Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Asami Umino, Hisayuki Iwama, Masakazu Umino, Dai Shimazu, Yuji Kiuchi, Toru Nishikaw. Effects of Quinolinate-Induced Lesion of the Medial Prefrontal Cortex on Prefrontal and Striatal Concentrations of D-Serine in the Rat. Neurochemical research. 2022-05-23. PMID:35604516. |
a prominent reduction in the tissue levels of gaba in the interneurons of the prefrontal cortex (- 78%) without significant changes in those in the striatum (+ 12%) verified that a major lesion part was confined to the cortical portion. |
2022-05-23 |
2023-08-13 |
rat |
Sarah M Zych, Christopher P For. Divergent properties and independent regulation of striatal dopamine and GABA co-transmission. Cell reports. vol 39. issue 7. 2022-05-18. PMID:35584679. |
both dopamine and gaba are loaded into snc synaptic vesicles by the vesicular monoamine transporter 2 (vmat2), and co-release of gaba provides strong inhibition to the striatum by directly inhibiting striatal medium spiny projection neurons (msns) through activation of gaba |
2022-05-18 |
2023-08-13 |
Not clear |
Ana Paula Pesarico, José L Cechella, Cristina W Nogueira, Suzan G Ros. Swimming exercise and diphenyl diselenide-supplemented diet modulate cerebral cortical and striatal GABA uptake in aged rats. Anais da Academia Brasileira de Ciencias. vol 94. issue 1. 2022-01-12. PMID:35019002. |
after 4 weeks, the [3h]gaba uptake was determined in samples of cerebral cortex and striatum of rats. |
2022-01-12 |
2023-08-13 |
rat |
Regina Célia Cussa Kubrusly, Thais da Rosa Valli, Mariana Nunes Marinho Ritter Ferreira, Pâmella de Moura, Vladimir Pedro Peralva Borges-Martins, Robertta Silva Martins, Danielle Dias Pinto Ferreira, Matheus Figueiredo Sathler, Ricardo Augusto de Melo Reis, Gustavo Costa Ferreira, Alex Christian Manhães, Maurício Dos Santos Pereir. Caffeine Improves GABA Transport in the Striatum of Spontaneously Hypertensive Rats (SHR). Neurotoxicity research. vol 39. issue 6. 2021-12-03. PMID:34637050. |
caffeine improves gaba transport in the striatum of spontaneously hypertensive rats (shr). |
2021-12-03 |
2023-08-13 |
rat |
Rie Tohge, Satoshi Kaneko, Satoshi Morise, Mitsuaki Oki, Norihiro Takenouchi, Aya Murakami, Masataka Nakamura, Hirofumi Kusaka, Yusuke Yakushij. Zonisamide attenuates the severity of levodopa-induced dyskinesia via modulation of the striatal serotonergic system in a rat model of Parkinson's disease. Neuropharmacology. vol 198. 2021-10-14. PMID:34474045. |
glutamate, gaba, acetylcholine, dopamine, and serotonin interact with each other to regulate the flow of neural information in the striatum. |
2021-10-14 |
2023-08-13 |
rat |
Nina Dolfen, Menno P Veldman, Mareike A Gann, Andreas von Leupoldt, Nicolaas A J Puts, Richard A E Edden, Mark Mikkelsen, Stephan Swinnen, Lars Schwabe, Geneviève Albouy, Bradley R Kin. A role for GABA in the modulation of striatal and hippocampal systems under stress. Communications biology. vol 4. issue 1. 2021-09-24. PMID:34475515. |
regression analyses indicated that stress modulated the link between striatal gaba levels and functional plasticity in both the hippocampus and striatum during learning as measured with fmri. |
2021-09-24 |
2023-08-13 |
Not clear |
E Fernández-Espejo, L Núñez-Domíngue. Endocannabinoid-mediated synaptic plasticity and substance use disorders. Neurologia (Barcelona, Spain). 2021-09-20. PMID:34538595. |
in the short term, we may stress "inhibitory" phenomena, such as depolarisation-induced suppression of inhibition and depolarisation-induced suppression of excitation, and such "disinhibitory" phenomena as long-lasting disinhibition of neuronal activity, particularly in the striatum, and suppression of hippocampal gaba release. |
2021-09-20 |
2023-08-13 |
Not clear |
Durairaj Ragu Varman, Mark A Subler, Jolene J Windle, Lankupalle D Jayanthi, Sammanda Ramamoorth. Novelty-induced hyperactivity and suppressed cocaine induced locomotor activation in mice lacking threonine 53 phosphorylation of dopamine transporter. Behavioural brain research. vol 408. 2021-09-02. PMID:33794225. |
dat-ala53 mice displayed unaltered levels of monoamines, glutamate, and gaba in the striatum compared to wt. |
2021-09-02 |
2023-08-13 |
mouse |
Lydia Lebenheim, Sam A Booker, Christian Derst, Torsten Weiss, Franziska Wagner, Clemens Gruber, Imre Vida, Daniel S Zahm, Rüdiger W Ve. A novel giant non-cholinergic striatal interneuron restricted to the ventrolateral striatum coexpresses Kv3.3 potassium channel, parvalbumin, and the vesicular GABA transporter. Molecular psychiatry. 2021-08-12. PMID:33190145. |
a novel giant non-cholinergic striatal interneuron restricted to the ventrolateral striatum coexpresses kv3.3 potassium channel, parvalbumin, and the vesicular gaba transporter. |
2021-08-12 |
2023-08-13 |
Not clear |
Daisuke Kawakami, Mitsuki Tsuchiya, Tasuku Murata, Akira Iguchi, Kei Zaits. Rapid quantification of extracellular neurotransmitters in mouse brain by PESI/MS/MS and longitudinal data analysis using the R and Stan-based Bayesian state-space model. Talanta. vol 234. 2021-08-10. PMID:34364429. |
we performed a rapid analysis for quantifying extracellular l-glutamic acid (l-glu) and gamma-aminobutyric acid (gaba) in the mouse striatum by combined use of probe electrospray ionization/tandem mass spectrometry (pesi/ms/ms) and in vivo brain microdialysis. |
2021-08-10 |
2023-08-13 |
mouse |
Barbara Morera Maiquez, Hilmar P Sigurdsson, Katherine Dyke, Eleri Clarke, Polly McGrath, Matthew Pasche, Anupriya Rajendran, Georgina M Jackson, Stephen R Jackso. Entraining Movement-Related Brain Oscillations to Suppress Tics in Tourette Syndrome. Current biology : CB. vol 30. issue 12. 2021-08-09. PMID:32502412. |
ts is associated with the following: dysfunction within cortical-striatal-thalamic-cortical (cstc) brain circuits implicated in the selection of movements, impaired operation of gaba signaling within the striatum, and hyper-excitability of cortical sensorimotor regions that might contribute to the occurrence of tics. |
2021-08-09 |
2023-08-13 |
Not clear |
Arti Rana, Shamsher Singh, Rahul Deshmukh, Anoop Kuma. Pharmacological potential of tocopherol and doxycycline against traumatic brain injury-induced cognitive/motor impairment in rats. Brain injury. vol 34. issue 8. 2021-07-28. PMID:32493074. |
on 29th day, animals were sacrificed and striatum and cortex were homogenized for the estimation of biochemical (lpo, nitrite, and gsh), neuroinflammatory (il-6, il-1β, and tnf-α), and neurotransmitters (dopamine, norepinephrine, serotonin, gaba, and glutamate) analysis. |
2021-07-28 |
2023-08-13 |
rat |
Yongwoo Yoon, Hyun Sook Kim, Iksoo Jeon, Jeong-Eun Noh, Hyun Jung Park, Suji Lee, In-Hyun Park, Lara Stevanato, Caroline Hicks, Randolph Corteling, Roger A Barker, John D Sinden, Jihwan Son. Implantation of the clinical-grade human neural stem cell line, CTX0E03, rescues the behavioral and pathological deficits in the quinolinic acid-lesioned rodent model of Huntington's disease. Stem cells (Dayton, Ohio). vol 38. issue 8. 2021-07-09. PMID:32374064. |
transplanted ctx0e03 formed msns (darpp-32) and gabaergic neurons (gaba, gad65/67) with bdnf expression in the striatum, while cortically transplanted cells formed tbr1-positive neurons. |
2021-07-09 |
2023-08-13 |
human |
Khadga Raj, G D Gupta, Shamsher Sing. l-Theanine ameliorates motor deficit, mitochondrial dysfunction, and neurodegeneration against chronic tramadol induced rats model of Parkinson's disease. Drug and chemical toxicology. 2021-07-02. PMID:34210222. |
on the day 29, all wistar rats were sacrificed and striatum homogenates were used for biochemical (lipid peroxidation, nitrite, glutathione, glutathione peroxidase activity, superoxide dismutase, catalase, mitochondrial complex i, iv, and cyclic adenosine monophosphate), neuroinflammatory markers (tumor necrosis factor-α, interleukin-1β, and interleukin-17), and neurotransmitters (dopamine, norepinephrine, serotonin, gaba, and glutamate) analysis. |
2021-07-02 |
2023-08-13 |
rat |
Hilmar P Sigurdsson, Stephen R Jackson, Soyoung Kim, Katherine Dyke, Georgina M Jackso. A feasibility study for somatomotor cortical mapping in Tourette syndrome using neuronavigated transcranial magnetic stimulation. Cortex; a journal devoted to the study of the nervous system and behavior. vol 129. 2021-06-21. PMID:32474291. |
converging evidence indicates abnormal brain network function in ts may be largely due to the impaired operation of gaba signalling within the striatum and within cortical motor areas, leading to the occurrence of tics. |
2021-06-21 |
2023-08-13 |
Not clear |
M E Chávez-Pichardo, D Y Reyes-Bravo, M S Mendoza-Trejo, A G Marín-López, M Giordano, N Hernández-Chan, K Domínguez-Marchan, L C Ortega-Rosales, V M Rodrígue. Brain alterations in GABA, glutamate and glutamine markers after chronic atrazine exposure in the male albino rat. Archives of toxicology. vol 94. issue 9. 2021-06-16. PMID:32561961. |
to evaluate the impact of atr on motor and anxiety tasks, tissue levels of gaba, glutamate, glutamine, and extracellular and potassium-evoked release of glutamate in the striatum, we daily exposed sprague-dawley male rats to 1 or 10 mg atr/kg of body weight for 12-14 months. |
2021-06-16 |
2023-08-13 |
rat |
E Fernández-Espejo, L Núñez-Domíngue. Endocannabinoid-mediated synaptic plasticity and substance use disorders. Neurologia (Barcelona, Spain). 2021-05-27. PMID:30857785. |
in the short term, we may stress «inhibitory» phenomena, such as depolarisation-induced suppression of inhibition and depolarisation-induced suppression of excitation, and such «disinhibitory» phenomena as long-lasting disinhibition of neuronal activity, particularly in the striatum, and suppression of hippocampal gaba release. |
2021-05-27 |
2023-08-13 |
Not clear |
Shujing Wang, Ziteng Deng, Jia Wang, Wenjun Zhang, Fenghua Liu, Jianqin Xu, Yunfei M. Decreased GABAergic signaling, fewer parvalbumin-, somatostatin- and calretinin-positive neurons in brain of a rat model of simulated transport stress. Research in veterinary science. vol 134. 2021-03-22. PMID:33360121. |
this study aimed to explore the effect of stress on behavior, hpa axis, gaba transmitters and the distribution of gabaergic interneurons in the prefrontal cortex (pfc) and striatum of the brain by a rat model of simulated transport stress (sts). |
2021-03-22 |
2023-08-13 |
rat |
Yan Jin, Qian Meng, Lisheng Mei, Wenjie Zhou, Xia Zhu, Yu Mao, Wen Xie, Xulai Zhang, Min-Hua Luo, Wenjuan Tao, Haitao Wang, Jie Li, Juan Li, Xiangyao Li, Zhi Zhan. A somatosensory cortex input to the caudal dorsolateral striatum controls comorbid anxiety in persistent pain. Pain. vol 161. issue 2. 2021-02-02. PMID:31651582. |
using viral neuronal tracing in mice, we identified a previously unknown pathway whereby glutamatergic neurons from layer 5 of the hindlimb primary somatosensory cortex (s1) (glu), a well-known brain region involved in pain processing, project to gabaergic neurons in the caudal dorsolateral striatum (gaba). |
2021-02-02 |
2023-08-13 |
mouse |
Indrani Datta, S R Mekha, Alka Kaushal, Kavina Ganapathy, Rema Razda. Influence of intranasal exposure of MPTP in multiple doses on liver functions and transition from non-motor to motor symptoms in a rat PD model. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 2. 2021-01-04. PMID:31468077. |
decreases in dopamine, noradrenaline, and gaba and increase in serotonin were detected in striatum. |
2021-01-04 |
2023-08-13 |
rat |