Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Todor V Gerdjikov, Andrew C Giles, Shelley N Swain, Richard J Beninge. Nucleus accumbens PKA inhibition blocks acquisition but enhances expression of amphetamine-produced conditioned activity in rats. Psychopharmacology. vol 190. issue 1. 2007-04-03. PMID:17047929. |
the nucleus accumbens (nac) plays a central role in dopamine-produced reward-related learning. |
2007-04-03 |
2023-08-12 |
rat |
Amy Zmarowski, Martin Sarter, John P Brun. Glutamate receptors in nucleus accumbens mediate regionally selective increases in cortical acetylcholine release. Synapse (New York, N.Y.). vol 61. issue 3. 2007-03-27. PMID:17146770. |
bfcs activity is regulated by several cortical and subcortical structures, including the nucleus accumbens (nac) and prefrontal cortex (pfc). |
2007-03-27 |
2023-08-12 |
Not clear |
Eugenia Shekhtman, Joel C Geerling, Arthur D Loew. Aldosterone-sensitive neurons of the nucleus of the solitary tract: multisynaptic pathway to the nucleus accumbens. The Journal of comparative neurology. vol 501. issue 2. 2007-03-27. PMID:17226797. |
the nucleus accumbens (nac) is part of a forebrain system implicated in reward, motivation, and learning. |
2007-03-27 |
2023-08-12 |
rat |
Evan P Sleipness, Barbara A Sorg, Heiko T Janse. Diurnal differences in dopamine transporter and tyrosine hydroxylase levels in rat brain: dependence on the suprachiasmatic nucleus. Brain research. vol 1129. issue 1. 2007-03-22. PMID:17156761. |
we used western blots to measure expression of dopamine transporter (dat) and tyrosine hydroxylase (th) proteins in the medial prefrontal cortex (mpfc), nucleus accumbens (nac), and caudate in sham and scn-lesioned (scnx) rats at zt4 (zeitgeber time 4, 4 h after lights-on) or zt20 (8 h after lights-off). |
2007-03-22 |
2023-08-12 |
rat |
Marcello D'Ascenzo, Tommaso Fellin, Miho Terunuma, Raquel Revilla-Sanchez, David F Meaney, Yves P Auberson, Stephen J Moss, Philip G Haydo. mGluR5 stimulates gliotransmission in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 6. 2007-03-22. PMID:17259307. |
although metabotropic glutamate receptor 5 (mglur5) is essential for cocaine self-administration and drug-seeking behavior, there is limited knowledge of the cellular actions of this receptor in the nucleus accumbens (nac). |
2007-03-22 |
2023-08-12 |
Not clear |
Yao-Ying Ma, Ning-Ning Chu, Chang-Yong Guo, Ji-Sheng Han, Cai-Lian Cu. NR2B-containing NMDA receptor is required for morphine-but not stress-induced reinstatement. Experimental neurology. vol 203. issue 2. 2007-03-20. PMID:17014848. |
parallel with this, protein levels of the nmda receptor 2b subunit (nr2b) were elevated in the nucleus accumbens (nac) and the hippocampus, but not the prefrontal cortex, of reinstated rats. |
2007-03-20 |
2023-08-12 |
rat |
Marie-Astrid Pezze, Jeffrey W Dalley, Trevor W Robbin. Differential roles of dopamine D1 and D2 receptors in the nucleus accumbens in attentional performance on the five-choice serial reaction time task. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 2. 2007-03-02. PMID:16641946. |
nucleus accumbens (nac) dopamine may play a role in attentional and executive processes, as it modulates cortico-limbic inputs, including afferents from the prefrontal cortex. |
2007-03-02 |
2023-08-12 |
rat |
N Tannu, D C Mash, S E Hemb. Cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims. Molecular psychiatry. vol 12. issue 1. 2007-02-27. PMID:17075605. |
chronic cocaine use in humans and animal models is known to lead to pronounced alterations in neuronal function in the nucleus accumbens (nac), a brain region associated with drug reinforcement. |
2007-02-27 |
2023-08-12 |
human |
Sanjeev K Bhardwaj, Clifford M Cassidy, Lalit K Srivastav. Changes in syntaxin-1B mRNA in the nucleus accumbens of amphetamine-sensitized rats. The international journal of neuropsychopharmacology. vol 9. issue 6. 2007-02-26. PMID:16359582. |
we have previously reported changes in the content of axonal plasma membrane protein syntaxin-1 in the nucleus accumbens (nac) of amphetamine-sensitized rats. |
2007-02-26 |
2023-08-12 |
rat |
Xing-Long Gu, Long-Chuan Y. Involvement of opioid receptors in oxytocin-induced antinociception in the nucleus accumbens of rats. The journal of pain. vol 8. issue 1. 2007-02-26. PMID:17097925. |
it has been shown that oxytocin receptors and fibers with oxytocin were distributed in the nucleus accumbens (nac) of rats. |
2007-02-26 |
2023-08-12 |
mouse |
Kevin D Lominac, Zuzana Kapasova, Reem A Hannun, Cole Patterson, Lawrence D Middaugh, Karen K Szumlinsk. Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties. Drug and alcohol dependence. vol 85. issue 2. 2007-02-22. PMID:16697125. |
mpep pretreatment did not significantly alter the etoh dose-locomotor response function; however, it prevented etoh-induced changes in extracellular dopamine, glutamate and gaba in the nucleus accumbens (nac). |
2007-02-22 |
2023-08-12 |
mouse |
Fang Dai, Jing Yu Yang, Pei Fei Gu, Yue Hou, Chun Fu W. Effect of drug-induced ascorbic acid release in the striatum and the nucleus accumbens in hippocampus-lesioned rats. Brain research. vol 1125. issue 1. 2007-02-20. PMID:17112479. |
the mechanism of ethanol, morphine, methamphetamine (map), and nicotine-induced ascorbic acid (aa) release in striatum, and nucleus accumbens (nac) is not well understood. |
2007-02-20 |
2023-08-12 |
rat |
Yan Pan, Yemiliya Berman, Sandra Haberny, Emanuel Meller, Kenneth D Car. Synthesis, protein levels, activity, and phosphorylation state of tyrosine hydroxylase in mesoaccumbens and nigrostriatal dopamine pathways of chronically food-restricted rats. Brain research. vol 1122. issue 1. 2007-01-30. PMID:17010321. |
chronic food restriction (fr) enhances the rewarding and motor-activating effects of abused drugs, and is accompanied by changes in dopamine (da) dynamics and increased d-1 da receptor-mediated cell signaling and transcriptional responses in nucleus accumbens (nac). |
2007-01-30 |
2023-08-12 |
rat |
Samuel B Kombian, Kethireddy V V Ananthalakshmi, Ivan O Edafiogh. Enaminones and norepinephrine employ convergent mechanisms to depress excitatory synaptic transmission in the rat nucleus accumbens in vitro. The European journal of neuroscience. vol 24. issue 10. 2007-01-30. PMID:17156204. |
we recently reported that anticonvulsant anilino enaminones depress excitatory postsynaptic currents (epscs) in the nucleus accumbens (nac) indirectly via gamma-aminobutyric acid (gaba) acting on gaba(b) receptors [s.b. |
2007-01-30 |
2023-08-12 |
rat |
Mark Jeremy Hunt, Beryl Raynaud, Rene Garci. Ketamine dose-dependently induces high-frequency oscillations in the nucleus accumbens in freely moving rats. Biological psychiatry. vol 60. issue 11. 2007-01-26. PMID:16650831. |
increasing evidence has implicated aberrant activity in the nucleus accumbens (nac) with the pathophysiology of schizophrenia. |
2007-01-26 |
2023-08-12 |
rat |
Maria G Corda, Giovanna Piras, Osvaldo Giorg. Neonatal ventral hippocampal lesions potentiate amphetamine-induced increments in dopamine efflux in the core, but not the shell, of the nucleus accumbens. Biological psychiatry. vol 60. issue 11. 2007-01-26. PMID:16934777. |
the precise nature of presynaptic aspects of accumbal dopamine (da) function in these alterations is however uncertain: previous studies have found that the exacerbated responses to amph of nvhl rats are associated with either decreased or unchanged da efflux in the nucleus accumbens (nac) as compared with shams. |
2007-01-26 |
2023-08-12 |
rat |
Yan Zhou, Johannes Adomako-Mensah, Vadim Yuferov, Ann Ho, Jianhua Zhang, Ming Xu, Mary Jeanne Kree. Effects of acute "binge" cocaine on mRNA levels of mu opioid receptor and neuropeptides in dopamine D1 or D3 receptor knockout mice. Synapse (New York, N.Y.). vol 61. issue 1. 2007-01-26. PMID:17068774. |
in the present studies, we found an increase in basal mop-r mrna levels in the fc of both d1-/- and d3-/- mice compared to wild type controls, with no change in the nucleus accumbens (nac) core or caudate-putamen (cpu). |
2007-01-26 |
2023-08-12 |
mouse |
Daria Peleg-Raibstein, Joram Feldo. Effects of dorsal and ventral hippocampal NMDA stimulation on nucleus accumbens core and shell dopamine release. Neuropharmacology. vol 51. issue 5. 2007-01-12. PMID:16876207. |
this study has analysed the effects of infusing n-methyl-d-aspartate (nmda) into either the ventral or dorsal hippocampus on dopamine (da) transmission in the nucleus accumbens (nac) core or shell for the first time. |
2007-01-12 |
2023-08-12 |
Not clear |
Jianhua Zhang, Ming X. Opposite regulation of cocaine-induced intracellular signaling and gene expression by dopamine D1 and D3 receptors. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105899. |
both dopamine d1 and d3 receptors mediate cocaine-induced behaviors and they are also coexpressed in the same neurons in the nucleus accumbens (nac) and caudoputamen (cpu). |
2007-01-10 |
2023-08-12 |
Not clear |
Jose A Crespo, Leigh V Panlilio, Charles W Schindler, Katja Sturm, Alois Saria, Gerald Zerni. Peri-response pharmacokinetics of remifentanil during a self-administration session indicates that neither blood nor brain levels are titrated. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105948. |
our peri-response analysis did not detect any "threshold" rmf level, either in blood or in the nucleus accumbens (nac) core as a deep brain region that might determine a rat's "decision" to re-emit a response during a multiple-injection drug self-administration session. |
2007-01-10 |
2023-08-12 |
rat |