| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marina E Wolf, Carrie R Ferrari. AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine. Neuroscience and biobehavioral reviews. vol 35. issue 2. 2011-02-17. PMID:20109488. |
this review focuses on cocaine-induced postsynaptic plasticity in the nucleus accumbens (nac) involving changes in ampa receptor (ampar) transmission. |
2011-02-17 |
2023-08-12 |
Not clear |
| T Tsurugizawa, A Uematsu, H Uneyama, K Tori. The role of the GABAergic and dopaminergic systems in the brain response to an intragastric load of alcohol in conscious rats. Neuroscience. vol 171. issue 2. 2011-02-17. PMID:20849934. |
an intragastrically infused 10% ethanol solution induced a significant decrease in the intensity of the bold signal in several regions of the brain, including the bilateral amygdala (amg), nucleus accumbens (nac), hippocampus, ventral pallidum, insular cortex, and cingulate cortex, and an increase in the bold signal in the ventral tegmental area (vta) and hypothalamic regions. |
2011-02-17 |
2023-08-12 |
rat |
| Kaili Anier, Kristina Malinovskaja, Anu Aonurm-Helm, Alexander Zharkovsky, Anti Kald. DNA methylation regulates cocaine-induced behavioral sensitization in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 12. 2011-02-16. PMID:20720536. |
we report that acute cocaine treatment caused an upregulation of dnmt3a and dnmt3b gene expression in the nucleus accumbens (nac). |
2011-02-16 |
2023-08-12 |
mouse |
| Mitchell F Roitman, Robert A Wheeler, Paul H E Tiesinga, Jamie D Roitman, Regina M Carell. Hedonic and nucleus accumbens neural responses to a natural reward are regulated by aversive conditioning. Learning & memory (Cold Spring Harbor, N.Y.). vol 17. issue 11. 2011-02-11. PMID:20971936. |
the nucleus accumbens (nac) plays a role in hedonic reactivity to taste stimuli. |
2011-02-11 |
2023-08-12 |
rat |
| Thomas P Giordano, Thomas F Tropea, Shirish S Satpute, Martina J Sinnegger-Brauns, Joerg Striessnig, Barry E Kosofsky, Anjali M Rajadhyaksh. Molecular switch from L-type Ca v 1.3 to Ca v 1.2 Ca2+ channel signaling underlies long-term psychostimulant-induced behavioral and molecular plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 50. 2011-02-09. PMID:21159975. |
molecular studies to further elucidate the role of ca(v)1.2 versus ca(v)1.3 ltccs in activating signaling pathways in the nucleus accumbens (nac) of drug-naive versus drug-preexposed mice examined 14 d later revealed that an acute amphetamine and cocaine challenge in drug-naive mice increases ser133 camp response element-binding protein (creb) phosphorylation in the nac via ca(v)1.3 channels and via a dopamine d(1)-dependent mechanism, independent of the extracellular signal-regulated kinase (erk) pathway, an important mediator of psychostimulant-induced plasticity. |
2011-02-09 |
2023-08-12 |
mouse |
| K K Pitchers, K S Frohmader, V Vialou, E Mouzon, E J Nestler, M N Lehman, L M Coole. ΔFosB in the nucleus accumbens is critical for reinforcing effects of sexual reward. Genes, brain, and behavior. vol 9. issue 7. 2011-02-08. PMID:20618447. |
sexual experience was shown to cause Δfosb accumulation in several limbic brain regions including the nucleus accumbens (nac), medial prefrontal cortex, ventral tegmental area and caudate putamen but not the medial preoptic nucleus. |
2011-02-08 |
2023-08-12 |
rat |
| Mark C Moffett, Jane Song, Michael J Kuha. CART peptide inhibits locomotor activity induced by simultaneous stimulation of D1 and D2 receptors, but not by stimulation of individual dopamine receptors. Synapse (New York, N.Y.). vol 65. issue 1. 2011-02-04. PMID:20506412. |
previously, our laboratory demonstrated that injections of cart peptide (cart 55-102) into the nucleus accumbens (nac) attenuated both cocaine- and dopamine-induced increases in locomotor activity (lma), and attenuated cocaine reward as well. |
2011-02-04 |
2023-08-12 |
rat |
| Carrie R Ferrario, Xuan Li, Marina E Wol. Effects of acute cocaine or dopamine receptor agonists on AMPA receptor distribution in the rat nucleus accumbens. Synapse (New York, N.Y.). vol 65. issue 1. 2011-02-04. PMID:20506566. |
changes in α-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor (ampar) surface expression in the rodent nucleus accumbens (nac) are produced by cocaine exposure and implicated in addiction-related behaviors. |
2011-02-04 |
2023-08-12 |
rat |
| Joost Wiskerke, Dustin Schetters, Inge E van Es, Yvar van Mourik, Bjørnar R O den Hollander, Anton N M Schoffelmeer, Tommy Patti. μ-Opioid receptors in the nucleus accumbens shell region mediate the effects of amphetamine on inhibitory control but not impulsive choice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 1. 2011-02-04. PMID:21209211. |
intracranial infusions of naloxone, the selective μ-opioid receptor antagonist ctap (h-d-phe-cys-tyr-d-trp-arg-thr-pen-thr-nh(2)), morphine, and the selective μ-opioid receptor agonist damgo ([d-ala(2),n-me-phe(4),gly(5)-ol]-enkephalin acetate salt) revealed that μ-opioid receptor activation in the shell rather than the core subregion of the nucleus accumbens (nac) modulates inhibitory control and subserves the effect of amphetamine thereon. |
2011-02-04 |
2023-08-12 |
rat |
| Daniel J Christoffel, Sam A Golden, Dani Dumitriu, Alfred J Robison, William G Janssen, H Francisca Ahn, Vaishnav Krishnan, Cindy M Reyes, Ming-Hu Han, Jessica L Ables, Amelia J Eisch, David M Dietz, Deveroux Ferguson, Rachael L Neve, Paul Greengard, Yong Kim, John H Morrison, Scott J Russ. IκB kinase regulates social defeat stress-induced synaptic and behavioral plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 1. 2011-02-04. PMID:21209217. |
the neurobiological underpinnings of mood and anxiety disorders have been linked to the nucleus accumbens (nac), a region important in processing the rewarding and emotional salience of stimuli. |
2011-02-04 |
2023-08-12 |
mouse |
| Yue Cui, X Q Zhang, Y Cui, W J Xin, J Jing, X G Li. Activation of phosphatidylinositol 3-kinase/Akt-mammalian target of Rapamycin signaling pathway in the hippocampus is essential for the acquisition of morphine-induced place preference in rats. Neuroscience. vol 171. issue 1. 2011-02-02. PMID:20826199. |
our results showed that the acquisition of morphine cpp increased phosphorylation of akt in the hippocampal ca3, but not in the nucleus accumbens (nac), the ventral tegmental area (vta) or the ca1. |
2011-02-02 |
2023-08-12 |
rat |
| I Morganstern, G-Q Chang, Y-W Chen, J R Barson, Y Zhiyu, B G Hoebel, S F Leibowit. Role of melanin-concentrating hormone in the control of ethanol consumption: Region-specific effects revealed by expression and injection studies. Physiology & behavior. vol 101. issue 4. 2011-01-28. PMID:20670637. |
compared to saline, mch injected in the paraventricular nucleus (pvn) and nucleus accumbens (nac) selectively stimulated ethanol consumption without affecting food or water intake. |
2011-01-28 |
2023-08-12 |
rat |
| Zachary M Jeanes, Tavanna R Buske, Richard A Morriset. In vivo chronic intermittent ethanol exposure reverses the polarity of synaptic plasticity in the nucleus accumbens shell. The Journal of pharmacology and experimental therapeutics. vol 336. issue 1. 2011-01-18. PMID:20947635. |
glutamatergic synaptic plasticity in the nucleus accumbens (nac) is implicated in response to sensitization to psychomotor-stimulating agents, yet ethanol effects here are undefined. |
2011-01-18 |
2023-08-12 |
mouse |
| Alexis Faure, Jocelyn M Richard, Kent C Berridg. Desire and dread from the nucleus accumbens: cortical glutamate and subcortical GABA differentially generate motivation and hedonic impact in the rat. PloS one. vol 5. issue 6. 2011-01-13. PMID:20585461. |
gabaergic signals to the nucleus accumbens (nac) shell arise from predominantly subcortical sources whereas glutamatergic signals arise mainly from cortical-related sources. |
2011-01-13 |
2023-08-12 |
rat |
| George A Rogge, Li-Ling Shen, Michael J Kuha. Chromatin immunoprecipitation assays revealed CREB and serine 133 phospho-CREB binding to the CART gene proximal promoter. Brain research. vol 1344. 2011-01-10. PMID:20451507. |
both over expression of cyclic amp response element binding protein (creb) in the nucleus accumbens (nac), and intra-accumbal injection of cocaine- and amphetamine-regulated transcript (cart) peptides, have been shown to decrease cocaine reward. |
2011-01-10 |
2023-08-12 |
rat |
| Brad A Grueter, Gabor Brasnjo, Robert C Malenk. Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens. Nature neuroscience. vol 13. issue 12. 2011-01-06. PMID:21076424. |
synaptic modifications in the nucleus accumbens (nac) are important for adaptive and pathological reward-dependent learning. |
2011-01-06 |
2023-08-12 |
mouse |
| Kafui Dzirasa, Laurent Coque, Michelle M Sidor, Sunil Kumar, Elizabeth A Dancy, Joseph S Takahashi, Colleen A McClung, Miguel A L Nicoleli. Lithium ameliorates nucleus accumbens phase-signaling dysfunction in a genetic mouse model of mania. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 48. 2011-01-06. PMID:21123577. |
here we show that the phasic entrainment of nucleus accumbens (nac) low-gamma (30-55 hz) oscillations to delta (1-4 hz) oscillations is negatively correlated with the extent to which wild-type (wt) mice explore a novel environment. |
2011-01-06 |
2023-08-12 |
mouse |
| Pedro Rada, Miriam E Bocarsly, Jessica R Barson, Bartley G Hoebel, Sarah F Leibowit. Reduced accumbens dopamine in Sprague-Dawley rats prone to overeating a fat-rich diet. Physiology & behavior. vol 101. issue 3. 2011-01-05. PMID:20643155. |
obese humans and animals exhibit reduced functioning of the dopamine (da) system in the nucleus accumbens (nac). |
2011-01-05 |
2023-08-12 |
rat |
| Vincent D Costa, Peter J Lang, Dean Sabatinelli, Francesco Versace, Margaret M Bradle. Emotional imagery: assessing pleasure and arousal in the brain's reward circuitry. Human brain mapping. vol 31. issue 9. 2011-01-03. PMID:20127869. |
research on emotional perception and learning indicates appetitive cues engage nucleus accumbens (nac) and medial prefrontal cortex (mpfc), whereas amygdala activity is modulated by the emotional intensity of appetitive and aversive cues. |
2011-01-03 |
2023-08-12 |
human |
| Jun-ichi Karasawa, Makiko Kotani, Daiji Kambe, Shigeyuki Chak. AMPA receptor mediates mGlu 2/3 receptor antagonist-induced dopamine release in the rat nucleus accumbens shell. Neurochemistry international. vol 57. issue 5. 2010-12-22. PMID:20674641. |
the role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (ampa) receptor activation in the regulation of dopamine release by the metabotropic glutamate (mglu) 2/3 receptors in the nucleus accumbens (nac) shell was investigated using an in vivo microdialysis evaluation. |
2010-12-22 |
2023-08-12 |
rat |