All Relations between nucleus accumbens and nac

Publication Sentence Publish Date Extraction Date Species
X-X Peng, A Lister, A Rabinowitsch, R Kolaric, S Cabeza de Vaca, E B Ziff, K D Car. Episodic sucrose intake during food restriction increases synaptic abundance of AMPA receptors in nucleus accumbens and augments intake of sucrose following restoration of ad libitum feeding. Neuroscience. vol 295. 2016-01-13. PMID:25800309. based on findings that food restriction (fr) upregulates sucrose-induced trafficking of glutamatergic ampa receptors to the nucleus accumbens (nac) postsynaptic density (psd), this study was an initial test of the hypothesis that episodic "breakthrough" intake of forbidden food during dieting interacts with upregulated mechanisms of synaptic plasticity to increase reward-driven feeding. 2016-01-13 2023-08-13 human
Michael P Saddoris, Jonathan A Sugam, Garret D Stuber, Ilana B Witten, Karl Deisseroth, Regina M Carell. Mesolimbic dopamine dynamically tracks, and is causally linked to, discrete aspects of value-based decision making. Biological psychiatry. vol 77. issue 10. 2016-01-13. PMID:25541492. to make appropriate choices, organisms must weigh the costs and benefits of potential valuable outcomes, a process known to involve the nucleus accumbens (nac) and its dopaminergic input. 2016-01-13 2023-08-13 Not clear
Takashi Yamaguchi, Akihiro Goto, Ichiro Nakahara, Satoshi Yawata, Takatoshi Hikida, Michiyuki Matsuda, Kazuo Funabiki, Shigetada Nakanish. Role of PKA signaling in D2 receptor-expressing neurons in the core of the nucleus accumbens in aversive learning. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 36. 2016-01-06. PMID:26305972. the nucleus accumbens (nac) serves as a key neural substrate for aversive learning and consists of two distinct subpopulations of medium-sized spiny neurons (msns). 2016-01-06 2023-08-13 mouse
Romain Legrand, Nicolas Lucas, Jonathan Breton, Pierre Déchelotte, Sergueï O Fetisso. Dopamine release in the lateral hypothalamus is stimulated by α-MSH in both the anticipatory and consummatory phases of feeding. Psychoneuroendocrinology. vol 56. 2016-01-05. PMID:25805178. to address these questions, dynamics of dopamine release were measured in 15 min microdialysis samples simultaneously from the lha and the nucleus accumbens (nac) during consecutive exposure and provision of food and 1% sucrose in wistar rats after overnight food deprivation. 2016-01-05 2023-08-13 rat
Marta Peciña, Tiffany Love, Christian S Stohler, David Goldman, Jon-Kar Zubiet. Effects of the Mu opioid receptor polymorphism (OPRM1 A118G) on pain regulation, placebo effects and associated personality trait measures. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25308352. instead, aa homozygotes showed a blunted da response in the nucleus accumbens (nac) in response to the pain challenge. 2016-01-05 2023-08-13 human
Giordano de Guglielmo, Miriam Melis, Maria Antonietta De Luca, Marsida Kallupi, Hong Wu Li, Kevin Niswender, Antonio Giordano, Martina Senzacqua, Lorenzo Somaini, Andrea Cippitelli, George Gaitanaris, Gregory Demopulos, Ruslan Damadzic, Jenica Tapocik, Markus Heilig, Roberto Ciccociopp. PPARγ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25311134. these effects are associated with a marked reduction of heroin-induced increase in phosphorylation of darpp-32 protein in the nucleus accumbens (nac) and with a marked and selective reduction of acute heroin-induced elevation of extracellular dopamine (da) levels in the nac shell, as measured by in vivo microdialysis. 2016-01-05 2023-08-13 Not clear
Casey E O'Neill, Sophia C Levis, Drew C Schreiner, Jose Amat, Steven F Maier, Ryan K Bachtel. Effects of adolescent caffeine consumption on cocaine sensitivity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25328052. we identified the effects of adolescent caffeine consumption on cocaine sensitivity and determined neurobiological changes within the nucleus accumbens (nac) that may underlie caffeine-induced hypersensitivity to cocaine. 2016-01-05 2023-08-13 rat
Milad Mohammadi, Markus Fend. Relief learning is dependent on NMDA receptor activation in the nucleus accumbens. British journal of pharmacology. vol 172. issue 9. 2016-01-05. PMID:25572550. recently, we demonstrated that the nucleus accumbens (nac) is required for the acquisition and expression of relief memory. 2016-01-05 2023-08-13 Not clear
Xiusong Wang, Lei Liu, Wendy Adams, Shouxin Li, Qian Zhang, Bingjin Li, Min Wang, Ranji Cu. Cocaine exposure alters dopaminergic modulation of prefronto-accumbens transmission. Physiology & behavior. vol 145. 2016-01-04. PMID:25839095. in the nucleus accumbens (nac), dopamine transmission modulates glutamatergic input from the prefrontal cortex (pfc). 2016-01-04 2023-08-13 rat
Vasiliki Mitsi, Dimitra Terzi, Immanuel Purushothaman, Lefteris Manouras, Sevasti Gaspari, Rachael L Neve, Maria Stratinaki, Jian Feng, Li Shen, Venetia Zachario. RGS9-2--controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 36. 2016-01-04. PMID:26305935. here, we use the murine spared-nerve injury model of neuropathic pain to investigate the mechanism by which rgs9-2 in the nucleus accumbens (nac), a brain region involved in mood, reward, and motivation, modulates the actions of tricyclic antidepressants (tcas). 2016-01-04 2023-08-13 Not clear
Yan Li, Ruiming Zhu, Wenjing Wang, Dengqi Fu, Jing Hou, Sen Ji, Bo Chen, Zhengtao Hu, Xue Shao, Xuri Yu, Qian Zhao, Baolai Zhang, Changman Du, Qian Bu, Chunyan Hu, Yun Tang, Lei Zhong, Shengyong Yang, Yinglan Zhao, Xiaobo Ce. Arginine Methyltransferase 1 in the Nucleus Accumbens Regulates Behavioral Effects of Cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 37. 2016-01-04. PMID:26377474. here, we demonstrate that repeated noncontingent cocaine injections increase prmt1 activity in the nucleus accumbens (nac) of c57bl/6 mice. 2016-01-04 2023-08-13 mouse
Adeline Cathala, Céline Devroye, Marlène Maitre, Pier Vincenzo Piazza, Djoher Nora Abrous, Jean-Michel Revest, Umberto Spampinat. Serotonin2C receptors modulate dopamine transmission in the nucleus accumbens independently of dopamine release: behavioral, neurochemical and molecular studies with cocaine. Addiction biology. vol 20. issue 3. 2016-01-01. PMID:24661380. studies assessing the influence of 5-ht2c r agonists on cocaine-induced responses have suggested that 5-ht2c rs can modulate mesoaccumbens da pathway activity independently of accumbal da release, thereby controlling da transmission in the nucleus accumbens (nac). 2016-01-01 2023-08-12 Not clear
Zheng-Ming Ding, Cynthia M Ingraham, Zachary A Rodd, William J McBrid. The reinforcing effects of ethanol within the posterior ventral tegmental area depend on dopamine neurotransmission to forebrain cortico-limbic systems. Addiction biology. vol 20. issue 3. 2016-01-01. PMID:24674134. intra-pvta microinjection of ethanol increases dopamine release in the nucleus accumbens (nac), medial prefrontal cortex (mpfc) and ventral pallidum (vp). 2016-01-01 2023-08-12 Not clear
Su Xu, Rao P Gullapalli, Douglas O Fros. Olanzapine antipsychotic treatment of adolescent rats causes long term changes in glutamate and GABA levels in the nucleus accumbens. Schizophrenia research. vol 161. issue 2-3. 2015-12-31. PMID:25487700. we found that the treatment caused long-term reductions in the levels of both glu and gaba in the nucleus accumbens (nac) of adult rats treated with ola during adolescence. 2015-12-31 2023-08-13 rat
P A Pereira, M Vilela, S Sousa, J Neves, M M Paula-Barbosa, M D Madeir. Lesions of the laterodorsal tegmental nucleus alter the cholinergic innervation and neuropeptide Y expression in the medial prefrontal cortex and nucleus accumbens. Neuroscience. vol 284. 2015-12-30. PMID:25451286. the effects of this manipulation were determined in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) by estimating the numerical density of varicosities immunoreactive for vesicular acetylcholine transporter and the total number of nac neurons immunoreactive for choline acetyltransferase (chat) and neuropeptide y (npy) as well as the total number of mpfc neurons immunoreactive for npy and vasoactive intestinal polypeptide (vip). 2015-12-30 2023-08-13 rat
J T Yorgason, J H Rose, J M McIntosh, M J Ferris, S R Jone. Greater ethanol inhibition of presynaptic dopamine release in C57BL/6J than DBA/2J mice: Role of nicotinic acetylcholine receptors. Neuroscience. vol 284. 2015-12-30. PMID:25451295. the mesolimbic dopamine system, originating in the ventral tegmental area (vta) and projecting to the nucleus accumbens (nac), has been heavily implicated in the reinforcing effects of ethanol. 2015-12-30 2023-08-13 mouse
Bo Chen, Yao Wang, Xiaodong Liu, Zheng Liu, Yan Dong, Yanhua H Huan. Sleep Regulates Incubation of Cocaine Craving. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 39. 2015-12-28. PMID:26424879. incubation of cocaine craving is partially mediated by progressive accumulation of calcium-permeable ampa receptors (cp-ampars) in the nucleus accumbens (nac). 2015-12-28 2023-08-13 rat
Gislaine Z Réus, Marcos Paulo Nacif, Helena M Abelaira, Débora B Tomaz, Maria Augusta B dos Santos, Anelise S Carlessi, Beatriz I Matias, Jaine R da Luz, Amanda V Steckert, Gabriela C Jeremias, Giselli Scaini, Meline O S Morais, Emilio L Streck, João Queved. Ketamine treatment partly reverses alterations in brain derived- neurotrophic factor, oxidative stress and energy metabolism parameters induced by an animal model of depression. Current neurovascular research. vol 12. issue 1. 2015-12-28. PMID:25613382. in the amygdala, hippocampus and nucleus accumbens (nac), a reduction in bdnf levels was observed in deprived rats, but the animals treated with ketamine reversed the effects of this animal model only in the amygdala and nac. 2015-12-28 2023-08-13 rat
B ZióŁkowska, A Gieryk, W Solecki, R PrzewŁock. Temporal and anatomic patterns of immediate-early gene expression in the forebrain of C57BL/6 and DBA/2 mice after morphine administration. Neuroscience. vol 284. 2015-12-22. PMID:25290009. at 30 min, one or more iegs were induced in circumscribed subregions of the dorsal striatum (dstr) and of the nucleus accumbens (nac) shell, as well as in the lateral septum. 2015-12-22 2023-08-13 mouse
W Liu, F T Crew. Adolescent intermittent ethanol exposure enhances ethanol activation of the nucleus accumbens while blunting the prefrontal cortex responses in adult rat. Neuroscience. vol 293. 2015-12-15. PMID:25727639. binge drinking doses led to the nucleus accumbens (nac) activation that correlated with the ventral tegmental area (vta) activation. 2015-12-15 2023-08-13 rat