| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrey Finegersh, Carolyn Ferguson, Seth Maxwell, David Mazariegos, Daniel Farrell, Gregg E Homanic. Repeated vapor ethanol exposure induces transient histone modifications in the brain that are modified by genotype and brain region. Frontiers in molecular neuroscience. vol 8. 2015-08-24. PMID:26300722. |
we hypothesized that chronic intermittent etoh (cie) induces persistent changes in histone modifications across the cerebral cortex (ccx), nucleus accumbens (nac), and prefrontal cortex (pfc), and that these histone modifications are altered in a knock-in mouse strain with altered sensitivity to etoh. |
2015-08-24 |
2023-08-13 |
mouse |
| Julia Morud, Louise Adermark, Mia Ericson, Bo Söderpal. Alterations in ethanol-induced accumbal transmission after acute and long-term zinc depletion. Addiction biology. vol 20. issue 1. 2015-08-24. PMID:24102995. |
our findings show that the zn(2+) -chelating agent tricine slowly raises da levels when perfused in the nucleus accumbens (nac), whereas the more potent zn(2+) chelator tpen reduces da levels. |
2015-08-24 |
2023-08-12 |
human |
| Danielle C Malkusz, Ira Yenko, Francis M Rotella, Theodore Banakos, Kerstin Olsson, Trisha Dindyal, Vishal Vig, Richard J Bodna. Dopamine receptor signaling in the medial orbital frontal cortex and the acquisition and expression of fructose-conditioned flavor preferences in rats. Brain research. vol 1596. 2015-08-24. PMID:25446441. |
fructose-cfp expression was reduced following sch or rac in amy or nucleus accumbens (nac). |
2015-08-24 |
2023-08-13 |
rat |
| Rebecca Gregory, Hu Cheng, Heather A Rupp, Dale R Sengelaub, Julia R Heima. Oxytocin increases VTA activation to infant and sexual stimuli in nulliparous and postpartum women. Hormones and behavior. vol 69. 2015-08-24. PMID:25562711. |
because they have been shown to be associated with reward, the ventral tegmental area (vta) and nucleus accumbens (nac) were targeted as areas of expected alterations in activity. |
2015-08-24 |
2023-08-13 |
human |
| Renaud Massart, Royi Barnea, Yahav Dikshtein, Matthew Suderman, Oren Meir, Michael Hallett, Pamela Kennedy, Eric J Nestler, Moshe Szyf, Gal Yadi. Role of DNA methylation in the nucleus accumbens in incubation of cocaine craving. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 21. 2015-08-20. PMID:26019323. |
we show that the withdrawal periods, as well as cue-induced cocaine seeking, are associated with broad, time-dependent enhancement of dna methylation alterations in the nucleus accumbens (nac). |
2015-08-20 |
2023-08-13 |
rat |
| Achikam Haim, Morgan Sherer, Benedetta Leune. Gestational stress induces persistent depressive-like behavior and structural modifications within the postpartum nucleus accumbens. The European journal of neuroscience. vol 40. issue 12. 2015-08-20. PMID:25359225. |
here we examined the effects of gestational stress on depressive-like behavior during the early/mid and late postpartum periods and evaluated whether this was accompanied by altered structural plasticity in the nucleus accumbens (nac), a brain region that has been linked to ppd. |
2015-08-20 |
2023-08-13 |
rat |
| Lee Wei Lim, Marcus L F Janssen, Ersoy Kocabicak, Yasin Teme. The antidepressant effects of ventromedial prefrontal cortex stimulation is associated with neural activation in the medial part of the subthalamic nucleus. Behavioural brain research. vol 279. 2015-08-20. PMID:25446757. |
the nucleus accumbens (nac), ventromedial prefrontal cortex (vmpfc), and cingulate gyrus (cg) are key regions in the control of mood-related behaviors. |
2015-08-20 |
2023-08-13 |
Not clear |
| Ying Zhang, Hui Qu, You Zhou, Yi Wang, Duo Zhang, Xu Yang, ChunXiao Yang, ManYing X. The involvement of norepinephrine in pain modulation in the nucleus accumbens of morphine-dependent rats. Neuroscience letters. vol 585. 2015-08-19. PMID:25445369. |
in this study, we examined the role of ne on the evoked discharges of pain-excitation neurons (pens) and pain-inhibition neurons (pins) in the nucleus accumbens (nac) of rats, following the development of morphine dependence. |
2015-08-19 |
2023-08-13 |
rat |
| Margarita Arango-Lievano, Michael G Kaplit. [Depression and addiction comorbidity: towards a common molecular target?]. Medecine sciences : M/S. vol 31. issue 5. 2015-08-17. PMID:26059306. |
specifically, the limbic structures, such as the nucleus accumbens (nac), play a crucial role in both disorders. |
2015-08-17 |
2023-08-13 |
mouse |
| Jun Gao, Ning Zhu, Min Feng, Xiaolu Meng, Nan Su. Intra-nucleus-accumbens SKF38393 improved the impaired acquisition of morphine-conditioned place preference in depression-like rats. PsyCh journal. vol 1. issue 1. 2015-08-15. PMID:26272664. |
dopaminergic activity in the nucleus accumbens (nac) and the globus pallidus (gp) is important for the interaction between depression and addiction, with d1- and d2-like receptors playing different roles. |
2015-08-15 |
2023-08-13 |
rat |
| Xincai Ji, Sucharita Saha, Gilles E Marti. The origin of glutamatergic synaptic inputs controls synaptic plasticity and its modulation by alcohol in mice nucleus accumbens. Frontiers in synaptic neuroscience. vol 7. 2015-08-10. PMID:26257641. |
it is widely accepted that long-lasting changes of synaptic strength in the nucleus accumbens (nac), a brain region involved in drug reward, mediate acute and chronic effects of alcohol. |
2015-08-10 |
2023-08-13 |
mouse |
| Youngsun T Cho, Stephen Fromm, Amanda E Guyer, Allison Detloff, Daniel S Pine, Julie L Fudge, Monique Erns. Nucleus accumbens, thalamus and insula connectivity during incentive anticipation in typical adults and adolescents. NeuroImage. vol 66. 2015-08-06. PMID:23069809. |
studies of incentive processing have repeatedly demonstrated activation of nucleus accumbens (nac), thalamus, and anterior insula, three key components of reward neurocircuitry. |
2015-08-06 |
2023-08-12 |
Not clear |
| Betina González, Mariana Raineri, Jean Lud Cadet, Edgar García-Rill, Francisco J Urbano, Veronica Bisagn. Modafinil improves methamphetamine-induced object recognition deficits and restores prefrontal cortex ERK signaling in mice. Neuropharmacology. vol 87. 2015-08-04. PMID:24530829. |
we also measured extracellular signal-regulated kinase (erk) phosphorylation in medial prefrontal cortex (mpfc), hippocampus, and nucleus accumbens (nac) of meth- and vehicle-treated mice that received modafinil 1 h before exposure to novel objects in the training session, compared to mice placed in the arena without objects. |
2015-08-04 |
2023-08-12 |
mouse |
| Takuya Funayama, Yumiko Ikeda, Amane Tateno, Hidehiko Takahashi, Yoshiro Okubo, Haruhisa Fukayama, Hidenori Suzuk. Modafinil augments brain activation associated with reward anticipation in the nucleus accumbens. Psychopharmacology. vol 231. issue 16. 2015-08-04. PMID:24682502. |
the nucleus accumbens (nac) works as a key brain structure of the reward system, in which reward-related neural activity is well correlated with dopamine release from mesolimbic dopaminergic neurons. |
2015-08-04 |
2023-08-12 |
Not clear |
| Dimitra Terzi, Sevasti Gaspari, Lefteris Manouras, Giannina Descalzi, Vassiliki Mitsi, Venetia Zachario. RGS9-2 modulates sensory and mood related symptoms of neuropathic pain. Neurobiology of learning and memory. vol 115. 2015-08-04. PMID:25150149. |
our findings also reveal a temporal and regional regulation of rgs9-2 protein expression by neuropathic pain, as rgs9-2 levels are reduced in the spinal cord a few days after nerve injury, whereas decreased rgs9-2 levels in the nucleus accumbens (nac) are only observed several weeks after nerve injury. |
2015-08-04 |
2023-08-13 |
mouse |
| Veronica L Peterson, Brian A McCool, Derek A Hamilto. Effects of ethanol exposure and withdrawal on dendritic morphology and spine density in the nucleus accumbens core and shell. Brain research. vol 1594. 2015-08-04. PMID:25452024. |
structural alterations on medium spiny neurons (msns) of the nucleus accumbens (nac) have been observed following exposure to and withdrawal from a variety of drugs; however, relatively little is known about the effects of alcohol exposure and withdrawal on structural alterations of nac msns. |
2015-08-04 |
2023-08-13 |
rat |
| Ramesh Chandra, T Chase Francis, Prasad Konkalmatt, Ariunzaya Amgalan, Amy M Gancarz, David M Dietz, Mary Kay Lob. Opposing role for Egr3 in nucleus accumbens cell subtypes in cocaine action. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 20. 2015-08-03. PMID:25995477. |
an imbalance in molecular signaling cascades and transcriptional regulation in nucleus accumbens (nac) medium spiny neuron (msn) subtypes, those enriched in dopamine d1 versus d2 receptors, is implicated in the behavioral responses to psychostimulants. |
2015-08-03 |
2023-08-13 |
mouse |
| Jiamei Lian, Xu-Feng Huang, Nagesh Pai, Chao Den. Chronic betahistine co-treatment reverses olanzapine's effects on dopamine D₂ but not 5-HT2A/2C bindings in rat brains. Progress in neuro-psychopharmacology & biological psychiatry. vol 56. 2015-07-31. PMID:25149912. |
this study investigated the effects of chronic treatment of olanzapine and/or betahistine on the binding density of the serotonergic 5-ht2a (5-ht2ar) and 5-ht2c (5-ht2cr) receptors, 5-ht transporter (5-htt), and dopaminergic d₂ receptors (d₂r) in the brain regions involved in antipsychotic efficacy, including the prefrontal cortex (pfc), cingulate cortex (cg), nucleus accumbens (nac), and caudate putamen (cpu). |
2015-07-31 |
2023-08-13 |
rat |
| Mesbah Alam, Svilen Angelov, Meike Stemmler, Christof von Wrangel, Joachim K Krauss, Kerstin Schwab. Neuronal activity of the prefrontal cortex is reduced in rats selectively bred for deficient sensorimotor gating. Progress in neuro-psychopharmacology & biological psychiatry. vol 56. 2015-07-31. PMID:25220677. |
little is known about neuronal activity in the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), which are involved in the modulation of ppi. |
2015-07-31 |
2023-08-13 |
rat |
| Friedhelm C Schmitt, Juergen Voges, Hans-Jochen Heinze, Tino Zaehle, Martin Holtkamp, Alexander B Kowsk. Safety and feasibility of nucleus accumbens stimulation in five patients with epilepsy. Journal of neurology. vol 261. issue 8. 2015-07-28. PMID:24801491. |
in five adult patients with intractable partial epilepsy, safety and feasibility of chronic bilateral electrical stimulation of the nucleus accumbens (nac) were assessed, also providing initial indications of therapeutic efficacy. |
2015-07-28 |
2023-08-13 |
human |