| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jacob T Beckley, Sophie Laguesse, Khanhky Phamluong, Nadege Morisot, Scott A Wegner, Dorit Ro. The First Alcohol Drink Triggers mTORC1-Dependent Synaptic Plasticity in Nucleus Accumbens Dopamine D1 Receptor Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 3. 2016-05-27. PMID:26791202. |
we found that the first binge-drinking alcohol session produced enduring enhancement of excitatory synaptic transmission onto dopamine d1 receptor-expressing neurons (d1+ neurons) in the nucleus accumbens (nac) shell but not the core in mice, which required d1 receptors (d1rs) and mechanistic target of rapamycin complex 1 (mtorc1). |
2016-05-27 |
2023-08-13 |
mouse |
| b' C\\xc3\\xa9sar Quiroz, Marco Orr\\xc3\\xba, William Rea, Andr\\xc3\\xa9s Ciudad-Roberts, Gabriel Yepes, Jonathan P Britt, Sergi Ferr\\xc3\\xa. Local Control of Extracellular Dopamine Levels in the Medial Nucleus Accumbens by a Glutamatergic Projection from the Infralimbic Cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 3. 2016-05-27. PMID:26791215.' |
it is generally assumed that infralimbic cortex (ilc) and prelimbic cortex, two adjacent areas of the medial prefrontal cortex (mpfc) in rodents, provide selective excitatory glutamatergic inputs to the nucleus accumbens (nac) shell and core, respectively. |
2016-05-27 |
2023-08-13 |
Not clear |
| C Biesdorf, A-L Wang, B Topic, D Petri, H Milani, J P Huston, M A de Souza Silv. Dopamine in the nucleus accumbens core, but not shell, increases during signaled food reward and decreases during delayed extinction. Neurobiology of learning and memory. vol 123. 2016-05-26. PMID:26071677. |
microdialysis studies in rat have generally shown that appetitive stimuli release dopamine (da) in the nucleus accumbens (nac) shell and core. |
2016-05-26 |
2023-08-13 |
rat |
| Mohammed Mamdani, Vernell Williamson, Gowon O McMichael, Tana Blevins, Fazil Aliev, Amy Adkins, Laura Hack, Tim Bigdeli, Andrew D van der Vaart, Bradley Todd Web, Silviu-Alin Bacanu, Gursharan Kalsi, Kenneth S Kendler, Michael F Miles, Danielle Dick, Brien P Riley, Catherine Dumur, Vladimir I Vladimiro. Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence. PloS one. vol 10. issue 9. 2016-05-26. PMID:26381263. |
after performing weighted gene co-expression network analyses (wgcna) on genome-wide mrna and microrna (mirna) expression in nucleus accumbens (nac) of subjects with alcohol dependence (ad; n = 18) and of matched controls (n = 18), six mrna and three mirna modules significantly correlated with ad were identified (bonferoni-adj. |
2016-05-26 |
2023-08-13 |
human |
| Marzieh Moradi, Mohamadreza Yazdanian, Abbas Haghparas. Role of dopamine D2-like receptors within the ventral tegmental area and nucleus accumbens in antinociception induced by lateral hypothalamus stimulation. Behavioural brain research. vol 292. 2016-05-25. PMID:26166189. |
functional interaction between the lh and the main area of the mesolimbic pathway such as the ventral tegmental area (vta) and the nucleus accumbens (nac) implicates in pain modulation. |
2016-05-25 |
2023-08-13 |
rat |
| Céline Devroye, Adeline Cathala, Barbara Di Marco, Filippo Caraci, Filippo Drago, Pier Vincenzo Piazza, Umberto Spampinat. Central serotonin(2B) receptor blockade inhibits cocaine-induced hyperlocomotion independently of changes of subcortical dopamine outflow. Neuropharmacology. vol 97. 2016-05-24. PMID:26116760. |
in the present study, we assessed the effect of two selective 5-ht2br antagonists, rs 127445 and ly 266097, on cocaine-induced hyperlocomotion and dopamine (da) outflow in the nucleus accumbens (nac) and the dorsal striatum of freely moving rats. |
2016-05-24 |
2023-08-13 |
rat |
| Alqassem Y Hakami, Alaa M Hammad, Youssef Sar. Effects of Amoxicillin and Augmentin on Cystine-Glutamate Exchanger and Glutamate Transporter 1 Isoforms as well as Ethanol Intake in Alcohol-Preferring Rats. Frontiers in neuroscience. vol 10. 2016-05-20. PMID:27199635. |
importantly, we recently reported that amoxicillin and augmentin (amoxicillin/clavulanate) upreglulated glt-1 expression in nucleus accumbens (nac) and prefrontal cortex (pfc) as well as reduced ethanol consumption in male p rats. |
2016-05-20 |
2023-08-13 |
rat |
| C R Pinheiro, E Oliveira, A C Manhães, M C Fraga, S Claudio-Neto, V Younes-Rapozo, B M Lotufo, E G Moura, P C Lisbo. Exposure to nicotine increases dopamine receptor content in the mesocorticolimbic pathway of rat dams and offspring during lactation. Pharmacology, biochemistry, and behavior. vol 136. 2016-05-17. PMID:26219213. |
nicotine exposure causes the release of dopamine from the ventral tegmental area (vta) to the nucleus accumbens (nac). |
2016-05-17 |
2023-08-13 |
rat |
| Li Zhu, Jie Zhu, Yufeng Liu, Yanjiong Chen, Yanlin Li, Sisi Chen, Tao Li, Yonghui Dang, Teng Che. Chronic methamphetamine regulates the expression of MicroRNAs and putative target genes in the nucleus accumbens of mice. Journal of neuroscience research. vol 93. issue 10. 2016-05-13. PMID:26031216. |
this study identifies meth-responsive mirnas and their potential effects in the nucleus accumbens (nac) of mice. |
2016-05-13 |
2023-08-13 |
mouse |
| Hao Duan, Ying Zhang, Xiao-Min Zhang, Huan-Huan Xu, Jun Shu, Shi-Lian X. Antinociceptive roles of galanin receptor 1 in nucleus accumbens of rats in a model of neuropathic pain. Journal of neuroscience research. vol 93. issue 10. 2016-05-13. PMID:26104264. |
our previous research has also demonstrated that galanin induces antinociception in the nucleus accumbens (nac) of intact rats. |
2016-05-13 |
2023-08-13 |
rat |
| Melissa A Stouffer, Catherine A Woods, Jyoti C Patel, Christian R Lee, Paul Witkovsky, Li Bao, Robert P Machold, Kymry T Jones, Soledad Cabeza de Vaca, Maarten E A Reith, Kenneth D Carr, Margaret E Ric. Insulin enhances striatal dopamine release by activating cholinergic interneurons and thereby signals reward. Nature communications. vol 6. 2016-05-11. PMID:26503322. |
we report here that insulin can amplify action potential-dependent dopamine (da) release in the nucleus accumbens (nac) and caudate-putamen through an indirect mechanism that involves striatal cholinergic interneurons that express insrs. |
2016-05-11 |
2023-08-13 |
rat |
| Sujan C Das, Bryan K Yamamoto, Alexandar M Hristov, Youssef Sar. Ceftriaxone attenuates ethanol drinking and restores extracellular glutamate concentration through normalization of GLT-1 in nucleus accumbens of male alcohol-preferring rats. Neuropharmacology. vol 97. 2016-05-10. PMID:26002627. |
we have previously reported that chronic ethanol-drinking downregulated glutamate transporter 1 (glt-1) in nucleus accumbens (nac) in male p rats in a manner that was reversed by ceftriaxone treatment. |
2016-05-10 |
2023-08-13 |
rat |
| Gregory N Ruegsegger, Ryan G Toedebusch, Matthew J Will, Frank W Boot. Mu opioid receptor modulation in the nucleus accumbens lowers voluntary wheel running in rats bred for high running motivation. Neuropharmacology. vol 97. 2016-05-10. PMID:26044640. |
aims of this study were 1) to identify intrinsic differences in nucleus accumbens (nac) mrna expression of opioid-related transcripts and 2) to determine if nightly wheel running is differently influenced by bilateral nac injections of either the mu-opioid receptor agonist d-ala2, nme-phe4, glyo5-enkephalin (damgo) (0.25, 2.5 μg/side), or its antagonist, naltrexone (5, 10, 20 μg/side). |
2016-05-10 |
2023-08-13 |
rat |
| L Adermark, J Morud, A Lotfi, S Jonsson, B Söderpalm, M Ericso. Age-contingent influence over accumbal neurotransmission and the locomotor stimulatory response to acute and repeated administration of nicotine in Wistar rats. Neuropharmacology. vol 97. 2016-05-10. PMID:26079444. |
electrophysiological field potential recordings revealed a decline in input/output function in the nucleus accumbens (nac) of animals intermittently treated with nicotine starting at 5 weeks of age, but not in older animals. |
2016-05-10 |
2023-08-13 |
rat |
| Xue-Feng Wang, Jing-Jing Liu, Julia Xia, Ji Liu, Vincent Mirabella, Zhiping P Pan. Endogenous Glucagon-like Peptide-1 Suppresses High-Fat Food Intake by Reducing Synaptic Drive onto Mesolimbic Dopamine Neurons. Cell reports. vol 12. issue 5. 2016-05-09. PMID:26212334. |
we used integrated pathway tracing and synaptic physiology to further demonstrate that activation of glp-1 receptors specifically reduces the excitatory synaptic strength of dopamine (da) neurons within the vta that project to the nucleus accumbens (nac) medial shell. |
2016-05-09 |
2023-08-13 |
Not clear |
| Jakob K Dreyer, Caitlin M Vander Weele, Vedran Lovic, Brandon J Aragon. Functionally Distinct Dopamine Signals in Nucleus Accumbens Core and Shell in the Freely Moving Rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 1. 2016-05-09. PMID:26740653. |
however, this system is complex because firing patterns of these neurons are heterogeneous; subpopulations receive distinct synaptic inputs, and project to anatomically and functionally distinct downstream targets, including the nucleus accumbens (nac) shell and core. |
2016-05-09 |
2023-08-13 |
rat |
| Michael P Saddoris, Xuefei Wang, Jonathan A Sugam, Regina M Carell. Cocaine Self-Administration Experience Induces Pathological Phasic Accumbens Dopamine Signals and Abnormal Incentive Behaviors in Drug-Abstinent Rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 1. 2016-05-09. PMID:26740664. |
chronic exposure to drugs of abuse is linked to long-lasting alterations in the function of limbic system structures, including the nucleus accumbens (nac). |
2016-05-09 |
2023-08-13 |
human |
| Cody A Siciliano, Mark J Ferris, Sara R Jone. Cocaine self-administration disrupts mesolimbic dopamine circuit function and attenuates dopaminergic responsiveness to cocaine. The European journal of neuroscience. vol 42. issue 4. 2016-05-06. PMID:26037018. |
dopaminergic projections from the ventral midbrain to the nucleus accumbens (nac) have long been implicated in encoding associations between reward availability and environmental stimuli. |
2016-05-06 |
2023-08-13 |
rat |
| A Harker, S Raza, K Williamson, B Kolb, R Gib. Preconception paternal stress in rats alters dendritic morphology and connectivity in the brain of developing male and female offspring. Neuroscience. vol 303. 2016-05-06. PMID:26149350. |
the purpose of this study was to examine the effect of preconception paternal stress on developing male and female offspring brain morphology in five brain areas; medial prefrontal cortex (mpfc), orbitofrontal cortex (ofc), parietal cortex (par1), hippocampus (ca1) and nucleus accumbens (nac). |
2016-05-06 |
2023-08-13 |
rat |
| Cristina Miliano, Giovanni Serpelloni, Claudia Rimondo, Maddalena Mereu, Matteo Marti, Maria Antonietta De Luc. Neuropharmacology of New Psychoactive Substances (NPS): Focus on the Rewarding and Reinforcing Properties of Cannabimimetics and Amphetamine-Like Stimulants. Frontiers in neuroscience. vol 10. 2016-05-05. PMID:27147945. |
moreover, the review will include recent data from our lab which links jwh-018, a cb1 and cb2 agonist more potent than Δ(9)-thc, to other cannabinoids with known abuse potential, and to other classes of abused drugs that increase dopamine signaling in the nucleus accumbens (nac) shell. |
2016-05-05 |
2023-08-13 |
Not clear |