| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anushree N Karkhanis, Jamie H Rose, Kimberly N Huggins, Joanne K Konstantopoulos, Sara R Jone. Chronic intermittent ethanol exposure reduces presynaptic dopamine neurotransmission in the mouse nucleus accumbens. Drug and alcohol dependence. vol 150. 2015-10-28. PMID:25765483. |
increasing evidence suggests that chronic ethanol exposure decreases dopamine (da) neurotransmission in the nucleus accumbens (nac), contributing to a hypodopaminergic state during withdrawal. |
2015-10-28 |
2023-08-13 |
mouse |
| Masahiro Sawada, Kenji Kato, Takeharu Kunieda, Nobuhiro Mikuni, Susumu Miyamoto, Hirotaka Onoe, Tadashi Isa, Yukio Nishimur. Function of the nucleus accumbens in motor control during recovery after spinal cord injury. Science (New York, N.Y.). vol 350. issue 6256. 2015-10-28. PMID:26430122. |
it is generally thought that the nucleus accumbens (nac) regulates motivation-driven effort but is not involved in the direct control of movement. |
2015-10-28 |
2023-08-13 |
monkey |
| Hongjie Chen, Hao Qiang, Kaichun Fan, Shousen Wang, Zhaocong Zhen. The snoRNA MBII-52 regulates cocaine-induced conditioned place preference and locomotion in mice. PloS one. vol 9. issue 6. 2015-10-26. PMID:24979384. |
cocaine dependence involves in the brain's reward circuit as well as nucleus accumbens (nac), a key region of the mesolimbic dopamine pathway. |
2015-10-26 |
2023-08-13 |
mouse |
| Gianluigi Tanda, Valentina Valentini, Maria Antonietta De Luca, Valentina Perra, Gian Pietro Serra, Gaetano Di Chiar. A systematic microdialysis study of dopamine transmission in the accumbens shell/core and prefrontal cortex after acute antipsychotics. Psychopharmacology. vol 232. issue 8. 2015-10-26. PMID:25345736. |
the only systematic in vivo studies comparing antipsychotic (ap) effects on nucleus accumbens (nac) shell and core dopamine (da) transmission are voltammetric studies performed in pargyline-pretreated, halothane-anaesthetized rats. |
2015-10-26 |
2023-08-13 |
rat |
| Shin-ichi Adachi, Ai Eguchi, Kazuhiro Sakamoto, Hiroki Asano, Yasuko Manabe, Shigenobu Matsumura, Satoshi Tsuzuki, Kazuo Inoue, Tohru Fushik. Behavioral palatability of dietary fatty acids correlates with the intracellular calcium ion levels induced by the fatty acids in GPR120-expressing cells. Biomedical research (Tokyo, Japan). vol 35. issue 6. 2015-10-22. PMID:25743342. |
we also showed that the lcfa (1% linoleic acid) increased the extracellular dopamine (da) level in the nucleus accumbens (nac), which participates in reward behavior. |
2015-10-22 |
2023-08-13 |
mouse |
| Fawaz Alasmari, Sawsan Abuhamdah, Youssef Sar. Effects of ampicillin on cystine/glutamate antiporter and glutamate transporter 1 isoforms as well as ethanol drinking in male P rats. Neuroscience letters. vol 600. 2015-10-22. PMID:26071905. |
we found recently that β-lactam antibiotic, ampicillin, upregulated glt-1 expression in the prefrontal cortex (pfc) and nucleus accumbens (nac) and consequently reduced ethanol intake in alcohol-preferring (p) rats. |
2015-10-22 |
2023-08-13 |
human |
| J A D Dela Cruz, T Coke, T Karagiorgis, C Sampson, D Icaza-Cukali, K Kest, R Ranaldi, R J Bodna. c-Fos induction in mesotelencephalic dopamine pathway projection targets and dorsal striatum following oral intake of sugars and fats in rats. Brain research bulletin. vol 111. 2015-10-22. PMID:25460109. |
dopamine (da) signaling in the medial prefrontal cortex (mpfc), the amygdala (amy) and the nucleus accumbens (nac), has been implicated in acquisition and expression of fat- and sugar-cfp. |
2015-10-22 |
2023-08-13 |
rat |
| Kathryn J Reissner, Cassandra D Gipson, Phuong K Tran, Lori A Knackstedt, Michael D Scofield, Peter W Kaliva. Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement. Addiction biology. vol 20. issue 2. 2015-10-21. PMID:24612076. |
rats were pre-treated in the nucleus accumbens with vivo-morpholino antisense oligomers targeting either glt-1 or xct (catalytic subunit of the cystine-glutamate exchanger) overlapping with daily nac administration during extinction (100 mg/kg, i.p. |
2015-10-21 |
2023-08-12 |
rat |
| J Sun, N J Cairns, J S Perlmutter, R H Mach, J X. Regulation of dopamine D₃ receptor in the striatal regions and substantia nigra in diffuse Lewy body disease. Neuroscience. vol 248. 2015-10-20. PMID:23732230. |
dopamine d₃ receptor density was significantly increased in the striatal regions including caudate, putamen and nucleus accumbens (nac). |
2015-10-20 |
2023-08-12 |
Not clear |
| M E Bocarsly, N M Aven. A high-fat diet or galanin in the PVN decreases phosphorylation of CREB in the nucleus accumbens. Neuroscience. vol 248. 2015-10-20. PMID:23747305. |
gal has recently been shown to inhibit opiate reward, which in turn, decreases camp response element-binding protein (creb) in the nucleus accumbens (nac). |
2015-10-20 |
2023-08-12 |
rat |
| Shuntaro Kohnomi, Shiro Konish. Multiple actions of a D₃ dopamine receptor agonist, PD128907, on GABAergic inhibitory transmission between medium spiny neurons in mouse nucleus accumbens shell. Neuroscience letters. vol 600. 2015-10-19. PMID:26033184. |
the nucleus accumbens (nac) plays a crucial role in pathophysiological responses, such as reward-related behaviors, addiction, depression and schizophrenia, through activation of dopaminergic system in the midbrain area. |
2015-10-19 |
2023-08-13 |
mouse |
| Marzieh Moradi, Zahra Fatahi, Abbas Haghparas. Blockade of D1-like dopamine receptors within the ventral tegmental area and nucleus accumbens attenuates antinociceptive responses induced by chemical stimulation of the lateral hypothalamus. Neuroscience letters. vol 599. 2015-10-16. PMID:26022630. |
previous studies showed a role for the ventral tegmental area (vta) and nucleus accumbens (nac) in antinociception induced by lh stimulation through the orexinergic system. |
2015-10-16 |
2023-08-13 |
rat |
| Marc T J Exton-McGuinness, Jonathan L C Le. Reduction in Responding for Sucrose and Cocaine Reinforcement by Disruption of Memory Reconsolidation eNeuro. vol 2. issue 2. 2015-10-14. PMID:26464973. |
we went on to investigate the potential role of the nucleus accumbens (nac) in the reconsolidation of sucrose-reinforced instrumental memories, showing that co-infusion of the nmdar antagonist 2-amino-5-phosphonopentanoic acid (ap-5) and the dopamine-1 receptor (d1r) antagonist 7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol (sch23390) into the nac prior to memory reactivation impaired reconsolidation; however, there was no effect when these drugs were infused alone. |
2015-10-14 |
2023-08-13 |
rat |
| Erin K Z Kirschmann, Jocelyn C Mauna, Cory M Willis, Rebecca L Foster, Amanda M Chipman, Edda Thiel. Appetitive cue-evoked ERK signaling in the nucleus accumbens requires NMDA and D1 dopamine receptor activation and regulates CREB phosphorylation. Learning & memory (Cold Spring Harbor, N.Y.). vol 21. issue 11. 2015-10-13. PMID:25322796. |
we previously demonstrated that exposure to an appetitive cs causes an increase in the activation of extracellular signal-regulated kinase (erk) and cyclic-amp response-element binding protein (creb) in the nucleus accumbens (nac) of rats, and that cs-evoked erk activation is critical for cs control over reward seeking. |
2015-10-13 |
2023-08-13 |
rat |
| Amarilys Morales-Rivera, Mayté M Hernández-Burgos, Arlene Martínez-Rivera, Jeremy Pérez-Colón, Raymond Rivera, Janitza Montalvo, Enrique Rodríguez-Borrero, Carmen S Maldonado-Vlaa. Anxiolytic effects of oxytocin in cue-induced cocaine seeking behavior in rats. Psychopharmacology. vol 231. issue 21. 2015-10-12. PMID:24760374. |
moreover, previous data have demonstrated an increase in mrna ot levels within the nucleus accumbens (nac) following acute and chronic cocaine exposure in rats. |
2015-10-12 |
2023-08-13 |
rat |
| Ken T Wakabayashi, Suelynn E Ren, Eugene A Kiyatki. Methylenedioxypyrovalerone (MDPV) mimics cocaine in its physiological and behavioral effects but induces distinct changes in NAc glucose. Frontiers in neuroscience. vol 9. 2015-10-07. PMID:26441499. |
recently, we showed that intravenous cocaine induces rapid rise in nucleus accumbens (nac) glucose and established its relation to neural activation triggered by the peripheral drug actions. |
2015-10-07 |
2023-08-13 |
rat |
| Mei Huang, Anna R Felix, Dorothy G Flood, Chaya Bhuvaneswaran, Dana Hilt, Gerhard Koenig, Herbert Y Meltze. The novel α7 nicotinic acetylcholine receptor agonist EVP-6124 enhances dopamine, acetylcholine, and glutamate efflux in rat cortex and nucleus accumbens. Psychopharmacology. vol 231. issue 23. 2015-10-07. PMID:24810107. |
increased release of dopamine (da), acetylcholine (ach), glutamate (glu), and γ-aminobutyric acid (gaba) in cerebral cortex, hippocampus, and nucleus accumbens (nac) has been suggested to contribute to their beneficial effects on cognition. |
2015-10-07 |
2023-08-13 |
rat |
| Jennifer Y Xie, Chaoling Qu, Amol Patwardhan, Michael H Ossipov, Edita Navratilova, Lino Becerra, David Borsook, Frank Porrec. Activation of mesocorticolimbic reward circuits for assessment of relief of ongoing pain: a potential biomarker of efficacy. Pain. vol 155. issue 8. 2015-10-07. PMID:24861580. |
medications commonly used clinically, including gabapentin and nonsteroidal anti-inflammatory drugs (nsaids), were evaluated in models of post-surgical (1 day after incision) or neuropathic (14 days after spinal nerve ligation [snl]) pain to determine whether the clinical efficacy profile of these drugs in these pain conditions was reflected by extracellular dopamine (da) release in the nucleus accumbens (nac) shell. |
2015-10-07 |
2023-08-13 |
rat |
| Z Yong, L Yan, X Gao, Z Gong, R S. Effects of thienorphine on synaptic structure and synaptophysin expression in the rat nucleus accumbens. Neuroscience. vol 274. 2015-10-07. PMID:24861887. |
however, its effect on synaptic plasticity in the nac (nucleus accumbens) remains unclear. |
2015-10-07 |
2023-08-13 |
rat |
| Edward P Retzbach, Paulomi H Dholakia, Elizabeth A Duncan-Vaidy. The effect of daily caffeine exposure on lever-pressing for sucrose and c-Fos expression in the nucleus accumbens in the rat. Physiology & behavior. vol 135. 2015-10-07. PMID:24907695. |
the purpose of this study was to measure the effects of daily intermittent caffeine exposure on lever pressing for sucrose in rats and to assess the impact of caffeine on neuronal activation in the nucleus accumbens (nac). |
2015-10-07 |
2023-08-13 |
rat |