| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Jonsson, H Hallman, F Ponzio, S Ros. DSP4 (N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine)--a useful denervation tool for central and peripheral noradrenaline neurons. European journal of pharmacology. vol 72. issue 2-3. 1981-09-25. PMID:6265244. |
in the mouse cns, however, there was a marked and long-lasting na reduction, especially in the cerebral and cerebellar cortex and spinal cord, leaving dopamine (da) and serotonin (5-ht) neurons apparently unaffected. |
1981-09-25 |
2023-08-12 |
mouse |
| J Weil-Fugazza, F Godefroy, D Coudert, J M Besso. Morphine analgesia and newly synthesized 5-hydroxytryptamine in the dorsal and the ventral halves of the spinal cord of the rat. Brain research. vol 214. issue 2. 1981-08-27. PMID:6263422. |
morphine analgesia and newly synthesized 5-hydroxytryptamine in the dorsal and the ventral halves of the spinal cord of the rat. |
1981-08-27 |
2023-08-12 |
rat |
| J Weil-Fugazza, F Godefroy, D Coudert, J M Besso. Morphine analgesia and newly synthesized 5-hydroxytryptamine in the dorsal and the ventral halves of the spinal cord of the rat. Brain research. vol 214. issue 2. 1981-08-27. PMID:6263422. |
in the rat, morphine (5 mg/kg, s.c.) induced an increase in 5-hydroxytryptamine (5-ht) synthesis in the spinal cord. |
1981-08-27 |
2023-08-12 |
rat |
| R Ings, B Pappa. Neonatal intraspinal 6-hydroxydopamine: depletion of norepinephrine but not dopamine. European journal of pharmacology. vol 70. issue 4. 1981-08-20. PMID:6263641. |
neither 6-ohda alone nor in combination with desmethylimipramine pretreatment depleted spinal cord dopamine of serotonin. |
1981-08-20 |
2023-08-12 |
rat |
| C A Marsde. Effect of L-tryptophan on mouse brain 5-hydroxytryptamine: comparison of values obtained using a fluorimetric assay and a liquid Chromatographic assay with electrochemical detection. Journal of neurochemistry. vol 36. issue 5. 1981-08-20. PMID:7241125. |
5-hydroxytryptamine (5-ht) in mouse brain and spinal cord was assayed in the same samples using a fluorimetric assay and a high pressure liquid chromatographic (hplc) assay with electrochemical detection. |
1981-08-20 |
2023-08-12 |
mouse |
| S O Ogren, S B Ross, H Hall, A C Holm, A L Reny. The pharmacology of zimelidine: a 5-HT selective reuptake inhibitor. Acta psychiatrica Scandinavica. Supplementum. vol 290. 1981-06-13. PMID:6452789. |
zim in vivo blocked the 5-ht uptake mechanism in the cerebral cortex, hippocampus, striatum, hypothalamus and spinal cord, thus indicating effects on both the ascending and descending 5-ht pathways. |
1981-06-13 |
2023-08-12 |
mouse |
| A A Larson, C Chinn, H K Proudfit, E G Anderso. Dual actions of lysergic acid diethylamide tartrate (LSD), 2-bromo-D-lysergic acid diethylamide bitartrate (BOL) and methysergide on dorsal root potentials evoked by stimulation of raphe nuclei. The Journal of pharmacology and experimental therapeutics. vol 217. issue 1. 1981-05-26. PMID:6110778. |
a variety of drugs reported to antagonize serotonin were found to affect spinal cord potentials evoked by electrical stimulation of the caudal raphe nuclei of the cat. |
1981-05-26 |
2023-08-12 |
cat |
| Jeanne Weil-Fugazza, Françoise Godefroy, Danielle Coudert, Jean-Marie Besso. Total and free serum tryptophan levels and brain 5-hydroxytryptamine metabolism in arthritic rats. Pain. vol 9. issue 3. 1981-05-26. PMID:6163124. |
tryptophan, 5-hydroxytryptamine and 5-hydroxyindoleacetic acid levels are increased in the brain and the spinal cord at 15 days. |
1981-05-26 |
2023-08-12 |
human |
| B Ault, R H Evans, A A Francis, D J Oakes, J C Watkin. Selective depression of excitatory amino acid induced depolarizations by magnesium ions in isolated spinal cord preparations. The Journal of physiology. vol 307. 1981-05-21. PMID:6259339. |
mg2+ did not depress motoneurone depolarization produced by 5-ht in the rat spinal cord or the depolarizing action of gaba on primary afferent terminals of the isolated frog spinal cord. |
1981-05-21 |
2023-08-12 |
rat |
| B A Pappas, G R Breese, R B Mailman, R A Muelle. Importance of the Locus coeruleus and involvement of alpha-adrenergic receptors in the post-decapitation reflex in the rat. Psychopharmacology. vol 69. issue 2. 1981-03-17. PMID:6256789. |
reduction of brain and spinal cord norepinephrine (ne) caused by neonatal administration of 6-hydroxydopamine (6-ohda) or 5,7-dihydroxytryptamine, which also reduced brain serotonin, decreased all components of the pdr. |
1981-03-17 |
2023-08-12 |
rat |
| B G Hinwood, J D Yeo, A D Kidma. Monoamine and tissue fluid levels in contused spinal cord of sheep. Journal of neurochemistry. vol 35. issue 4. 1981-03-17. PMID:7452290. |
methods are described for the determination of sheep spinal cord tissue fluid content and norepinephrine, serotonin, and dopamine concentrations after experimental injury. |
1981-03-17 |
2023-08-12 |
Not clear |
| H K Proudfi. Effects of raphe magnus and raphe pallidus lesions on morphine-induced analgesia and spinal cord monoamines. Pharmacology, biochemistry, and behavior. vol 13. issue 5. 1981-02-19. PMID:7443740. |
in addition, lesion-induced changes in spinal cord serotonin content and morphine analgesia were significantly correlated which lends support to the conclusion that the bulbospinal serotonin systems are necessary for the mediation of morphine effects. |
1981-02-19 |
2023-08-12 |
Not clear |
| P C Jobe, T W Woods, T B Ra. Effects of fluoxetine on electrically-induced spinal cord seizures in rats. Research communications in chemical pathology and pharmacology. vol 30. issue 1. 1981-01-26. PMID:6159671. |
the effects of fluoxetine [an inhibitor of 5-hydroxytryptamine (5-ht) reuptake] on electrically-induced spinal cord seizures were determined by monitoring alterations in the total duration of seizure, as well as the durations of tonic flexion and extension. |
1981-01-26 |
2023-08-12 |
rat |
| P C Jobe, T W Woods, T B Ra. Effects of fluoxetine on electrically-induced spinal cord seizures in rats. Research communications in chemical pathology and pharmacology. vol 30. issue 1. 1981-01-26. PMID:6159671. |
the capacity of fluoxetine to inhibit 5-ht reuptake in the spinal cord was confirmed by measurements of 5-hydroxyindoleacetic acid (5-hiaa) content. |
1981-01-26 |
2023-08-12 |
rat |
| P C Jobe, T W Woods, T B Ra. Effects of fluoxetine on electrically-induced spinal cord seizures in rats. Research communications in chemical pathology and pharmacology. vol 30. issue 1. 1981-01-26. PMID:6159671. |
these results further support our earlier suggestion that 5-ht containing neurons in the spinal cord do not modulate electrically-induced seizures. |
1981-01-26 |
2023-08-12 |
rat |
| M Davis, D I Astrachan, P M Gendelman, D S Gendelma. 5-Methoxy-N,N-dimethyltryptamine: spinal cord and brainstem mediation of excitatory effects on acoustic startle. Psychopharmacology. vol 70. issue 2. 1981-01-26. PMID:6776570. |
the results were discussed in terms of a new theory, which suggests that stimulation of serotonin receptors in the spinal cord enhance startle whereas serotonin receptors in the forebrain inhibit startle. |
1981-01-26 |
2023-08-12 |
rat |
| P C Jobe, T B Ra. Effects of norepinephrine and 5-hydroxytryptamine reuptake inhibitors on electrically-induced spinal cord seizures in rats. Research communications in chemical pathology and pharmacology. vol 30. issue 1. 1981-01-26. PMID:6968962. |
effects of norepinephrine and 5-hydroxytryptamine reuptake inhibitors on electrically-induced spinal cord seizures in rats. |
1981-01-26 |
2023-08-12 |
rat |
| C P VanderMaelen, G K Aghajania. Intracellular studies showing modulation of facial motoneurone excitability by serotonin. Nature. vol 287. issue 5780. 1980-12-18. PMID:7421993. |
moreover, studies using extracellular single-cell recording techniques indicate that serotonin in small amounts facilitates synaptically or glutamate-induced excitation of mammalian motoneurones in the facial nucleus and spinal cord. |
1980-12-18 |
2023-08-12 |
rat |
| F Godefroy, J Weil-Fugazza, D Coudert, J M Besso. Effect of acute administration of morphine on newly synthesized 5-hydroxytryptamine in spinal cord of the rat. Brain research. vol 199. issue 2. 1980-12-16. PMID:6158357. |
effect of acute administration of morphine on newly synthesized 5-hydroxytryptamine in spinal cord of the rat. |
1980-12-16 |
2023-08-12 |
rat |
| F Godefroy, J Weil-Fugazza, D Coudert, J M Besso. Effect of acute administration of morphine on newly synthesized 5-hydroxytryptamine in spinal cord of the rat. Brain research. vol 199. issue 2. 1980-12-16. PMID:6158357. |
the effect of morphine (10 mg/kg, s.c.) on the rate of [3h]5-ht synthesis in brain and spinal cord following intravenous injection of [2h]tryptophan was studied in the rat. |
1980-12-16 |
2023-08-12 |
rat |