| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jonathan M Ehrich, Paul E M Phillips, Charles Chavki. Kappa opioid receptor activation potentiates the cocaine-induced increase in evoked dopamine release recorded in vivo in the mouse nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 13. 2015-07-07. PMID:24971603. |
in this study, we used in vivo fast scan cyclic voltammetry to test the hypothesis that kor activation before cocaine administration might potentiate the evoked release of dopamine from ventral tegmental (vta) synaptic inputs to the nucleus accumbens (nac) and thereby increase the rewarding valence of cocaine. |
2015-07-07 |
2023-08-13 |
mouse |
| Joan Y Holgate, Selena E Bartlet. Early Life Stress, Nicotinic Acetylcholine Receptors and Alcohol Use Disorders. Brain sciences. vol 5. issue 3. 2015-07-03. PMID:26136145. |
emerging evidence suggests that neuroplastic changes in the nucleus accumbens (nac) following early life stress underlie the development of auds. |
2015-07-03 |
2023-08-13 |
Not clear |
| Daniel C Castro, Shannon L Cole, Kent C Berridg. Lateral hypothalamus, nucleus accumbens, and ventral pallidum roles in eating and hunger: interactions between homeostatic and reward circuitry. Frontiers in systems neuroscience. vol 9. 2015-06-30. PMID:26124708. |
the study of the neural bases of eating behavior, hunger, and reward has consistently implicated the lateral hypothalamus (lh) and its interactions with mesocorticolimbic circuitry, such as mesolimbic dopamine projections to nucleus accumbens (nac) and ventral pallidum (vp), in controlling motivation to eat. |
2015-06-30 |
2023-08-13 |
Not clear |
| Christa M Patterson, Jenny-Marie T Wong, Gina M Leinninger, Margaret B Allison, Omar S Mabrouk, Chelsea L Kasper, Ian E Gonzalez, Alexander Mackenzie, Justin C Jones, Robert T Kennedy, Martin G Myer. Ventral tegmental area neurotensin signaling links the lateral hypothalamus to locomotor activity and striatal dopamine efflux in male mice. Endocrinology. vol 156. issue 5. 2015-06-25. PMID:25734363. |
projections from the lateral hypothalamic area (lha) innervate components of the mesolimbic dopamine (mlda) system, including the ventral tegmental area (vta) and nucleus accumbens (nac), to modulate motivation appropriately for physiologic state. |
2015-06-25 |
2023-08-13 |
mouse |
| Mitsuhiro Edamura, Gen Murakami, Hongrui Meng, Makoto Itakura, Ryuichi Shigemoto, Atsuo Fukuda, Daiichiro Nakahar. Functional deficiency of MHC class I enhances LTP and abolishes LTD in the nucleus accumbens of mice. PloS one. vol 9. issue 9. 2015-06-25. PMID:25268136. |
these molecules are expressed in various brain areas, especially in regions undergoing activity-dependent synaptic plasticity, but their role in the nucleus accumbens (nac) is unknown. |
2015-06-25 |
2023-08-13 |
mouse |
| Sara E Berger, Alexis T Baria, Marwan N Baliki, Ali Mansour, Kristi M Herrmann, Souraya Torbey, Lejian Huang, Elle L Parks, Thomas J Schnizter, A Vania Apkaria. Risky monetary behavior in chronic back pain is associated with altered modular connectivity of the nucleus accumbens. BMC research notes. vol 7. 2015-06-25. PMID:25331931. |
the nucleus accumbens (nac) has a well established role in reward processing. |
2015-06-25 |
2023-08-13 |
human |
| Michelle Lee, Toby R Manders, Sarah E Eberle, Chen Su, James D'amour, Runtao Yang, Hau Yueh Lin, Karl Deisseroth, Robert C Froemke, Jing Wan. Activation of corticostriatal circuitry relieves chronic neuropathic pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 13. 2015-06-19. PMID:25834050. |
a key output target for the pfc is the nucleus accumbens (nac), an important component of the reward circuitry. |
2015-06-19 |
2023-08-13 |
human |
| Cody A Siciliano, Erin S Calipari, Verginia C Cuzon Carlson, Christa M Helms, David M Lovinger, Kathleen A Grant, Sara R Jone. Voluntary ethanol intake predicts κ-opioid receptor supersensitivity and regionally distinct dopaminergic adaptations in macaques. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 15. 2015-06-18. PMID:25878269. |
here we examine the effects of chronic voluntary ethanol self-administration on dopamine neurotransmission and the ability of kors to regulate dopamine release in the dorsolateral caudate (dlc) and nucleus accumbens (nac) core. |
2015-06-18 |
2023-08-13 |
Not clear |
| Ja Wook Koo, Mary Kay Lobo, Dipesh Chaudhury, Benoit Labonté, Allyson Friedman, Elizabeth Heller, Catherine Jensen Peña, Ming-Hu Han, Eric J Nestle. Loss of BDNF signaling in D1R-expressing NAc neurons enhances morphine reward by reducing GABA inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 11. 2015-06-15. PMID:24853771. |
the nucleus accumbens (nac) has a central role in the mechanism of action of drugs of abuse. |
2015-06-15 |
2023-08-13 |
mouse |
| Jian Feng, Ningyi Shao, Keith E Szulwach, Vincent Vialou, Jimmy Huynh, Chun Zhong, Thuc Le, Deveroux Ferguson, Michael E Cahill, Yujing Li, Ja Wook Koo, Efrain Ribeiro, Benoit Labonte, Benjamin M Laitman, David Estey, Victoria Stockman, Pamela Kennedy, Thomas Couroussé, Isaac Mensah, Gustavo Turecki, Kym F Faull, Guo-li Ming, Hongjun Song, Guoping Fan, Patrizia Casaccia, Li Shen, Peng Jin, Eric J Nestle. Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nature neuroscience. vol 18. issue 4. 2015-06-08. PMID:25774451. |
we found that ten-eleven translocation protein 1 (tet1) was downregulated in mouse nucleus accumbens (nac), a key brain reward structure, by repeated cocaine administration, which enhanced behavioral responses to cocaine. |
2015-06-08 |
2023-08-13 |
mouse |
| Z M Jeanes, T R Buske, R A Morriset. Cell type-specific synaptic encoding of ethanol exposure in the nucleus accumbens shell. Neuroscience. vol 277. 2015-06-08. PMID:25003712. |
synaptic alterations in the nucleus accumbens (nac) are crucial for the aberrant reward-associated learning that forms the foundation of drug dependence. |
2015-06-08 |
2023-08-13 |
mouse |
| G-Q Chang, O Karatayev, J R Barson, S C Liang, S F Leibowit. Common effects of fat, ethanol, and nicotine on enkephalin in discrete areas of the brain. Neuroscience. vol 277. 2015-06-08. PMID:25086310. |
to test whether these substances act similarly on the same neuronal populations in specific brain areas mediating these behaviors, we administered the substances short-term, using the same methods and within the same experiment, and measured their effects, in areas of the hypothalamus (hypo), amygdala (amyg), and nucleus accumbens (nac), on mrna levels of the opioid peptide, enkephalin (enk), using in situ hybridization and on c-fos immunoreactivity (ir) to indicate neuronal activity, using immunofluorescence histochemistry. |
2015-06-08 |
2023-08-13 |
rat |
| Domenic H Cerri, Michael P Saddoris, Regina M Carell. Nucleus accumbens core neurons encode value-independent associations necessary for sensory preconditioning. Behavioral neuroscience. vol 128. issue 5. 2015-06-04. PMID:25244086. |
at the neural level, the nucleus accumbens (nac) is known to encode associative information, but it is not known whether this encoding is specific for value-based information (consistent with reinforcement-based models) or if the nac additionally plays a more general role in forming predictive associations, independent of outcome value. |
2015-06-04 |
2023-08-13 |
rat |
| Cecilia Nauczyciel, Suzanne Robic, Thibaut Dondaine, Marc Verin, Gabriel Robert, Dominique Drapier, Florian Naudet, Bruno Mille. The nucleus accumbens: a target for deep brain stimulation in resistant major depressive disorder. Journal of molecular psychiatry. vol 1. 2015-05-28. PMID:26019865. |
we explored the role of nucleus accumbens (nac) as a target for treatment. |
2015-05-28 |
2023-08-13 |
Not clear |
| Praneeth Namburi, Anna Beyeler, Suzuko Yorozu, Gwendolyn G Calhoon, Sarah A Halbert, Romy Wichmann, Stephanie S Holden, Kim L Mertens, Melodi Anahtar, Ada C Felix-Ortiz, Ian R Wickersham, Jesse M Gray, Kay M Ty. A circuit mechanism for differentiating positive and negative associations. Nature. vol 520. issue 7549. 2015-05-27. PMID:25925480. |
here we show that bla neurons projecting to the nucleus accumbens (nac projectors) or the centromedial amygdala (cem projectors) undergo opposing synaptic changes following fear or reward conditioning. |
2015-05-27 |
2023-08-13 |
Not clear |
| Collin J Kreple, Yuan Lu, Ryan T LaLumiere, John A Wemmi. Drug abuse and the simplest neurotransmitter. ACS chemical neuroscience. vol 5. issue 9. 2015-05-26. PMID:25054738. |
now, recent experiments provide some of the strongest support to date that protons function as a neurotransmitter in mice, crossing synapses onto medium spiny neurons of the nucleus accumbens (nac), activating asics, and ultimately suppressing drug abuse-related behaviors. |
2015-05-26 |
2023-08-13 |
mouse |
| Jun-Jun Wang, Wen-Qing Yao, Yue-Jun Chen, Lan Ma, Ye-Zheng Ta. [Neurons in NAc core and BLA are activated during cocaine context-associated reward memory retrieval in mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 66. issue 5. 2015-05-16. PMID:25332000. |
the results showed that: neuronal c-fos, zif268 protein expression levels in nucleus accumbens (nac) core both were elevated in cocaine retrieval group compared with those in saline retrieval (control) group during cocaine context-associated reward memory retrieval. |
2015-05-16 |
2023-08-13 |
mouse |
| John M Burkhardt, Louise Adermar. Locus of onset and subpopulation specificity of in vivo ethanol effect in the reciprocal ventral tegmental area-nucleus accumbens circuit. Neurochemistry international. vol 76. 2015-05-15. PMID:25058792. |
elevated levels of dopamine in the nucleus accumbens (nac) as a consequence of increased activation of dopaminergic neurons in the vta are associated with the reinforcing properties of ethanol consumption, but whether the initiation of drug-response is connected to a direct activation of dopaminergic cell bodies in the vta region or involves gabaergic neurons in vta and/or the nac is unclear. |
2015-05-15 |
2023-08-13 |
mouse |
| James E McCutcheon, Jackson J Cone, Christopher G Sinon, Samantha M Fortin, Pranish A Kantak, Ilana B Witten, Karl Deisseroth, Garret D Stuber, Mitchell F Roitma. Optical suppression of drug-evoked phasic dopamine release. Frontiers in neural circuits. vol 8. 2015-05-15. PMID:25278845. |
here, we used in vivo fast-scan cyclic voltammetry to record transients evoked by cocaine and raclopride in nucleus accumbens (nac) of urethane-anesthetized rats. |
2015-05-15 |
2023-08-13 |
rat |
| Mario Marchi, Massimo Grilli, Anna M Pittalug. Nicotinic modulation of glutamate receptor function at nerve terminal level: a fine-tuning of synaptic signals. Frontiers in pharmacology. vol 6. 2015-05-14. PMID:25972809. |
indeed, in the rat nucleus accumbens (nac), the function of some ampa and nmda receptors present on the dopaminergic and glutamatergic nerve terminals can be regulated negatively or positively in response to a brief activation of nachrs. |
2015-05-14 |
2023-08-13 |
rat |