| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Susan E Doyle, Carolina Ramôa, Garrett Garber, Joshua Newman, Zeeshan Toor, Wendy J Lync. A shift in the role of glutamatergic signaling in the nucleus accumbens core with the development of an addicted phenotype. Biological psychiatry. vol 76. issue 10. 2015-07-27. PMID:24629536. |
while dopamine signaling in the nucleus accumbens (nac) plays a well-established role in motivating cocaine use in early nonaddicted stages, recent evidence suggests that other signaling pathways may be critical once addiction has developed. |
2015-07-27 |
2023-08-12 |
Not clear |
| Margarita Arango-Lievano, Justin T Schwarz, Mary Vernov, Matthew B Wilkinson, Kathryn Bradbury, Akira Feliz, Roberta Marongiu, Yaroslav Gelfand, Jennifer Warner-Schmidt, Eric J Nestler, Paul Greengard, Scott J Russo, Michael G Kaplit. Cell-type specific expression of p11 controls cocaine reward. Biological psychiatry. vol 76. issue 10. 2015-07-27. PMID:24725970. |
limbic structures, such as the nucleus accumbens (nac), play a crucial role in both disorders, yet how different cell types within these structures contribute to the pathogenesis remains elusive. |
2015-07-27 |
2023-08-13 |
mouse |
| Ran Yu, Zheng Ye, Jing Li, Min Li, Yu Bai, Qun-wan Pa. [Wireless telemetry electrical activity of nucleus accumbens shell in morphine-induced CPP rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 31. issue 1. 2015-07-26. PMID:26016239. |
to analyse the relationship between the electrical activity changes of nucleus accumbens (nac) shell and the drug-seeking behavior by recording nac shell electrical activity in conditioned place preference (cpp) rats induced by morphine. |
2015-07-26 |
2023-08-13 |
rat |
| Edita Navratilova, Jennifer Yanhua Xie, Diana Meske, Chaoling Qu, Kozo Morimura, Alec Okun, Naohisa Arakawa, Michael Ossipov, Howard L Fields, Frank Porrec. Endogenous opioid activity in the anterior cingulate cortex is required for relief of pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 18. 2015-07-24. PMID:25948274. |
pain is aversive, and its relief elicits reward mediated by dopaminergic signaling in the nucleus accumbens (nac), a part of the mesolimbic reward motivation pathway. |
2015-07-24 |
2023-08-13 |
rat |
| Kimberley A Pitman, Ernest Puil, Stephanie L Borglan. GABA(B) modulation of dopamine release in the nucleus accumbens core. The European journal of neuroscience. vol 40. issue 10. 2015-07-23. PMID:25229321. |
modulation of the concentration of dopamine (da) released from dopaminergic terminals in the nucleus accumbens (nac) influences behaviours such as the motivation to obtain drugs of abuse. |
2015-07-23 |
2023-08-13 |
mouse |
| Rishi Sharma, Samuel Dumontier, David DeRoode, Pradeep Sahota, Mahesh M Thakka. Nicotine infusion in the wake-promoting basal forebrain enhances alcohol-induced activation of nucleus accumbens. Alcoholism, clinical and experimental research. vol 38. issue 10. 2015-07-21. PMID:25336083. |
as nucleus accumbens (nac) is the terminal brain region associated with drug addiction, we hypothesize that nicotine infusion in the bf may enhance alcohol-induced activation of nac. |
2015-07-21 |
2023-08-13 |
Not clear |
| Ken T Wakabayashi, Eugene A Kiyatki. Behavior-associated and post-consumption glucose entry into the nucleus accumbens extracellular space during glucose free-drinking in trained rats. Frontiers in behavioral neuroscience. vol 9. 2015-07-20. PMID:26190984. |
here, we used glucose biosensors with high-speed amperometry to examine the pattern of phasic and tonic changes in extracellular glucose in the nucleus accumbens (nac) during unrestricted glucose-drinking in well-trained rats. |
2015-07-20 |
2023-08-13 |
rat |
| Laura E O'Dell, Luis A Natividad, Joseph A Pipkin, Francisco Roman, Ivan Torres, Jesus Jurado, Oscar V Torres, Theodore C Friedman, John M Tenayuca, Arbi Nazaria. Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes. Addiction biology. vol 19. issue 6. 2015-07-20. PMID:23834715. |
in order to examine the contribution of dopamine to our behavioral effects, dopamine transporter (dat), d1 and d2 receptor levels were compared in the nucleus accumbens (nac) following 10 days of nicotine or saline ivsa. |
2015-07-20 |
2023-08-12 |
rat |
| Joana Coutinho, Ana Filipa Ramos, Liliana Maia, Liliana Castro, Eva Conceição, Allan Geliebter, Paulo P P Machado, Óscar Gonçalves, Adriana Sampai. Volumetric alterations in the nucleus accumbens and caudate nucleus in bulimia nervosa: a structural magnetic resonance imaging study. The International journal of eating disorders. vol 48. issue 2. 2015-07-20. PMID:24634102. |
the basal ganglia specifically, the nucleus accumbens (nac) and the caudate nucleus (cn) are part of the frontostriatal circuits involved in inhibitory control. |
2015-07-20 |
2023-08-12 |
Not clear |
| Rafael Renteria, Zachary M Jeanes, Richard A Morriset. Ethanol attenuation of long-term depression in the nucleus accumbens can be overcome by activation of TRPV1 receptors. Alcoholism, clinical and experimental research. vol 38. issue 11. 2015-07-20. PMID:25421513. |
altered expression of synaptic plasticity within the nucleus accumbens (nac) constitutes a critical neuroadaptive response to ethanol (etoh) and other drugs of abuse. |
2015-07-20 |
2023-08-13 |
Not clear |
| Anushree N Karkhanis, Jason L Locke, Brian A McCool, Jeffrey L Weiner, Sara R Jone. Social isolation rearing increases nucleus accumbens dopamine and norepinephrine responses to acute ethanol in adulthood. Alcoholism, clinical and experimental research. vol 38. issue 11. 2015-07-20. PMID:25421514. |
in the nucleus accumbens (nac), dopamine (da) and norepinephrine (ne) signaling can be profoundly influenced by stress, anxiety, and drugs of abuse, including ethanol (etoh). |
2015-07-20 |
2023-08-13 |
Not clear |
| Shauna L Parkes, Laura A Bradfield, Bernard W Ballein. Interaction of insular cortex and ventral striatum mediates the effect of incentive memory on choice between goal-directed actions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 16. 2015-07-16. PMID:25904797. |
the anterior insular cortex (ic) and the nucleus accumbens (nac) core have been separately implicated in the selection and performance of actions based on the incentive value of the instrumental outcome. |
2015-07-16 |
2023-08-13 |
rat |
| Céline Devroye, Adeline Cathala, Marlène Maitre, Pier Vincenzo Piazza, Djoher Nora Abrous, Jean-Michel Revest, Umberto Spampinat. Serotonin2C receptor stimulation inhibits cocaine-induced Fos expression and DARPP-32 phosphorylation in the rat striatum independently of dopamine outflow. Neuropharmacology. vol 89. 2015-07-15. PMID:25446572. |
recent studies assessing the influence of 5-ht(2c)rs on cocaine-induced neurochemical and behavioral responses have shown that 5-ht2crs can also modulate mesoaccumbens da pathway activity at post-synaptic level, by controlling da transmission in the nucleus accumbens (nac), independently of da release itself. |
2015-07-15 |
2023-08-13 |
rat |
| Augusta Pisanu, Daniele Lecca, Valentina Valentini, Amine Bahi, Jean-Luc Dreyer, Fabio Cacciapaglia, Andrea Scifo, Giovanna Piras, Cristina Cadoni, Gaetano Di Chiar. Impairment of acquisition of intravenous cocaine self-administration by RNA-interference of dopamine D1-receptors in the nucleus accumbens shell. Neuropharmacology. vol 89. 2015-07-15. PMID:25446574. |
drug self-administration (sa) have implicated nucleus accumbens (nac) shell da in cocaine and heroin reinforcement. |
2015-07-15 |
2023-08-13 |
rat |
| Yao Lu, Nicolette Driscoll, Ilker Ozden, Zeyang Yu, Arto V Nurmikk. Modulating dopamine release by optogenetics in transgenic mice reveals terminal dopaminergic dynamics. Neurophotonics. vol 2. issue 3. 2015-07-14. PMID:26171413. |
dopamine (da) release and uptake dynamics in the nucleus accumbens (nac) have important implications for neurological diseases and mammalian animal behaviors. |
2015-07-14 |
2023-08-13 |
mouse |
| Haiyin Wu, Brian O'Neill, Dawn D Han, Keerthi Thirtamara-Rajamani, Yanlin Wang, Howard H G. Restoration of cocaine stimulation and reward by reintroducing wild type dopamine transporter in adult knock-in mice with a cocaine-insensitive dopamine transporter. Neuropharmacology. vol 86. 2015-07-14. PMID:24835281. |
in an earlier study we showed that aav-datwt injections in regions covering the lateral nucleus accumbens (nac) and lateral caudate-putamen (cpu) restored cocaine stimulation but not cocaine reward. |
2015-07-14 |
2023-08-13 |
mouse |
| Courtney M Cameron, R Mark Wightman, Regina M Carell. Dynamics of rapid dopamine release in the nucleus accumbens during goal-directed behaviors for cocaine versus natural rewards. Neuropharmacology. vol 86. 2015-07-14. PMID:25174553. |
electrophysiological studies show that distinct subsets of nucleus accumbens (nac) neurons differentially encode information about goal-directed behaviors for intravenous cocaine versus natural (food/water) rewards. |
2015-07-14 |
2023-08-13 |
rat |
| D García-Pérez, F Sáez-Belmonte, M L Laorden, C Núñez, M V Milané. Morphine administration modulates expression of Argonaute 2 and dopamine-related transcription factors involved in midbrain dopaminergic neurons function. British journal of pharmacology. vol 168. issue 8. 2015-07-13. PMID:23215787. |
we have examined the effects of acute and chronic morphine and morphine withdrawal on th expression and activity as well as expression of nurr1, pitx3 and ago2 in the ventral tegmental area (vta) and nucleus accumbens (nac) of the rat. |
2015-07-13 |
2023-08-12 |
rat |
| Ninglei Sun, Steven R Laviolett. Dopamine receptor blockade modulates the rewarding and aversive properties of nicotine via dissociable neuronal activity patterns in the nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 12. 2015-07-10. PMID:24896614. |
the mesolimbic pathway comprising the ventral tegmental area (vta) and projection terminals in the nucleus accumbens (nac) has been identified as a critical neural system involved in processing both the rewarding and aversive behavioral effects of nicotine. |
2015-07-10 |
2023-08-13 |
Not clear |
| Jun Zhu, Narasimha M Midde, Adrian M Gomez, Wei-Lun Sun, Steven B Harro. Intra-ventral tegmental area HIV-1 Tat1-86 attenuates nicotine-mediated locomotor sensitization and alters mesocorticolimbic ERK and CREB signaling in rats. Frontiers in microbiology. vol 6. 2015-07-07. PMID:26150803. |
further, we examined the phosphorylated levels of creb (pcreb) and erk1/2 (perk1/2) in the prefrontal cortex (pfc), nucleus accumbens (nac) and vta. |
2015-07-07 |
2023-08-13 |
rat |