| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gongying Li, Yanmei Wang, Min Yan, Hongxia Ma, Yanjie Gao, Zexuan Li, Changqi Li, Hongjun Tian, Chuanjun Zhu. Time-dependent co-relation of BDNF and CREB mRNAs in adult rat brains following acute psychological stress in the communication box paradigm. Neuroscience letters. vol 624. 2017-06-06. PMID:27132084. |
the mrna levels of bdnf and creb were significantly decreased, then gradually recovered over 24h to maximum levels in the hippocampus (ca1 region), prefrontal cortex (pfc), central amygdaloid nuclei (ag), shell of accumbens nucleus (nac), periaqueductal gray (pag) and ventral tegmental area, except for the ventral tegmental area (vta). |
2017-06-06 |
2023-08-13 |
human |
| M F Lazenka, J A Suyama, C T Bauer, M L Banks, S S Negu. Sex differences in abuse-related neurochemical and behavioral effects of 3,4-methylenedioxymethamphetamine (MDMA) in rats. Pharmacology, biochemistry, and behavior. vol 152. 2017-06-01. PMID:27566288. |
to evaluate potential for sex differences in abuse-related mdma effects, the present study compared mdma effects on intracranial self-stimulation (icss) and on in vivo microdialysis measurements of da or 5ht in the nucleus accumbens (nac) in female and male sprague-dawley rats. |
2017-06-01 |
2023-08-13 |
rat |
| Haitao Zhang, Dong Jia, Yuan Wang, Liang Qu, Xuelian Wang, Jian Song, Lijun Heng, Guodong Ga. Enhanced ability of TRPV1 channels in regulating glutamatergic transmission after repeated morphine exposure in the nucleus accumbens of rat. Brain research. vol 1660. 2017-05-25. PMID:28188777. |
glutamatergic projections to nucleus accumbens (nac) drive drug-seeking behaviors during opioids withdrawal. |
2017-05-25 |
2023-08-13 |
rat |
| Anthony Purgianto, Jessica A Loweth, Julia J Miao, Mike Milovanovic, Marina E Wol. Surface expression of GABAA receptors in the rat nucleus accumbens is increased in early but not late withdrawal from extended-access cocaine self-administration. Brain research. vol 1642. 2017-05-23. PMID:27060767. |
it is well established that cocaine-induced changes in glutamate receptor expression in the nucleus accumbens (nac) play a significant role in animal models of cocaine addiction. |
2017-05-23 |
2023-08-13 |
rat |
| P De Ron, S Dremier, P Winlow, A Jenkins, E Hanon, A Nogueira da Cost. Correlating behaviour and gene expression endpoints in the dopaminergic system after modafinil administration in mouse. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 4. 2017-05-03. PMID:26875113. |
whole genome expression and qrt-pcr analysis were performed on the ventral tegmental area (vta), nucleus accumbens (nac) and prefrontal cortex (pfc) of modafinil-treated and control animals. |
2017-05-03 |
2023-08-13 |
mouse |
| Lena A Khibnik, Michael Beaumont, Marie Doyle, Mitra Heshmati, Paul A Slesinger, Eric J Nestler, Scott J Russ. Stress and Cocaine Trigger Divergent and Cell Type-Specific Regulation of Synaptic Transmission at Single Spines in Nucleus Accumbens. Biological psychiatry. vol 79. issue 11. 2017-05-01. PMID:26164802. |
repeated exposure to cocaine or social stress leads to lasting structural and functional synaptic alterations in medium spiny neurons (msns) of nucleus accumbens (nac). |
2017-05-01 |
2023-08-13 |
Not clear |
| Elham Charmchi, Morteza Zendehdel, Abbas Haghparas. The effect of forced swim stress on morphine sensitization: Involvement of D1/D2-like dopamine receptors within the nucleus accumbens. Progress in neuro-psychopharmacology & biological psychiatry. vol 70. 2017-04-12. PMID:27235796. |
nucleus accumbens (nac) plays an essential role in morphine sensitization and suppression of pain. |
2017-04-12 |
2023-08-13 |
rat |
| Michael De Santis, Jiamei Lian, Xu-Feng Huang, Chao Den. Early Antipsychotic Treatment in Juvenile Rats Elicits Long-Term Alterations to the Dopamine Neurotransmitter System. International journal of molecular sciences. vol 17. issue 11. 2017-04-04. PMID:27879654. |
olanzapine decreased pfc p-th levels and increased d₂ receptor expression in the pfc and nucleus accumbens (nac) in females only. |
2017-04-04 |
2023-08-13 |
rat |
| Jamie H Rose, Anushree N Karkhanis, Björn Steiniger-Brach, Sara R Jone. Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure. International journal of molecular sciences. vol 17. issue 8. 2017-03-28. PMID:27472317. |
preclinical data support a role for nucleus accumbens (nac) κ opioid receptors (kor) in chronic intermittent ethanol (cie) exposure-induced increases in ethanol intake. |
2017-03-28 |
2023-08-13 |
mouse |
| Teruhiro Okuyama, Takashi Kitamura, Dheeraj S Roy, Shigeyoshi Itohara, Susumu Tonegaw. Ventral CA1 neurons store social memory. Science (New York, N.Y.). vol 353. issue 6307. 2017-03-27. PMID:27708103. |
here, we show that ventral hippocampal ca1 (vca1) neurons of a mouse and their projections to nucleus accumbens (nac) shell play a necessary and sufficient role in social memory. |
2017-03-27 |
2023-08-13 |
mouse |
| Jun Ping Cao, Hong Jun Wang, Li Li, Su Ming Zhan. The effects of morphine treatment on the NCAM and its signaling in the MLDS of rats. Drug and chemical toxicology. vol 39. issue 4. 2017-03-10. PMID:26821693. |
twelve hours after the last injection, animals were sacrificed and the tissues of ventral tegmental area (vta), prefrontal cortex (pfc) and nucleus accumbens (nac) were punched out to examine the expression of ncam or its signaling level. |
2017-03-10 |
2023-08-13 |
human |
| Bo Pan, Jiamei Lian, Xu-Feng Huang, Chao Den. Aripiprazole Increases the PKA Signalling and Expression of the GABAA Receptor and CREB1 in the Nucleus Accumbens of Rats. Journal of molecular neuroscience : MN. vol 59. issue 1. 2017-03-10. PMID:26894264. |
the levels of pka-cα and p-pka in the prefrontal cortex (pfc), nucleus accumbens (nac) and caudate putamen (cpu) were detected by western blots. |
2017-03-10 |
2023-08-13 |
rat |
| Morgan H James, Rikki K Quinn, Lin Kooi Ong, Emily M Levi, Doug W Smith, Phillip W Dickson, Christopher V Daya. Rapamycin reduces motivated responding for cocaine and alters GluA1 expression in the ventral but not dorsal striatum. European journal of pharmacology. vol 784. 2017-03-02. PMID:27181066. |
these behavioral effects are associated with decreased mtorc1 activity and synaptic protein translation in the nucleus accumbens (nac) and point to a possible therapeutic role for rapamycin in the treatment of addiction. |
2017-03-02 |
2023-08-13 |
Not clear |
| Benfu Wang, Xiaowei Yang, Anna Sun, Lanman Xu, Sicong Wang, Wenxuan Lin, Miaojun Lai, Huaqiang Zhu, Wenhua Zhou, Qingquan Lia. Extracellular Signal-Regulated Kinase in Nucleus Accumbens Mediates Propofol Self-Administration in Rats. Neuroscience bulletin. vol 32. issue 6. 2017-02-27. PMID:27783327. |
the purpose of this study was to investigate the role of extracellular signal-regulated kinase (erk) signal transduction pathways in the nucleus accumbens (nac) in propofol self-administration. |
2017-02-27 |
2023-08-13 |
rat |
| Ali Siahposht-Khachaki, Zahra Fatahi, Asal Yans, Fariba Khodagholi, Abbas Haghparas. Involvement of AMPA/Kainate Glutamate Receptor in the Extinction and Reinstatement of Morphine-Induced Conditioned Place Preference: A Behavioral and Molecular Study. Cellular and molecular neurobiology. vol 37. issue 2. 2017-02-23. PMID:27053349. |
therefore, in the present study, we investigated the changes in phosphorylated creb (p-creb) and c-fos induction within the nucleus accumbens (nac), hip, and pfc after intracerebroventricular (icv) administration of different doses of cnqx or vehicle during extinction period or reinstatement of morphine-induced cpp. |
2017-02-23 |
2023-08-13 |
rat |
| Nesrin F Basaran, R Levent Buyukuysal, M Sertac Yilmaz, Sami Aydin, Sinan Cavun, William R Millingto. The effect of Gly-Gln [ß-endorphin30-31] on morphine-evoked serotonin and GABA efflux in the nucleus accumbens of conscious rats. Neuropeptides. vol 58. 2017-02-13. PMID:26861257. |
in an earlier study, we found that gly-gln inhibits morphine-induced dopamine efflux in the nucleus accumbens (nac), consistent with its ability to inhibit morphine reward. |
2017-02-13 |
2023-08-13 |
rat |
| Jennifer M Bossert, Sweta Adhikary, Robyn St Laurent, Nathan J Marchant, Hui-Ling Wang, Marisela Morales, Yavin Shaha. Role of projections from ventral subiculum to nucleus accumbens shell in context-induced reinstatement of heroin seeking in rats. Psychopharmacology. vol 233. issue 10. 2017-02-10. PMID:26344108. |
we previously demonstrated that the projections from ventral medial prefrontal cortex (vmpfc) to nucleus accumbens (nac) shell play a role in this reinstatement. |
2017-02-10 |
2023-08-13 |
rat |
| Jacob T Beckley, Patrick K Randall, Rachel J Smith, Benjamin A Hughes, Peter W Kalivas, John J Woodwar. Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene. Addiction biology. vol 21. issue 3. 2017-01-10. PMID:25752326. |
however, little is known about how toluene affects neurons within the nucleus accumbens (nac), a brain region within the basal ganglia that mediates goal-directed behaviors and is implicated in the development and maintenance of addictive behaviors. |
2017-01-10 |
2023-08-13 |
rat |
| Joachim D Uys, Natalie S McGuier, Justin T Gass, William C Griffin, Lauren E Ball, Patrick J Mulhollan. Chronic intermittent ethanol exposure and withdrawal leads to adaptations in nucleus accumbens core postsynaptic density proteome and dendritic spines. Addiction biology. vol 21. issue 3. 2017-01-10. PMID:25787124. |
clinical and pre-clinical models provide strong evidence for chronic ethanol-associated alterations in glutamatergic signaling and impaired synaptic plasticity in the nucleus accumbens (nac). |
2017-01-10 |
2023-08-13 |
mouse |
| Sema G Quadir, Jaqueline Rocha Borges Dos Santos, Rianne R Campbell, Melissa G Wroten, Nimrita Singh, John J Holloway, Sukhmani K Bal, Rosana Camarini, Karen K Szumlinsk. Homer2 regulates alcohol and stress cross-sensitization. Addiction biology. vol 21. issue 3. 2017-01-10. PMID:25916683. |
we also employed immunoblotting to relate the expression of glutamate receptor-related proteins within subregions of the nucleus accumbens (nac) to the manifestation of behavioral cross-sensitization. |
2017-01-10 |
2023-08-13 |
mouse |