| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jessica R Gugusheff, Sung Eun Bae, Alexandra Rao, Iain J Clarke, Lucilla Poston, Paul D Taylor, Clive W Coen, Beverly S Muhlhausle. Sex and age-dependent effects of a maternal junk food diet on the mu-opioid receptor in rat offspring. Behavioural brain research. vol 301. 2016-10-20. PMID:26718219. |
this study aimed to determine the impact of a maternal junk food (jf) diet on mu-opioid receptor (mur) expression and ligand binding in two key regions of the reward pathway, the nucleus accumbens (nac) and the ventral tegmental area (vta) in rats during the early suckling (postnatal day (pnd) 1 and 7) and late suckling/early post-weaning (pnd 21 and 28) periods. |
2016-10-20 |
2023-08-13 |
rat |
| Y Li, S Ge, N Li, L Chen, S Zhang, J Wang, H Wu, X Wang, X Wan. NMDA and dopamine D1 receptors within NAc-shell regulate IEG proteins expression in reward circuit during cocaine memory reconsolidation. Neuroscience. vol 315. 2016-10-19. PMID:26674058. |
the nucleus accumbens (nac) has been well recognized as a pathway component that can prevent drug relapse, although the mechanism underlying this function is poorly understood. |
2016-10-19 |
2023-08-13 |
Not clear |
| S Kedracka-Krok, B Swiderska, U Jankowska, B Skupien-Rabian, J Solich, M Dziedzicka-Wasylewsk. Stathmin reduction and cytoskeleton rearrangement in rat nucleus accumbens in response to clozapine and risperidone treatment - Comparative proteomic study. Neuroscience. vol 316. 2016-10-18. PMID:26708747. |
the complex network of anatomical connections of the nucleus accumbens (nac) makes it an interface responsible for the selection and integration of cognitive and affective information to modulate appetitive or aversively motivated behaviour. |
2016-10-18 |
2023-08-13 |
rat |
| Guohua Song, Tanseli Nesil, Junran Cao, Zhongli Yang, Sulie L Chang, Ming D L. Nicotine mediates expression of genes related to antioxidant capacity and oxidative stress response in HIV-1 transgenic rat brain. Journal of neurovirology. vol 22. issue 1. 2016-10-14. PMID:26306689. |
the purpose of this study was to determine the effect of nicotine on expression of genes related to the glutathione (gsh)-centered antioxidant system and oxidative stress in the nucleus accumbens (nac) and ventral tegmental area (vta) of hiv-1 transgenic (hiv-1tg) and f344 control rats. |
2016-10-14 |
2023-08-13 |
rat |
| K Berghauzen-Maciejewska, J Wardas, B Kosmowska, H Domin, M Śmiałowska, U Głowacka, K Ossowsk. Adaptive down-regulation of the serotonin transporter in the 6-hydroxydopamine-induced rat model of preclinical stages of Parkinson's disease and after chronic pramipexole treatment. Neuroscience. vol 314. 2016-10-13. PMID:26628402. |
intrastriatal 6-ohda injections decreased the number of dopaminergic, but not serotonergic neurons in the dr. 6-ohda reduced the dat binding in the cp, and sert binding in the nigrostriatal system (cp, substantia nigra (sn)), limbic system (ventral tegmental area (vta), nucleus accumbens (nac), amygdala, prefrontal cortex (pfcx), habenula, hippocampus) and dr. a significant positive correlation was found between dat and sert binding in the cp. |
2016-10-13 |
2023-08-13 |
rat |
| Cecile Hryhorczuk, Marc Florea, Demetra Rodaros, Isabelle Poirier, Caroline Daneault, Christine Des Rosiers, Andreas Arvanitogiannis, Thierry Alquier, Stephanie Fulto. Dampened Mesolimbic Dopamine Function and Signaling by Saturated but not Monounsaturated Dietary Lipids. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 3. 2016-10-06. PMID:26171719. |
we sought to determine the impact of prolonged ad libitum intake of diets rich in saturated or monounsaturated fat, separate from metabolic signals associated with increased adiposity, on dopamine (da)-dependent behaviors and to identify pertinent signaling changes in the nucleus accumbens (nac). |
2016-10-06 |
2023-08-13 |
human |
| Samantha M Fortin, Elena H Chartoff, Mitchell F Roitma. The Aversive Agent Lithium Chloride Suppresses Phasic Dopamine Release Through Central GLP-1 Receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 3. 2016-10-06. PMID:26211731. |
unconditioned rewarding stimuli evoke phasic increases in dopamine concentration in the nucleus accumbens (nac) while discrete aversive stimuli elicit pauses in dopamine neuron firing and reductions in nac dopamine concentration. |
2016-10-06 |
2023-08-13 |
rat |
| Rhona B C Clarke, Bo Söderpalm, Amir Lotfi, Mia Ericson, Louise Adermar. Involvement of Inhibitory Receptors in Modulating Dopamine Signaling and Synaptic Activity Following Acute Ethanol Exposure in Striatal Subregions. Alcoholism, clinical and experimental research. vol 39. issue 12. 2016-10-06. PMID:26614538. |
alcohol acts on both inhibitory and excitatory receptor systems resulting in a net increase in dopamine output in the ventral striatum (nucleus accumbens [nac]), which is implicated in drug reward. |
2016-10-06 |
2023-08-13 |
Not clear |
| Yukihiko Shirayama, Chun Yang, Ji-chun Zhang, Qian Ren, Wei Yao, Kenji Hashimot. Alterations in brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain regions of a learned helplessness rat model and the antidepressant effects of a TrkB agonist and antagonist. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 12. 2016-10-05. PMID:26419294. |
lh rats showed a reduction of bdnf in the medial prefrontal cortex (mpfc), ca3, and dentate gyrus (dg) of the hippocampus, whereas lh rats showed an increase in bdnf in the nucleus accumbens (nac). |
2016-10-05 |
2023-08-13 |
rat |
| Mitra Heshmati, Sam A Golden, Madeline L Pfau, Daniel J Christoffel, Elena L Seeley, Michael E Cahill, Lena A Khibnik, Scott J Russ. Mefloquine in the nucleus accumbens promotes social avoidance and anxiety-like behavior in mice. Neuropharmacology. vol 101. 2016-10-05. PMID:26471420. |
direct infusion of mefloquine into the nucleus accumbens (nac), a key brain reward region, increased stress-induced social avoidance and anxiety behavior. |
2016-10-05 |
2023-08-13 |
mouse |
| Max F Oginsky, Joel D Maust, John T Corthell, Carrie R Ferrari. Enhanced cocaine-induced locomotor sensitization and intrinsic excitability of NAc medium spiny neurons in adult but not in adolescent rats susceptible to diet-induced obesity. Psychopharmacology. vol 233. issue 5. 2016-09-30. PMID:26612617. |
basal and diet-induced differences in mesolimbic function, particularly within the nucleus accumbens (nac), may contribute to human obesity; these differences may be more pronounced in susceptible populations. |
2016-09-30 |
2023-08-13 |
human |
| Gislaine Z Réus, Helena M Abaleira, Stephanie E Titus, Camila O Arent, Monique Michels, Jaine R da Luz, Maria Augusta B dos Santos, Anelise S Carlessi, Beatriz I Matias, Livia Bruchchen, Amanda V Steckert, Luciane B Ceretta, Felipe Dal-Pizzol, João Queved. Effects of ketamine administration on the phosphorylation levels of CREB and TrKB and on oxidative damage after infusion of MEK inhibitor. Pharmacological reports : PR. vol 68. issue 1. 2016-09-29. PMID:26721370. |
thus, this study evaluated the effects of the administration of ketamine on the phosphorylation of trkb and creb, and oxidative stress parameters in the prefrontal cortex (pfc), hippocampus, amygdala, and nucleus accumbens (nac) rats, after the inhibition of mapk pathway (pd184161). |
2016-09-29 |
2023-08-13 |
rat |
| Dana M LeBlanc, M Adrienne McGinn, Christy A Itoga, Scott Edward. The affective dimension of pain as a risk factor for drug and alcohol addiction. Alcohol (Fayetteville, N.Y.). vol 49. issue 8. 2016-09-27. PMID:26008713. |
brain stress- and reinforcement-related regions such as the central amygdala (cea), prefrontal cortex (pfc), and nucleus accumbens (nac) also serve as central processors of ascending nociceptive input. |
2016-09-27 |
2023-08-13 |
Not clear |
| Dan P Covey, Jennifer M Wenzel, Joseph F Chee. Cannabinoid modulation of drug reward and the implications of marijuana legalization. Brain research. vol 1628. issue Pt A. 2016-09-27. PMID:25463025. |
presynaptic cb1 receptors control midbrain dopamine neuron activity and thereby shape phasic dopamine release in target regions, particularly the nucleus accumbens (nac). |
2016-09-27 |
2023-08-13 |
Not clear |
| Venkata Siva Sai Sujith Sajja, W Brad Hubbard, Christina S Hall, Farhad Ghoddoussi, Matthew P Galloway, Pamela J VandeVor. Enduring deficits in memory and neuronal pathology after blast-induced traumatic brain injury. Scientific reports. vol 5. 2016-09-26. PMID:26537106. |
here, we used behavioral assays, immmunohistochemistry and neurochemistry in limbic areas such as the amygdala (amy), hippocampus (hipp), nucleus accumbens (nac), and prefrontal cortex (pfc), to determine the long-term effects of a single blast exposure. |
2016-09-26 |
2023-08-13 |
Not clear |
| W T Doucette, J Y Khokhar, A I Gree. Nucleus accumbens deep brain stimulation in a rat model of binge eating. Translational psychiatry. vol 5. 2016-09-26. PMID:26670280. |
we hypothesized that be rats receiving high-frequency dbs in the nucleus accumbens (nac) core would have reduced binge sizes compared with sham stimulation in both a 'chronic be' model as well as in a 'relapse to chronic be' model. |
2016-09-26 |
2023-08-13 |
rat |
| Yi Zhang, Xiongzhao Zhu, Can Huang, Xiuwu Zhan. Molecular changes in the medial prefrontal cortex and nucleus accumbens are associated with blocking the behavioral sensitization to cocaine. Scientific reports. vol 5. 2016-09-23. PMID:26538265. |
previous studies have demonstrated that cocaine-induced behavioral sensitization is associated with persistent functional and structural alterations in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac); however, the molecular mechanisms underlying these changes have not been elucidated. |
2016-09-23 |
2023-08-13 |
rat |
| Gongying Li, Yanmei Wang, Min Yan, Yunshuai Xu, Xiuli Song, Qingqing Li, Jinxiang Zhang, Hongxia Ma, Yili W. Inhibition of actin polymerization in the NAc shell inhibits morphine-induced CPP by disrupting its reconsolidation. Scientific reports. vol 5. 2016-09-23. PMID:26538334. |
in the present study, we found that inhibiting actin polymerization in the nucleus accumbens (nac) shell, but not the nac core, abolishes morphine-induced conditioned place preference (cpp) by disrupting its reconsolidation in rats. |
2016-09-23 |
2023-08-13 |
rat |
| Lauren N Beloate, Peyton W Weems, Graham R Casey, Ian C Webb, Lique M Coole. Nucleus accumbens NMDA receptor activation regulates amphetamine cross-sensitization and deltaFosB expression following sexual experience in male rats. Neuropharmacology. vol 101. 2016-09-22. PMID:26391065. |
moreover, sexual experience induces neural plasticity within the nucleus accumbens (nac), including induction of deltafosb, which plays a key role in amph reward cross-sensitization. |
2016-09-22 |
2023-08-13 |
rat |
| Fatemeh Yazdi, Mahboubeh Jahangirvand, Amir-Hossein Pirasteh, Marzieh Moradi, Abbas Haghparas. Functional interaction between OX2 and CB1 receptors in the ventral tegmental area and the nucleus accumbens in response to place preference induced by chemical stimulation of the lateral hypothalamus. Pharmacology, biochemistry, and behavior. vol 139. issue Pt A. 2016-09-22. PMID:26494513. |
orexinergic projections derived from the lateral hypothalamus (lh) to the ventral tegmental area (vta) and the nucleus accumbens (nac), play a key role in the acquisition of conditioned place preference (cpp) induced by lh stimulation. |
2016-09-22 |
2023-08-13 |
Not clear |