| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jakub Jedynak, Matthew Hearing, Anna Ingebretson, Stephanie R Ebner, Matthew Kelly, Rachel A Fischer, Saïd Kourrich, Mark J Thoma. Cocaine and Amphetamine Induce Overlapping but Distinct Patterns of AMPAR Plasticity in Nucleus Accumbens Medium Spiny Neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 2. 2016-09-20. PMID:26068728. |
in rodent addiction models, persistent changes in excitatory glutamatergic neurotransmission in the nucleus accumbens (nac) appear to drive this drug-induced behavioral plasticity. |
2016-09-20 |
2023-08-13 |
mouse |
| Ramya Varatharajan, Kevin Joseph, Sonya Carvalho Neto, Ulrich G Hofmann, Andreas Moser, Volker Tronnie. Electrical high frequency stimulation modulates GABAergic activity in the nucleus accumbens of freely moving rats. Neurochemistry international. vol 90. 2016-09-20. PMID:26449310. |
deep brain stimulation (dbs) of the nucleus accumbens (nac) is an effective treatment option for those affected by obsessive compulsive disorder, who do not respond to pharmacological treatment strategies. |
2016-09-20 |
2023-08-13 |
rat |
| M-P Cossette, K Conover, P Shizga. The neural substrates for the rewarding and dopamine-releasing effects of medial forebrain bundle stimulation have partially discrepant frequency responses. Behavioural brain research. vol 297. 2016-09-20. PMID:26477378. |
psychometric current-frequency trade-off functions were derived from icss performance, and chemometric trade-off functions were derived from stimulation-induced dopamine transients in the nucleus accumbens (nac) shell, measured by means of fast-scan cyclic voltammetry. |
2016-09-20 |
2023-08-13 |
human |
| Kia J Jackson, Pretal P Muldoon, Carrie Walters, Mohamad Imad Dama. Neuronal calcium/calmodulin-dependent protein kinase II mediates nicotine reward in the conditioned place preference test in mice. Behavioural pharmacology. vol 27. issue 1. 2016-09-19. PMID:26292186. |
further, we assessed camkii activity in the ventral tegmental area (vta), nucleus accumbens (nac), prefrontal cortex, and hippocampus after nicotine cpp and found significant increases in camkii activity in the mouse vta and nac that were blocked by camkii antagonists. |
2016-09-19 |
2023-08-13 |
mouse |
| Ebrahim Khodayar, Shahrbanoo Oryan, Mohammad Nasehi, Mohammad-Reza Zarrindas. Effect of nucleus accumbens shell 5-HT4 receptors on the impairment of ACPA-induced emotional memory consolidation in male Wistar rats. Behavioural pharmacology. vol 27. issue 1. 2016-09-19. PMID:26340366. |
the present study investigates the effects of 5-ht4 receptors of the nucleus accumbens (nac) shell on the impairment of emotional memory consolidation induced by cannabinoid cb1 receptor stimulation. |
2016-09-19 |
2023-08-13 |
rat |
| Achikam Haim, Christopher Albin-Brooks, Morgan Sherer, Emily Mills, Benedetta Leune. The effects of gestational stress and Selective Serotonin reuptake inhibitor antidepressant treatment on structural plasticity in the postpartum brain--A translational model for postpartum depression. Hormones and behavior. vol 77. 2016-09-15. PMID:25997412. |
moreover, the effect of gestational stress on postpartum mood is accompanied by structural modifications within the nucleus accumbens (nac) and the medial prefrontal cortex (mpfc)-limbic regions that have been linked to ppd. |
2016-09-15 |
2023-08-13 |
rat |
| Jochen De Vry, Tim Vanmierlo, Pilar Martínez-Martínez, Mario Losen, Yasin Temel, Janneke Boere, Gunter Kenis, Thomas Steckler, Harry W M Steinbusch, Marc De Baets, Jos Prickaert. TrkB in the hippocampus and nucleus accumbens differentially modulates depression-like behavior in mice. Behavioural brain research. vol 296. 2016-09-15. PMID:26315459. |
brain-derived neurotrophic factor (bdnf) exerts antidepressant-like effects in the hippocampus and pro-depressant effects in the nucleus accumbens (nac). |
2016-09-15 |
2023-08-13 |
mouse |
| Jintao Wu, Dexiao Zhu, Jing Zhang, Guibao Li, Zengxun Liu, Jinhao Su. Melatonin treatment during the incubation of sensitization attenuates methamphetamine-induced locomotor sensitization and MeCP2 expression. Progress in neuro-psychopharmacology & biological psychiatry. vol 65. 2016-09-14. PMID:26416230. |
surprisingly, correlation analysis suggested significant correlation between mecp2 expression in the nucleus accumbens (nac) and locomotion in both saline control and vehicle treated mice, but not in melatonin treated ones. |
2016-09-14 |
2023-08-13 |
mouse |
| T J Martin, T Sexton, S A Kim, A L Severino, C M Peters, L J Young, S R Childer. Regional differences in mu and kappa opioid receptor G-protein activation in brain in male and female prairie voles. Neuroscience. vol 311. 2016-09-14. PMID:26523979. |
damgo produced higher stimulation in the core versus the shell of the nucleus accumbens (nac) in females, while the distribution of u-50,488h stimulation was the opposite. |
2016-09-14 |
2023-08-13 |
mouse |
| Jen-Hau Yang, Ruey-Ming Lia. Dissociable contribution of nucleus accumbens and dorsolateral striatum to the acquisition of risk choice behavior in the rat. Neurobiology of learning and memory. vol 126. 2016-09-14. PMID:26551356. |
while a growing body of research has suggested that the mesocorticolimbic dopamine systems play a key role in decision making under risk, how the nucleus accumbens (nac) is involved in the acquisition of risk choice behavior remains unclear. |
2016-09-14 |
2023-08-13 |
rat |
| Kelly Lei, Scott A Wegner, Ji Hwan Yu, Arisa Mototake, Bing Hu, Frederic W Hop. Nucleus Accumbens Shell and mPFC but Not Insula Orexin-1 Receptors Promote Excessive Alcohol Drinking. Frontiers in neuroscience. vol 10. 2016-09-14. PMID:27625592. |
given the importance of the nucleus accumbens (nac) and anterior insular cortex (ains) in driving many addictive behaviors, including ox1rs within these regions, we examined the importance of ox1rs in these regions on excessive alcohol drinking in c57bl/6 mice during limited-access alcohol drinking in the dark cycle. |
2016-09-14 |
2023-08-13 |
mouse |
| Oscar V Torres, Michael T McCoy, Bruce Ladenheim, Subramaniam Jayanthi, Christie Brannock, Ingrid Tulloch, Irina N Krasnova, Jean Lud Cade. CAMKII-conditional deletion of histone deacetylase 2 potentiates acute methamphetamine-induced expression of immediate early genes in the mouse nucleus accumbens. Scientific reports. vol 5. 2016-09-13. PMID:26300473. |
methamphetamine (meth) produces increases in the expression of immediate early genes (iegs) and of histone deacetylase 2 (hdac2) in the rat nucleus accumbens (nac). |
2016-09-13 |
2023-08-13 |
mouse |
| Chi-Ya Kao, Zhisong He, Kathrin Henes, John M Asara, Christian Webhofer, Michaela D Filiou, Philipp Khaitovich, Carsten T Wotjak, Christoph W Turc. Fluoxetine Treatment Rescues Energy Metabolism Pathway Alterations in a Posttraumatic Stress Disorder Mouse Model. Molecular neuropsychiatry. vol 2. issue 1. 2016-09-08. PMID:27606320. |
in silico pathway analyses revealed an upregulation of the citric acid cycle pathway in prl, and downregulation in acc and nucleus accumbens (nac). |
2016-09-08 |
2023-08-13 |
mouse |
| Matthew M Hurley, Brian Maunze, Megan E Block, Mogen M Frenkel, Michael J Reilly, Eugene Kim, Yao Chen, Yan Li, David A Baker, Qing-Song Liu, SuJean Cho. Pituitary Adenylate-Cyclase Activating Polypeptide Regulates Hunger- and Palatability-Induced Binge Eating. Frontiers in neuroscience. vol 10. 2016-09-06. PMID:27597817. |
in contrast, inhibition of the nucleus accumbens (nac), through local microinjections of gaba receptor agonists baclofen and muscimol, decreased hedonic feeding without altering homeostatic feeding. |
2016-09-06 |
2023-08-13 |
rat |
| Cynthia El Hage, Anne-Marie Bédard, Anne-Noël Samah. Antipsychotic treatment leading to dopamine supersensitivity persistently alters nucleus accumbens function. Neuropharmacology. vol 99. 2016-08-30. PMID:25823912. |
here we investigated the role of striatal subregions [nucleus accumbens (nac) and caudate-putamen (cpu)] in the expression of antipsychotic-induced dopamine supersensitivity. |
2016-08-30 |
2023-08-13 |
rat |
| Laurie P Sutton, Marc G Caro. Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine. Neuropharmacology. vol 99. 2016-08-30. PMID:26314207. |
specifically, cocaine treatment increased the phosphorylation on residues thr2446 and ser2481 but not on ser2448 in the nucleus accumbens (nac) and that this increase in phosphorylated mtor levels was also apparent when complexed with its binding partner raptor. |
2016-08-30 |
2023-08-13 |
mouse |
| M A De Luca, Z Bimpisidis, M Melis, M Marti, P Caboni, V Valentini, G Margiani, N Pintori, I Polis, G Marsicano, L H Parsons, G Di Chiar. Stimulation of in vivo dopamine transmission and intravenous self-administration in rats and mice by JWH-018, a Spice cannabinoid. Neuropharmacology. vol 99. 2016-08-30. PMID:26327678. |
in order to investigate the neurobiological substrates of jwh-018 actions, we studied by microdialysis in freely moving rats the effect of jwh-018 on extracellular dopamine (da) levels in the nucleus accumbens (nac) shell and core and in the medial prefrontal cortex (mpfc). |
2016-08-30 |
2023-08-13 |
mouse |
| A L Northcutt, M R Hutchinson, X Wang, M V Baratta, T Hiranita, T A Cochran, M B Pomrenze, E L Galer, T A Kopajtic, C M Li, J Amat, G Larson, D C Cooper, Y Huang, C E O'Neill, H Yin, N R Zahniser, J L Katz, K C Rice, S F Maier, R K Bachtell, L R Watkin. DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling. Molecular psychiatry. vol 20. issue 12. 2016-08-29. PMID:25644383. |
resulting increases in extracellular dopamine in the nucleus accumbens (nac) are traditionally thought to result from cocaine's ability to block dopamine transporters (dats). |
2016-08-29 |
2023-08-13 |
Not clear |
| Kazuya Toriumi, Takayoshi Mamiya, Ziyu Song, Tatsuki Honjo, Hiroyuki Watanabe, Junko Tanaka, Mizuki Kondo, Akihiro Mouri, Hyoung-Chun Kim, Atsumi Nitta, Takeshi Fukushima, Toshitaka Nabeshim. Deletion of SHATI/NAT8L decreases the N-acetylaspartate content in the brain and induces behavioral deficits, which can be ameliorated by administering N-acetylaspartate. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 11. 2016-08-26. PMID:26361739. |
in particular, dopaminergic turnover increased in the nucleus accumbens (nac) in shati(-/-) mice, suggesting activation of the dopaminergic system. |
2016-08-26 |
2023-08-13 |
mouse |
| Craig T Werner, Mike Milovanovic, Daniel T Christian, Jessica A Loweth, Marina E Wol. Response of the Ubiquitin-Proteasome System to Memory Retrieval After Extended-Access Cocaine or Saline Self-Administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 13. 2016-08-25. PMID:26044907. |
we found that retrieval of cocaine- and saline-associated memories produced similar increases in polyubiquitinated proteins in the nucleus accumbens (nac), compared with rats that did not undergo a seeking/retrieval test. |
2016-08-25 |
2023-08-13 |
rat |