| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paul Vezin. Sensitization of midbrain dopamine neuron reactivity and the self-administration of psychomotor stimulant drugs. Neuroscience and biobehavioral reviews. vol 27. issue 8. 2004-04-19. PMID:15019432. |
these results indicate a direct relationship between the sensitization of midbrain dopamine neuron reactivity and the excessive pursuit and self-administration of psychostimulant drugs. |
2004-04-19 |
2023-08-12 |
Not clear |
| Jae-Won Shim, Hyun-Chul Koh, Mi-Yoon Chang, Eun Roh, Cha-Yong Choi, Young J Oh, Hyeon Son, Yong-Sung Lee, Lorenz Studer, Sang-Hun Le. Enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing Bcl-XL. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 4. 2004-04-12. PMID:14749429. |
enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing bcl-xl. |
2004-04-12 |
2023-08-12 |
mouse |
| Jae-Won Shim, Hyun-Chul Koh, Mi-Yoon Chang, Eun Roh, Cha-Yong Choi, Young J Oh, Hyeon Son, Yong-Sung Lee, Lorenz Studer, Sang-Hun Le. Enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing Bcl-XL. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 4. 2004-04-12. PMID:14749429. |
in vitro differentiation of bcl-xl overexpressing es (bcl-es) cells resulted in higher expression of genes related to midbrain dopamine (da) neuron development and increased the number of es-derived neurons expressing midbrain da markers compared with differentiation of wild-type es cells. |
2004-04-12 |
2023-08-12 |
mouse |
| Nao Chuhma, Hui Zhang, Justine Masson, Xiaoxi Zhuang, David Sulzer, René Hen, Stephen Raypor. Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 4. 2004-04-12. PMID:14749442. |
a resolution of this paradox may be that midbrain dopamine neurons exert fast excitatory actions. |
2004-04-12 |
2023-08-12 |
mouse |
| Reiko Kawagoe, Yoriko Takikawa, Okihide Hikosak. Reward-predicting activity of dopamine and caudate neurons--a possible mechanism of motivational control of saccadic eye movement. Journal of neurophysiology. vol 91. issue 2. 2004-03-31. PMID:14523067. |
to study how motivational signals modulate motor signals in the basal ganglia, we examined activity of midbrain dopamine (da) neurons and caudate (cd) projection neurons while monkeys were performing a one-direction-rewarded version (1dr) of memory-guided saccade task. |
2004-03-31 |
2023-08-12 |
monkey |
| Elisa Mengual, Virginia M Picke. Regional and subcellular compartmentation of the dopamine transporter and tyrosine hydroxylase in the rat ventral pallidum. The Journal of comparative neurology. vol 468. issue 3. 2004-03-26. PMID:14681933. |
the vp catecholaminergic innervation is derived from midbrain dopaminergic neurons that differ in expression levels of the dopamine transporter (dat) and from brainstem noradrenergic neurons without dat. |
2004-03-26 |
2023-08-12 |
rat |
| Byron C Jones, Cheryl L Reed, Robert Hitzemann, Jason A Wiesinger, Kristin A McCarthy, James P Buwen, John L Bear. Quantitative genetic analysis of ventral midbrain and liver iron in BXD recombinant inbred mice. Nutritional neuroscience. vol 6. issue 6. 2004-03-05. PMID:14744041. |
genetic correlations between ventral midbrain iron and published dopamine functional indices were significant, suggesting a link between ventral midbrain iron status and central dopamine neurobiology. |
2004-03-05 |
2023-08-12 |
mouse |
| Byron C Jones, Cheryl L Reed, Robert Hitzemann, Jason A Wiesinger, Kristin A McCarthy, James P Buwen, John L Bear. Quantitative genetic analysis of ventral midbrain and liver iron in BXD recombinant inbred mice. Nutritional neuroscience. vol 6. issue 6. 2004-03-05. PMID:14744041. |
this work shows the value of quantitative genetic analysis in the neurobiology of iron and in showing the close association between ventral midbrain iron and nigrostriatal/mesolimbic dopamine function. |
2004-03-05 |
2023-08-12 |
mouse |
| Alexander O Komendantov, Olena G Komendantova, Steven W Johnson, Carmen C Canavie. A modeling study suggests complementary roles for GABAA and NMDA receptors and the SK channel in regulating the firing pattern in midbrain dopamine neurons. Journal of neurophysiology. vol 91. issue 1. 2004-03-01. PMID:13679411. |
a modeling study suggests complementary roles for gabaa and nmda receptors and the sk channel in regulating the firing pattern in midbrain dopamine neurons. |
2004-03-01 |
2023-08-12 |
Not clear |
| Santiago Canals, Maria José Casarejos, Sonsoles de Bernardo, Rosa Maria Solano, Maria Angeles Men. Selective and persistent activation of extracellular signal-regulated protein kinase by nitric oxide in glial cells induces neuronal degeneration in glutathione-depleted midbrain cultures. Molecular and cellular neurosciences. vol 24. issue 4. 2004-02-27. PMID:14697665. |
intracellular glutathione (gsh) levels determine whether nitric oxide (no) is neurotrophic for dopamine neurons or triggers a cell death cascade in primary midbrain cultures. |
2004-02-27 |
2023-08-12 |
Not clear |
| Anselme L Perrier, Lorenz Stude. Making and repairing the mammalian brain--in vitro production of dopaminergic neurons. Seminars in cell & developmental biology. vol 14. issue 3. 2004-02-26. PMID:12948353. |
midbrain dopamine (da) neurons play an essential role in modulating motor control, and their degeneration is the hallmark feature of parkinson's disease (pd). |
2004-02-26 |
2023-08-12 |
Not clear |
| Hui-Ling Chen, Pamela J Lein, Jia-Yi Wang, Don Gash, Barry J Hoffer, Yung-Hsiao Chian. Expression of bone morphogenetic proteins in the brain during normal aging and in 6-hydroxydopamine-lesioned animals. Brain research. vol 994. issue 1. 2004-02-10. PMID:14642451. |
accordingly, we studied the regional distribution of endogenous bmp ligand proteins, receptors, and antagonists during aging and after lesion of the midbrain dopamine pathways produced by 6-hydroxydopamine (6-ohda). |
2004-02-10 |
2023-08-12 |
Not clear |
| Jonathan D Hommel, Robert M Sears, Dan Georgescu, Diana L Simmons, Ralph J DiLeon. Local gene knockdown in the brain using viral-mediated RNA interference. Nature medicine. vol 9. issue 12. 2004-02-05. PMID:14634645. |
here we use viral-mediated rna interference (rnai) to generate a specific knockdown of th, the gene encoding the dopamine synthesis enzyme tyrosine hydroxylase, within midbrain neurons of adult mice. |
2004-02-05 |
2023-08-12 |
mouse |
| Minoru Narita, Masahiro Shibasaki, Keisuke Mizuo, Tsutomu Suzuk. Changes in G-protein activity mediated through the stimulation of dopamine and GABA(B) receptors in the mesolimbic dopaminergic system of morphine-sensitized mice. Addiction biology. vol 8. issue 3. 2004-01-29. PMID:13129834. |
intermittent morphine treatment results in the upregulation of dopamine receptor-regulated g-protein activation in the mouse limbic forebrain, whereas this treatment causes the downregulation of gaba(b) receptor function to activate g-protein in the mouse lower midbrain. |
2004-01-29 |
2023-08-12 |
mouse |
| R Ramakrishnan, M Y Nazer, N Suthanthirarajan, A Namasivaya. An experimental analysis of the catecholamines in hyperglycemia and acidosis induced rat brain. International journal of immunopathology and pharmacology. vol 16. issue 3. 2004-01-29. PMID:14611726. |
in the present study, hyperglycemia maintained by daily external administration of glucose for thirty days showed increased level of dopamine in striatum and hippocampus, elevation of norepinephrine in hippocampus, and increased level of epinephrine in hypothalamus, midbrain and pons medulla. |
2004-01-29 |
2023-08-12 |
human |
| R Ramakrishnan, M Y Nazer, N Suthanthirarajan, A Namasivaya. An experimental analysis of the catecholamines in hyperglycemia and acidosis induced rat brain. International journal of immunopathology and pharmacology. vol 16. issue 3. 2004-01-29. PMID:14611726. |
the ammonium chloride induced acidosis demonstrated significant elevation of dopamine in midbrain and significant increase of norepinephrine in hypothalamus and midbrain, and increased level of epinephrine in hypothalamus, pons medulla and cerebral cortex. |
2004-01-29 |
2023-08-12 |
human |
| Barbara K Lipska, Daniel N Lerman, Zin Z Khaing, Daniel R Weinberge. The neonatal ventral hippocampal lesion model of schizophrenia: effects on dopamine and GABA mRNA markers in the rat midbrain. The European journal of neuroscience. vol 18. issue 11. 2004-01-29. PMID:14656305. |
the neonatal ventral hippocampal lesion model of schizophrenia: effects on dopamine and gaba mrna markers in the rat midbrain. |
2004-01-29 |
2023-08-12 |
human |
| Barbara K Lipska, Daniel N Lerman, Zin Z Khaing, Daniel R Weinberge. The neonatal ventral hippocampal lesion model of schizophrenia: effects on dopamine and GABA mRNA markers in the rat midbrain. The European journal of neuroscience. vol 18. issue 11. 2004-01-29. PMID:14656305. |
we used in situ hybridization histochemistry to assess expression of mrnas for dopamine transporter (dat), tyrosine hydroxylase (th) and glutamate decarboxylase-67 (gad67) in the midbrain of adult rats with neonatal and adult ibotenic acid lesions of the ventral hippocampus. |
2004-01-29 |
2023-08-12 |
human |
| E Paolucci, N Berretta, A Tozzi, G Bernardi, N B Mercur. Depression of mGluR-mediated IPSCs by 5-HT in dopamine neurons of the rat substantia nigra pars compacta. The European journal of neuroscience. vol 18. issue 10. 2004-01-26. PMID:14656323. |
in the present report we examined the role of 5-ht in the modulation of the metabotropic glutamate receptor-mediated inhibitory postsynaptic current (mglur-ipsc) in midbrain dopamine neurons, and we found a reversible depression of this synaptic response at concentrations of 5-ht ranging from 100 nm to 30 microm (ec50 1.06 microm). |
2004-01-26 |
2023-08-12 |
rat |
| E Paolucci, N Berretta, A Tozzi, G Bernardi, N B Mercur. Depression of mGluR-mediated IPSCs by 5-HT in dopamine neurons of the rat substantia nigra pars compacta. The European journal of neuroscience. vol 18. issue 10. 2004-01-26. PMID:14656323. |
our results demonstrate a powerful inhibition of the mglur-ipsc by 5-ht in midbrain dopamine neurons, most probably through stimulation of 5-ht2a and 5-ht4 receptors. |
2004-01-26 |
2023-08-12 |
rat |