| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Godefroy, J Weil-Fugazza, D Coudert, J M Besso. Effect of acute administration of morphine on newly synthesized 5-hydroxytryptamine in spinal cord of the rat. Brain research. vol 199. issue 2. 1980-12-16. PMID:6158357. |
(1) in the spinal cord morphine induced an increase in [3h]trp uptake which was significant 30 and 60 min after the injection, and a clear enhancement of the formation of [3h]5-ht which was significant 15 min after the injection and which peaked at 30 min. |
1980-12-16 |
2023-08-12 |
rat |
| P C Jobe, T B Ra. The effects of reserpine, iproniazid and L-dopa on electrically-induced spinal cord seizures. Research communications in chemical pathology and pharmacology. vol 29. issue 3. 1980-12-16. PMID:7423021. |
the effects of selected drug treatments on spinal cord norepinephrine (ne), dopamine (da), and 5-hydroxytryptamine (5-ht) were compared to the effects of these same treatments on electrically-induced spinal cord seizure. |
1980-12-16 |
2023-08-12 |
Not clear |
| P J Soja, J G Sinclai. Evidence against a serotonin involvement in the tonic descending inhibition of nociceptor-driven neurons in the cat spinal cord. Brain research. vol 199. issue 1. 1980-11-25. PMID:7407625. |
evidence against a serotonin involvement in the tonic descending inhibition of nociceptor-driven neurons in the cat spinal cord. |
1980-11-25 |
2023-08-12 |
cat |
| S Bourgoin, J L Oliveras, J Bruxelle, M Hamon, J M Besso. Electrical stimulation of the nucleus raphe magnus in the rat. Effects on 5-HT metabolism in the spinal cord. Brain research. vol 194. issue 2. 1980-09-28. PMID:6155975. |
effects on 5-ht metabolism in the spinal cord. |
1980-09-28 |
2023-08-12 |
rat |
| S Bourgoin, J L Oliveras, J Bruxelle, M Hamon, J M Besso. Electrical stimulation of the nucleus raphe magnus in the rat. Effects on 5-HT metabolism in the spinal cord. Brain research. vol 194. issue 2. 1980-09-28. PMID:6155975. |
the direct electrical stimulation (with biphasic pulses of 1 msec, 10 pulses/sec, 200 microa, for 30 min) of the nucleus raphe magnus in chloral hydrate anaesthesized rats produced a significant acceleration (+50%) of 5-ht synthesis in the spinal cord as revealed by the increased rate of 5-htp accumulation occurring at this level after the blockade of central 5-htp decarboxylase with benserazid. |
1980-09-28 |
2023-08-12 |
rat |
| S Bourgoin, J L Oliveras, J Bruxelle, M Hamon, J M Besso. Electrical stimulation of the nucleus raphe magnus in the rat. Effects on 5-HT metabolism in the spinal cord. Brain research. vol 194. issue 2. 1980-09-28. PMID:6155975. |
the acceleration of 5-ht synthesis was likely not due to an increased availability of tryptophan for the rate-limiting enzyme, tryptophan hydroxylase, since the concentration of this amino acid was changed neither in the spinal cord, nor in the forebrain of stimulated rats. |
1980-09-28 |
2023-08-12 |
rat |
| S Bourgoin, J L Oliveras, J Bruxelle, M Hamon, J M Besso. Electrical stimulation of the nucleus raphe magnus in the rat. Effects on 5-HT metabolism in the spinal cord. Brain research. vol 194. issue 2. 1980-09-28. PMID:6155975. |
the measurement of tryptophan hydroxylase activity in soluble extracts from the spinal cord of control and stimulated rats revealed that the acceleration in 5-ht synthesis produced by the electrical stimulation of the nucleus raphe magnus was not associated with a persisting activation of this enzyme. |
1980-09-28 |
2023-08-12 |
rat |
| S Bourgoin, J L Oliveras, J Bruxelle, M Hamon, J M Besso. Electrical stimulation of the nucleus raphe magnus in the rat. Effects on 5-HT metabolism in the spinal cord. Brain research. vol 194. issue 2. 1980-09-28. PMID:6155975. |
although one cannot completely exclude that a short-lasting activation of tryptophan hydroxylase, no longer detectable in soluble extracts, has occurred in the spinal cord of stimulated rats, the present findings rather suggest that the rate of 5-ht synthesis can be controlled by factors other than only the concentration of tryptophan and the intrinsic activity of tryptophan hydroxylase in serotoninergic neurons. |
1980-09-28 |
2023-08-12 |
rat |
| M Davis, D I Strachan, E Kas. Excitatory and inhibitory effects of serotonin on sensorimotor reactivity measured with acoustic startle. Science (New York, N.Y.). vol 209. issue 4455. 1980-09-26. PMID:7394520. |
when infused onto the spinal cord, serotonin produced a dose-dependent increase in startle. |
1980-09-26 |
2023-08-12 |
rat |
| S O Ogren, A C Hol. Test-specific effects of the 5-HT reuptake inhibitors alaproclate and zimelidine on pain sensitivity and morphine analgesia. Journal of neural transmission. vol 47. issue 4. 1980-09-23. PMID:6446594. |
the effects of alaproclate and zimelidine on 5-ht uptake mechanisms in the hypothalamus and spinal cord were also studied. |
1980-09-23 |
2023-08-12 |
rat |
| S O Ogren, A C Hol. Test-specific effects of the 5-HT reuptake inhibitors alaproclate and zimelidine on pain sensitivity and morphine analgesia. Journal of neural transmission. vol 47. issue 4. 1980-09-23. PMID:6446594. |
zimelidine inhibited 5-ht uptake with equal potency in the hypothalamus and spinal cord, while alaproclate produced a greater inhibition of 5-ht uptake in the hypothalamus. |
1980-09-23 |
2023-08-12 |
rat |
| S O Ogren, A C Hol. Test-specific effects of the 5-HT reuptake inhibitors alaproclate and zimelidine on pain sensitivity and morphine analgesia. Journal of neural transmission. vol 47. issue 4. 1980-09-23. PMID:6446594. |
it is suggested that various aspects of pain sensitivity and morphine analgesia may involve different 5-ht pathways in the brain and spinal cord. |
1980-09-23 |
2023-08-12 |
rat |
| Y Shigetom. Biogenic amine study in the spinal cord of experimental cervical myelopathy. Nihon Seikeigeka Gakkai zasshi. vol 54. issue 4. 1980-09-23. PMID:7391630. |
concentrations of norepinephrine (ne), dopamine (da), and serotonin (5ht) within cervical spinal cord specimens were determined using rabbits as the experimental animals. |
1980-09-23 |
2023-08-12 |
Not clear |
| R A Brodner, G J Dohrmann, R H Roth, R A Rubi. Correlation of cerebrospinal fluid serotonin and altered spinal cord blood flow in experimental trauma. Surgical neurology. vol 13. issue 5. 1980-08-25. PMID:7384998. |
correlation of cerebrospinal fluid serotonin and altered spinal cord blood flow in experimental trauma. |
1980-08-25 |
2023-08-12 |
Not clear |
| R A Brodner, G J Dohrmann, R H Roth, R A Rubi. Correlation of cerebrospinal fluid serotonin and altered spinal cord blood flow in experimental trauma. Surgical neurology. vol 13. issue 5. 1980-08-25. PMID:7384998. |
serotonin levels in the cerebrospinal fluid (csf) were determined at various time intervals following experimental spinal cord trauma and correlated with alterations in the intramedullary blood flow. |
1980-08-25 |
2023-08-12 |
Not clear |
| R A Brodner, G J Dohrmann, R H Roth, R A Rubi. Correlation of cerebrospinal fluid serotonin and altered spinal cord blood flow in experimental trauma. Surgical neurology. vol 13. issue 5. 1980-08-25. PMID:7384998. |
the correlation between elevated csf serotonin and decreased blood flow in the traumatized spinal cord suggests that serotonin may have pathogenetic importance relative to posttraumatic alterations in the intramedullary microcirculation. |
1980-08-25 |
2023-08-12 |
Not clear |
| R A Brodner, G J Dohrmann, R H Roth, R A Rubi. Correlation of cerebrospinal fluid serotonin and altered spinal cord blood flow in experimental trauma. Surgical neurology. vol 13. issue 5. 1980-08-25. PMID:7384998. |
the possible role of serotonin in the pathophysiology of blood flow changes following experimental spinal cord injury are discussed as are the therapeutic implications. |
1980-08-25 |
2023-08-12 |
Not clear |
| T L Yaksh, G M Tyc. Resting and K+-evoked release of serotonin and norephinephrine in vivo from the rat and cat spinal cord. Brain research. vol 192. issue 1. 1980-08-15. PMID:7378777. |
resting and k+-evoked release of serotonin and norephinephrine in vivo from the rat and cat spinal cord. |
1980-08-15 |
2023-08-12 |
rat |
| T L Yaksh, G M Tyc. Resting and K+-evoked release of serotonin and norephinephrine in vivo from the rat and cat spinal cord. Brain research. vol 192. issue 1. 1980-08-15. PMID:7378777. |
using a spinal superfusion system, the release of serotonin (5-ht) and norepinephrine (ne) from rat and cat spinal cord was measured using a high performance liquid chromatograph with an electrochemical detector. |
1980-08-15 |
2023-08-12 |
rat |
| V Crunelli, S Bernasconi, R Samani. Evidence against serotonin involvement in the tonic component of electrically induced convulsions and in carbamazepine anticonvulsant activity. Psychopharmacology. vol 66. issue 1. 1980-06-16. PMID:120546. |
the results, in relation to the high selectivity of the experimental procedures employed to deplete brain and spinal cord serotonin, do not bear out any involvement of serotonin in the tonic component of electrically induced convulsions or in the action of carbamazepine. |
1980-06-16 |
2023-08-11 |
rat |