| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E A Kiyatkin, G V Rebe. Modulation of striatal neuronal activity by glutamate and GABA: iontophoresis in awake, unrestrained rats. Brain research. vol 822. issue 1-2. 1999-04-21. PMID:10082887. |
to examine the effects of glutamate (glu) and gamma-aminobutyric acid (gaba) and their interactions in the striatum under behaviorally relevant conditions, single-unit recording was combined with microiontophoresis in awake, unrestrained rats. |
1999-04-21 |
2023-08-12 |
rat |
| Y Kustova, J H Ha, M G Espey, Y Sei, D Morse, A S Basil. The pattern of neurotransmitter alterations in LP-BM5 infected mice is consistent with glutamatergic hyperactivation. Brain research. vol 793. issue 1-2. 1999-03-29. PMID:9630562. |
significant decreases (60-70%) in acetylcholine concentrations were observed in the striatum, cerebral cortex and hippocampus by 12 weeks after virus inoculation, while striatal gaba concentrations decreased to 50-60% at 8-12 weeks after infection. |
1999-03-29 |
2023-08-12 |
mouse |
| Y Ikarashi, M Yuzurihara, A Takahashi, Hirohisa Ishimaru, T Shiobara, Y Maruyam. Modulation of acetylcholine release via GABAA and GABAB receptors in rat striatum. Brain research. vol 816. issue 1. 1999-03-25. PMID:9878759. |
in order to investigate whether changes in acetylcholine (ach) release induced by gaba receptors are due to a direct or indirect effect on cholinergic neurons in the striatum, gabaa and gabab receptor bindings were assayed in the striatum microinjected with ethylcholine mustard aziridinium ion (af64a), a cholinergic neurotoxin. |
1999-03-25 |
2023-08-12 |
rat |
| Y Ikarashi, M Yuzurihara, A Takahashi, Hirohisa Ishimaru, T Shiobara, Y Maruyam. Modulation of acetylcholine release via GABAA and GABAB receptors in rat striatum. Brain research. vol 816. issue 1. 1999-03-25. PMID:9878759. |
these results suggest that gabaa, but not gabab receptors, are located on cholinergic neurons in the striatum, and that gaba can directly modulate ach release through stimulation of gabaa receptors. |
1999-03-25 |
2023-08-12 |
rat |
| Y Ikarashi, M Yuzurihara, A Takahashi, Hirohisa Ishimaru, T Shiobara, Y Maruyam. Modulation of acetylcholine release via GABAA and GABAB receptors in rat striatum. Brain research. vol 816. issue 1. 1999-03-25. PMID:9878759. |
findings further suggest that gaba can also indirectly modulate ach release through stimulation of gabab receptors located on non-cholinergic neuronal elements in the striatum. |
1999-03-25 |
2023-08-12 |
rat |
| W T O'Conno. Functional neuroanatomy of the basal ganglia as studied by dual-probe microdialysis. Nuclear medicine and biology. vol 25. issue 8. 1999-03-23. PMID:9863560. |
dual probe microdialysis was employed in intact rat brain to investigate the effect of intrastriatal perfusion with selective dopamine d1 and d2 receptor agonists and with c-fos antisense oligonucleotide on (a) local gaba release in the striatum; (b) the internal segment of the globus pallidus and the substantia nigra pars reticulata, which is the output site of the strionigral gaba pathway; and (c) the external segment of the globus pallidus, which is the output site of the striopallidal gaba pathway. |
1999-03-23 |
2023-08-12 |
rat |
| T Hanania, K M Johnso. Regulation of neurotransmitter release by endogenous nitric oxide in striatal slices. European journal of pharmacology. vol 359. issue 2-3. 1999-01-21. PMID:9832380. |
these data suggest that glutamatergic transmission through striatal nmda receptors is partially mediated through activation of the no/guanylate cyclase pathway and that this mechanism may contribute to the tetrodotoxin sensitivity of nmda-induced release of gaba and acetylcholine in the striatum. |
1999-01-21 |
2023-08-12 |
Not clear |
| G B Acost. Administration of cholecystokinin sulphated octapeptide (CCK-8S) induces changes on rat amino acid tissue levels and on a behavioral test for anxiety. General pharmacology. vol 31. issue 4. 1999-01-20. PMID:9792229. |
in the hippocampus, the concentration of both glutamate (27%) and taurine (29%) were reduced, whereas the levels of gaba in the striatum (29%) were increased. |
1999-01-20 |
2023-08-12 |
rat |
| H Goda, H Ooboshi, H Nakane, S Ibayashi, S Sadoshima, M Fujishim. Modulation of ischemia-evoked release of excitatory and inhibitory amino acids by adenosine A1 receptor agonist. European journal of pharmacology. vol 357. issue 2-3. 1999-01-07. PMID:9797030. |
concentrations of extracellular amino acids (glutamate, aspartate, gamma-aminobutyric acid (gaba) and taurine) and regional blood flow in the striatum of spontaneously hypertensive rats (shrs) were monitored during cerebral ischemia elicited by bilateral carotid artery occlusion for 40 min and recirculation. |
1999-01-07 |
2023-08-12 |
rat |
| B Szabo, L Dörner, C Pfreundtner, W Nörenberg, K Stark. Inhibition of GABAergic inhibitory postsynaptic currents by cannabinoids in rat corpus striatum. Neuroscience. vol 85. issue 2. 1999-01-05. PMID:9622239. |
the results show that activation of cb1 cannabinoid receptors reduces gabaergic inhibitory postsynaptic currents in medium spiny neurons of the corpus striatum: the likely mechanism is presynaptic inhibition of gaba release from terminals of recurrent axons of the medium spiny neurons themselves. |
1999-01-05 |
2023-08-12 |
rat |
| J Z Little, T J Teyle. GABAa receptor-mediated field potentials are enhanced in area CA1 following prenatal cocaine exposure. Brain research. Developmental brain research. vol 110. issue 1. 1998-11-16. PMID:9733940. |
increases have been reported for cortical catecholamine and indoleamine receptor number and binding affinity, in the subunit expression of glutamatergic nmda and ampa receptors in the striatum, and in gaba immunoreactivity in the anterior cingulate cortex. |
1998-11-16 |
2023-08-12 |
rabbit |
| C Y Guezennec, A Abdelmalki, B Serrurier, D Merino, X Bigard, M Berthelot, C Pierard, M Pere. Effects of prolonged exercise on brain ammonia and amino acids. International journal of sports medicine. vol 19. issue 5. 1998-10-29. PMID:9721055. |
in this group, the gaba level decreased in striatum. |
1998-10-29 |
2023-08-12 |
rat |
| C Y Guezennec, A Abdelmalki, B Serrurier, D Merino, X Bigard, M Berthelot, C Pierard, M Pere. Effects of prolonged exercise on brain ammonia and amino acids. International journal of sports medicine. vol 19. issue 5. 1998-10-29. PMID:9721055. |
the reduced availability of this gaba precursor decreases gaba levels only in the striatum of tr group by 45% of the resting value. |
1998-10-29 |
2023-08-12 |
rat |
| J Peris, B J Jung, A Resnick, P Walker, O Malakhova, Y Bokrand, D Wielb. Antisense inhibition of striatal GABAA receptor proteins decreases GABA-stimulated chloride uptake and increases cocaine sensitivity in rats. Brain research. Molecular brain research. vol 57. issue 2. 1998-10-20. PMID:9675429. |
injection of fluorescein-conjugated asodns indicated that asodn is present in striatum at times during which behavioral and neurochemical indices of gaba receptor function are decreased. |
1998-10-20 |
2023-08-12 |
rat |
| A Del Arco, T R Castañeda, F Mor. Amphetamine releases GABA in striatum of the freely moving rat: involvement of calcium and high affinity transporter mechanisms. Neuropharmacology. vol 37. issue 2. 1998-10-01. PMID:9680244. |
amphetamine releases gaba in striatum of the freely moving rat: involvement of calcium and high affinity transporter mechanisms. |
1998-10-01 |
2023-08-12 |
rat |
| A Del Arco, T R Castañeda, F Mor. Amphetamine releases GABA in striatum of the freely moving rat: involvement of calcium and high affinity transporter mechanisms. Neuropharmacology. vol 37. issue 2. 1998-10-01. PMID:9680244. |
using microdialysis the effect was investigated of amphetamine (amph) infusions into the striatum on the release of gaba in the freely moving rat. |
1998-10-01 |
2023-08-12 |
rat |
| H J Waldvogel, J M Fritschy, H Mohler, R L Faul. GABA(A) receptors in the primate basal ganglia: an autoradiographic and a light and electron microscopic immunohistochemical study of the alpha1 and beta2,3 subunits in the baboon brain. The Journal of comparative neurology. vol 397. issue 3. 1998-09-24. PMID:9674559. |
these results show that the subunit composition of gaba(a) receptors varies between the striosome and the matrix compartments in the striatum and that there is receptor subunit homogeneity in the globus pallidus. |
1998-09-24 |
2023-08-12 |
Not clear |
| G F Woote. Functional anatomical and behavioral consequences of dopamine receptor stimulation. Annals of the New York Academy of Sciences. vol 835. 1998-06-18. PMID:9616770. |
supportive evidence includes the ability of d1 agonists to facilitate gaba release in the striatum and to increase the firing rates of striatonigral neurons. |
1998-06-18 |
2023-08-12 |
Not clear |
| E Sanna, C Motzo, M Usala, D Pau, E Cagetti, G Biggi. Functional changes in rat nigral GABA(A) receptors induced by degeneration of the striatonigral GABAergic pathway: an electrophysiological study of receptors incorporated into Xenopus oocytes. Journal of neurochemistry. vol 70. issue 6. 1998-06-05. PMID:9603220. |
this approach has now been applied to evaluate changes in the function of nigral gaba(a) receptors after degeneration of the striatonigral gabaergic pathway induced by the unilateral infusion of kainic acid into the rat striatum. |
1998-06-05 |
2023-08-12 |
rat |
| Y Odagaki, N Nishi, T Koyam. Receptor-mediated and receptor-independent activation of G-proteins in rat brain membranes. Life sciences. vol 62. issue 17-18. 1998-05-26. PMID:9585132. |
receptor-mediated high-affinity gtpase activity was detectable preferentially for the gi subfamily associated with adenylyl cyclase inhibition mediated by group ii metabotropic glutamate, pirenzepine-insensitive muscarinic acetylcholine, gaba(b), adenosine a1, dopamine d2-like (striatum), and serotonin 5-ht1a (hippocampus) receptors. |
1998-05-26 |
2023-08-12 |
rat |