| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S J Enna, E D Bird, J P Bennett, D B Bylund, H I Yamamura, L L Iversen, S H Snyde. Huntington's chorea. Changes in neurotransmitter receptors in the brain. The New England journal of medicine. vol 294. issue 24. 1976-07-06. PMID:4733. |
by contrast, gamma-aminobutyric acid and beta-adrenergic receptor binding were not significantly different in choreic and control caudate nucleus or cortex, suggesting that, despite the loss of gamma-aminobutyric-acid-synthesizing ability in the corpus striatum, gamma-aminobuytric acid mimetic drugs might alleviate the movement disorders in huntington's chorea. |
1976-07-06 |
2023-08-11 |
Not clear |
| B C Patel, P Crosset, H L Klawan. Failure of increased brain gamma-aminobutyric acid levels to influence amphetamine-induced stereotyped behavior. Research communications in chemical pathology and pharmacology. vol 12. issue 4. 1976-04-19. PMID:766131. |
this observation raises some doubt as to whether gaba plays a role in the physiology of the striatum and suggests that gaba does not play a role in the pathophysiology of chorea. |
1976-04-19 |
2023-08-11 |
human |
| S P Banerjee, S H Snyder, R Mechoula. Cannabinoids: influence on neurotransmitter uptake in rat brain synaptosomes. The Journal of pharmacology and experimental therapeutics. vol 194. issue 1. 1975-10-30. PMID:168349. |
delta1-thc inhibits the accumulation of ne and 5-ht into hypothalamic preparations and da into the corpus striatum with ki values of about 12 to 25 mum while gaba uptake into cerebral cortical preparations is inhibited less (ki = 140 mum). |
1975-10-30 |
2023-08-11 |
rat |
| J S Kim, R Hassle. Effects of acute haloperidol on the gamma-aminobutyric acid system in rat striatum and substantia nigra. Brain research. vol 88. issue 1. 1975-07-07. PMID:1122395. |
effects of acute haloperidol on the gamma-aminobutyric acid system in rat striatum and substantia nigra. |
1975-07-07 |
2023-08-11 |
rat |
| J Storm-Mathise. High affinity uptake of GABA in presumed GABA-ERGIC nerve endings in rat brain. Brain research. vol 84. issue 3. 1975-06-27. PMID:1122379. |
hence about two-thirds of the gaba uptake activity in substantia nigra are localised, to the alleged gaba-ergic nerve elements originating from corpus striatum. |
1975-06-27 |
2023-08-11 |
rat |
| S R Zukin, A B Young, S H Snyde. Gamma-aminobutyric acid binding to receptor sites in the rat central nervous system. Proceedings of the National Academy of Sciences of the United States of America. vol 71. issue 12. 1975-03-10. PMID:4155072. |
[(3)h]gaba binding is greatest in the cerebellum, least in the spinal cord and medulla oblongatapons, with intermediate values in the thalamus, hippocampus, hypothalamus, cerebral cortex, midbrain, and corpus striatum. |
1975-03-10 |
2023-08-11 |
rat |
| J S Ki. Effects of 6-hydroxydopamine on acetylcholine and GABA metabolism in rat striatum. Brain research. vol 55. issue 2. 1973-08-28. PMID:4714016. |
effects of 6-hydroxydopamine on acetylcholine and gaba metabolism in rat striatum. |
1973-08-28 |
2023-08-11 |
rat |
| I J Bak, R Hassler, J S Kim, K Kataok. Amantadine actions on acetylcholine and GABA in striatum and substantia nigra of rat in relation to behavioral changes. Journal of neural transmission. vol 33. issue 1. 1973-02-17. PMID:4674484. |
amantadine actions on acetylcholine and gaba in striatum and substantia nigra of rat in relation to behavioral changes. |
1973-02-17 |
2023-08-11 |
rat |
| M J Kuhar, A I Green, S H Snyder, E Gfelle. Separation of synaptosomes storing catecholamines and gamma-aminobutyric acid in rat corpus striatum. Brain research. vol 21. issue 3. 1970-10-28. PMID:5456733. |
separation of synaptosomes storing catecholamines and gamma-aminobutyric acid in rat corpus striatum. |
1970-10-28 |
2023-08-11 |
rat |
| A Herz, H v Freytag-Loringhove. [Synaptic excitation in the corpus striatum and the antagonistic effect of microelectrophoretically applied glutamic acid and GABA]. Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere. vol 299. issue 2. 1969-01-23. PMID:5247217. |
[synaptic excitation in the corpus striatum and the antagonistic effect of microelectrophoretically applied glutamic acid and gaba]. |
1969-01-23 |
2023-08-11 |
Not clear |