| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H J Lee, J M Youn, M Gallagher, P C Hollan. Temporally limited role of substantia nigra-central amygdala connections in surprise-induced enhancement of learning. The European journal of neuroscience. vol 27. issue 11. 2008-08-20. PMID:18588542. |
we recently showed that midbrain dopamine neurons, known to code prediction error, are also important for surprise-induced enhancement of learning through their interaction with cea. |
2008-08-20 |
2023-08-12 |
rat |
| J G P Ferreira, F Del-Fava, R H Hasue, S J Shammah-Lagnad. Organization of ventral tegmental area projections to the ventral tegmental area-nigral complex in the rat. Neuroscience. vol 153. issue 1. 2008-08-18. PMID:18358616. |
based on its striatal output, it has been subdivided in a caudomedial part which targets the ventromedial striatum, and a lateral part which targets the ventrolateral striatum [ikemoto s (2007) dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. |
2008-08-18 |
2023-08-12 |
rat |
| R G Nair-Roberts, S D Chatelain-Badie, E Benson, H White-Cooper, J P Bolam, M A Ungles. Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat. Neuroscience. vol 152. issue 4. 2008-08-07. PMID:18355970. |
midbrain dopamine neurons in the ventral tegmental area, substantia nigra and retrorubral field play key roles in reward processing, learning and memory, and movement. |
2008-08-07 |
2023-08-12 |
rat |
| R G Nair-Roberts, S D Chatelain-Badie, E Benson, H White-Cooper, J P Bolam, M A Ungles. Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat. Neuroscience. vol 152. issue 4. 2008-08-07. PMID:18355970. |
within these midbrain regions and admixed with the dopamine neurons, are also substantial populations of gabaergic neurons that regulate dopamine neuron activity and have projection targets similar to those of dopamine neurons. |
2008-08-07 |
2023-08-12 |
rat |
| R G Nair-Roberts, S D Chatelain-Badie, E Benson, H White-Cooper, J P Bolam, M A Ungles. Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat. Neuroscience. vol 152. issue 4. 2008-08-07. PMID:18355970. |
these results demonstrate that gabaergic and glutamatergic neurons represent large proportions of the neurons in what are traditionally considered as dopamine nuclei and that there are considerable heterogeneities in the proportions of cell types in the different dopaminergic midbrain regions. |
2008-08-07 |
2023-08-12 |
rat |
| Eva Hedlund, Jan Pruszak, Thomas Lardaro, Wesley Ludwig, Angel Viñuela, Kwang-Soo Kim, Ole Isacso. Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease. Stem cells (Dayton, Ohio). vol 26. issue 6. 2008-08-06. PMID:18388307. |
embryonic stem cell-derived pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of parkinson's disease. |
2008-08-06 |
2023-08-12 |
mouse |
| Eva Hedlund, Jan Pruszak, Thomas Lardaro, Wesley Ludwig, Angel Viñuela, Kwang-Soo Kim, Ole Isacso. Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease. Stem cells (Dayton, Ohio). vol 26. issue 6. 2008-08-06. PMID:18388307. |
toward this goal, we used a pitx3-enhanced green fluorescent protein (pitx3-egfp) knock-in mouse blastocyst-derived embryonic stem (mes) cell line and fluorescence-activated cell sorting (facs) to select and purify midbrain dopamine neurons. |
2008-08-06 |
2023-08-12 |
mouse |
| Eva Hedlund, Jan Pruszak, Thomas Lardaro, Wesley Ludwig, Angel Viñuela, Kwang-Soo Kim, Ole Isacso. Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease. Stem cells (Dayton, Ohio). vol 26. issue 6. 2008-08-06. PMID:18388307. |
egfp expression overlapped closely with that of pitx3, nurr1, engrailed-1, lmx1a, tyrosine hydroxylase (th), l-aromatic amino acid decarboxylase (aadc), and vesicular monoamine transporter 2 (vmat2), demonstrating that these cells were of a midbrain dopamine neuron character. |
2008-08-06 |
2023-08-12 |
mouse |
| Eva Hedlund, Jan Pruszak, Thomas Lardaro, Wesley Ludwig, Angel Viñuela, Kwang-Soo Kim, Ole Isacso. Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease. Stem cells (Dayton, Ohio). vol 26. issue 6. 2008-08-06. PMID:18388307. |
transplantation to 6-hydroxydopamine-lesioned rats showed that an enriched dopaminergic population could survive and restore both amphetamine- and apomorphine-induced functions, and the grafts contained large numbers of midbrain dopamine neurons, which innervated the host striatum. |
2008-08-06 |
2023-08-12 |
mouse |
| Samuel D Gale, Abigail L Person, David J Perke. A novel basal ganglia pathway forms a loop linking a vocal learning circuit with its dopaminergic input. The Journal of comparative neurology. vol 508. issue 5. 2008-08-01. PMID:18398824. |
neurons in midbrain dopamine centers, the substantia nigra pars compacta (snc) and ventral tegmental area (vta), densely innervate area x and show singing-related changes in firing rate. |
2008-08-01 |
2023-08-12 |
Not clear |
| Karen E Murphy, Tanya Karaconji, Craig D Hardman, Glenda M Hallida. Excessive dopamine neuron loss in progressive supranuclear palsy. Movement disorders : official journal of the Movement Disorder Society. vol 23. issue 4. 2008-07-22. PMID:18163454. |
we observed more widespread dopamine neuron loss in the extranigral a10 midbrain cell groups in psp compared with pd. |
2008-07-22 |
2023-08-12 |
Not clear |
| J C Lewers, I Ceballos-Picot, T L Shirley, L Mockel, K Egami, H A Jinna. Consequences of impaired purine recycling in dopaminergic neurons. Neuroscience. vol 152. issue 3. 2008-07-21. PMID:18313225. |
a unique sensitivity to specific biochemical processes is responsible for selective vulnerability of midbrain dopamine neurons in several diseases. |
2008-07-21 |
2023-08-12 |
mouse |
| Ivar Mendez, Angel Viñuela, Arnar Astradsson, Karim Mukhida, Penelope Hallett, Harold Robertson, Travis Tierney, Renn Holness, Alain Dagher, John Q Trojanowski, Ole Isacso. Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years. Nature medicine. vol 14. issue 5. 2008-07-17. PMID:18391961. |
postmortem analysis of five subjects with parkinson's disease 9-14 years after transplantation of fetal midbrain cell suspensions revealed surviving grafts that included dopamine and serotonin neurons without pathology. |
2008-07-17 |
2023-08-12 |
human |
| Ivar Mendez, Angel Viñuela, Arnar Astradsson, Karim Mukhida, Penelope Hallett, Harold Robertson, Travis Tierney, Renn Holness, Alain Dagher, John Q Trojanowski, Ole Isacso. Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years. Nature medicine. vol 14. issue 5. 2008-07-17. PMID:18391961. |
these findings are important for the understanding of the etiopathogenesis of midbrain dopamine neuron degeneration and future use of cell replacement therapies. |
2008-07-17 |
2023-08-12 |
human |
| Tatiana Rojkovicova, Yehia Mechref, Jason A Starkey, Guangxiang Wu, Richard L Bell, William J McBride, Milos V Novotn. Quantitative chiral analysis of salsolinol in different brain regions of rats genetically predisposed to alcoholism. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 863. issue 2. 2008-07-10. PMID:18272438. |
a method to determine the catecholamine content in putamen (cpu) and midbrain (mb) regions of the brain of alcohol-preferring rats (p) is presented with a focus on the low-level detection of s,r-salsolinol, a metabolite of dopamine and a putative alcoholism marker. |
2008-07-10 |
2023-08-12 |
rat |
| Shin Hye Kim, Yu Mi Choi, Jin Yong Jang, Sungkwon Chung, Yun Kyung Kang, Myoung Kyu Par. Nonselective cation channels are essential for maintaining intracellular Ca2+ levels and spontaneous firing activity in the midbrain dopamine neurons. Pflugers Archiv : European journal of physiology. vol 455. issue 2. 2008-06-30. PMID:17492308. |
nonselective cation channels are essential for maintaining intracellular ca2+ levels and spontaneous firing activity in the midbrain dopamine neurons. |
2008-06-30 |
2023-08-12 |
rat |
| Shin Hye Kim, Yu Mi Choi, Jin Yong Jang, Sungkwon Chung, Yun Kyung Kang, Myoung Kyu Par. Nonselective cation channels are essential for maintaining intracellular Ca2+ levels and spontaneous firing activity in the midbrain dopamine neurons. Pflugers Archiv : European journal of physiology. vol 455. issue 2. 2008-06-30. PMID:17492308. |
intracellular ca2+ and ca2+-permeable ion channels are important in regulating the firing activity and pattern of midbrain dopamine neurons, but the role of ca2+-permeable nonselective cation channels (nsccs) on spontaneous firing activity is unclear. |
2008-06-30 |
2023-08-12 |
rat |
| Shin Hye Kim, Yu Mi Choi, Jin Yong Jang, Sungkwon Chung, Yun Kyung Kang, Myoung Kyu Par. Nonselective cation channels are essential for maintaining intracellular Ca2+ levels and spontaneous firing activity in the midbrain dopamine neurons. Pflugers Archiv : European journal of physiology. vol 455. issue 2. 2008-06-30. PMID:17492308. |
therefore, we investigated how ca2+-permeable nsccs modulate spontaneous firing activity and cytosolic ca2+ concentration ([ca2+]c) in acutely isolated midbrain dopamine neurons of the rat. |
2008-06-30 |
2023-08-12 |
rat |
| Shin Hye Kim, Yu Mi Choi, Jin Yong Jang, Sungkwon Chung, Yun Kyung Kang, Myoung Kyu Par. Nonselective cation channels are essential for maintaining intracellular Ca2+ levels and spontaneous firing activity in the midbrain dopamine neurons. Pflugers Archiv : European journal of physiology. vol 455. issue 2. 2008-06-30. PMID:17492308. |
from these data, we conclude that nsccs not only make up the tonic ca2+ entry pathways to uphold basal [ca2+]c levels but also contribute to generation of spontaneous firings, thereby regulating spontaneous firing activities of the midbrain dopamine neurons. |
2008-06-30 |
2023-08-12 |
rat |
| Sutapa Das, Debjani Guh. CNS depressive role of aqueous extract of Spinacia oleracea L. leaves in adult male albino rats. Indian journal of experimental biology. vol 46. issue 3. 2008-06-17. PMID:18432058. |
so increased serotonin level and decreased both norepinephrine and dopamine levels in cerebral cortex, cerebellum, caudate nucleus, midbrain and pons and medulla. |
2008-06-17 |
2023-08-12 |
rat |