| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eileen Maria Joyc. Organic psychosis: The pathobiology and treatment of delusions. CNS neuroscience & therapeutics. vol 24. issue 7. 2019-06-10. PMID:29766653. |
the conclusion of these studies is that the right lateral prefrontal cortex is 1 hub in a neural network which includes the basal ganglia and limbic system and receives inputs from midbrain dopamine neurones. |
2019-06-10 |
2023-08-13 |
Not clear |
| Angel Martin-de-Pablos, Antonio Córdoba-Fernández, Emilio Fernández-Espej. Analysis of neurotrophic and antioxidant factors related to midbrain dopamine neuronal loss and brain inflammation in the cerebrospinal fluid of the elderly. Experimental gerontology. vol 110. 2019-06-03. PMID:29775745. |
analysis of neurotrophic and antioxidant factors related to midbrain dopamine neuronal loss and brain inflammation in the cerebrospinal fluid of the elderly. |
2019-06-03 |
2023-08-13 |
human |
| Angel Martin-de-Pablos, Antonio Córdoba-Fernández, Emilio Fernández-Espej. Analysis of neurotrophic and antioxidant factors related to midbrain dopamine neuronal loss and brain inflammation in the cerebrospinal fluid of the elderly. Experimental gerontology. vol 110. 2019-06-03. PMID:29775745. |
midbrain dopamine neuronal loss and neuroinflammation are two phenomena that are associated with brain senescence. |
2019-06-03 |
2023-08-13 |
human |
| Angel Martin-de-Pablos, Antonio Córdoba-Fernández, Emilio Fernández-Espej. Analysis of neurotrophic and antioxidant factors related to midbrain dopamine neuronal loss and brain inflammation in the cerebrospinal fluid of the elderly. Experimental gerontology. vol 110. 2019-06-03. PMID:29775745. |
the objective was to analyze neurotrophic and oxidative parameters that could be related to midbrain dopamine neuronal loss or brain inflammation in the csf of elderly subjects: 1) levels of the dopaminotrophic factors bdnf, gdnf, persephin, and neurturin, 2) levels of the proinflammatory factors tgfβ |
2019-06-03 |
2023-08-13 |
human |
| Gemma Modinos, Alice Egerton, Katrina McMullen, Anna McLaughlin, Veena Kumari, Gareth J Barker, Steve C R Williams, Fernando Zelay. Increased resting perfusion of the hippocampus in high positive schizotypy: A pseudocontinuous arterial spin labeling study. Human brain mapping. vol 39. issue 10. 2019-06-03. PMID:29885018. |
based on preclinical evidence that hippocampal hyperactivity leads to increased activity in mesostriatal dopamine projections, cbf in hippocampus, midbrain, and striatum was assessed. |
2019-06-03 |
2023-08-13 |
human |
| Nadia Giordano, Attilio Iemolo, Maria Mancini, Fabrizio Cacace, Maria De Risi, Emanuele Claudio Latagliata, Veronica Ghiglieri, Gian Carlo Bellenchi, Stefano Puglisi-Allegra, Paolo Calabresi, Barbara Picconi, Elvira De Leonibu. Motor learning and metaplasticity in striatal neurons: relevance for Parkinson's disease. Brain : a journal of neurology. vol 141. issue 2. 2019-05-30. PMID:29281030. |
we then assessed how this process is modulated by dopamine receptors and the dopamine active transporter, and whether it is impaired by overexpression of human α-synuclein in the mesencephalon; the latter is a progressive animal model of parkinson's disease. |
2019-05-30 |
2023-08-13 |
human |
| Shannon M Saszik, Conor M Smit. The impact of stress on social behavior in adult zebrafish (Danio rerio). Behavioural pharmacology. vol 29. issue 1. 2019-05-28. PMID:28926343. |
stress has adverse effects on social behavior that is mediated by dopamine circuits in the midbrain. |
2019-05-28 |
2023-08-13 |
zebrafish |
| Rachel J Smith, Peter J Vento, Ying S Chao, Cameron H Good, Thomas C Jho. Gene expression and neurochemical characterization of the rostromedial tegmental nucleus (RMTg) in rats and mice. Brain structure & function. vol 224. issue 1. 2019-05-28. PMID:30302539. |
the rostromedial tegmental nucleus (rmtg), also known as the tail of the ventral tegmental area (tvta), is a gabaergic structure identified in 2009 that receives strong inputs from the lateral habenula and other sources, sends dense inhibitory projections to midbrain dopamine (da) neurons, and plays increasingly recognized roles in aversive learning, addiction, and other motivated behaviors. |
2019-05-28 |
2023-08-13 |
mouse |
| Wei Luan, Luke Alexander Hammond, Edmund Cotter, Geoffrey William Osborne, Suzanne Adele Alexander, Virginia Nink, Xiaoying Cui, Darryl Walter Eyle. Developmental Vitamin D (DVD) Deficiency Reduces Nurr1 and TH Expression in Post-mitotic Dopamine Neurons in Rat Mesencephalon. Molecular neurobiology. vol 55. issue 3. 2019-05-23. PMID:28365874. |
developmental vitamin d (dvd) deficiency reduces nurr1 and th expression in post-mitotic dopamine neurons in rat mesencephalon. |
2019-05-23 |
2023-08-13 |
rat |
| Wei Luan, Luke Alexander Hammond, Edmund Cotter, Geoffrey William Osborne, Suzanne Adele Alexander, Virginia Nink, Xiaoying Cui, Darryl Walter Eyle. Developmental Vitamin D (DVD) Deficiency Reduces Nurr1 and TH Expression in Post-mitotic Dopamine Neurons in Rat Mesencephalon. Molecular neurobiology. vol 55. issue 3. 2019-05-23. PMID:28365874. |
it is also unclear if any particular subset of developing dopamine neurons in the mesencephalon is selectively affected. |
2019-05-23 |
2023-08-13 |
rat |
| Wei Luan, Luke Alexander Hammond, Edmund Cotter, Geoffrey William Osborne, Suzanne Adele Alexander, Virginia Nink, Xiaoying Cui, Darryl Walter Eyle. Developmental Vitamin D (DVD) Deficiency Reduces Nurr1 and TH Expression in Post-mitotic Dopamine Neurons in Rat Mesencephalon. Molecular neurobiology. vol 55. issue 3. 2019-05-23. PMID:28365874. |
in this study, we employed state-of-the-art spinning disk confocal microscopy optimized for the imaging of tissue sections and 3d segmentation to assess post-mitotic dopamine cells on a single-cell basis in the rat mesencephalon at embryonic day 15. |
2019-05-23 |
2023-08-13 |
rat |
| Kevin A White, Geoffrey Mulberry, Jonhoi Smith, Manfred Lindau, Bradley A Minch, Kiminobu Sugaya, Brian N Ki. Single-Cell Recording of Vesicle Release From Human Neuroblastoma Cells Using 1024-ch Monolithic CMOS Bioelectronics. IEEE transactions on biomedical circuits and systems. vol 12. issue 6. 2019-05-16. PMID:30059319. |
human neuroblastoma cells, sh-sy5y, are often used as a neuronal model to study parkinson's disease and dopamine release in the substantia nigra, a midbrain region that plays an important role in motor control. |
2019-05-16 |
2023-08-13 |
human |
| William Menegas, Korleki Akiti, Ryunosuke Amo, Naoshige Uchida, Mitsuko Watabe-Uchid. Dopamine neurons projecting to the posterior striatum reinforce avoidance of threatening stimuli. Nature neuroscience. vol 21. issue 10. 2019-05-16. PMID:30177795. |
midbrain dopamine neurons are well known for their role in reward-based reinforcement learning. |
2019-05-16 |
2023-08-13 |
Not clear |
| Luke T Coddington, Joshua T Dudma. The timing of action determines reward prediction signals in identified midbrain dopamine neurons. Nature neuroscience. vol 21. issue 11. 2019-05-16. PMID:30323275. |
the timing of action determines reward prediction signals in identified midbrain dopamine neurons. |
2019-05-16 |
2023-08-13 |
mouse |
| Jean-Francois Poulin, Giuliana Caronia, Caitlyn Hofer, Qiaoling Cui, Brandon Helm, Charu Ramakrishnan, C Savio Chan, Daniel A Dombeck, Karl Deisseroth, Rajeshwar Awatraman. Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches. Nature neuroscience. vol 21. issue 9. 2019-05-15. PMID:30104732. |
midbrain dopamine (da) neurons have diverse functions that can in part be explained by their heterogeneity. |
2019-05-15 |
2023-08-13 |
Not clear |
| Rui Lin, Ruiyu Wang, Jing Yuan, Qiru Feng, Youtong Zhou, Shaoqun Zeng, Miao Ren, Siqi Jiang, Hong Ni, Can Zhou, Hui Gong, Minmin Lu. Cell-type-specific and projection-specific brain-wide reconstruction of single neurons. Nature methods. vol 15. issue 12. 2019-05-13. PMID:30455464. |
we demonstrated its utility for whole-brain reconstruction of midbrain dopamine neurons and striatum-projecting cortical neurons. |
2019-05-13 |
2023-08-13 |
Not clear |
| Benjamin T Saunders, Jocelyn M Richard, Elyssa B Margolis, Patricia H Jana. Dopamine neurons create Pavlovian conditioned stimuli with circuit-defined motivational properties. Nature neuroscience. vol 21. issue 8. 2019-05-10. PMID:30038277. |
we tested the fundamental role of midbrain dopamine neurons in conferring predictive and motivational properties to cues, independent of external rewards. |
2019-05-10 |
2023-08-13 |
Not clear |
| Alessandro Pristerà, Craig Blomeley, Emanuel Lopes, Sarah Threlfell, Elisa Merlini, Denis Burdakov, Stephanie Cragg, François Guillemot, Siew-Lan An. Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 9. 2019-05-08. PMID:30808767. |
midbrain dopamine neurons, which can be regulated by neuropeptides and hormones, play a fundamental role in controlling cognitive processes, reward mechanisms, and motor functions. |
2019-05-08 |
2023-08-13 |
mouse |
| Alessandro Pristerà, Craig Blomeley, Emanuel Lopes, Sarah Threlfell, Elisa Merlini, Denis Burdakov, Stephanie Cragg, François Guillemot, Siew-Lan An. Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 9. 2019-05-08. PMID:30808767. |
we discovered that dopamine neurons secrete igf-1 from the cell bodies following depolarization, and that igf-1 controls release of dopamine in the ventral midbrain. |
2019-05-08 |
2023-08-13 |
mouse |
| Jae-Jin Song, Sang-Min Oh, Oh-Chan Kwon, Noviana Wulansari, Hyun-Seob Lee, Mi-Yoon Chang, Eunsoo Lee, Woong Sun, Sang-Eun Lee, Sunghoe Chang, Heeyoung An, C Justin Lee, Sang-Hun Le. Cografting astrocytes improves cell therapeutic outcomes in a Parkinson's disease model. The Journal of clinical investigation. vol 128. issue 1. 2019-05-07. PMID:29227284. |
in this study, we examined whether astrocytic function could be utilized to overcome the current limitations of cell-based therapies in a murine model of parkinson's disease (pd) that is characterized by dopamine (da) neuron degeneration in the midbrain. |
2019-05-07 |
2023-08-13 |
rat |