| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M V Podda, E Riccardi, M D'Ascenzo, G B Azzena, C Grass. Dopamine D1-like receptor activation depolarizes medium spiny neurons of the mouse nucleus accumbens by inhibiting inwardly rectifying K+ currents through a cAMP-dependent protein kinase A-independent mechanism. Neuroscience. vol 167. issue 3. 2010-06-29. PMID:20211700. |
it also modulates the plasticity and firing properties of medium spiny neurons (msns) in the nucleus accumbens (nac), although the effects of camp signaling on the resting membrane potential (rmp) of msns has not been specifically defined. |
2010-06-29 |
2023-08-12 |
mouse |
| Sarvin Ghods-Sharifi, Stan B Floresc. Differential effects on effort discounting induced by inactivations of the nucleus accumbens core or shell. Behavioral neuroscience. vol 124. issue 2. 2010-06-24. PMID:20364878. |
the authors investigated the contribution of the nucleus accumbens (nac) core and shell to effort-based decision making using a discounting procedure. |
2010-06-24 |
2023-08-12 |
rat |
| b' Sanna Kurling-Kailanto, Aino Kankaanp\\xc3\\xa4\\xc3\\xa4, Timo Sepp\\xc3\\xa4l\\xc3\\xa. Subchronic nandrolone administration reduces cocaine-induced dopamine and 5-hydroxytryptamine outflow in the rat nucleus accumbens. Psychopharmacology. vol 209. issue 3. 2010-06-22. PMID:20186395.' |
we have previously shown that pretreatment with nandrolone decanoate attenuates dose-dependently the increase in extracellular dopamine (da) concentration evoked by amphetamine and 3,4-methylenedioyxymethamphetamine in the nucleus accumbens (nac). |
2010-06-22 |
2023-08-12 |
rat |
| Tie-feng Shi, Chun-xiao Yang, Dong-xiao Yang, Run-sheng Jiao, Guang-wen Zhang, He-ren Gao, Duo Zhang, Man-ying X. MK-801 changes the role of glutamic acid on modulation of algesia in nucleus accumbens. Biochemical and biophysical research communications. vol 395. issue 3. 2010-06-21. PMID:20382122. |
this study examines the effect of mk-801, glu on the pain-evoked response of pain-excitation neurons (pens) and pain-inhibition neurons (pins) in the nucleus accumbens (nac) of rats. |
2010-06-21 |
2023-08-12 |
rat |
| Joshua L Jones, Jeremy J Day, Brandon J Aragona, Robert A Wheeler, R Mark Wightman, Regina M Carell. Basolateral amygdala modulates terminal dopamine release in the nucleus accumbens and conditioned responding. Biological psychiatry. vol 67. issue 8. 2010-06-17. PMID:20044074. |
dopamine signaling in the nucleus accumbens (nac) is essential for goal-directed behaviors and primarily arises from burst firing of ventral tegmental area neurons. |
2010-06-17 |
2023-08-12 |
Not clear |
| M Grilli, F Lagomarsino, S Zappettini, S Preda, E Mura, S Govoni, M March. Specific inhibitory effect of amyloid-beta on presynaptic muscarinic receptor subtypes modulating neurotransmitter release in the rat nucleus accumbens. Neuroscience. vol 167. issue 2. 2010-06-17. PMID:20144691. |
in this study we investigate on the effect of amyloid-beta1-40 (a beta 1-40) on the oxotremorine (oxo)-induced release of [(3)h] dopamine (da), [(3)h]gaba and [(3)h]acetylcholine (ach) from synaptosomes in the rat nucleus accumbens (nac). |
2010-06-17 |
2023-08-12 |
rat |
| Yukihiko Shirayama, Shigeyuki Chak. Neurochemistry of the nucleus accumbens and its relevance to depression and antidepressant action in rodents. Current neuropharmacology. vol 4. issue 4. 2010-06-10. PMID:18654637. |
there is accumulating evidence that the nucleus accumbens (nac) plays an important role in the pathophysiology of depression. |
2010-06-10 |
2023-08-12 |
Not clear |
| Xiongzhao Zhu, Ting Li, Sufang Peng, Xiuling Ma, Xiaogang Chen, Xiuwu Zhan. Maternal deprivation-caused behavioral abnormalities in adult rats relate to a non-methylation-regulated D2 receptor levels in the nucleus accumbens. Behavioural brain research. vol 209. issue 2. 2010-06-02. PMID:20144661. |
in this study we investigated the effects of maternal deprivation on adult rats' spatial learning and memory, exploratory, and limbic activity and their correlations with the gene expression of dopamine transporter (dat) and dopamine d1, d2, d3 receptors (drd1, drd2, drd3) in the nucleus accumbens (nac). |
2010-06-02 |
2023-08-12 |
rat |
| Sonia Y Bernal, Khalid Touzani, Meri Gerges, Yana Abayev, Anthony Sclafani, Richard J Bodna. Opioid receptor antagonism in the nucleus accumbens fails to block the expression of sugar-conditioned flavor preferences in rats. Pharmacology, biochemistry, and behavior. vol 95. issue 1. 2010-06-01. PMID:20006967. |
because opioid signaling in the nucleus accumbens (nac) is implicated in food reward, this study determined if ntx administered into the nac would block the expression of sugar-conditioned preferences. |
2010-06-01 |
2023-08-12 |
rat |
| Paul M Forlano, Catherine S Woolle. Quantitative analysis of pre- and postsynaptic sex differences in the nucleus accumbens. The Journal of comparative neurology. vol 518. issue 8. 2010-06-01. PMID:20151363. |
the nucleus accumbens (nac) plays a central role in motivation and reward. |
2010-06-01 |
2023-08-12 |
rat |
| Jingyi Ma, Richard Boyce, L Stan Leun. Nucleus accumbens mu opioid receptors mediate immediate postictal decrease in locomotion after an amygdaloid kindled seizure in rats. Epilepsy & behavior : E&B. vol 17. issue 2. 2010-05-21. PMID:20116338. |
we investigated the involvement of opioid receptors in the nucleus accumbens (nac) in amygdaloid kindling-induced postictal decrease in locomotion (pdl) in rats. |
2010-05-21 |
2023-08-12 |
rat |
| Qiang Chen, Xiongzhao Zhu, Yu Zhang, William C Wetsel, Tong H Lee, Xiuwu Zhan. Integrin-linked kinase is involved in cocaine sensitization by regulating PSD-95 and synapsin I expression and GluR1 Ser845 phosphorylation. Journal of molecular neuroscience : MN. vol 40. issue 3. 2010-05-07. PMID:19629758. |
our recent studies have demonstrated that integrin-linked kinase (ilk) is involved in the induction and maintenance of cocaine behavioral sensitization and chronic cocaine-induced neural plasticity in the nucleus accumbens (nac) core. |
2010-05-07 |
2023-08-12 |
rat |
| Kenneth Blum, Thomas J H Chen, Amanda L H Chen, Margaret Madigan, B William Downs, Roger L Waite, Eric R Braverman, Mallory Kerner, Abdalla Bowirrat, John Giordano, Harry Henshaw, Mark S Gol. Do dopaminergic gene polymorphisms affect mesolimbic reward activation of music listening response? Therapeutic impact on Reward Deficiency Syndrome (RDS). Medical hypotheses. vol 74. issue 3. 2010-05-07. PMID:19914781. |
using fmri, menon and levitin [9] clearly found for the first time that listening to music strongly modulates activity in a network of mesolimbic structures involved in reward processing including the nucleus accumbens (nac) and the ventral tegmental area (vta), as well as the hypothalamus, and insula, which are thought to be involved in regulating autonomic and physiological responses to rewarding and emotional stimuli. |
2010-05-07 |
2023-08-12 |
human |
| Elisa Mura, Stefania Preda, Stefano Govoni, Cristina Lanni, Luigia Trabace, Massimo Grilli, Federica Lagomarsino, Anna Pittaluga, Mario March. Specific neuromodulatory actions of amyloid-beta on dopamine release in rat nucleus accumbens and caudate putamen. Journal of Alzheimer's disease : JAD. vol 19. issue 3. 2010-05-05. PMID:20157258. |
we previously demonstrated that amyloid-beta (abeta) has a neuromodulatory action in the nucleus accumbens (nac). |
2010-05-05 |
2023-08-12 |
rat |
| Sarah Threlfell, Michael A Clements, Tansi Khodai, Ilse S Pienaar, Richard Exley, Jürgen Wess, Stephanie J Crag. Striatal muscarinic receptors promote activity dependence of dopamine transmission via distinct receptor subtypes on cholinergic interneurons in ventral versus dorsal striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 9. 2010-05-05. PMID:20203199. |
in nucleus accumbens (nac) core or shell, machr function was prevented in m(4)-knock-outs, but not m(2)- or m(5)-knock-outs. |
2010-05-05 |
2023-08-12 |
mouse |
| Davide Quarta, Enzo Valerio, Daniel M Hutcheson, Gael Hedou, Christian Heidbrede. The orexin-1 receptor antagonist SB-334867 reduces amphetamine-evoked dopamine outflow in the shell of the nucleus accumbens and decreases the expression of amphetamine sensitization. Neurochemistry international. vol 56. issue 1. 2010-05-04. PMID:19737591. |
orexin-expressing neurons are present in hypothalamic nuclei and send projections toward mesolimbic regions such as the nucleus accumbens (nac), a key brain region implicated in the processing of the motivational significance of reinforcers. |
2010-05-04 |
2023-08-12 |
rat |
| Rebecca L Leshan, Darren M Opland, Gwendolyn W Louis, Gina M Leinninger, Christa M Patterson, Christopher J Rhodes, Heike Münzberg, Martin G Myer. Ventral tegmental area leptin receptor neurons specifically project to and regulate cocaine- and amphetamine-regulated transcript neurons of the extended central amygdala. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 16. 2010-05-04. PMID:20410123. |
also, leprb-egfpf mice (which label projections from leprb neurons throughout the brain) reveal that few leprb neurons project to the nucleus accumbens (nac). |
2010-05-04 |
2023-08-12 |
mouse |
| Marwan N Baliki, Paul Y Geha, Howard L Fields, A Vania Apkaria. Predicting value of pain and analgesia: nucleus accumbens response to noxious stimuli changes in the presence of chronic pain. Neuron. vol 66. issue 1. 2010-05-03. PMID:20399736. |
however, nucleus accumbens (nac) activity differentiated the groups at a very high accuracy, exhibiting phasic and tonic responses with distinct properties. |
2010-05-03 |
2023-08-12 |
human |
| Lei Wang, Zhigang Lv, Zhaoyang Hu, Jian Sheng, Bin Hui, Jie Sun, Lan M. Chronic cocaine-induced H3 acetylation and transcriptional activation of CaMKIIalpha in the nucleus accumbens is critical for motivation for drug reinforcement. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 4. 2010-04-28. PMID:20010550. |
daily histone deacetylase (hdac) inhibitor infusions in the shell of the nucleus accumbens (nac) caused an upward shift in the dose-response curve under fixed-ratio schedule and increased the break point under progressive-ratio schedule, indicating enhanced motivation for self-administered drug. |
2010-04-28 |
2023-08-12 |
rat |
| Francesca M Filbey, Joseph P Schacht, Ursula S Myers, Robert S Chavez, Kent E Hutchiso. Individual and additive effects of the CNR1 and FAAH genes on brain response to marijuana cues. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 4. 2010-04-28. PMID:20010552. |
the faah group contrasts showed that faah rs324420 c homozygotes also had greater activation in widespread areas within the reward circuit, specifically in the ofc, acg, and nucleus accumbens (nac), as compared with the faah a-allele carriers. |
2010-04-28 |
2023-08-12 |
human |