| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M E Appleyard, A R Gree. Acetylcholinesterase activity in regions of rat brain following repeated administration of electroconvulsive shock. Journal of psychopharmacology (Oxford, England). vol 1. issue 3. 2012-10-02. PMID:22158982. |
this change in the striatum may be associated with the change in gaba synthesis which has been shown to also occur in this region at the same time. |
2012-10-02 |
2023-08-12 |
rat |
| P Westerling, S Lindgren, B J Meyerso. The behavioural effects of chronic elevation of rat brain GABA by ethanolamine O-sulphate. Journal of psychopharmacology (Oxford, England). vol 3. issue 3. 2012-10-02. PMID:22282897. |
this effect was accompanied by an accumulation of gaba in the substantia nigra and the corpus striatum. |
2012-10-02 |
2023-08-12 |
rat |
| Vincent Van Waes, Joel A Beverley, Homayoun Siman, Kuei Y Tseng, Heinz Steine. CB1 Cannabinoid Receptor Expression in the Striatum: Association with Corticostriatal Circuits and Developmental Regulation. Frontiers in pharmacology. vol 3. 2012-10-02. PMID:22416230. |
the regional distribution of cb1 receptor expression in the striatum further suggests that, in sensorimotor sectors, cb1 receptors mostly regulate gaba inputs from local axon collaterals of projection neurons, whereas in associative/limbic sectors, cb1 regulation of gaba inputs from interneurons and glutamate inputs may be more important. |
2012-10-02 |
2023-08-12 |
rat |
| N Lagos, F Valdés, F Orreg. A search for endogenous modulators of the GABA receptor in different regions of the rat CNS. Neurochemistry international. vol 5. issue 3. 2012-10-02. PMID:20487956. |
the possible existence of endogenous substances other than ?-aminobutyric acid (gaba), that can also bind to rat brain gaba receptors, has been investigated in synaptic membranes derived from whole rat brain, or from cerebral cortex; as well as in isolated synaptic vesicles obtained from cerebral cortex, striatum, hypothalamus, cerebellum and spinal cord and in the superfusion fluid of electrically stimulated brain cortex slices, where a gaba-like substance is released by a calcium-dependent process. |
2012-10-02 |
2023-08-12 |
rat |
| C Goetz, S Bourgoin, F Cesselin, A Brandi, D Bression, M Martinet, F Peillon, M Hamo. Alterations in central neurotransmitter receptor binding sites following estradiol implantation in female rats. Neurochemistry international. vol 5. issue 4. 2012-10-02. PMID:20487964. |
examination of neurotransmitter receptors in the hippocampus, striatum and cerebral cortex one month after the implantation revealed that estrogenization was associated with: an increased density of (3)h-domperidone binding sites (d(2) receptors) in the striatum and reduced numbers of (3)h-serotonin high affinity sites (5-ht(1) receptors) in the hippocampus and of (3)h-muscimol binding sites (gaba receptors) in the hippocampus, striatum and cerebral cortex. |
2012-10-02 |
2023-08-12 |
rat |
| Y Yoneda, K Kanmori, M Takahashi, P P Zuo, I H Paik, K Kuriyam. Preferential release of newly synthesized [(3)H]GABA from striatal slices to preloaded [(3)H]GABA. Neurochemistry international. vol 6. issue 5. 2012-10-02. PMID:20488090. |
these results suggest that newly synthesized gaba may be preferentially released from its nerve terminals in response to the excitation of neurons at least in the striatum as compared with previously accumulated gaba. |
2012-10-02 |
2023-08-12 |
rat |
| A G Chapman, C L Faingold, G P Hart, H M Bowker, B S Meldru. Brain regional amino acid levels in seizure susceptible rats: Changes related to sound-induced seizures. Neurochemistry international. vol 8. issue 2. 2012-10-02. PMID:20493057. |
other differences include a slight fall in taurine content (in striatum) and an increase in gaba content (in hippocampus). |
2012-10-02 |
2023-08-12 |
rat |
| I Yamada, A Hirata, M Nakahiro, H Yoshid. Endogenous inhibitor of GABA(B) and GABA(A) receptors. Neurochemistry international. vol 10. issue 1. 2012-10-02. PMID:20501083. |
an endogenous inhibitor of ?-aminobutyric acid (gaba) receptors was partially purified from bovine brain striatum. |
2012-10-02 |
2023-08-12 |
cattle |
| T Kuriyama, J Taguchi, K Kuriyam. Functional alterations in striatal cholinergic and striato-nigral gabaergic neurons following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration. Neurochemistry international. vol 16. issue 3. 2012-10-02. PMID:20504575. |
neurochemical changes in cholinergic neurons in the striatum and ?-aminobutyric acid (gaba)ergic neurons in the midbrain, especially in the basal ganglia, have been examined following the intraperitoneal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), which is known to cause behavioral changes resembling those in parkinson's disease due to the destruction of nigro-striatal dopaminergic neurons. |
2012-10-02 |
2023-08-12 |
mouse |
| T Kuriyama, J Taguchi, K Kuriyam. Functional alterations in striatal cholinergic and striato-nigral gabaergic neurons following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration. Neurochemistry international. vol 16. issue 3. 2012-10-02. PMID:20504575. |
although the adminstration of mptp (50 mg/kg, once a day for 5 days) to male mice of dd strain did not induce the changes in choline and acethylcholine contents in the striatum, a decrement of gaba content in the midbrain, especially in the substantia nigra, was found in addition to a significant decrease of dopamine content in the striatum. |
2012-10-02 |
2023-08-12 |
mouse |
| T Kuriyama, J Taguchi, K Kuriyam. Functional alterations in striatal cholinergic and striato-nigral gabaergic neurons following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration. Neurochemistry international. vol 16. issue 3. 2012-10-02. PMID:20504575. |
furthermore, it was found that mptp treatment induced an increase of the gaba(a) receptor-benzodiazepine receptor-chloride channel complex in the substantia nigra in addition to that of dopaminergic d(2) receptor in the striatum. |
2012-10-02 |
2023-08-12 |
mouse |
| S N Schiffmann, J J Vanderhaeghe. Immunocytochemical detection of GABAergic nerve cells in the human striatum and cerebellum using a gamma-aminobutyric acid antiserum. Neurochemistry international. vol 17. issue 1. 2012-10-02. PMID:20504608. |
immunocytochemical detection of gabaergic nerve cells in the human striatum and cerebellum using a gamma-aminobutyric acid antiserum. |
2012-10-02 |
2023-08-12 |
human |
| S N Schiffmann, J J Vanderhaeghe. Immunocytochemical detection of GABAergic nerve cells in the human striatum and cerebellum using a gamma-aminobutyric acid antiserum. Neurochemistry international. vol 17. issue 1. 2012-10-02. PMID:20504608. |
we have adapted the immunocytochemical technique which allows direct detection of gamma-aminobutyric acid (gaba) which has enabled us to visualize gaba-immunoreactive nerve cell bodies, fibers and terminals in post-mortem human striatum and cerebellum. |
2012-10-02 |
2023-08-12 |
human |
| Zhengtao Hu, Yi Deng, Chunyan Hu, Pengchi Deng, Qian Bu, Guangyan Yan, Jiaqing Zhou, Xue Shao, Jinxuan Zhao, Yan Li, Ruiming Zhu, Youzhi Xu, Yinglan Zhao, Xiaobo Ce. ¹H NMR-based metabonomic analysis of brain in rats of morphine dependence and withdrawal intervention. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22391120. |
we found that the concentrations of neurotransmitters including glutamate, glutamine and gamma-aminobutyric acid changed differentially in hippocampus, nac, pfc and striatum after repeated morphine treatment. |
2012-08-20 |
2023-08-12 |
rat |
| Floris G Wouterlood, Wolfgang Härtig, Henk J Groenewegen, Pieter Voor. Density gradients of vesicular glutamate- and GABA transporter-immunoreactive boutons in calbindinand μ-opioid receptor-defined compartments in the rat striatum. The Journal of comparative neurology. vol 520. issue 10. 2012-08-14. PMID:22173881. |
density gradients of vesicular glutamate- and gaba transporter-immunoreactive boutons in calbindinand μ-opioid receptor-defined compartments in the rat striatum. |
2012-08-14 |
2023-08-12 |
rat |
| Floris G Wouterlood, Wolfgang Härtig, Henk J Groenewegen, Pieter Voor. Density gradients of vesicular glutamate- and GABA transporter-immunoreactive boutons in calbindinand μ-opioid receptor-defined compartments in the rat striatum. The Journal of comparative neurology. vol 520. issue 10. 2012-08-14. PMID:22173881. |
we therefore mapped boutons expressing the vesicular glutamate transporters vglut1 and vglut2, together with boutons immunoreactive for vesicular γ-aminobutyric acid (gaba) transporter (vgat) in patch and matrix throughout the striatum. |
2012-08-14 |
2023-08-12 |
rat |
| David J Hinton, Moonnoh R Lee, Taylor L Jacobson, Prasanna K Mishra, Mark A Frye, David A Mrazek, Slobodan I Macura, Doo-Sup Cho. Ethanol withdrawal-induced brain metabolites and the pharmacological effects of acamprosate in mice lacking ENT1. Neuropharmacology. vol 62. issue 8. 2012-08-10. PMID:22616110. |
while the molecular and pharmacological mechanisms of acamprosate remain unclear, it has been shown to regulate γ-aminobutyric acid (gaba) or glutamate levels in the cortex and striatum. |
2012-08-10 |
2023-08-12 |
mouse |
| Flora Mela, Matteo Marti, Simone Bido, M Angela Cenci, Michele Morar. In vivo evidence for a differential contribution of striatal and nigral D1 and D2 receptors to L-DOPA induced dyskinesia and the accompanying surge of nigral amino acid levels. Neurobiology of disease. vol 45. issue 1. 2012-07-23. PMID:22001605. |
in addition, the stimulation of nigral d2 receptors contributes to dyskinesia while modulating glutamate and gaba efflux both locally and in the striatum. |
2012-07-23 |
2023-08-12 |
rat |
| Shunsuke Tanahashi, Yuto Ueda, Akira Nakajima, Satoshi Yamamura, Hiroshi Nagase, Motohiro Okad. Novel δ1-receptor agonist KNT-127 increases the release of dopamine and L-glutamate in the striatum, nucleus accumbens and median pre-frontal cortex. Neuropharmacology. vol 62. issue 5-6. 2012-07-23. PMID:22266218. |
to clarify the functional selectivity of knt-127 and neurotransmission regulating system of δ1-receptor, the present study investigated the interaction between knt-127 and δ-receptor antagonists on the release of dopamine, l-glutamate and gaba in nucleus accumbens (nac), striatum and median pre-frontal cortex (mpfc) using multi-probe microdialysis. |
2012-07-23 |
2023-08-12 |
Not clear |
| Shunsuke Tanahashi, Yuto Ueda, Akira Nakajima, Satoshi Yamamura, Hiroshi Nagase, Motohiro Okad. Novel δ1-receptor agonist KNT-127 increases the release of dopamine and L-glutamate in the striatum, nucleus accumbens and median pre-frontal cortex. Neuropharmacology. vol 62. issue 5-6. 2012-07-23. PMID:22266218. |
intraperitoneal administration of knt-127 increased the release of dopamine and l-glutamate in three regions, but decreased and increased gaba releases in respective nac and mpfc without affecting that in striatum. |
2012-07-23 |
2023-08-12 |
Not clear |