| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marc W Nolte, Wolfgang Löscher, Christiane Herden, William J Freed, Manuela Gerner. Benefits and risks of intranigral transplantation of GABA-producing cells subsequent to the establishment of kindling-induced seizures. Neurobiology of disease. vol 31. issue 3. 2008-12-15. PMID:18632280. |
three cell lines were transplanted: (1) immortalized gabaergic cells (m213-2o) derived from embryonic rat striatum; (2) m213-2o cells (cl4) transfected with human gad67 cdna to obtain higher gaba synthesis than the parent cell line; and (3) control cells (121-1i), also derived from embryonic rat striatum, but which did not show gad expression. |
2008-12-15 |
2023-08-12 |
human |
| Elena Brazhnik, Fulva Shah, James M Teppe. GABAergic afferents activate both GABAA and GABAB receptors in mouse substantia nigra dopaminergic neurons in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 41. 2008-11-03. PMID:18842898. |
inhibitory responses of rat nigral dopaminergic neurons by stimulation of afferents from striatum, globus pallidus, or pars reticulata have been shown to be mediated predominantly or exclusively by gaba(a) receptors. |
2008-11-03 |
2023-08-12 |
mouse |
| Kazushi Miya, Ran Inoue, Yoshimi Takata, Manabu Abe, Rie Natsume, Kenji Sakimura, Kazuhisa Hongou, Toshio Miyawaki, Hisashi Mor. Serine racemase is predominantly localized in neurons in mouse brain. The Journal of comparative neurology. vol 510. issue 6. 2008-10-27. PMID:18698599. |
in the striatum, we observed sr expression in gamma-aminobutyric acid (gaba)ergic medium-spiny neurons. |
2008-10-27 |
2023-08-12 |
mouse |
| E B Shubenina, V S Kudrin, P M Klodt, A A Pokrovskiĭ, T A Gudasheva, T A Voronina, R U Ostrovskai. [Interstrain differences in the content of excitatory and inhibitory amino acids in the brain of DBA/2J, Balb/c and C57BL/6 mice: characteristics of the effect of a dipeptide antipsychotic drug dilept]. Eksperimental'naia i klinicheskaia farmakologiia. vol 71. issue 4. 2008-10-27. PMID:18819433. |
we have performed a comparative study of the content of glutamate (glu), aspartate (asp), taurine (tau), glycine (gly) and gamma-amino-butyric acid (gaba) in the cortex, hippocampus, and striatum of the dba/2j, balb/c and c57bl/6 mice brain. |
2008-10-27 |
2023-08-12 |
mouse |
| E B Shubenina, V S Kudrin, P M Klodt, A A Pokrovskiĭ, T A Gudasheva, T A Voronina, R U Ostrovskai. [Interstrain differences in the content of excitatory and inhibitory amino acids in the brain of DBA/2J, Balb/c and C57BL/6 mice: characteristics of the effect of a dipeptide antipsychotic drug dilept]. Eksperimental'naia i klinicheskaia farmakologiia. vol 71. issue 4. 2008-10-27. PMID:18819433. |
dilept induced a statistically significant increase in the levels of glu, tau and gaba in striatum of dba/2j, as well as insignificant increase in the levels of these amino acids in the cortex. |
2008-10-27 |
2023-08-12 |
mouse |
| Carrie L Heusner, Lisa R Beutler, Carolyn R Houser, Richard D Palmite. Deletion of GAD67 in dopamine receptor-1 expressing cells causes specific motor deficits. Genesis (New York, N.Y. : 2000). vol 46. issue 7. 2008-09-22. PMID:18615733. |
the medium spiny neurons (msns), which comprise the direct and indirect output pathways from the striatum, use gamma-aminobutyric acid (gaba) as their major fact-acting neurotransmitter. |
2008-09-22 |
2023-08-12 |
mouse |
| Carrie L Heusner, Lisa R Beutler, Carolyn R Houser, Richard D Palmite. Deletion of GAD67 in dopamine receptor-1 expressing cells causes specific motor deficits. Genesis (New York, N.Y. : 2000). vol 46. issue 7. 2008-09-22. PMID:18615733. |
we generated mice carrying a conditional allele of the gad1 gene, which encodes gad67, one of the two enzymes responsible for gaba biosynthesis, and bred them to mice expressing cre recombinase at the dopamine d1 receptor locus (drd1a) to selectively reduce gaba synthesis in the direct output pathway from the striatum. |
2008-09-22 |
2023-08-12 |
mouse |
| Martina Fantin, Yves P Auberson, Michele Morar. Differential effect of NR2A and NR2B subunit selective NMDA receptor antagonists on striato-pallidal neurons: relationship to motor response in the 6-hydroxydopamine model of parkinsonism. Journal of neurochemistry. vol 106. issue 2. 2008-09-16. PMID:18435828. |
the nr2a antagonist nvp-aam077 perfused in the striatum reduced pallidal gaba, but not glutamate, levels whereas the nr2b antagonist ro 25-6981 was ineffective. |
2008-09-16 |
2023-08-12 |
rat |
| Peter G Osborne, Masaaki Hashimot. Mammalian cerebral metabolism and amino acid neurotransmission during hibernation. Journal of neurochemistry. vol 106. issue 4. 2008-09-12. PMID:18624914. |
microdialysis of (14)c glucose into the striatum rapidly induced a steady state labeling of extracellular fluid (ecf) lactate and labeling of tissue gaba, glutamate, glutamine, and alanine in ipsilateral and contralateral striata. |
2008-09-12 |
2023-08-12 |
Not clear |
| N Yamamoto, J-J Soghomonia. Time-course of SKF-81297-induced increase in glutamic acid decarboxylase 65 and 67 mRNA levels in striatonigral neurons and decrease in GABA(A) receptor alpha1 subunit mRNA levels in the substantia nigra, pars reticulata, in adult rats with a unilateral 6-hydroxydopamine lesion. Neuroscience. vol 154. issue 3. 2008-08-29. PMID:18495353. |
in the present study, the effects of a single or subchronic systemic administration of the dopamine d1/d5-preferring receptor agonist skf-81297 on gad65, gad67, ppd and vgat mrna levels in the striatum and gaba(a) receptor alpha1 subunit mrna levels in the substantia nigra, pars reticulata, were measured in rats with a unilateral 6-hydroxydopamine (6-ohda) lesion. |
2008-08-29 |
2023-08-12 |
rat |
| N Yamamoto, J-J Soghomonia. Time-course of SKF-81297-induced increase in glutamic acid decarboxylase 65 and 67 mRNA levels in striatonigral neurons and decrease in GABA(A) receptor alpha1 subunit mRNA levels in the substantia nigra, pars reticulata, in adult rats with a unilateral 6-hydroxydopamine lesion. Neuroscience. vol 154. issue 3. 2008-08-29. PMID:18495353. |
they also suggest that the down-regulation of nigral gaba(a) receptors is linked to the increase in striatal gad67 mrna levels in the dopamine-depleted striatum. |
2008-08-29 |
2023-08-12 |
rat |
| Beibei Wang, Xifeng Zou, Haiyan Zhang, Deyi Duan, Lili Ju, Xiaohua Jiang, Xiaohong Sun, Chunli Zhao, Huanying Zhao, Jin Guo, Changlei Xu, Erjing Gao, Qunyuan X. Establishment of an immortalized GABAergic neuronal progenitor cell line from embryonic ventral mesencephalon in the rat. Brain research. vol 1210. 2008-08-26. PMID:18407253. |
the cells survived well and kept expression of sv40 tag, gad65/67 and gaba in the striatum, at least 28 days after being transplanted in the rat brain. |
2008-08-26 |
2023-08-12 |
rat |
| Chiko Shinbori, Yukihiko Shirayama, Hideaki Mitani, Motoaki Saito, Keisuke Sato. Effects of cyclohexanonic long-chain fatty alcohol, tCFA15 on amino acids in diabetic rat brain: a preliminary study. Neurochemical research. vol 33. issue 7. 2008-08-20. PMID:18338258. |
the aim of this study was to evaluate the effects of streptozotocin-induced type 1diabetes and a subchronic treatment with cyclohexanonic long-chain fatty alcohol, 3-(15-hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen 1-one (tcfa15) on contents of amino acids including aspartate, glutamate, glutamine, gaba, glycine, taurine, alanine, serine, threonine, and arginine in the prefrontal cortex, hippocampus and striatum. |
2008-08-20 |
2023-08-12 |
rat |
| Silvia Rossi, Valentina De Chiara, Alessandra Musella, Hajime Kusayanagi, Giorgia Mataluni, Giorgio Bernardi, Alessandro Usiello, Diego Centonz. Chronic psychoemotional stress impairs cannabinoid-receptor-mediated control of GABA transmission in the striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 29. 2008-08-12. PMID:18632932. |
chronic psychoemotional stress impairs cannabinoid-receptor-mediated control of gaba transmission in the striatum. |
2008-08-12 |
2023-08-12 |
mouse |
| Lee E Schechter, Qian Lin, Deborah L Smith, Guoming Zhang, Qin Shan, Brian Platt, Michael R Brandt, Lee A Dawson, Derek Cole, Ron Bernotas, Albert Robichaud, Sharon Rosenzweig-Lipson, Chad E Beye. Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 6. 2008-08-07. PMID:17625499. |
in the dorsal hippocampus, striatum, and amygdala, way-181187 (10-30 mg/kg, s.c.) elicited robust elevations in extracellular levels of gaba without producing similar effects on concentrations of norepinephrine, serotonin, dopamine, or glutamate. |
2008-08-07 |
2023-08-12 |
human |
| Svetlana M Molchanova, Simos S Oja, Pirjo Saransaar. Effect of taurine on the concentrations of glutamate, GABA, glutamine and alanine in the rat striatum and hippocampus. Proceedings of the Western Pharmacology Society. vol 50. 2008-07-31. PMID:18605241. |
effect of taurine on the concentrations of glutamate, gaba, glutamine and alanine in the rat striatum and hippocampus. |
2008-07-31 |
2023-08-12 |
rat |
| Svetlana M Molchanova, Simos S Oja, Pirjo Saransaar. Effect of taurine on the concentrations of glutamate, GABA, glutamine and alanine in the rat striatum and hippocampus. Proceedings of the Western Pharmacology Society. vol 50. 2008-07-31. PMID:18605241. |
here we studied the effects of intraperitoneal injections of taurine on the concentrations of glutamate and gaba, and their precursors, glutamine and alanine, in the rat striatum and hippocampus. |
2008-07-31 |
2023-08-12 |
rat |
| Svetlana M Molchanova, Simos S Oja, Pirjo Saransaar. Effect of taurine on the concentrations of glutamate, GABA, glutamine and alanine in the rat striatum and hippocampus. Proceedings of the Western Pharmacology Society. vol 50. 2008-07-31. PMID:18605241. |
glutamate and gaba also increased in the hippocampus, but not in the striatum. |
2008-07-31 |
2023-08-12 |
rat |
| M Sakuma, N Hyakawa, H Kato, T Arak. Time dependent changes of striatal interneurons after focal cerebral ischemia in rats. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 3. 2008-07-01. PMID:18301954. |
we investigated the immunohistochemical alterations of choline acetyltransferase (chat)-positive (cholinergic-positive), gamma-aminobutyric acid (gaba)ergic parvalbumin (pv)-positive, gabaergic nnos (neuronal nitric oxide synthase)-positive interneurons, neuronal nuclei (neun)-positive spiny projection neurons, glial fibrillary acidic protein (gfap)-positive strocytes and microglial response factor-1 (mrf-1)-positive microglia in the striatum after focal cerebral ischemia in rats. |
2008-07-01 |
2023-08-12 |
rat |
| Diego Centonze, Silvia Rossi, Paola De Bartolo, Valentina De Chiara, Francesca Foti, Alessandra Musella, Giorgia Mataluni, Stefano Rossi, Giorgio Bernardi, Giacomo Koch, Laura Petrosin. Adaptations of glutamatergic synapses in the striatum contribute to recovery from cerebellar damage. The European journal of neuroscience. vol 27. issue 8. 2008-07-01. PMID:18412636. |
hemicerebellectomy also perturbed gamma-aminobutyric acid (gaba) transmission in contralateral but not ipsilateral striatum. |
2008-07-01 |
2023-08-12 |
rat |