurons. |
2015-07-24 |
2023-08-13 |
mouse |