| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K L Brickell, L F Nicholson, H J Waldvogel, R L Faul. Chemical and anatomical changes in the striatum and substantia nigra following quinolinic acid lesions in the striatum of the rat: a detailed time course of the cellular and GABA(A) receptor changes. Journal of chemical neuroanatomy. vol 17. issue 2. 1999-12-15. PMID:10585160. |
chemical and anatomical changes in the striatum and substantia nigra following quinolinic acid lesions in the striatum of the rat: a detailed time course of the cellular and gaba(a) receptor changes. |
1999-12-15 |
2023-08-12 |
rat |
| K L Brickell, L F Nicholson, H J Waldvogel, R L Faul. Chemical and anatomical changes in the striatum and substantia nigra following quinolinic acid lesions in the striatum of the rat: a detailed time course of the cellular and GABA(A) receptor changes. Journal of chemical neuroanatomy. vol 17. issue 2. 1999-12-15. PMID:10585160. |
this study shows that following quinolinic acid lesions of the striatum there is a major loss of calbindin and somatostatin/neuropeptide y immunoreactive cells in the striatum within 24 h, and a marked increase in gaba(a) receptors in the substantia nigra within 2 h. these findings are similar to the changes in the basal ganglia in huntington's disease and provide further evidence supporting the use of the quinolinic acid lesioned rat as an animal model of huntington's disease. |
1999-12-15 |
2023-08-12 |
rat |
| A Galindo, A Del Arco, F Mor. Endogenous GABA potentiates the potassium-induced release of dopamine in striatum of the freely moving rat: a microdialysis study. Brain research bulletin. vol 50. issue 3. 1999-12-02. PMID:10566983. |
endogenous gaba potentiates the potassium-induced release of dopamine in striatum of the freely moving rat: a microdialysis study. |
1999-12-02 |
2023-08-12 |
rat |
| A Galindo, A Del Arco, F Mor. Endogenous GABA potentiates the potassium-induced release of dopamine in striatum of the freely moving rat: a microdialysis study. Brain research bulletin. vol 50. issue 3. 1999-12-02. PMID:10566983. |
using microdialysis, a study was made of the effects of an increase of endogenous gaba on basal and potassium-stimulated release of dopamine in striatum of the awake rat. |
1999-12-02 |
2023-08-12 |
rat |
| A Galindo, A Del Arco, F Mor. Endogenous GABA potentiates the potassium-induced release of dopamine in striatum of the freely moving rat: a microdialysis study. Brain research bulletin. vol 50. issue 3. 1999-12-02. PMID:10566983. |
these results suggest that an increase of endogenous gaba is facilitating the stimulated release, but not the basal release, of dopamine in the striatum of the awake rat. |
1999-12-02 |
2023-08-12 |
rat |
| W Löscher, D Hönack, M Grame. Effect of depth electrode implantation with or without subsequent kindling on GABA turnover in various rat brain regions. Epilepsy research. vol 37. issue 2. 1999-11-19. PMID:10510976. |
compared to naive controls, prolonged electrode implantation in the amygdala induced a significant reduction of aoaa-induced gaba accumulation in amygdala, hippocampus, piriform cortex, olfactory bulb, frontal cortex, striatum, hypothalamus, tectum, and cerebellar cortex. |
1999-11-19 |
2023-08-12 |
rat |
| H M Haughey, J M Brown, A E Fleckenstein, G R Hanso. Oxygen radicals differentially affect Na+/Cl(-)-dependent transporters. European journal of pharmacology. vol 379. issue 1. 1999-11-15. PMID:10499378. |
to determine whether environmental differences between the striatum and hippocampus contributed to this lack of oxidative effect on norepinephrine transporters, synaptosomal gamma-aminobutyric acid (gaba) uptake was assessed in both regions. |
1999-11-15 |
2023-08-12 |
rat |
| H M Haughey, J M Brown, A E Fleckenstein, G R Hanso. Oxygen radicals differentially affect Na+/Cl(-)-dependent transporters. European journal of pharmacology. vol 379. issue 1. 1999-11-15. PMID:10499378. |
xanthine oxidase similarly decreased [3h]gaba uptake in both the striatum and hippocampus, supporting the conclusion that environmental differences did not account for the lack of effect on norepinephrine transport. |
1999-11-15 |
2023-08-12 |
rat |
| B J Jung, R Dawson, S A Sealey, J Peri. Endogenous GABA release is reduced in the striatum of cocaine-sensitized rats. Synapse (New York, N.Y.). vol 34. issue 2. 1999-11-09. PMID:10502309. |
endogenous gaba release is reduced in the striatum of cocaine-sensitized rats. |
1999-11-09 |
2023-08-12 |
rat |
| B J Jung, R Dawson, S A Sealey, J Peri. Endogenous GABA release is reduced in the striatum of cocaine-sensitized rats. Synapse (New York, N.Y.). vol 34. issue 2. 1999-11-09. PMID:10502309. |
these data are consistent with an overall decrease in gaba transmission, both pre- and postsynaptically, in the striatum of sensitized rats, which could contribute to enhanced striatal output and behavioral sensitization. |
1999-11-09 |
2023-08-12 |
rat |
| G Segovia, A Del Arco, F Mor. Effects of aging on the interaction between glutamate, dopamine, and GABA in striatum and nucleus accumbens of the awake rat. Journal of neurochemistry. vol 73. issue 5. 1999-11-05. PMID:10537066. |
effects of aging on the interaction between glutamate, dopamine, and gaba in striatum and nucleus accumbens of the awake rat. |
1999-11-05 |
2023-08-12 |
rat |
| G Segovia, A Del Arco, F Mor. Effects of aging on the interaction between glutamate, dopamine, and GABA in striatum and nucleus accumbens of the awake rat. Journal of neurochemistry. vol 73. issue 5. 1999-11-05. PMID:10537066. |
for that, the effects of an increase of the endogenous concentration of glutamate on the extracellular concentration of dopamine and gaba in striatum and nucleus accumbens of young (2-4 months), middle-aged (12-14 months), aged (27-33 months), and very aged (37 months) male wistar rats were studied. |
1999-11-05 |
2023-08-12 |
rat |
| G Segovia, A Del Arco, F Mor. Effects of aging on the interaction between glutamate, dopamine, and GABA in striatum and nucleus accumbens of the awake rat. Journal of neurochemistry. vol 73. issue 5. 1999-11-05. PMID:10537066. |
the findings of this study suggest that aging changes the interaction between endogenous glutamate, dopamine, and gaba in nucleus accumbens, but not in striatum, of the awake rat. |
1999-11-05 |
2023-08-12 |
rat |
| E M Jäverfalk-Hoyes, U Bondesson, D Westerlund, P E André. Simultaneous analysis of endogenous neurotransmitters and neuropeptides in brain tissue using capillary electrophoresis--microelectrospray-tandem mass spectrometry. Electrophoresis. vol 20. issue 7. 1999-10-20. PMID:10424476. |
in the striatum we could detect endogenous glutamate, gamma-aminobutyric acid (gaba), acetylcholine and dopamine, as well as the neuropeptides methionine-enkephalin and substance p 1-7 in the same analysis, using only 58 mm3 of brain tissue. |
1999-10-20 |
2023-08-12 |
monkey |
| P G Osborne, Y Hu, D N Covey, B N Barnes, Z Katz, K L Dre. Determination of striatal extracellular gamma-aminobutyric acid in non-hibernating and hibernating arctic ground squirrels using quantitative microdialysis. Brain research. vol 839. issue 1. 1999-10-20. PMID:10482793. |
this study determined extracellular concentrations of gamma-aminobutyric acid ([gaba](ecf)) in striatum of non-hibernating and hibernating arctic ground squirrels to test the hypothesis that an increase in [gaba](ecf) was associated with profound cns depression during hibernation. |
1999-10-20 |
2023-08-12 |
Not clear |
| E A Jones, J Q Wang, D C Mayer, J F McGint. The role of dorsal striatal GABA(A) receptors in dopamine agonist-induced behavior and neuropeptide gene expression. Brain research. vol 836. issue 1-2. 1999-10-15. PMID:10415409. |
the gaba(a) receptor antagonist, bicuculline, was unilaterally or bilaterally microinjected into the dorsal striatum of rats in a series of 3 studies. |
1999-10-15 |
2023-08-12 |
rat |
| E A Jones, J Q Wang, D C Mayer, J F McGint. The role of dorsal striatal GABA(A) receptors in dopamine agonist-induced behavior and neuropeptide gene expression. Brain research. vol 836. issue 1-2. 1999-10-15. PMID:10415409. |
these data suggest that blockade of gaba(a) receptors in the dorsal striatum does not affect dopamine agonist-stimulated behaviors or neuropeptide mrna expression in striatonigral neurons in the rat striatum. |
1999-10-15 |
2023-08-12 |
rat |
| J Abarca, G Busto. Differential regulation of glutamate, aspartate and gamma-amino-butyrate release by N-methyl-D-aspartate receptors in rat striatum after partial and extensive lesions to the nigro-striatal dopamine pathway. Neurochemistry international. vol 35. issue 1. 1999-10-12. PMID:10403427. |
the in vivo microdialysis methodology was used to assess the effect of n-methyl-d-aspartate (nmda) receptor ligands on glutamate (glu), aspartate (asp) and gamma-aminobutyrate (gaba) extracellular levels in the striatum of anaesthetized rats, after damage to the dopamine (da) nigrostriatal pathway by injections of different doses of 6-hydroxydopamine (6-oh-da) seven days earlier. |
1999-10-12 |
2023-08-12 |
rat |
| F Calon, M Morissette, M Goulet, R Grondin, P J Blanchet, P J Bédard, T Di Paol. Chronic D1 and D2 dopaminomimetic treatment of MPTP-denervated monkeys: effects on basal ganglia GABA(A)/benzodiazepine receptor complex and GABA content. Neurochemistry international. vol 35. issue 1. 1999-10-12. PMID:10403433. |
gaba concentrations remained unchanged in the striatum, external segment of globus pallidus and gpi following mptp denervation. |
1999-10-12 |
2023-08-12 |
monkey |
| N C Reynolds, W Lin, C M Cameron, D L Roeri. Extracellular perfusion of rat brain nuclei using microdialysis: a method for studying differential neurotransmitter release in response to neurotoxins. Brain research. Brain research protocols. vol 4. issue 2. 1999-10-12. PMID:10446406. |
the example provided compares changes in extracellular gamma-aminobutyric acid (gaba) concentrations in the striatum in response to quinolinic acid (qa, 0.24 m) and 3-nitropropionic acid (3-npa, 0.25 m). |
1999-10-12 |
2023-08-12 |
rat |