| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Viola, M Marder, J Nuñez, L Izquierdo, C Wasowski, C Wolfman, P Ardenghi, D Barros, J H Medina, A C Paladin. 6-Methyl-3'-bromoflavone, a high-affinity ligand for the benzodiazepine binding site of the GABA(A) receptor with some antagonistic properties. Biochemical and biophysical research communications. vol 262. issue 3. 1999-10-07. PMID:10471378. |
the gaba ratio of 1.03 for [(3)h]flunitrazepam binding to cerebral cortex, 0.76 for cerebellum, 0.7 for hippocampus, 0.7 for striatum, and 0.8 for spinal cord indicated an antagonistic or weak inverse agonistic profile of 6-methyl-3'-bromoflavone on bdz-bs. |
1999-10-07 |
2023-08-12 |
Not clear |
| L Sussel, O Marin, S Kimura, J L Rubenstei. Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development (Cambridge, England). vol 126. issue 15. 1999-09-21. PMID:10393115. |
a mouse deficient in nkx2.1 function does not form pallidal structures, lacks basal forebrain trka-positive neurons (probable cholinergic neurons) and has reduced numbers of cortical cells expressing gaba, dlx2 and calbindin that migrate from the pallidum through the striatum and into the cortex. |
1999-09-21 |
2023-08-12 |
mouse |
| T P Bonnert, R M McKernan, S Farrar, B le Bourdellès, R P Heavens, D W Smith, L Hewson, M R Rigby, D J Sirinathsinghji, N Brown, K A Wafford, P J Whitin. theta, a novel gamma-aminobutyric acid type A receptor subunit. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 17. 1999-09-09. PMID:10449790. |
within the rat striatum, this subunit coassembles with alpha2, beta1, and gamma1, suggesting that gamma-aminobutyric acid type a receptors consisting of arrangements other than alpha beta + gamma, delta, or epsilon do exist. |
1999-09-09 |
2023-08-12 |
human |
| I Expósito, A Del Arco, G Segovia, F Mor. Endogenous dopamine increases extracellular concentrations of glutamate and GABA in striatum of the freely moving rat: involvement of D1 and D2 dopamine receptors. Neurochemical research. vol 24. issue 7. 1999-09-08. PMID:10403624. |
endogenous dopamine increases extracellular concentrations of glutamate and gaba in striatum of the freely moving rat: involvement of d1 and d2 dopamine receptors. |
1999-09-08 |
2023-08-12 |
rat |
| I Expósito, A Del Arco, G Segovia, F Mor. Endogenous dopamine increases extracellular concentrations of glutamate and GABA in striatum of the freely moving rat: involvement of D1 and D2 dopamine receptors. Neurochemical research. vol 24. issue 7. 1999-09-08. PMID:10403624. |
interactions between endogenous dopamine, glutamate, gaba, and taurine were investigated in striatum of the freely moving rat by using microdialysis. |
1999-09-08 |
2023-08-12 |
rat |
| I Expósito, A Del Arco, G Segovia, F Mor. Endogenous dopamine increases extracellular concentrations of glutamate and GABA in striatum of the freely moving rat: involvement of D1 and D2 dopamine receptors. Neurochemical research. vol 24. issue 7. 1999-09-08. PMID:10403624. |
these data suggest that endogenous dopamine, through both d1 and d2 dopamine receptors, plays a role in releasing glutamate and gaba in striatum of the freely moving rat. |
1999-09-08 |
2023-08-12 |
rat |
| R D Mayfield, B A Jones, H A Miller, J K Simosky, G A Larson, N R Zahnise. Modulation of endogenous GABA release by an antagonistic adenosine A1/dopamineD1 receptor interaction in rat brain limbic regions but not basal ganglia. Synapse (New York, N.Y.). vol 33. issue 4. 1999-08-30. PMID:10421708. |
we examined the functional significance of a(1) and d(1) receptor subtypes in modulating electrically evoked endogenous gaba release from slices/punches of rat basal ganglia (striatum, globus pallidus, striatum containing globus pallidus, and substantia nigra reticulata) and limbic regions (ventral pallidum and nucleus accumbens). |
1999-08-30 |
2023-08-12 |
rat |
| E S Vizi, B Sperlág. Separation of carrier mediated and vesicular release of GABA from rat brain slices. Neurochemistry international. vol 34. issue 5. 1999-08-19. PMID:10397369. |
however, the fraction of [3h]gaba outflow evoked by ouabain was much higher in the hippocampus than in the striatum. |
1999-08-19 |
2023-08-12 |
rat |
| H Steiner, C R Gerfe. Enkephalin regulates acute D2 dopamine receptor antagonist-induced immediate-early gene expression in striatal neurons. Neuroscience. vol 88. issue 3. 1999-08-02. PMID:10363818. |
projection neurons of the striatum release opioid peptides in addition to gaba. |
1999-08-02 |
2023-08-12 |
Not clear |
| Y Yamamoto, T Kakigi, K Maed. Intra-striatal phencyclidine inhibits N-methyl-D-aspartic acid-stimulated increase in glutamate levels of freely moving rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 23. issue 1. 1999-08-02. PMID:10368862. |
the authors investigated the effect of local phencyclidine (phenylcyclohexylpiperidine, pcp) on extracellular levels of glutamate and gamma-amino butyric acid (gaba) in rat striatum using in vivo microdialysis. |
1999-08-02 |
2023-08-12 |
rat |
| M Eltz. Multiple mechanisms of action: the pharmacological profile of budipine. Journal of neural transmission. Supplementum. vol 56. 1999-08-02. PMID:10370904. |
by means of these multiple mechanisms, budipine might correct the imbalance of striatal output pathways by restoring da levels in the striatum, and positively influence the secondary changes in other transmitter systems (glutamate, acetylcholine, gaba) observed in parkinson's disease. |
1999-08-02 |
2023-08-12 |
human |
| C A Paladini, P Celada, J M Teppe. Striatal, pallidal, and pars reticulata evoked inhibition of nigrostriatal dopaminergic neurons is mediated by GABA(A) receptors in vivo. Neuroscience. vol 89. issue 3. 1999-07-07. PMID:10199614. |
the effects of local pressure application of the selective gaba(a) antagonists, bicuculline and picrotoxin, and the gaba(b) antagonists, saclofen and cgp-55845a, on the inhibition of dopaminergic neurons elicited by single-pulse electrical stimulation of striatum, globus pallidus, and the thalamic axon terminals of the substantia nigra pars reticulata projection neurons were recorded in vivo. |
1999-07-07 |
2023-08-12 |
rat |
| P Celada, C A Paladini, J M Teppe. GABAergic control of rat substantia nigra dopaminergic neurons: role of globus pallidus and substantia nigra pars reticulata. Neuroscience. vol 89. issue 3. 1999-07-07. PMID:10199615. |
the three principal gabaergic inputs to nigral dopaminergic neurons arise from striatum, globus pallidus and from the axon collaterals of nigral pars reticulata projection neurons, each of which appear to act in vivo primarily on gaba(a) receptors (see preceding paper). |
1999-07-07 |
2023-08-12 |
rat |
| J L Bizon, J C Lauterborn, C M Gal. Subpopulations of striatal interneurons can be distinguished on the basis of neurotrophic factor expression. The Journal of comparative neurology. vol 408. issue 2. 1999-06-28. PMID:10333275. |
in situ hybridization was used to identify the distribution and the neurotransmitter phenotypes (i.e., cholinergic and gamma-aminobutyric acid [gaba]-ergic) of cells expressing acidic fibroblast growth factor (afgf), glial cell line-derived neurotrophic factor (gdnf), or nerve growth factor (ngf) mrna in adult rat striatum. |
1999-06-28 |
2023-08-12 |
rat |
| C Kohlhauser, S Kaehler, W Mosgoeller, N Singewald, D Kouvelas, H Prast, H Hoeger, B Lube. Histological changes and neurotransmitter levels three months following perinatal asphyxia in the rat. Life sciences. vol 64. issue 23. 1999-06-25. PMID:10372653. |
morphometry on nissl - stained sections was used to determine neuronal death in frontal cortex, striatum, hippocampus ca1, hypothalamus and cerebellum l1, and the amino acids glutamate, glutamine, aspartate, gaba, taurine, arginine as well as histamine, serotonin and 5-hydroxy-indoleacetic acid were determined in several brain regions and areas. |
1999-06-25 |
2023-08-12 |
rat |
| K Sasaki, S Hatta, M Haga, H Ohshik. Effects of bilobalide on gamma-aminobutyric acid levels and glutamic acid decarboxylase in mouse brain. European journal of pharmacology. vol 367. issue 2-3. 1999-06-22. PMID:10078989. |
this study examined the effects of bilobalide on the level of gaba and glutamate, the activity and the amount of glutamic acid decarboxylase (ec 4.1.1.15), and the function of gaba(a) receptors in the hippocampus, cerebral cortex and striatum of the mouse. |
1999-06-22 |
2023-08-12 |
mouse |
| L Jóźwiak, M Sieklucka-Dziuba, Z Kleinro. Behavioral studies of the effects of moderate oligemic hypoxia caused by bilateral clamping of carotid arteries in mice. Impairment of spatial working memory. Polish journal of pharmacology. vol 50. issue 4-5. 1999-06-22. PMID:10091712. |
the experiments carried out on albino swiss mice indicated that bilateral clamping of carotid arteries (bcca) for 30 min caused no neuronal damage but produced an increase in gaba content in the hippocampus, striatum and frontal cortex. |
1999-06-22 |
2023-08-12 |
mouse |
| K B Burrows, C K Meshu. High-dose methamphetamine treatment alters presynaptic GABA and glutamate immunoreactivity. Neuroscience. vol 90. issue 3. 1999-06-14. PMID:10218784. |
altered presynaptic gaba immunolabeling and terminal size were found in both the striatum and globus pallidus, suggesting that dynamic changes occur in the striatopallidal pathway following methamphetamine-induced dopamine loss. |
1999-06-14 |
2023-08-12 |
rat |
| C K Meshul, N Emre, C M Nakamura, C Allen, M K Donohue, J F Buckma. Time-dependent changes in striatal glutamate synapses following a 6-hydroxydopamine lesion. Neuroscience. vol 88. issue 1. 1999-04-26. PMID:10051185. |
these data suggest that there are compensatory changes in glutamatergic synapses within the striatum following a 6-hydroxydopamine lesion that appear to be independent of the level of striatal dopamine or gaba. |
1999-04-26 |
2023-08-12 |
rat |
| S Guirado, J C Dávila, M A Real, L Medin. Nucleus accumbens in the lizard Psammodromus algirus: chemoarchitecture and cortical afferent connections. The Journal of comparative neurology. vol 405. issue 1. 1999-04-22. PMID:10022193. |
the nucleus accumbens contains two chemoarchitectonically different fields: a rostromedial field that stains heavily for substance p, dopamine, gaba(a) receptor, and a caudolateral field that stains only lightly to moderately for them, appearing more similar to the adjacent striatum. |
1999-04-22 |
2023-08-12 |
Not clear |