| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jill Watson, Sara Guzzetti, Carlotta Franchi, Angelo Di Clemente, Silvia Burbassi, Zsuzsa Emri, Nathalie Leresche, H Rheinallt Parri, Vincenzo Crunelli, Luigi Cerv. Gamma-hydroxybutyrate does not maintain self-administration but induces conditioned place preference when injected in the ventral tegmental area. The international journal of neuropsychopharmacology. vol 13. issue 2. 2010-04-27. PMID:19573264. |
the nucleus accumbens (nac), are available. |
2010-04-27 |
2023-08-12 |
rat |
| Michael Krause, P Walter German, Sharif A Taha, Howard L Field. A pause in nucleus accumbens neuron firing is required to initiate and maintain feeding. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 13. 2010-04-22. PMID:20357125. |
nucleus accumbens (nac) inactivation increases food intake, indicating that nac neurons exert ongoing inhibition of feeding. |
2010-04-22 |
2023-08-12 |
Not clear |
| Yu Dong, Tianxiang Zhang, Wei Li, William M Doyon, William Doyon, John A Dan. Route of nicotine administration influences in vivo dopamine neuron activity: habituation, needle injection, and cannula infusion. Journal of molecular neuroscience : MN. vol 40. issue 1-2. 2010-04-21. PMID:19714495. |
nicotine activates midbrain da neurons and, consequently, elevates da concentrations in targets, especially in the nucleus accumbens (nac) of the ventral striatum. |
2010-04-21 |
2023-08-12 |
rat |
| Ping Mu, Jason T Moyer, Masago Ishikawa, Yonghong Zhang, Jaak Panksepp, Barbara A Sorg, Oliver M Schlüter, Yan Don. Exposure to cocaine dynamically regulates the intrinsic membrane excitability of nucleus accumbens neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 10. 2010-04-09. PMID:20220002. |
drug-induced malfunction of nucleus accumbens (nac) neurons underlies a key pathophysiology of drug addiction. |
2010-04-09 |
2023-08-12 |
rat |
| Nandakumar S Narayanan, Douglas J Guarnieri, Ralph J DiLeon. Metabolic hormones, dopamine circuits, and feeding. Frontiers in neuroendocrinology. vol 31. issue 1. 2010-04-08. PMID:19836414. |
the vta is the origin of mesolimbic dopamine neurons that project to the nucleus accumbens (nac) to influence behavior. |
2010-04-08 |
2023-08-12 |
Not clear |
| Matthew J Fell, Jason S Katner, Bryan G Johnson, Albert Khilevich, Jeffrey M Schkeryantz, Kenneth W Perry, Kjell A Svensso. Activation of metabotropic glutamate (mGlu)2 receptors suppresses histamine release in limbic brain regions following acute ketamine challenge. Neuropharmacology. vol 58. issue 3. 2010-04-07. PMID:19951716. |
ketamine (25 mg/kg) increased ha in the medial prefrontal cortex (mpfc), ventral hippocampus (vhipp) and the nucleus accumbens (nac) shell. |
2010-04-07 |
2023-08-12 |
rat |
| Cheryl A Frye, Sandra M Petralia, Madeline E Rhodes, Joseph F DeBol. 6-hydroxydopamine lesions enhance progesterone-facilitated lordosis of rats and hamsters, independent of effects on motor behavior. Physiology & behavior. vol 99. issue 2. 2010-04-05. PMID:19778544. |
we investigated the importance of dopaminergic neurons in the vta, and two dopaminergic projection sites, the nucleus accumbens (nac), and caudate nucleus of the striatum (cn), in modulating p(4)-facilitated sex and motor behavior. |
2010-04-05 |
2023-08-12 |
rat |
| N S Tannu, L L Howell, S E Hemb. Integrative proteomic analysis of the nucleus accumbens in rhesus monkeys following cocaine self-administration. Molecular psychiatry. vol 15. issue 2. 2010-03-30. PMID:18504425. |
the reinforcing effects and long-term consequences of cocaine self-administration have been associated with brain regions of the mesolimbic dopamine pathway, namely the nucleus accumbens (nac). |
2010-03-30 |
2023-08-12 |
human |
| Helga Höifödt Lidö, Rosita Stomberg, Anne Fagerberg, Mia Ericson, Bo Söderpal. The glycine reuptake inhibitor org 25935 interacts with basal and ethanol-induced dopamine release in rat nucleus accumbens. Alcoholism, clinical and experimental research. vol 33. issue 7. 2010-03-26. PMID:19389199. |
the mesolimbic dopamine (da) projection from the ventral tegmental area to nucleus accumbens (nac), a central part of the reward system, is activated by ethanol (etoh) and other drugs of abuse. |
2010-03-26 |
2023-08-12 |
rat |
| Pedro Rada, Jessica R Barson, Sarah F Leibowitz, Bartley G Hoebe. Opioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens. Brain research. vol 1312. 2010-03-25. PMID:19948154. |
the experimental question is whether hypothalamic opioids, known to stimulate consummatory behavior, control a link to the nucleus accumbens (nac). |
2010-03-25 |
2023-08-12 |
rat |
| Irene Yaroslavsky, Shanaz M Tejani-But. Voluntary alcohol consumption alters stress-induced changes in dopamine-2 receptor binding in Wistar-Kyoto rat brain. Pharmacology, biochemistry, and behavior. vol 94. issue 3. 2010-03-23. PMID:19896970. |
quantitative autoradiography experiments showed that chronic stress increased d2 receptor binding in the caudate putamen (cpu), nucleus accumbens (nac), substantia nigra (sn) and ventral tegmental area (vta) of wky rats, and reduced receptor binding in the cpu and sn of wis rats. |
2010-03-23 |
2023-08-12 |
rat |
| Joshua W Cordeira, Lauren Frank, Miguel Sena-Esteves, Emmanuel N Pothos, Maribel Rio. Brain-derived neurotrophic factor regulates hedonic feeding by acting on the mesolimbic dopamine system. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 7. 2010-03-19. PMID:20164338. |
moreover, amperometric recordings in brain slices of mice depleted of central bdnf uncovered marked deficits in evoked release of dopamine in the nucleus accumbens (nac) shell and dorsal striatum but normal secretion in the nac core. |
2010-03-19 |
2023-08-12 |
mouse |
| K D Carr, L S Chau, S Cabeza de Vaca, K Gustafson, M Stouffer, D S Tukey, S Restituito, E B Zif. AMPA receptor subunit GluR1 downstream of D-1 dopamine receptor stimulation in nucleus accumbens shell mediates increased drug reward magnitude in food-restricted rats. Neuroscience. vol 165. issue 4. 2010-03-12. PMID:19931598. |
previous findings suggest that neuroadaptations downstream of d-1 dopamine (da) receptor stimulation in nucleus accumbens (nac) are involved in the enhancement of drug reward by chronic food restriction (fr). |
2010-03-12 |
2023-08-12 |
rat |
| N Kitanaka, J Kitanaka, K Watabe, M Takemur. Low-dose pretreatment with clorgyline decreases the levels of 3-methoxy-4-hydroxyphenylglycol in the striatum and nucleus accumbens and attenuates methamphetamine-induced conditioned place preference in rats. Neuroscience. vol 165. issue 4. 2010-03-12. PMID:19958817. |
neurochemical analysis using high-performance liquid chromatography revealed that the tissue levels of monoamines and their metabolites were not significantly affected by treatment with 0.1 mg/kg clorgyline except for the levels of 3-methoxy4-hydroxyphenylglycol (mhpg) in the striatum and nucleus accumbens (nac). |
2010-03-12 |
2023-08-12 |
rat |
| Deranda B Lester, Anthony D Miller, Charles D Blah. Muscarinic receptor blockade in the ventral tegmental area attenuates cocaine enhancement of laterodorsal tegmentum stimulation-evoked accumbens dopamine efflux in the mouse. Synapse (New York, N.Y.). vol 64. issue 3. 2010-03-02. PMID:19862686. |
the reinforcing properties of cocaine have been related to increased extracellular concentrations of dopamine in the nucleus accumbens (nac). |
2010-03-02 |
2023-08-12 |
mouse |
| Brandon J Aragona, Jeremy J Day, Mitchell F Roitman, Nathan A Cleaveland, R Mark Wightman, Regina M Carell. Regional specificity in the real-time development of phasic dopamine transmission patterns during acquisition of a cue-cocaine association in rats. The European journal of neuroscience. vol 30. issue 10. 2010-02-26. PMID:19912327. |
drug seeking is significantly regulated by drug-associated cues and associative learning between environmental cues and cocaine reward is mediated by dopamine transmission within the nucleus accumbens (nac). |
2010-02-26 |
2023-08-12 |
rat |
| Zheng-Xiong Xi, Michael Kiyatkin, Xia Li, Xiao-Qing Peng, Armina Wiggins, Krista Spiller, Jie Li, Eliot L Gardne. N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self-administration and cocaine-enhanced brain-stimulation reward in rats. Neuropharmacology. vol 58. issue 1. 2010-02-25. PMID:19559037. |
in vivo microdialysis demonstrated that 2-pmpa (10, 30, 100 mg/kg) dose-dependently attenuated cocaine-enhanced extracellular dopamine (da) in the nucleus accumbens (nac). |
2010-02-25 |
2023-08-12 |
rat |
| Jing Liang, Xing-Jie Ping, Yi-Jing Li, Yao-Ying Ma, Liu-Zhen Wu, Ji-Sheng Han, Cai-Lian Cu. Morphine-induced conditioned place preference in rats is inhibited by electroacupuncture at 2 Hz: role of enkephalin in the nucleus accumbens. Neuropharmacology. vol 58. issue 1. 2010-02-25. PMID:19596017. |
or lesion in the nucleus accumbens (nac), providing evidence that endogenous opioid system in the nac mediates the effects of ea. |
2010-02-25 |
2023-08-12 |
rat |
| E Rodríguez-Borrero, F Rivera-Escalera, F Candelas, J Montalvo, W J Muñoz-Miranda, J R Walker, C S Maldonado-Vlaa. Arginine vasopressin gene expression changes within the nucleus accumbens during environment elicited cocaine-conditioned response in rats. Neuropharmacology. vol 58. issue 1. 2010-02-25. PMID:19596360. |
it is known that changes in gene expression within the nucleus accumbens (nac) occur during cocaine dependence development. |
2010-02-25 |
2023-08-12 |
human |
| Vijay Chandrasekar, Jean-Luc Dreye. The brain-specific Neural Zinc Finger transcription factor 2b (NZF-2b/7ZFMyt1) causes suppression of cocaine-induced locomotor activity. Neurobiology of disease. vol 37. issue 1. 2010-02-22. PMID:19786102. |
chronic cocaine induces high expression of the brain-specific neural-zinc-finger transcription factor-2b (nzf-2b/7zfmyt1), particularly in the mesolimbic dopaminergic pathway, resulting in a 11-fold increase in nzf-2b/7zfmyt1 expression in the nucleus accumbens (nac). |
2010-02-22 |
2023-08-12 |
Not clear |