| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carine Chassain, Guy Bielicki, Cécile Keller, Jean-Pierre Renou, Franck Duri. Metabolic changes detected in vivo by 1H MRS in the MPTP-intoxicated mouse. NMR in biomedicine. vol 23. issue 6. 2010-11-04. PMID:20661872. |
glu, gln and gaba concentrations obtained in the basal state were significantly increased in the striatum of mptp-lesioned mice (glu: 20.2 +/- 0.8 vs 11.4 +/- 0.9 mm, p < 0.001; gln: 5.4 +/- 1.6 vs 2.0 +/- 0.6 mm, p < 0.05; gaba: 3.6 +/- 0.8 vs 1.6 +/- 0.2 mm, p < 0.05). |
2010-11-04 |
2023-08-12 |
mouse |
| Carine Chassain, Guy Bielicki, Cécile Keller, Jean-Pierre Renou, Franck Duri. Metabolic changes detected in vivo by 1H MRS in the MPTP-intoxicated mouse. NMR in biomedicine. vol 23. issue 6. 2010-11-04. PMID:20661872. |
levodopa lowered metabolites concentrations in the striatum of mptp-lesioned mice (glu: 20.2 +/- 0.8 vs 11.2 +/- 0.4 mm (+ ldopa), p < 0.001; gln: 5.4 +/- 1.6 vs 1.6 +/- 0.4 mm (+ ldopa), p < 0.05; gaba: 3.6 +/- 0.8 vs 1.7 +/- 0.4 mm (+ ldopa), p < 0.01). |
2010-11-04 |
2023-08-12 |
mouse |
| B Fernández-Pérez, A Caride, T Cabaleiro, A Lafuent. Cadmium effects on 24h changes in glutamate, aspartate, glutamine, GABA and taurine content of rat striatum. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 24. issue 3. 2010-09-15. PMID:20569935. |
cadmium effects on 24h changes in glutamate, aspartate, glutamine, gaba and taurine content of rat striatum. |
2010-09-15 |
2023-08-12 |
rat |
| Jie Wang, Lihong Jiang, Yifeng Jiang, Xiaoxian Ma, Golam M I Chowdhury, Graeme F Maso. Regional metabolite levels and turnover in the awake rat brain under the influence of nicotine. Journal of neurochemistry. vol 113. issue 6. 2010-08-06. PMID:20345764. |
nicotine was observed to exert significant effects on the concentrations of n-acetylaspartate and gaba, particularly in the striatum. |
2010-08-06 |
2023-08-12 |
rat |
| Jie Wang, Lihong Jiang, Yifeng Jiang, Xiaoxian Ma, Golam M I Chowdhury, Graeme F Maso. Regional metabolite levels and turnover in the awake rat brain under the influence of nicotine. Journal of neurochemistry. vol 113. issue 6. 2010-08-06. PMID:20345764. |
nicotine decreased brain glucose oxidation, glutamate-glutamine neurotransmitter cycling, and gaba synthesis regionally, including in the parietal and occipital cortices and the striatum. |
2010-08-06 |
2023-08-12 |
rat |
| Robert I Westphalen, Jieying Yu, Margarita Krivitski, Ting-Yu Jih, Hugh C Hemming. Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS. Journal of neurochemistry. vol 113. issue 6. 2010-08-06. PMID:20374421. |
na(v) coupling to transmitter release was determined by measuring the sensitivity of 4-aminopyridine (4ap)-evoked [(3)h]glutamate and [(14)c]gaba release to the specific na(v) blocker tetrodotoxin (ttx) for nerve terminals isolated from rat cerebral cortex, hippocampus, striatum and spinal cord. |
2010-08-06 |
2023-08-12 |
rat |
| Silvia Rossi, Valentina De Chiara, Alessandra Musella, Lucia Sacchetti, Cristina Cantarella, Maura Castelli, Francesca Cavasinni, Caterina Motta, Valeria Studer, Giorgio Bernardi, Benjamin F Cravatt, Mauro Maccarrone, Alessandro Usiello, Diego Centonz. Preservation of striatal cannabinoid CB1 receptor function correlates with the antianxiety effects of fatty acid amide hydrolase inhibition. Molecular pharmacology. vol 78. issue 2. 2010-08-03. PMID:20424126. |
this behavioral effect was associated with preserved activity of cb1rs regulating gaba transmission in the striatum, whereas these receptors were dramatically down-regulated by stress in control animals. |
2010-08-03 |
2023-08-12 |
mouse |
| Zhimin Li, Yanqi Liang, Mona Boules, Andres Gordillo, Elliott Richelso. Effect of amphetamine on extracellular concentrations of amino acids in striatum in neurotensin subtype 1 and 2 receptor null mice: a possible interaction between neurotensin receptors and amino acid systems for study of schizophrenia. Neuropharmacology. vol 58. issue 7. 2010-07-19. PMID:20193696. |
therefore, nts1 and nts2 modulate basal release of d-serine and glutamate, and also d-amphetamine-induced gaba and glutamate release in striatum. |
2010-07-19 |
2023-08-12 |
mouse |
| Orhan Tansel Korkmaz, Neşe Tunçel, Muzaffer Tunçel, Elif Mine Oncü, Varol Sahintürk, Mustafa Celi. Vasoactive intestinal peptide (VIP) treatment of Parkinsonian rats increases thalamic gamma-aminobutyric acid (GABA) levels and alters the release of nerve growth factor (NGF) by mast cells. Journal of molecular neuroscience : MN. vol 41. issue 2. 2010-07-09. PMID:19953344. |
was investigated on gaba levels of the vath, dopamine/3,4-dihydroxyphenylacetic acid (dopac) levels in the corpus striatum, and the ngf, rat mast cell protease ii (rmcpii), serotonin, and heparin content of brain mast cells in 6-ohda-lesioned rats. |
2010-07-09 |
2023-08-12 |
rat |
| Mauro Maccarrone, Silvia Rossi, Monica Bari, Valentina De Chiara, Cinzia Rapino, Alessandra Musella, Giorgio Bernardi, Claudia Bagni, Diego Centonz. Abnormal mGlu 5 receptor/endocannabinoid coupling in mice lacking FMRP and BC1 RNA. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 7. 2010-07-09. PMID:20393458. |
in the striatum of mice lacking fmrp, we found enhanced activity of diacylglycerol lipase (dagl), the enzyme limiting 2-arachidonoylglicerol (2-ag) synthesis, associated with altered sensitivity of gaba synapses to the mobilization of this endocannabinoid by mglu5r stimulation with dhpg. |
2010-07-09 |
2023-08-12 |
mouse |
| V Santhakumar, R T Jones, I Mod. Developmental regulation and neuroprotective effects of striatal tonic GABAA currents. Neuroscience. vol 167. issue 3. 2010-06-29. PMID:20206233. |
our data are consistent with a role for tonic inhibition mediated by gaba(a)r delta subunits in neuroprotection against excitotoxic insults in the adult striatum. |
2010-06-29 |
2023-08-12 |
mouse |
| Farhad Ghoddoussi, Matthew P Galloway, Amruta Jambekar, Monica Bame, Richard Needleman, William S A Brusilo. Methionine sulfoximine, an inhibitor of glutamine synthetase, lowers brain glutamine and glutamate in a mouse model of ALS. Journal of the neurological sciences. vol 290. issue 1-2. 2010-05-13. PMID:20060132. |
proton magnetic resonance spectroscopy, with magic angle spinning of intact samples of brain tissue, showed that mso treatment reduced brain levels of glutamine by 60% and of glutamate by 30% in both the motor cortex and the anterior striatum, while also affecting levels of gaba and glutathione. |
2010-05-13 |
2023-08-12 |
mouse |
| Harald D Müller, Christian Berger, Stefan Schwab, Clemens Somme. Pravastatin treatment causes a shift in the balance of hippocampal neurotransmitter binding densities towards inhibition. Brain research. vol 1316. 2010-05-06. PMID:20026313. |
using quantitative receptor autoradiography, ligand binding densities of [(3)h]mk-801, [(3)h]ampa, and [(3)h]muscimol for labeling of nmda, ampa, and gaba(a) receptors were analyzed in sensorimotor cortices par1 and par2, the striatum, and the hippocampus. |
2010-05-06 |
2023-08-12 |
rat |
| Harald D Müller, Christian Berger, Stefan Schwab, Clemens Somme. Pravastatin treatment causes a shift in the balance of hippocampal neurotransmitter binding densities towards inhibition. Brain research. vol 1316. 2010-05-06. PMID:20026313. |
within the striatum, ampa as well as gaba(a) receptor binding values were significantly increased on day 5. |
2010-05-06 |
2023-08-12 |
rat |
| K Buck, P Voehringer, B Ferge. Site-specific action of L-3,4-dihydroxyphenylalanine in the striatum but not globus pallidus and substantia nigra pars reticulata evokes dyskinetic movements in chronic L-3,4-dihydroxyphenylalanine-treated 6-hydroxydopamine-lesioned rats. Neuroscience. vol 166. issue 2. 2010-05-03. PMID:20026252. |
we have investigated the effect of an acute and local administration of l-dopa, gaba and glutamate to provoke dyskinetic movements in three basal ganglia structures (striatum, globus pallidus (gp) and substantia nigra pars reticulata (snr)) of chronically l-dopa-treated, unilaterally 6-hydroxydopamine-lesioned rats. |
2010-05-03 |
2023-08-12 |
rat |
| K Buck, P Voehringer, B Ferge. Site-specific action of L-3,4-dihydroxyphenylalanine in the striatum but not globus pallidus and substantia nigra pars reticulata evokes dyskinetic movements in chronic L-3,4-dihydroxyphenylalanine-treated 6-hydroxydopamine-lesioned rats. Neuroscience. vol 166. issue 2. 2010-05-03. PMID:20026252. |
neither gaba nor glutamate triggered dyskinetic movements in the striatum, gp or snr. |
2010-05-03 |
2023-08-12 |
rat |
| Eduardo A Schilman, Oded Klavir, Christine Winter, Reinhard Sohr, Daphna Joe. The role of the striatum in compulsive behavior in intact and orbitofrontal-cortex-lesioned rats: possible involvement of the serotonergic system. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 4. 2010-04-28. PMID:20072118. |
experiment 1 revealed that ofc lesions decrease the content of serotonin, dopamine, glutamate, and gaba in the striatum. |
2010-04-28 |
2023-08-12 |
rat |
| G Govindaiah, Yanyan Wang, Charles L Co. Substance P selectively modulates GABA(A) receptor-mediated synaptic transmission in striatal cholinergic interneurons. Neuropharmacology. vol 58. issue 2. 2010-04-13. PMID:19786036. |
substance p (sp) is co-localized and co-released with gamma-amino butyric acid (gaba) from approximately 50% of gabaergic medium spiny neurons (msns) in the striatum. |
2010-04-13 |
2023-08-12 |
mouse |
| H Haghir, S Kovac, E-J Speckmann, K Zilles, A Gorj. Patterns of neurotransmitter receptor distributions following cortical spreading depression. Neuroscience. vol 163. issue 4. 2010-02-12. PMID:19665048. |
cortical sd also upregulated nmda, ampa, kainate, gaba(a), serotonergic 5-ht(2), adrenergic alpha(2) and dopaminergic d1 receptor binding sites in the striatum. |
2010-02-12 |
2023-08-12 |
rat |
| Shonagh K O'Leary-Moore, Matthew P Galloway, Andrew P McMechan, Susan Irtenkauf, John H Hannigan, Scott E Bowe. Neurochemical changes after acute binge toluene inhalation in adolescent and adult rats: a high-resolution magnetic resonance spectroscopy study. Neurotoxicology and teratology. vol 31. issue 6. 2010-01-07. PMID:19628036. |
in contrast to these minimal effects in adolescents, binge toluene exposure altered several neurochemical parameters in young adult rats, including decreased levels of choline and gaba in the frontal cortex and striatum and lowered glutamine and naa levels in the frontal cortex. |
2010-01-07 |
2023-08-12 |
rat |