| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zheng-Xiong Xi, Jeremy G Gilbert, Xiao-Qing Peng, Arlene C Pak, Xia Li, Eliot L Gardne. Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 33. 2006-09-12. PMID:16914679. |
given the importance of dopamine, glutamate, and gaba in cocaine reward and relapse, we studied the effects of am251 [n-(piperidin-1-yl)-5-(4-iodophonyl)-1-(2,4-dichlorophenyl)-4-methyl-1h-pyrazole-3-carboxamide], a novel highly selective cb1 receptor antagonist, on cocaine-primed reinstatement of drug-seeking behavior and on cocaine-induced changes in extracellular da, glutamate, and gaba in the nucleus accumbens (nac) under reinstatement conditions. |
2006-09-12 |
2023-08-12 |
rat |
| Eric J Nestler, William A Carlezo. The mesolimbic dopamine reward circuit in depression. Biological psychiatry. vol 59. issue 12. 2006-09-07. PMID:16566899. |
here we focus on the potential role of the nucleus accumbens (nac; ventral striatum) and its dopaminergic input from the ventral tegmental area (vta), which form the mesolimbic dopamine system, in depression. |
2006-09-07 |
2023-08-12 |
Not clear |
| Kaushik Misra, Subhash C Pande. The decreased cyclic-AMP dependent-protein kinase A function in the nucleus accumbens: a role in alcohol drinking but not in anxiety-like behaviors in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 7. 2006-09-05. PMID:16192983. |
the nucleus accumbens (nac) brain structures have been implicated in the reward and reinforcing properties of ethanol. |
2006-09-05 |
2023-08-12 |
rat |
| Zhen Li, Lin Gao, Qiang Liu, Cong Cao, Xiu Lan Sun, Jian Hua Ding, Gang H. Aquaporin-4 knockout regulated cocaine-induced behavior and neurochemical changes in mice. Neuroscience letters. vol 403. issue 3. 2006-09-01. PMID:16797122. |
the results reveal that aqp4 deletion attenuated locomotor activity in acute and repeated cocaine exposure mice, and induced a decrease of extracellular dopamine and glutamate levels in the nucleus accumbens (nac), a brain region known to be critically involved in the addictive properties of cocaine. |
2006-09-01 |
2023-08-12 |
mouse |
| Sara R Jones, Tiffany A Mathews, Evgeny A Budygi. Effect of moderate ethanol dose on dopamine uptake in rat nucleus accumbens in vivo. Synapse (New York, N.Y.). vol 60. issue 3. 2006-08-28. PMID:16752364. |
the present study was designed to evaluate the effects of a moderate dose of ethanol (1 g/kg) on dopamine (da) dynamics in rat nucleus accumbens (nac) using fast-scan cyclic voltammetry. |
2006-08-28 |
2023-08-12 |
rat |
| Samuel B Kombian, Kethireddy V V Ananthalakshmi, Subramanian S Parvathy, Wandikayi C Matow. Cholecystokinin-2 receptors couple to cAMP-protein kinase A to depress excitatory synaptic currents in rat nucleus accumbens in vitro. Canadian journal of physiology and pharmacology. vol 84. issue 2. 2006-08-25. PMID:16900946. |
we recently reported that the activation of cholecystokinin-2 receptors depress evoked excitatory postsynaptic currents (epscs) in nucleus accumbens (nac) indirectly through gamma-aminobutyric acid (gaba) acting on gamma-aminobutyric acid-b (gaba(b)) receptors. |
2006-08-25 |
2023-08-12 |
rat |
| Birgit Abler, Henrik Walter, Susanne Erk, Hannes Kammerer, Manfred Spitze. Prediction error as a linear function of reward probability is coded in human nucleus accumbens. NeuroImage. vol 31. issue 2. 2006-08-14. PMID:16487726. |
first, during the expectation period of the task, the fmri signal in the human nucleus accumbens (nac) increased linearly with the probability of the reward. |
2006-08-14 |
2023-08-12 |
human |
| Qiang Liu, Zhen Li, Jian-Hua Ding, Su-Yi Liu, Jie Wu, Gang H. Iptakalim inhibits nicotine-induced enhancement of extracellular dopamine and glutamate levels in the nucleus accumbens of rats. Brain research. vol 1085. issue 1. 2006-08-10. PMID:16647046. |
in the present study, we examined whether ipt prevents nicotine-induced neurotransmitter release in the nucleus accumbens (nac) using in vivo microdialysis methods in awake, freely moving rats. |
2006-08-10 |
2023-08-12 |
rat |
| Todor V Gerdjikov, Richard J Beninge. Place preference induced by nucleus accumbens amphetamine is impaired by local blockade of Group II metabotropic glutamate receptors in rats. BMC neuroscience. vol 7. 2006-08-09. PMID:16734896. |
the nucleus accumbens (nac) plays a critical role in amphetamine-produced conditioned place preference (cpp). |
2006-08-09 |
2023-08-12 |
rat |
| Jingyi Ma, L Stan Leun. Limbic system participates in mediating the effects of general anesthetics. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 6. 2006-08-07. PMID:16205783. |
in freely behaving rats, muscimol (0.25 microg) or saline was infused intracerebrally into one of four areas-the supramammillary area (sum), nucleus accumbens (nac), ventral pallidum (vp), and ventral tegmental area (vta)-and righting, pain, and eeg responses were recorded following either halothane or sodium pentobarbital, representing inhalational and injectable general anesthetic, respectively. |
2006-08-07 |
2023-08-12 |
rat |
| Lina Yao, Krista McFarland, Peidong Fan, Zhan Jiang, Takashi Ueda, Ivan Diamon. Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 20. 2006-07-28. PMID:16684876. |
opiate and cb1 receptors are coexpressed in the nucleus accumbens (nac) and dorsal striatum. |
2006-07-28 |
2023-08-12 |
human |
| Amani Eltayb, Marie-Louise G Wadenberg, Björn Schilström, Torgny H Svensso. Topiramate augments the antipsychotic-like effect and cortical dopamine output of raclopride. Naunyn-Schmiedeberg's archives of pharmacology. vol 372. issue 3. 2006-07-20. PMID:16284783. |
we also examined the effect of this drug treatment on da release in the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), using in vivo microdialysis in freely moving animals. |
2006-07-20 |
2023-08-12 |
rat |
| Nina Lindblom, Sabina H L de Villiers, Svetlana Semenova, Genadiy Kalayanov, Sandra Gordon, Björn Schilström, Anette M Johansson, Athina Markou, Torgny H Svensso. Active immunisation against nicotine blocks the reward facilitating effects of nicotine and partially prevents nicotine withdrawal in the rat as measured by dopamine output in the nucleus accumbens, brain reward thresholds and somatic signs. Naunyn-Schmiedeberg's archives of pharmacology. vol 372. issue 3. 2006-07-20. PMID:16292514. |
we recently showed that active immunisation with the nicotine immunoconjugate ip18-klh reduces the nicotine-induced increase in dopamine (da) output in the nucleus accumbens (nac) and prevents reinstatement of nicotine-seeking behaviour in rats. |
2006-07-20 |
2023-08-12 |
rat |
| Gilad Gal, Daniela Schiller, Ina Weine. Latent inhibition is disrupted by nucleus accumbens shell lesion but is abnormally persistent following entire nucleus accumbens lesion: The neural site controlling the expression and disruption of the stimulus preexposure effect. Behavioural brain research. vol 162. issue 2. 2006-07-19. PMID:15970218. |
the present experiments investigated the role of the nucleus accumbens (nac) in li. |
2006-07-19 |
2023-08-12 |
rat |
| Xiang Yang Zhang, Priscilla Kehoe, Therese A Koste. Neonatal isolation alters estrous cycle effects on ventral striatal extracellular monoamine levels. Progress in neuro-psychopharmacology & biological psychiatry. vol 30. issue 3. 2006-07-19. PMID:16412549. |
now, we examine basal 5-ht, da, and norepinephrine (ne) levels in nucleus accumbens (nac) using in vivo microdialysis in adult male and female rats with or without iso experience. |
2006-07-19 |
2023-08-12 |
rat |
| Pamela B Yang, Alan C Swann, Nachum Dafn. Sensory-evoked potentials recordings from the ventral tegmental area, nucleus accumbens, prefrontal cortex, and caudate nucleus and locomotor activity are modulated in dose-response characteristics by methylphenidate. Brain research. vol 1073-1074. 2006-07-19. PMID:16473326. |
for the electrophysiological experiments, animals were implanted with permanent electrodes in the ventral tegmental area (vta), nucleus accumbens (nac), prefrontal cortex (pfc), and caudate nucleus (cn) under general anesthesia. |
2006-07-19 |
2023-08-12 |
rat |
| A Pisanu, E Acquas, S Fenu, G Di Chiar. Modulation of Delta(9)-THC-induced increase of cortical and hippocampal acetylcholine release by micro opioid and D(1) dopamine receptors. Neuropharmacology. vol 50. issue 6. 2006-07-13. PMID:16427098. |
since delta(9)-thc has been shown to increase da release in the nucleus accumbens (nac) shell via a micro(1)-opioid receptor mediated mechanism located in the vta (tanda, g., pontieri, f.e., di chiara, g., 1997. |
2006-07-13 |
2023-08-12 |
rat |
| Elena H Chartoff, Stephen D Mague, Matthew F Barhight, Andrew M Smith, William A Carlezo. Behavioral and molecular effects of dopamine D1 receptor stimulation during naloxone-precipitated morphine withdrawal. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 24. 2006-07-11. PMID:16775132. |
the nucleus accumbens (nac) receives extensive dopaminergic input and is an important substrate for mediating these aversive states. |
2006-07-11 |
2023-08-12 |
rat |
| Hiroko Okutsu, Shu Watanabe, Ichiro Takahashi, Yuri Aono, Tadashi Saigusa, Noriaki Koshikawa, Alexander R Cool. Endomorphin-2 and endomorphin-1 promote the extracellular amount of accumbal dopamine via nonopioid and mu-opioid receptors, respectively. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 2. 2006-07-06. PMID:16034447. |
activation of mu-opioid receptors in the nucleus accumbens (nac) is known to increase accumbal dopamine efflux in rats. |
2006-07-06 |
2023-08-12 |
rat |
| Pei Fei Gu, Chun Fu Wu, Jing Yu Yang, Yu Shang, Yue Hou, Xiu Li Bi, Fang Da. Differential effects of drug-induced ascorbic acid release in the striatum and nucleus accumbens of freely moving rats. Neuroscience letters. vol 399. issue 1-2. 2006-06-30. PMID:16480820. |
previous studies have shown that striatum and nucleus accumbens (nac) are two different structures in mediating addictive drug-induced ascorbic acid (aa) release. |
2006-06-30 |
2023-08-12 |
rat |