| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kayle S Sawyer, Marlene Oscar-Berman, Olivier J Barthelemy, George M Papadimitriou, Gordon J Harris, Nikos Makri. Gender dimorphism of brain reward system volumes in alcoholism. Psychiatry research. Neuroimaging. vol 263. 2017-12-13. PMID:28285206. |
we derived volumes of total brain, and cortical and subcortical reward-related structures including the dorsolateral prefrontal (dlpfc), orbitofrontal, and cingulate cortices, and the temporal pole, insula, amygdala, hippocampus, nucleus accumbens septi (nac), and ventral diencephalon (vdc). |
2017-12-13 |
2023-08-13 |
human |
| Caroline Jung, Ariana Rabinowitsch, Wei Ting Lee, Danielle Zheng, Soledad Cabeza de Vaca, Kenneth D Car. Effects of food restriction on expression of place conditioning and biochemical correlates in rat nucleus accumbens. Psychopharmacology. vol 233. issue 17. 2017-12-12. PMID:27376947. |
when ad libitum-fed rats undergo cocaine place preference conditioning (cpp) but are switched to food restriction for testing, cpp becomes resistant to extinction and correlates with phosphorylation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor glua1 at ser845 in nucleus accumbens (nac) core. |
2017-12-12 |
2023-08-13 |
rat |
| Takayo Sasagawa, Noriko Horii-Hayashi, Akinori Okuda, Takashi Hashimoto, Cho Azuma, Mayumi Nish. Long-term effects of maternal separation coupled with social isolation on reward seeking and changes in dopamine D1 receptor expression in the nucleus accumbens via DNA methylation in mice. Neuroscience letters. vol 641. 2017-12-12. PMID:28111354. |
we then focused on the mesolimbic dopamine pathway associated with reward-seeking behavior and measured both mrna and protein levels of tyrosine hydroxylase (th) in the ventral tegmental area (vta) and dopamine d1 and d2 receptors in the nucleus accumbens (nac). |
2017-12-12 |
2023-08-13 |
mouse |
| Alaa M Hammad, Fawaz Alasmari, Yusuf S Althobaiti, Youssef Sar. Modulatory effects of Ampicillin/Sulbactam on glial glutamate transporters and metabotropic glutamate receptor 1 as well as reinstatement to cocaine-seeking behavior. Behavioural brain research. vol 332. 2017-12-12. PMID:28624317. |
we also investigated the effects of amp/sul on the expression of glial glutamate transporters and metabotropic glutamate receptor 1 (mglur1) in the nucleus accumbens (nac) core and shell and the dorsomedial prefrontal cortex (dmpfc). |
2017-12-12 |
2023-08-13 |
rat |
| Abigail R Laman-Maharg, Tiffany Copeland, Evelyn Ordoñes Sanchez, Katharine L Campi, Brian C Traino. The long-term effects of stress and kappa opioid receptor activation on conditioned place aversion in male and female California mice. Behavioural brain research. vol 332. 2017-12-12. PMID:28625549. |
we also examined egr1 immunoreactivity, an indirect marker of neuronal activity, in the nucleus accumbens (nac) and found that stress and treatment with 10mg/kg of u50,488 increased egr1 immunoreactivity in the nac core in females but reduced activation in males. |
2017-12-12 |
2023-08-13 |
mouse |
| Caroline Menard, Madeline L Pfau, Georgia E Hodes, Veronika Kana, Victoria X Wang, Sylvain Bouchard, Aki Takahashi, Meghan E Flanigan, Hossein Aleyasin, Katherine B LeClair, William G Janssen, Benoit Labonté, Eric M Parise, Zachary S Lorsch, Sam A Golden, Mitra Heshmati, Carol Tamminga, Gustavo Turecki, Matthew Campbell, Zahi A Fayad, Cheuk Ying Tang, Miriam Merad, Scott J Russ. Social stress induces neurovascular pathology promoting depression. Nature neuroscience. vol 20. issue 12. 2017-12-12. PMID:29184215. |
we found reduced expression of the endothelial cell tight junction protein claudin-5 (cldn5) and abnormal blood vessel morphology in nucleus accumbens (nac) of stress-susceptible but not resilient mice. |
2017-12-12 |
2023-08-13 |
mouse |
| Sa-Ik Hong, Thi-Lien Nguyen, Shi-Xun Ma, Hyoung-Chun Kim, Seok-Yong Lee, Choon-Gon Jan. TRPV1 modulates morphine-induced conditioned place preference via p38 MAPK in the nucleus accumbens. Behavioural brain research. vol 334. 2017-12-11. PMID:28734766. |
however, the role of trpv1 on morphine-conditioned reward in addiction-related brain regions, such as the nucleus accumbens (nac), has not been previously established. |
2017-12-11 |
2023-08-13 |
mouse |
| M Shen, C Jiang, P Liu, F Wang, L M. Mesolimbic leptin signaling negatively regulates cocaine-conditioned reward. Translational psychiatry. vol 6. issue 12. 2017-12-07. PMID:27922639. |
our results showed that inhibition of leptin signaling by intracerebroventricular infusion of the leptin receptor (lepr) antagonist smla during cocaine conditioning increased the cocaine-cpp and upregulated the level of dopamine and its metabolites in the nucleus accumbens (nac). |
2017-12-07 |
2023-08-13 |
Not clear |
| Chengji Piao, Xiaofei Deng, Xingyue Wang, Yiran Yuan, Zhengkui Liu, Jing Lian. Altered function in medial prefrontal cortex and nucleus accumbens links to stress-induced behavioral inflexibility. Behavioural brain research. vol 317. 2017-12-05. PMID:27616342. |
the medial prefrontal cortex (mpfc) and its output area, the nucleus accumbens (nac), are implicated in mediating attentional set-shifting. |
2017-12-05 |
2023-08-13 |
rat |
| Kendra L Kobrin, Danielle T Arena, Stephen C Heinrichs, Olivia H Nguyen, Gary B Kapla. Dopamine D1 receptor agonist treatment attenuates extinction of morphine conditioned place preference while increasing dendritic complexity in the nucleus accumbens core. Behavioural brain research. vol 322. issue Pt A. 2017-12-01. PMID:28089852. |
we examined the effect of d1r agonist skf81297 on the extinction of opioid cpp and associated dendritic morphology in the nucleus accumbens (nac), a region involved with reward integration and its extinction. |
2017-12-01 |
2023-08-13 |
mouse |
| Omar Ouachikh, Carine Chassain, Guilhem Pagès, Franck Durif, Aziz Hafid. mGlu5 receptor antagonist blocks bromocriptine-induced conditioned place preference in bilateral mesolimbic-lesioned rat. Behavioural brain research. vol 317. 2017-11-29. PMID:27638036. |
the drt reinforcement effect is due to its action on the reward system, particularly on the nucleus accumbens (nac). |
2017-11-29 |
2023-08-13 |
rat |
| Stephanie K Nygard, Anthony Klambatsen, Bailey Balouch, Vanya Quinones-Jenab, Shirzad Jena. NMDAR dependent intracellular responses associated with cocaine conditioned place preference behavior. Behavioural brain research. vol 317. 2017-11-29. PMID:27664298. |
n-methyl-d-aspartate receptor (nmdar) antagonism prior to cocaine administration during conditioning blocked the acquisition of cocaine cpp and reduced nucleus accumbens (nac) phosphorylated-erk (perk) and phosphorylated creb (pcreb) levels following the cpp test (drug-free). |
2017-11-29 |
2023-08-13 |
Not clear |
| Caitlin A Orsini, Marci R Mitchell, Sara C Heshmati, Kristy G Shimp, Megan S Spurrell, Jennifer L Bizon, Barry Setlo. Effects of nucleus accumbens amphetamine administration on performance in a delay discounting task. Behavioural brain research. vol 321. 2017-11-29. PMID:28057530. |
chronic cocaine can also result in enhanced dopamine (da) release in the nucleus accumbens (nac) in response to reward-related cues. |
2017-11-29 |
2023-08-13 |
rat |
| Shanna L Resendez, Piper C Keyes, Jeremy J Day, Caely Hambro, Curtis J Austin, Francis K Maina, Lori N Eidson, Kirsten A Porter-Stransky, Natalie Nevárez, J William McLean, Morgan A Kuhnmuench, Anne Z Murphy, Tiffany A Mathews, Brandon J Aragon. Dopamine and opioid systems interact within the nucleus accumbens to maintain monogamous pair bonds. eLife. vol 5. 2017-11-28. PMID:27371827. |
for both sexes, we show that pair bonding up-regulates mrna expression for genes encoding d1-like dopamine (da) receptors and dynorphin as well as enhances stimulated da release within the nucleus accumbens (nac). |
2017-11-28 |
2023-08-13 |
Not clear |
| Giannina Descalzi, Vasiliki Mitsi, Immanuel Purushothaman, Sevasti Gaspari, Kleopatra Avrampou, Yong-Hwee Eddie Loh, Li Shen, Venetia Zachario. Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression. Science signaling. vol 10. issue 471. 2017-11-28. PMID:28325815. |
using two mouse models of neuropathic pain and depression [spared nerve injury (sni) and chronic unpredictable stress (cus)], we performed next-generation rna sequencing and pathway analysis to monitor changes in gene expression in the nucleus accumbens (nac), the medial prefrontal cortex (mpfc), and the periaqueductal gray (pag). |
2017-11-28 |
2023-08-13 |
mouse |
| Jung Hoon Shin, Martin F Adrover, Veronica A Alvare. Distinctive Modulation of Dopamine Release in the Nucleus Accumbens Shell Mediated by Dopamine and Acetylcholine Receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 46. 2017-11-28. PMID:29030431. |
nucleus accumbens (nac) shell shows unique dopamine (da) signals |
2017-11-28 |
2023-08-13 |
Not clear |
| Laura N De Giovanni, Andrea S Guzman, Miriam B Virgolini, Liliana M Cancel. NMDA antagonist MK 801 in nucleus accumbens core but not shell disrupts the restraint stress-induced reinstatement of extinguished cocaine-conditioned place preference in rats. Behavioural brain research. vol 315. 2017-11-24. PMID:27506656. |
the aim of this study was to investigate the contribution of nmda receptors within core vs. shell nucleus accumbens (nac) subregions to restraint stress-induced reinstatement of extinguished cocaine-cpp. |
2017-11-24 |
2023-08-13 |
rat |
| Luyi Zhou, Wei-Lun Sun, Karen Weierstall, Ana Christina Minerly, Jan Weiner, Shirzad Jenab, Vanya Quinones-Jena. Sex differences in behavioral and PKA cascade responses to repeated cocaine administration. Psychopharmacology. vol 233. issue 19-20. 2017-11-24. PMID:27553823. |
correspondent pka-associated signaling in the nucleus accumbens (nac) and caudate-putamen (cpu) was measured at each time point. |
2017-11-24 |
2023-08-13 |
rat |
| Lydia N Baxter-Potter, Angela M Henricks, Anthony L Berger, Kennedy V Bieniasz, Janelle M Lugo, Ryan J McLaughli. Alcohol vapor exposure differentially impacts mesocorticolimbic cytokine expression in a sex-, region-, and duration-specific manner. Neuroscience. vol 346. 2017-11-20. PMID:28131626. |
results indicated that acute alcohol exposure increased tnfα mrna expression in the basolateral amygdala (bla), nucleus accumbens (nac), and ventral tegmental area (vta), whereas il-6 expression was increased in the vta, nac, and ventromedial prefrontal cortex (vmpfc) only in males. |
2017-11-20 |
2023-08-13 |
rat |
| Y Kim, S McGee, J K Czeczor, A J Walker, R P Kale, A Z Kouzani, K Walder, M Berk, S J Ty. Nucleus accumbens deep-brain stimulation efficacy in ACTH-pretreated rats: alterations in mitochondrial function relate to antidepressant-like effects. Translational psychiatry. vol 6. issue 6. 2017-11-17. PMID:27327257. |
second, we examined the mood-regulatory actions of chronic (7 day) high-frequency nucleus accumbens (nac) deep-brain stimulation (dbs; 130 hz, 100 μa, 90 μs) and concomitant pfc mitochondrial function. |
2017-11-17 |
2023-08-13 |
rat |