| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Inmaculada Tasset, Ismael Quero, Ángel D García-Mayórgaz, Manuel Causse del Río, Isaac Túnez, Pedro Montill. Changes caused by haloperidol are blocked by music in Wistar rat. Journal of physiology and biochemistry. vol 68. issue 2. 2012-08-30. PMID:22371013. |
the results obtained here bear out reports that music triggers a reduction in systolic pressure and an increase in mesencephalon dopamine levels in human and rats treated with ecstasy, through a calmodulin-dependent system. |
2012-08-30 |
2023-08-12 |
human |
| Jeong Won Jahng, Sang Bae Yoo, Jin Young Kim, Bom-Taeck Kim, Jong-Ho Le. Increased mesohippocampal dopaminergic activity and improved depression-like behaviors in maternally separated rats following repeated fasting/refeeding cycles. Journal of obesity. vol 2012. 2012-08-30. PMID:22934157. |
fasting/refeeding cycles increased dopamine levels not only in the hippocampus but also in the midbrain dopaminergic neurons in ms rats, but not in nh controls. |
2012-08-30 |
2023-08-12 |
rat |
| Mikko Airavaara, Merja H Voutilainen, Yun Wang, Barry Hoffe. Neurorestoration. Parkinsonism & related disorders. vol 18 Suppl 1. 2012-08-27. PMID:22166416. |
although initially thought to be important primarily in neural development, a number of trophic proteins have been found to have neuroprotective and neuroregenerative activity in the adult central nervous system, particularly for midbrain dopamine neurons (mdn). |
2012-08-27 |
2023-08-12 |
Not clear |
| Dawn Béraud, Kathleen A Maguire-Zeis. Misfolded α-synuclein and Toll-like receptors: therapeutic targets for Parkinson's disease. Parkinsonism & related disorders. vol 18 Suppl 1. 2012-08-27. PMID:22166424. |
parkinson's disease (pd) is typified by the loss of midbrain dopamine neurons, the presence of large proteinaceous α-synuclein-positive intracellular inclusions, oxidatively modified molecules and activated microglia. |
2012-08-27 |
2023-08-12 |
Not clear |
| Margaret Chia-Ying Wey, Elizabeth Fernandez, Paul Anthony Martinez, Patricia Sullivan, David S Goldstein, Randy Stron. Neurodegeneration and motor dysfunction in mice lacking cytosolic and mitochondrial aldehyde dehydrogenases: implications for Parkinson's disease. PloS one. vol 7. issue 2. 2012-08-27. PMID:22384032. |
reduced aldh1 expression in surviving midbrain dopamine neurons has been reported in brains of patients who died with pd. |
2012-08-27 |
2023-08-12 |
mouse |
| Uhnoh Kim, Taehee Le. Topography of descending projections from anterior insular and medial prefrontal regions to the lateral habenula of the epithalamus in the rat. The European journal of neuroscience. vol 35. issue 8. 2012-08-27. PMID:22512256. |
the epithalamic lateral nucleus of the habenula (lhb) plays a key role in regulating firing of dopamine and serotonin neurons in the midbrain and is thereby involved in various cognitive and affective behaviors. |
2012-08-27 |
2023-08-12 |
rat |
| Mitsuko Watabe-Uchida, Lisa Zhu, Sachie K Ogawa, Archana Vamanrao, Naoshige Uchid. Whole-brain mapping of direct inputs to midbrain dopamine neurons. Neuron. vol 74. issue 5. 2012-08-17. PMID:22681690. |
whole-brain mapping of direct inputs to midbrain dopamine neurons. |
2012-08-17 |
2023-08-12 |
Not clear |
| Jeffrey M Zacks, Christopher A Kurby, Michelle L Eisenberg, Nayiri Haroutunia. Prediction error associated with the perceptual segmentation of naturalistic events. Journal of cognitive neuroscience. vol 23. issue 12. 2012-08-13. PMID:21671745. |
at points of unpredictability, midbrain and striatal regions associated with the phasic release of the neurotransmitter dopamine transiently increased in activity. |
2012-08-13 |
2023-08-12 |
Not clear |
| Julia P Dunn, Robert M Kessler, Irene D Feurer, Nora D Volkow, Bruce W Patterson, Mohammad S Ansari, Rui Li, Pamela Marks-Shulman, Naji N Abumra. Relationship of dopamine type 2 receptor binding potential with fasting neuroendocrine hormones and insulin sensitivity in human obesity. Diabetes care. vol 35. issue 5. 2012-08-09. PMID:22432117. |
midbrain dopamine (da) neurons, which are involved with reward and motivation, are modulated by hormones that regulate food intake (insulin, leptin, and acyl ghrelin [ag]). |
2012-08-09 |
2023-08-12 |
human |
| Christopher R Bye, Lachlan H Thompson, Clare L Paris. Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into parkinsonian mice. Experimental neurology. vol 236. issue 1. 2012-08-07. PMID:22524988. |
birth dating of midbrain dopamine neurons identifies a9 enriched tissue for transplantation into parkinsonian mice. |
2012-08-07 |
2023-08-12 |
mouse |
| Christopher R Bye, Lachlan H Thompson, Clare L Paris. Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into parkinsonian mice. Experimental neurology. vol 236. issue 1. 2012-08-07. PMID:22524988. |
clinical trials have provided proof of principle that new dopamine neurons isolated from the developing ventral midbrain and transplanted into the denervated striatum can functionally integrate and alleviate symptoms in parkinson's disease patients. |
2012-08-07 |
2023-08-12 |
mouse |
| Christopher R Bye, Lachlan H Thompson, Clare L Paris. Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into parkinsonian mice. Experimental neurology. vol 236. issue 1. 2012-08-07. PMID:22524988. |
dissections of ventral midbrain used for transplantation will variously contain progenitors for different dopamine neuron subtypes as well as different neurotransmitter phenotypes. |
2012-08-07 |
2023-08-12 |
mouse |
| Christopher R Bye, Lachlan H Thompson, Clare L Paris. Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into parkinsonian mice. Experimental neurology. vol 236. issue 1. 2012-08-07. PMID:22524988. |
here we performed a birth dating study to identify the time-course of neurogenesis within the various ventral midbrain dopamine subpopulations in an effort to identify a9-enriched donor tissue for transplantation. |
2012-08-07 |
2023-08-12 |
mouse |
| Christopher R Bye, Lachlan H Thompson, Clare L Paris. Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into parkinsonian mice. Experimental neurology. vol 236. issue 1. 2012-08-07. PMID:22524988. |
subsequent grafting of younger ventral midbrain donor tissue revealed significantly larger grafts containing more mitotic dopamine neuroblasts compared to older donor grafts. |
2012-08-07 |
2023-08-12 |
mouse |
| Lauren G Friedman, M Lenard Lachenmayer, Jing Wang, Liqiang He, Shibu M Poulose, Masaaki Komatsu, Gay R Holstein, Zhenyu Yu. Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 22. 2012-08-06. PMID:22649237. |
parkinson's disease (pd) is characterized pathologically by the formation of ubiquitin and α-synuclein (α-syn)-containing inclusions (lewy bodies), dystrophic dopamine (da) terminals, and degeneration of midbrain da neurons. |
2012-08-06 |
2023-08-12 |
mouse |
| Lauren G Friedman, M Lenard Lachenmayer, Jing Wang, Liqiang He, Shibu M Poulose, Masaaki Komatsu, Gay R Holstein, Zhenyu Yu. Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 22. 2012-08-06. PMID:22649237. |
in contrast, atg7-deficient da neurons in the midbrain exhibit early dendritic and axonal dystrophy, reduced striatal dopamine content, and the formation of somatic and dendritic ubiquitinated inclusions in da neurons. |
2012-08-06 |
2023-08-12 |
mouse |
| Yukio Ago, Toshiyuki Kawasaki, Tetsuaki Nashida, Yuki Ota, Yana Cong, Mari Kitamoto, Teisuke Takahashi, Kazuhiro Takuma, Toshio Matsud. SEA0400, a specific Na+/Ca2+ exchange inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease. Neuropharmacology. vol 61. issue 8. 2012-08-01. PMID:21903118. |
mptp treatment (10 mg/kg, four times at 2-h intervals) decreased dopamine levels in the midbrain and impaired motor coordination, and these effects were counteracted by s-methylthiocitrulline, a selective neuronal no synthase inhibitor. |
2012-08-01 |
2023-08-12 |
mouse |
| Yukio Ago, Toshiyuki Kawasaki, Tetsuaki Nashida, Yuki Ota, Yana Cong, Mari Kitamoto, Teisuke Takahashi, Kazuhiro Takuma, Toshio Matsud. SEA0400, a specific Na+/Ca2+ exchange inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease. Neuropharmacology. vol 61. issue 8. 2012-08-01. PMID:21903118. |
sea0400 protected against the dopaminergic neurotoxicity (determined by dopamine levels in the midbrain and striatum, tyrosine hydroxylase immunoreactivity in the substantia nigra and striatum, striatal dopamine release, and motor deficits) in mptp-treated mice. |
2012-08-01 |
2023-08-12 |
mouse |
| Julianna Kele, Emma R Andersson, J Carlos Villaescusa, Lukas Cajanek, Clare L Parish, Sonia Bonilla, Enrique M Toledo, Vitezslav Bryja, Jeffrey S Rubin, Akihiko Shimono, Ernest Arena. SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells. Stem cells (Dayton, Ohio). vol 30. issue 5. 2012-07-30. PMID:22290867. |
sfrp1 and sfrp2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells. |
2012-07-30 |
2023-08-12 |
mouse |
| Julianna Kele, Emma R Andersson, J Carlos Villaescusa, Lukas Cajanek, Clare L Parish, Sonia Bonilla, Enrique M Toledo, Vitezslav Bryja, Jeffrey S Rubin, Akihiko Shimono, Ernest Arena. SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells. Stem cells (Dayton, Ohio). vol 30. issue 5. 2012-07-30. PMID:22290867. |
secreted frizzled related proteins (sfrps) are a family of proteins that modulate wnt signaling, which in turn regulates multiple aspects of ventral midbrain (vm) and dopamine (da) neuron development. |
2012-07-30 |
2023-08-12 |
mouse |