| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Musella, D Fresegna, F R Rizzo, A Gentile, S Bullitta, F De Vito, L Guadalupi, D Centonze, G Mandoles. A novel crosstalk within the endocannabinoid system controls GABA transmission in the striatum. Scientific reports. vol 7. issue 1. 2019-02-18. PMID:28779174. |
our results indicate that pea, acting on gpr55, enhances gaba transmission in the striatum, and triggers a parallel synthesis of 2-ag at the postsynaptic site, that in turn acts in a retrograde manner to inhibit gaba release through the stimulation of presynaptic cb1rs. |
2019-02-18 |
2023-08-13 |
Not clear |
| Edna Maria Camelo Chaves, Jose Eduardo Ribeiro Honório-Júnior, Caren Nádia Soares Sousa, Valdécio Silveira Monteiro, Dayanne Terra Tenório Nonato, Leonardo Pimentel Dantas, Ana Silvia Suassuna Carneiro Lúcio, José Maria Barbosa-Filho, Manoel Cláudio Azevedo Patrocínio, Glauce Socorro Barros Viana, Silvânia Maria Mendes Vasconcelo. The anxiolytic-like effect of 6-styryl-2-pyrone in mice involves GABAergic mechanism of action. Metabolic brain disease. vol 33. issue 1. 2019-01-31. PMID:29086102. |
after behavioral tests, these animals were sacrificed and had their prefrontal cortex (pfc), hippocampus (hc) and striatum (st) dissected for assaying amino acids (aspartate- asp, glutamate- glu, glycine- gly, taurine- tau and gamma-aminobutyric acid- gaba). |
2019-01-31 |
2023-08-13 |
mouse |
| Ana Paula Chiapinotto Ceretta, Catiuscia Molz de Freitas, Larissa Finger Schaffer, Jeane Binotto Reinheimer, Mariana Maikéli Dotto, Elizete de Moraes Reis, Rahisa Scussel, Ricardo Andrez Machado-de-Ávila, Roselei Fachinett. Gabapentin reduces haloperidol-induced vacuous chewing movements in mice. Pharmacology, biochemistry, and behavior. vol 166. 2019-01-09. PMID:29374574. |
these results suggest that treatment with gabapentin, an analog of gaba, can attenuate the vcms induced by acute haloperidol treatment in mice without alterations in monoamine levels, th, or gad67 immunoreactivity in the striatum. |
2019-01-09 |
2023-08-13 |
mouse |
| Monika M Gola. Human cellular models of medium spiny neuron development and Huntington disease. Life sciences. vol 209. 2018-10-15. PMID:30031060. |
the loss of gamma-aminobutyric acid (gaba)-ergic medium spiny neurons (msns) in the striatum is the hallmark of huntington disease (hd), an incurable neurodegenerative disorder characterized by progressive motor, psychiatric, and cognitive symptoms. |
2018-10-15 |
2023-08-13 |
human |
| Shamsher Singh, Puneet Kuma. Piperine in combination with quercetin halt 6-OHDA induced neurodegeneration in experimental rats: Biochemical and neurochemical evidences. Neuroscience research. vol 133. 2018-10-09. PMID:29056550. |
on 22nd day, animals were sacrificed and striatum homogenates were used for biochemical (lpo, gsh, nitrite), neuroinflammatory (tnf-α, il-1 β and il-6) and neurotransmitter (dopamine, norepinephrine, serotonin, gaba, glutamate) analysis. |
2018-10-09 |
2023-08-13 |
rat |
| Kurt M Fraser, Patricia H Jana. Long-lasting contribution of dopamine in the nucleus accumbens core, but not dorsal lateral striatum, to sign-tracking. The European journal of neuroscience. vol 46. issue 4. 2018-09-06. PMID:28699296. |
after 7 or 14 training sessions, rats received infusions of saline, the dopamine antagonist flupenthixol, or the gaba agonists baclofen and muscimol into the nacc or the dorsal lateral striatum (dls). |
2018-09-06 |
2023-08-13 |
rat |
| Georgia Mandolesi, Silvia Bullitta, Diego Fresegna, Antonietta Gentile, Francesca De Vito, Ettore Dolcetti, Francesca R Rizzo, Georgios Strimpakos, Diego Centonze, Alessandra Musell. Interferon-γ causes mood abnormalities by altering cannabinoid CB1 receptor function in the mouse striatum. Neurobiology of disease. vol 108. 2018-07-23. PMID:28757328. |
intracerebroventricular delivery of ifn-γ caused a depressive- and anxiety-like behavior in mice, associated with the selective dysfunction of cb1rs controlling gaba transmission in the striatum. |
2018-07-23 |
2023-08-13 |
mouse |
| Liping Sun, Keyue Wang, Yan Li, Qiyuan Fan, Wei Zheng, Hong L. Vanadium exposure-induced striatal learning and memory alterations in rats. Neurotoxicology. vol 62. 2018-05-30. PMID:28625925. |
interestingly, with the increase of the dose of vanadium, the contents of neurotransmitter ach, 5-ht and gaba in the striatum increased; however, the levels of syn1 was significantly reduced in the exposed groups compared with controls (p<0.05). |
2018-05-30 |
2023-08-13 |
rat |
| David Calderón Guzmán, Maribel Ortiz Herrera, Norma Osnaya Brizuela, Gerardo Barragán Mejía, Ernestina Hernández García, Hugo Juárez Olguín, Norma Labra Ruíz, Armando Valenzuela Peraz. Oseltamivir and indomethacin reduce the oxidative stress in brain and stomach of infected rats. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 126. issue 2. 2018-05-03. PMID:29271004. |
levels of gaba increased in stomach and cortex of ir with oseltamivir, but decreased in striatum and cerebellum/medulla oblongata of ir with indomethacin. |
2018-05-03 |
2023-08-13 |
rat |
| Hyun Jin Kim, Joo Han Lee, Kyunghwa Yun, Joung-Hun Ki. Alterations in Striatal Circuits Underlying Addiction-Like Behaviors. Molecules and cells. vol 40. issue 6. 2018-04-13. PMID:28724279. |
among the involved brain areas, including those of the reward system, the striatum is the major area of convergence for glutamate, gaba, and dopamine transmission, and this brain region potentially determines stereotyped behaviors. |
2018-04-13 |
2023-08-13 |
Not clear |
| John J O'Connor, Carmel O'Neil. A Role for Adenosine A1 Receptors in GABA and NMDA-Receptor Mediated Modulation of Dopamine Release: Studies Using Fast Cyclic Voltammetry. Sensors (Basel, Switzerland). vol 8. issue 9. 2018-01-04. PMID:27873828. |
in the striatum many neurotransmitters including gaba, glutamate, acetylcholine, dopamine, nitric oxide and adenosine interact to regulate synaptic transmission. |
2018-01-04 |
2023-08-13 |
rat |
| Muthiah Ramanathan, Khadar K Abdul, Antony Justi. Low dose of L-glutamic acid attenuated the neurological dysfunctions and excitotoxicity in bilateral common carotid artery occluded mice. Behavioural pharmacology. vol 27. issue 7. 2018-01-03. PMID:27564990. |
l-ga reduced glutamate levels in the cortex, striatum, and hippocampus at 72 h, whereas gaba levels were elevated in all three brain regions studied. |
2018-01-03 |
2023-08-13 |
mouse |
| Mei Han, Rebeca Mejias, Shu-Ling Chiu, Rebecca Rose, Abby Adamczyk, Richard Huganir, Tao Wan. Mice lacking GRIP1/2 show increased social interactions and enhanced phosphorylation at GluA2-S880. Behavioural brain research. vol 321. 2017-11-29. PMID:28063882. |
we determined the expression profile of key signaling proteins in ampar, mglur, mtor, and gaba pathways in frontal cortex, striatum, and cerebellum of dko mice. |
2017-11-29 |
2023-08-13 |
mouse |
| Marc Deffains, Liliya Iskhakova, Shiran Katabi, Suzanne N Haber, Zvi Israel, Hagai Bergma. Subthalamic, not striatal, activity correlates with basal ganglia downstream activity in normal and parkinsonian monkeys. eLife. vol 5. 2017-10-23. PMID:27552049. |
the striatum and the subthalamic nucleus (stn) constitute the input stage of the basal ganglia (bg) network and together innervate bg downstream structures using gaba and glutamate, respectively. |
2017-10-23 |
2023-08-13 |
monkey |
| Wei Wei, Shengyuan Ding, Fu-Ming Zho. Dopaminergic treatment weakens medium spiny neuron collateral inhibition in the parkinsonian striatum. Journal of neurophysiology. vol 117. issue 3. 2017-09-13. PMID:27927785. |
furthermore, whereas the homotypic preference, one-way directionality and the basal inhibitory strength were preserved, da inhibited gaba release at the d2-msn→d2-msn collateral synapse in a supersensitive manner in the da-denervated striatum. |
2017-09-13 |
2023-08-13 |
mouse |
| Wei Wei, Shengyuan Ding, Fu-Ming Zho. Dopaminergic treatment weakens medium spiny neuron collateral inhibition in the parkinsonian striatum. Journal of neurophysiology. vol 117. issue 3. 2017-09-13. PMID:27927785. |
in contrast, for d1-msn-originated collateral connections, whereas d1 agonism facilitated d1-msn→d1-msn collateral inhibition in the normal striatum, this presynaptic d1r facilitation of gaba release was lost in the parkinsonian striatum. |
2017-09-13 |
2023-08-13 |
mouse |
| Andrea Herrera, Patricia Muñoz, Irmgard Paris, Gabriela Díaz-Veliz, Sergio Mora, Jose Inzunza, Kjell Hultenby, Cesar Cardenas, Fabián Jaña, Rita Raisman-Vozari, Katia Gysling, Jorge Abarca, Harry W M Steinbusch, Juan Segura-Aguila. Aminochrome induces dopaminergic neuronal dysfunction: a new animal model for Parkinson's disease. Cellular and molecular life sciences : CMLS. vol 73. issue 18. 2017-08-23. PMID:27001668. |
the unilateral injection of aminochrome into rat striatum resulted in (1) contralateral rotation when the animals are stimulated with apomorphine; (2) absence of significant loss of tyrosine hydroxylase-positive neuronal elements both in substantia nigra and striatum; (3) cell shrinkage; (4) significant reduction of dopamine release; (5) significant increase in gaba release; (6) significant decrease in the number of monoaminergic presynaptic vesicles; (7) significant increase of dopamine concentration inside of monoaminergic vesicles; (8) significant increase of damaged mitochondria; (9) significant decrease of atp level in the striatum (10) significant decrease in basal and maximal mitochondrial respiration. |
2017-08-23 |
2023-08-13 |
rat |
| Anne Almey, Teresa A Milner, Wayne G Brak. Estrogen receptor α and G-protein coupled estrogen receptor 1 are localized to GABAergic neurons in the dorsal striatum. Neuroscience letters. vol 622. 2017-07-19. PMID:27080432. |
gabaergic neurons are the most common type of neuron in the striatum, and changes in gaba transmission affect dopamine transmission. |
2017-07-19 |
2023-08-13 |
Not clear |
| Anne Almey, Teresa A Milner, Wayne G Brak. Estrogen receptor α and G-protein coupled estrogen receptor 1 are localized to GABAergic neurons in the dorsal striatum. Neuroscience letters. vol 622. 2017-07-19. PMID:27080432. |
thus, to determine whether erα or gper1 are localized to gabaergic neurons, we double labeled the striatum with antibodies for erα or gper1 and gaba and examined them using electron microscopy. |
2017-07-19 |
2023-08-13 |
Not clear |
| Anne Almey, Teresa A Milner, Wayne G Brak. Estrogen receptor α and G-protein coupled estrogen receptor 1 are localized to GABAergic neurons in the dorsal striatum. Neuroscience letters. vol 622. 2017-07-19. PMID:27080432. |
ultrastructural analysis revealed that erα and gper1 are localized exclusively to extranuclear sites in the striatum, and ∼35% of the dendrites and axon terminals labeled for these receptors contain gaba immunoreactivity. |
2017-07-19 |
2023-08-13 |
Not clear |