| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sophie Laguesse, Nadege Morisot, Jung Hoon Shin, Feng Liu, Martin F Adrover, Samuel A Sakhai, Marcelo F Lopez, Khanhky Phamluong, William C Griffin, Howard C Becker, Kevin J Bender, Veronica A Alvarez, Dorit Ro. Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward. Neuron. vol 96. issue 1. 2017-10-10. PMID:28890345. |
using an unbiased rna-seq approach, we identified prosapip1 as a novel downstream target of mtorc1 whose translation and consequent synaptic protein expression are increased in the nucleus accumbens (nac) of mice excessively consuming alcohol. |
2017-10-10 |
2023-08-13 |
mouse |
| Makoto Taniguchi, Maria B Carreira, Yonatan A Cooper, Ana-Clara Bobadilla, Jasper A Heinsbroek, Nobuya Koike, Erin B Larson, Evan A Balmuth, Brandon W Hughes, Rachel D Penrod, Jaswinder Kumar, Laura N Smith, Daniel Guzman, Joseph S Takahashi, Tae-Kyung Kim, Peter W Kalivas, David W Self, Yingxi Lin, Christopher W Cowa. HDAC5 and Its Target Gene, Npas4, Function in the Nucleus Accumbens to Regulate Cocaine-Conditioned Behaviors. Neuron. vol 96. issue 1. 2017-10-10. PMID:28957664. |
we found that dephosphorylated, nuclear histone deacetylase 5 (hdac5) in the nucleus accumbens (nac) reduced cocaine reward-context associations and relapse-like behaviors in a cocaine self-administration model. |
2017-10-10 |
2023-08-13 |
Not clear |
| Meaghan Creed, Niels R Ntamati, Ramesh Chandra, Mary Kay Lobo, Christian Lüsche. Convergence of Reinforcing and Anhedonic Cocaine Effects in the Ventral Pallidum. Neuron. vol 92. issue 1. 2017-10-03. PMID:27667004. |
cocaine-evoked synaptic plasticity in the reward system, particularly the nucleus accumbens (nac), drives drug-adaptive behavior. |
2017-10-03 |
2023-08-13 |
Not clear |
| Yadi Li, Haibo Dong, Feng Li, Gaoyan Wang, Wenhua Zhou, Rongbin Yu, Lingjun Zhan. Microstructures in striato-thalamo-orbitofrontal circuit in methamphetamine users. Acta radiologica (Stockholm, Sweden : 1987). vol 58. issue 11. 2017-10-03. PMID:28181466. |
freesurfer software was used for automated segmentation of the bilateral nucleus accumbens (nac), thalami, and orbitofrontal cortex (ofc). |
2017-10-03 |
2023-08-13 |
human |
| F Liu, S Laguesse, R Legastelois, N Morisot, S Ben Hamida, D Ro. mTORC1-dependent translation of collapsin response mediator protein-2 drives neuroadaptations underlying excessive alcohol-drinking behaviors. Molecular psychiatry. vol 22. issue 1. 2017-09-29. PMID:26952865. |
here, we report that excessive alcohol consumption increases the translation of downstream targets of mtorc1, including collapsin response mediator protein-2 (crmp-2), in the nucleus accumbens (nac) of rodents. |
2017-09-29 |
2023-08-13 |
Not clear |
| Joanna Peris, Kaley MacFadyen, Justin A Smith, Annette D de Kloet, Lei Wang, Eric G Kraus. Oxytocin receptors are expressed on dopamine and glutamate neurons in the mouse ventral tegmental area that project to nucleus accumbens and other mesolimbic targets. The Journal of comparative neurology. vol 525. issue 5. 2017-09-29. PMID:27615433. |
oxytocin (ot) has been implicated in mediating natural reward and ot-synthesizing neurons project to the ventral tegmental area (vta) and nucleus accumbens (nac); however, direct neuroanatomical evidence of ot regulation of da neurons within the vta is sparse. |
2017-09-29 |
2023-08-13 |
mouse |
| Jie Liang, Jia-Li Li, Ying Han, Yi-Xiao Luo, Yan-Xue Xue, Yàn Zhang, Yán Zhang, Li-Bo Zhang, Man-Li Chen, Lin Lu, Jie Sh. Calpain-GRIP Signaling in Nucleus Accumbens Core Mediates the Reconsolidation of Drug Reward Memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 37. 2017-09-29. PMID:28821652. |
in the present study, using a conditioned place preference (cpp) model, we found that exposure to drug-paired contextual stimuli induced the activation of calpain and decreased the expression of glutamate receptor interacting protein 1 (grip1) in the nucleus accumbens (nac) core, but not shell, of male rats. |
2017-09-29 |
2023-08-13 |
rat |
| Sergueï O Fetisso. [Hunger and satiety factors in the regulation of pleasure associated with feeding behavior]. Biologie aujourd'hui. vol 210. issue 4. 2017-09-28. PMID:28327283. |
the dopamine (da) system of the mesolimbic projections plays a key role in behavioral reward in general and is also involved in regulating feeding-associated pleasure in the forebrain including the nucleus accumbens (nac) and the lateral hypothalamic area (lha). |
2017-09-28 |
2023-08-13 |
Not clear |
| Julia Morud, Arghavan Ashouri, Erik Larsson, Mia Ericson, Bo Söderpal. Transcriptional profiling of the rat nucleus accumbens after modest or high alcohol exposure. PloS one. vol 12. issue 7. 2017-09-27. PMID:28715440. |
the present study utilizes whole-transcriptome sequencing (rna-seq) to investigate expression changes in the brain nucleus accumbens (nac), an area of particular interest in addictive disorders, of alcohol consuming rats. |
2017-09-27 |
2023-08-13 |
rat |
| Yuan-Hao Chen, Eagle Yi-Kung Huang, Tung-Tai Kuo, Barry J Hoffer, Jonathan Miller, Yu-Ching Chou, Yung-Hsiao Chian. Dopamine release in the nucleus accumbens is altered following traumatic brain injury. Neuroscience. vol 348. 2017-09-26. PMID:28196657. |
mild-to-severe traumatic brain injury (tbi) is frequently associated with prolonged dysfunction of reward circuitry, including motivation and salience, which suggests alterations of dopamine (da) processing within the core and shell of the nucleus accumbens (nac). |
2017-09-26 |
2023-08-13 |
Not clear |
| Gemma Huguet, Elisabet Kadar, Yasin Temel, Lee Wei Li. Electrical Stimulation Normalizes c-Fos Expression in the Deep Cerebellar Nuclei of Depressive-like Rats: Implication of Antidepressant Activity. Cerebellum (London, England). vol 16. issue 2. 2017-09-22. PMID:27435250. |
here, we investigated the stimulation effects of the ventromedial prefrontal cortex (vmpfc), nucleus accumbens (nac), and lateral habenular nucleus on the c-fos neuronal activity in various deep cerebellar and vestibular nuclei using the unpredictable chronic mild stress (cms) animal model of depression. |
2017-09-22 |
2023-08-13 |
rat |
| Tomokazu Tsurugizawa, Yoshifumi Abe, Denis Le Biha. Water apparent diffusion coefficient correlates with gamma oscillation of local field potentials in the rat brain nucleus accumbens following alcohol injection. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 37. issue 9. 2017-09-19. PMID:28058981. |
in the present study, we compared bold fmri signals, adc, and local field potentials (lfps) in the nucleus accumbens (nac) following injection of an ethanol solution (0.4 g/kg body weight) in rats under medetomidine anesthesia. |
2017-09-19 |
2023-08-13 |
rat |
| Ryan W Eaton, Tyler Libey, Eberhard E Fet. Operant conditioning of neural activity in freely behaving monkeys with intracranial reinforcement. Journal of neurophysiology. vol 117. issue 3. 2017-09-13. PMID:28031396. |
to reward cell activity in unconstrained primates, we sought sites in nucleus accumbens (nac) whose stimulation reinforced operant responding. |
2017-09-13 |
2023-08-13 |
monkey |
| Mona E Hervig, Morten S Thomsen, Imre Kalló, Jens D Mikkelse. Acute phencyclidine administration induces c-Fos-immunoreactivity in interneurons in cortical and subcortical regions. Neuroscience. vol 334. 2017-09-12. PMID:27476436. |
a single dose of pcp (10mg/kg, s.c.) significantly increased total number of c-fos-ir in: (1) the prelimbic, infralimbic, anterior cingulate, ventrolateral orbital, motor, somatosensory and retrosplenial cortices as well as the nucleus accumbens (nac), field ca1 of the hippocampus (ca1) field of hippocampus and mediodorsal thalamus (md); (2) pv-ir cells in the ventrolateral orbitofrontal and retrosplenial cortices and ca1 field of hippocampus; and (3) cb-ir cells in the motor cortex. |
2017-09-12 |
2023-08-13 |
rat |
| Candace R Lewis, Ryan M Bastle, Tawny B Manning, Sarah M Himes, Paulette Fennig, Phoebe R Conrad, Jenna Colwell, Broc A Pagni, Lyndsay A Hess, Caitlin G Matekel, Jason M Newbern, M Foster Oliv. Interactions between Early Life Stress, Nucleus Accumbens MeCP2 Expression, and Methamphetamine Self-Administration in Male Rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 12. 2017-09-11. PMID:27312406. |
in addition, we show new evidence that both els and methamphetamine sa alter the expression of the epigenetic regulator methyl cpg-binding protein 2 (mecp2) in key brain reward regions, particularly in the nucleus accumbens (nac) core. |
2017-09-11 |
2023-08-13 |
rat |
| Max F Oginsky, Paulette B Goforth, Cameron W Nobile, Luis F Lopez-Santiago, Carrie R Ferrari. Eating 'Junk-Food' Produces Rapid and Long-Lasting Increases in NAc CP-AMPA Receptors: Implications for Enhanced Cue-Induced Motivation and Food Addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 13. 2017-09-11. PMID:27383008. |
the nucleus accumbens (nac) mediates cue-triggered motivational responses, and activations in the nac triggered by food cues are stronger in people who are susceptible to obesity. |
2017-09-11 |
2023-08-13 |
rat |
| Liang Gong, Yingying Yin, Cancan He, Qing Ye, Feng Bai, Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang, Chunming Xie, Zhijun Zhan. Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. Journal of psychiatric research. vol 84. 2017-09-11. PMID:27673704. |
the bilateral nucleus accumbens (nac) were selected as seeds to construct reward circuits across all subjects. |
2017-09-11 |
2023-08-13 |
human |
| Hye Ran Park, In Hyang Kim, Hyejin Kang, Dong Soo Lee, Bung-Nyun Kim, Dong Gyu Kim, Sun Ha Pae. Nucleus accumbens deep brain stimulation for a patient with self-injurious behavior and autism spectrum disorder: functional and structural changes of the brain: report of a case and review of literature. Acta neurochirurgica. vol 159. issue 1. 2017-09-08. PMID:27807672. |
he was treated by bilateral nucleus accumbens (nac) dbs. |
2017-09-08 |
2023-08-13 |
Not clear |
| Zachary V Johnson, Hasse Walum, Yao Xiao, Paula C Riefkohl, Larry J Youn. Oxytocin receptors modulate a social salience neural network in male prairie voles. Hormones and behavior. vol 87. 2017-09-07. PMID:27793769. |
in voles, otr density in the nucleus accumbens (nac)-a region important for social and reward learning-is associated with individual and species variation in social attachment behavior. |
2017-09-07 |
2023-08-13 |
Not clear |
| Yongsheng Zhu, Bo Xing, Wei Dang, Yuanyuan Ji, Peng Yan, Yunxiao Li, Xiaomeng Qiao, Jianghua La. AUTS2 in the nucleus accumbens is essential for heroin-induced behavioral sensitization. Neuroscience. vol 333. 2017-09-06. PMID:27423627. |
here, we investigated the effects of acute and chronic heroin exposure on auts2 mrna and protein expression in the nucleus accumbens (nac) and caudate-putamen (cpu) to determine whether changes in auts2 expression are associated with heroin-induced locomotor sensitization in mice. |
2017-09-06 |
2023-08-13 |
mouse |