| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Louise Adermark, Rhona B C Clarke, Mia Ericson, Bo Söderpal. Subregion-Specific Modulation of Excitatory Input and Dopaminergic Output in the Striatum by Tonically Activated Glycine and GABA(A) Receptors. Frontiers in systems neuroscience. vol 5. 2011-11-10. PMID:22028683. |
strychnine-induced disinhibition of glutamatergic transmission was insensitive to the muscarinic receptor inhibitor scopolamine (10 μm), inhibited by the nicotinic acetylcholine receptor antagonist mecamylamine (10 μm) and blocked by gaba(a) receptor inhibitors, suggesting that tonically activated glycine receptors depress excitatory input to the striatum through modulation of cholinergic and gabaergic neurotransmission. |
2011-11-10 |
2023-08-12 |
rat |
| Silvia Rossi, Luca Muzio, Valentina De Chiara, Giorgio Grasselli, Alessandra Musella, Gabriele Musumeci, Georgia Mandolesi, Roberta De Ceglia, Simona Maida, Emilia Biffi, Alessandra Pedrocchi, Andrea Menegon, Giorgio Bernardi, Roberto Furlan, Gianvito Martino, Diego Centonz. Impaired striatal GABA transmission in experimental autoimmune encephalomyelitis. Brain, behavior, and immunity. vol 25. issue 5. 2011-10-12. PMID:20940040. |
while excessive glutamate signaling has been reported in the striatum of eae, it is still uncertain whether gaba synapses are altered. |
2011-10-12 |
2023-08-12 |
mouse |
| Roberto Romero González, Remedios Fernández Fernández, José Luis Martínez Vidal, Antonia Garrido Frenich, María Luz Gómez Pére. Development and validation of an ultra-high performance liquid chromatography-tandem mass-spectrometry (UHPLC-MS/MS) method for the simultaneous determination of neurotransmitters in rat brain samples. Journal of neuroscience methods. vol 198. issue 2. 2011-10-07. PMID:21459108. |
therefore, the method was successfully applied for the quantitative determination of neurotransmitters in several rat brain regions (prefrontal cortex, striatum, nucleus accumbens and amygdala), detecting glutamate, gaba and choline at concentrations higher than 1000 μg/g, 30 μg/g and 100 μg/g respectively, whereas the other compounds were found at lower concentrations. |
2011-10-07 |
2023-08-12 |
rat |
| Steve C Fordahl, Joel G Anderson, Paula T Cooney, Tara L Weaver, Christa L Colyer, Keith M Erikso. Manganese exposure inhibits the clearance of extracellular GABA and influences taurine homeostasis in the striatum of developing rats. Neurotoxicology. vol 31. issue 6. 2011-09-29. PMID:20832424. |
manganese exposure inhibits the clearance of extracellular gaba and influences taurine homeostasis in the striatum of developing rats. |
2011-09-29 |
2023-08-12 |
rat |
| Steve C Fordahl, Joel G Anderson, Paula T Cooney, Tara L Weaver, Christa L Colyer, Keith M Erikso. Manganese exposure inhibits the clearance of extracellular GABA and influences taurine homeostasis in the striatum of developing rats. Neurotoxicology. vol 31. issue 6. 2011-09-29. PMID:20832424. |
extracellular gaba, taurine, and glycine concentrations were collected from the striatum of control (cn) or mn-exposed sprague-dawley rats using in vivo microdialysis, and the gat inhibitor nipecotic acid (na) was used to probe gat function. |
2011-09-29 |
2023-08-12 |
rat |
| Nerea Moreno, Ruth Morona, Jesús M López, Agustín Gonzále. Subdivisions of the turtle Pseudemys scripta subpallium based on the expression of regulatory genes and neuronal markers. The Journal of comparative neurology. vol 518. issue 24. 2011-09-12. PMID:21031557. |
in the basal ganglia, the combinatorial expression on pax6, nkx2.1, and gaba was a powerful tool for the identification of the nucleus accumbens, the dorsal portion of the striatum, and the pallidal regions. |
2011-09-12 |
2023-08-12 |
Not clear |
| Chia-Ying Chuang, Yeu-Ching Shi, He-Pei You, Yi-Hiyuan Lo, Tzu-Ming Pa. Antidepressant effect of GABA-rich monascus-fermented product on forced swimming rat model. Journal of agricultural and food chemistry. vol 59. issue 7. 2011-08-17. PMID:21375324. |
in addition to the functions of gaba, the mfp has more potential in decreasing the turnover ratio of da in the frontal cortex and striatum to improve depressive symptoms. |
2011-08-17 |
2023-08-12 |
rat |
| B Lin, S Levy, A P Raval, M A Perez-Pinzon, R A Defazi. Forebrain ischemia triggers GABAergic system degeneration in substantia nigra at chronic stages in rats. Cardiovascular psychiatry and neurology. vol 2010. 2011-07-14. PMID:20981346. |
following neuronal loss of 30-40% in central and dorsolateral striatum at day 3, neuronal damage in the substantia nigra (sn) was assessed at 4-8 weeks using immunohistochemistry for glutamate decarboxylase 67 (gad67), vesicular gaba transporter (vgat), and calretinin (cr). |
2011-07-14 |
2023-08-12 |
rat |
| Letaïef Rekik, Véronique Daguin-Nerrière, Jean-Yves Petit, Philippe Brache. γ-Aminobutyric acid type B receptor changes in the rat striatum and substantia nigra following intrastriatal quinolinic acid lesions. Journal of neuroscience research. vol 89. issue 4. 2011-06-10. PMID:21290407. |
animals received a unilateral intrastriatal injection of quinolinic acid (qa), and gaba(b) immunoreactivity was monitored 3, 11, and 21 days postinjection in the striatum and substantia nigra (sn). |
2011-06-10 |
2023-08-12 |
rat |
| Letaïef Rekik, Véronique Daguin-Nerrière, Jean-Yves Petit, Philippe Brache. γ-Aminobutyric acid type B receptor changes in the rat striatum and substantia nigra following intrastriatal quinolinic acid lesions. Journal of neuroscience research. vol 89. issue 4. 2011-06-10. PMID:21290407. |
qa injection rapidly induced a protracted increase in gaba(b1) or gaba(b2) immunoreactivity in the lesioned striatum, despite the neuronal loss. |
2011-06-10 |
2023-08-12 |
rat |
| Letaïef Rekik, Véronique Daguin-Nerrière, Jean-Yves Petit, Philippe Brache. γ-Aminobutyric acid type B receptor changes in the rat striatum and substantia nigra following intrastriatal quinolinic acid lesions. Journal of neuroscience research. vol 89. issue 4. 2011-06-10. PMID:21290407. |
hence, part of the sustained increase in gaba(b) immunoreactivity that takes place in the snr and possibly the striatum may be ascribed to reactive astrocytes. |
2011-06-10 |
2023-08-12 |
rat |
| Nao Chuhma, Kenji F Tanaka, René Hen, Stephen Raypor. Functional connectome of the striatal medium spiny neuron. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 4. 2011-03-30. PMID:21273403. |
in the striatum, medium spiny neurons connected with other msns and tonically active cholinergic interneurons, but not with fast-spiking gaba interneurons. |
2011-03-30 |
2023-08-12 |
mouse |
| Yan Li, Glenn Dave Blanco, Zhigang Lei, Zao Cheng X. Increased GAD expression in the striatum after transient cerebral ischemia. Molecular and cellular neurosciences. vol 45. issue 4. 2011-02-07. PMID:20659561. |
immunohistochemical studies and western blotting were performed to examine the expression of glutamic decarboxylase (gad), the key enzyme in the synthesis of gaba, in the striatum. |
2011-02-07 |
2023-08-12 |
Not clear |
| Yan Li, Glenn Dave Blanco, Zhigang Lei, Zao Cheng X. Increased GAD expression in the striatum after transient cerebral ischemia. Molecular and cellular neurosciences. vol 45. issue 4. 2011-02-07. PMID:20659561. |
facilitation of inhibitory synaptic transmission by muscimol, a specific gaba(a) receptor agonist, increased the number of survived cells in the striatum after ischemia. |
2011-02-07 |
2023-08-12 |
Not clear |
| Priscila Gubert, Daiana Silva Avila, Jessika Cristina Bridi, Sara Saurin, Thiago Henrique Lugokenski, Jardel Gomes Villarinho, Roselei Fachinetto, Maria Ester Pereira, Juliano Ferreira, João Batista Teixeira da Rocha, Félix Alexandre Antunes Soare. Low concentrations of methamidophos do not alter AChE activity but modulate neurotransmitters uptake in hippocampus and striatum in vitro. Life sciences. vol 88. issue 1-2. 2011-01-21. PMID:21075126. |
as the mechanism of its neurotoxic effects is not well understood, the aim of the present study was to evaluate the effects of meth on glutamate and gamma aminobutyric acid (gaba) uptake and correlate with cell viability and ache and na(+)/k(+)-atpase enzyme activities in striatum and hippocampus slices exposed to low concentrations (0.05 to 1.0 μm) of meth. |
2011-01-21 |
2023-08-12 |
Not clear |
| A Amritraj, G Rauw, G B Baker, S Ka. Leu27 insulin-like growth factor-II, an insulin-like growth factor-II analog, attenuates depolarization-evoked GABA release from adult rat hippocampal and cortical slices. Neuroscience. vol 170. issue 3. 2011-01-11. PMID:20659530. |
additionally, leu(27)igf-ii was found to attenuate gaba release from frontal cortex but not from striatum. |
2011-01-11 |
2023-08-12 |
rat |
| Jobin Mathew, Smijin Soman, Jayanarayanan Sadanandan, Cheramadathikudyil Skaria Paulos. Decreased GABA receptor in the striatum and spatial recognition memory deficit in epileptic rats: effect of Bacopa monnieri and bacoside-A. Journal of ethnopharmacology. vol 130. issue 2. 2010-11-04. PMID:20451596. |
decreased gaba receptor in the striatum and spatial recognition memory deficit in epileptic rats: effect of bacopa monnieri and bacoside-a. |
2010-11-04 |
2023-08-12 |
rat |
| Jobin Mathew, Smijin Soman, Jayanarayanan Sadanandan, Cheramadathikudyil Skaria Paulos. Decreased GABA receptor in the striatum and spatial recognition memory deficit in epileptic rats: effect of Bacopa monnieri and bacoside-A. Journal of ethnopharmacology. vol 130. issue 2. 2010-11-04. PMID:20451596. |
gamma-aminobutyric acid a receptors are the principal mediators of synaptic inhibition in striatal neurons and play an important role in preventing the spreading of seizures through the striatum. |
2010-11-04 |
2023-08-12 |
rat |
| Jobin Mathew, Smijin Soman, Jayanarayanan Sadanandan, Cheramadathikudyil Skaria Paulos. Decreased GABA receptor in the striatum and spatial recognition memory deficit in epileptic rats: effect of Bacopa monnieri and bacoside-A. Journal of ethnopharmacology. vol 130. issue 2. 2010-11-04. PMID:20451596. |
in the present study, effect of bacopa monnieri (l.) pennel and its active component bacoside-a on spatial recognition memory deficit and alterations of gaba receptor in the striatum of epileptic rats were investigated. |
2010-11-04 |
2023-08-12 |
rat |
| Carine Chassain, Guy Bielicki, Cécile Keller, Jean-Pierre Renou, Franck Duri. Metabolic changes detected in vivo by 1H MRS in the MPTP-intoxicated mouse. NMR in biomedicine. vol 23. issue 6. 2010-11-04. PMID:20661872. |
we used in vivo proton ((1)h) magnetic resonance spectroscopy (mrs) to measure the levels of the main excitatory amino acid, glutamate (glu) and also glutamine (gln) and gaba in the striatum and cerebral cortex in the mptp-intoxicated mouse, a model of dopaminergic denervation, before and after dopamine (da) replacement. |
2010-11-04 |
2023-08-12 |
mouse |