| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Schilström, M Mameli-Engvall, N Rawal, P Grillner, K Jardemark, T H Svensso. Nitric oxide is involved in nicotine-induced burst firing of rat ventral tegmental area dopamine neurons. Neuroscience. vol 125. issue 4. 2004-08-02. PMID:15120855. |
in the present study, using single cell recordings in vivo and intracellular recordings in vitro from midbrain slices, the role of n-methyl-d-aspartate (nmda) receptor signaling on firing activity in ventral tegmental area dopamine neurons elicited by nicotine was investigated in the rat. |
2004-08-02 |
2023-08-12 |
rat |
| Michael J Beckstead, David K Grandy, Kevin Wickman, John T William. Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons. Neuron. vol 42. issue 6. 2004-08-02. PMID:15207238. |
vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons. |
2004-08-02 |
2023-08-12 |
mouse |
| Michael J Beckstead, David K Grandy, Kevin Wickman, John T William. Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons. Neuron. vol 42. issue 6. 2004-08-02. PMID:15207238. |
synchronous activation of dopamine neurons, for instance upon presentation of an unexpected rewarding stimulus, results in the release of dopamine from both terminals in projection areas and somatodendritic sites within the ventral midbrain. |
2004-08-02 |
2023-08-12 |
mouse |
| Michael J Beckstead, David K Grandy, Kevin Wickman, John T William. Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons. Neuron. vol 42. issue 6. 2004-08-02. PMID:15207238. |
this report describes an inhibitory postsynaptic current (ipsc) that was elicited by dopamine in slices from mouse midbrain. |
2004-08-02 |
2023-08-12 |
mouse |
| Masami Ishido, Yoshinori Masuo, Manabu Kunimoto, Syuichi Oka, Masatoshi Morit. Bisphenol A causes hyperactivity in the rat concomitantly with impairment of tyrosine hydroxylase immunoreactivity. Journal of neuroscience research. vol 76. issue 3. 2004-07-29. PMID:15079872. |
based on dna macroarray analyses of the midbrain, bisphenol a decreased by more than twofold gene expression levels of the dopamine d4 receptor at 4 weeks of age and the dopamine transporter at 8 weeks of age. |
2004-07-29 |
2023-08-12 |
rat |
| Marten P Smidt, Simone M Smits, J Peter H Burbac. Molecular mechanisms underlying midbrain dopamine neuron development and function. European journal of pharmacology. vol 480. issue 1-3. 2004-07-22. PMID:14623352. |
molecular mechanisms underlying midbrain dopamine neuron development and function. |
2004-07-22 |
2023-08-12 |
Not clear |
| Leu-Fen H Lin, Lee L Rubin, Mei X. A non-peptidyl neurotrophic small molecule for midbrain dopaminergic neurons. Journal of neurochemistry. vol 89. issue 6. 2004-07-22. PMID:15189341. |
in embryonic midbrain cultures, cur-162590 increased dopamine uptake and the number of dopaminergic neurons without altering the number of total neurons or astroglia or the uptake of gaba or serotonin. |
2004-07-22 |
2023-08-12 |
Not clear |
| Margaret E Hamilton, Arthur S Freema. Diet and chronic haloperidol effects on rat midbrain dopamine neurons. Synapse (New York, N.Y.). vol 53. issue 1. 2004-07-16. PMID:15150734. |
diet and chronic haloperidol effects on rat midbrain dopamine neurons. |
2004-07-16 |
2023-08-12 |
rat |
| Carlos A Paladini, Jennifer M Mitchell, John T Williams, Gregory P Mar. Cocaine self-administration selectively decreases noradrenergic regulation of metabotropic glutamate receptor-mediated inhibition in dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 22. 2004-07-09. PMID:15175391. |
the present study measured short-term (3 d) and long-term (14 d) access to cocaine, by self-administration or passive exposure, and the regulation of metabotropic glutamate receptor (mglur)-mediated inhibition of dopamine cells in rat midbrain slices. |
2004-07-09 |
2023-08-12 |
rat |
| Shupeng Li, Kun Yang Kim, Jong Hun Kim, Jin Hoi Kim, Moon Seok Park, Jong Yoon Bahk, Myeong Ok Ki. Chronic nicotine and smoking treatment increases dopamine transporter mRNA expression in the rat midbrain. Neuroscience letters. vol 363. issue 1. 2004-07-06. PMID:15157990. |
chronic nicotine and smoking treatment increases dopamine transporter mrna expression in the rat midbrain. |
2004-07-06 |
2023-08-12 |
rat |
| Fumie Yasumoto, Takayuki Negishi, Yoshiyuki Ishii, Shigeru Kyuwa, Yoichiro Kuroda, Yasuhiro Yoshikaw. Endogenous dopamine maintains synchronous oscillation of intracellular calcium in primary cultured-mouse midbrain neurons. Cellular and molecular neurobiology. vol 24. issue 1. 2004-06-28. PMID:15049510. |
endogenous dopamine maintains synchronous oscillation of intracellular calcium in primary cultured-mouse midbrain neurons. |
2004-06-28 |
2023-08-12 |
Not clear |
| Hannu Sariola, Mart Saarm. Novel functions and signalling pathways for GDNF. Journal of cell science. vol 116. issue Pt 19. 2004-06-24. PMID:12953054. |
gdnf and related ligands, neurturin (nrtn), artemin (artn) and persephin (pspn), maintain several neuronal populations in the central nervous systems, including midbrain dopamine neurons and motoneurons. |
2004-06-24 |
2023-08-12 |
Not clear |
| Thomas P Blackburn, Yoshio Minabe, Derek N Middlemiss, Yukihiko Shirayama, Kenji Hashimoto, Charles R Ashb. Effect of acute and chronic administration of the selective 5-HT2C receptor antagonist SB-243213 on midbrain dopamine neurons in the rat: an in vivo extracellular single cell study. Synapse (New York, N.Y.). vol 46. issue 3. 2004-06-21. PMID:12325040. |
effect of acute and chronic administration of the selective 5-ht2c receptor antagonist sb-243213 on midbrain dopamine neurons in the rat: an in vivo extracellular single cell study. |
2004-06-21 |
2023-08-12 |
rat |
| Marina E Wol. LTP may trigger addiction. Molecular interventions. vol 3. issue 5. 2004-06-18. PMID:14993438. |
recently, encouraging observations were made whereby stressful conditions and differing classes of drugs of abuse were found to impinge upon the same excitatory synapses on dopamine neurons in the midbrain. |
2004-06-18 |
2023-08-12 |
Not clear |
| Roland G W Staal, Eugene V Mosharov, David Sulze. Dopamine neurons release transmitter via a flickering fusion pore. Nature neuroscience. vol 7. issue 4. 2004-06-14. PMID:14990933. |
we measured dopamine release from small synaptic vesicles of rat cultured ventral midbrain neurons using carbon fiber amperometry. |
2004-06-14 |
2023-08-12 |
rat |
| M Hanke, L M Farkas, M Jakob, R Ries, J Pohl, A M Sulliva. Heparin-binding epidermal growth factor-like growth factor: a component in chromaffin granules which promotes the survival of nigrostriatal dopaminergic neurones in vitro and in vivo. Neuroscience. vol 124. issue 4. 2004-06-08. PMID:15026116. |
intracerebral administration of this protein at the same time as a 6-hydroxydopamine lesion of the medial forebrain bundle was found to spare dopamine levels in the striatum and tyrosine hydroxylase-immunopositive neurones in the midbrain. |
2004-06-08 |
2023-08-12 |
human |
| Marie E Legare, William H Hannema. Genetic, biochemical, and characterization of neurological mutant 3, a new mouse model for Parkinson's disease. Genetics and molecular research : GMR. vol 2. issue 3. 2004-06-07. PMID:14966677. |
however, there was a significant decrease of 15-20% in the levels of dopamine, and its principal metabolite, 3,4-dihydroxyphenylacetic acid, in the midbrain of affected mice. |
2004-06-07 |
2023-08-12 |
mouse |
| J E Olijslagers, T R Werkman, A C McCreary, R Siarey, C G Kruse, W J Wadma. 5-HT2 receptors differentially modulate dopamine-mediated auto-inhibition in A9 and A10 midbrain areas of the rat. Neuropharmacology. vol 46. issue 4. 2004-05-28. PMID:14975674. |
5-ht (20 microm) enhanced dopamine (da) d2-like receptor mediated reduction of the firing rate of da neurons in the substantia nigra pars compacta (a9) and ventral tegmental area (a10) in a rat midbrain slice preparation. |
2004-05-28 |
2023-08-12 |
rat |
| Chang-Lin Liang, Omar Nelson, Umar Yazdani, Parichehr Pasbakhsh, Dwight C Germa. Inverse relationship between the contents of neuromelanin pigment and the vesicular monoamine transporter-2: human midbrain dopamine neurons. The Journal of comparative neurology. vol 473. issue 1. 2004-05-24. PMID:15067721. |
inverse relationship between the contents of neuromelanin pigment and the vesicular monoamine transporter-2: human midbrain dopamine neurons. |
2004-05-24 |
2023-08-12 |
human |
| Chang-Lin Liang, Omar Nelson, Umar Yazdani, Parichehr Pasbakhsh, Dwight C Germa. Inverse relationship between the contents of neuromelanin pigment and the vesicular monoamine transporter-2: human midbrain dopamine neurons. The Journal of comparative neurology. vol 473. issue 1. 2004-05-24. PMID:15067721. |
these data support the hypothesis that midbrain dopaminergic neurons that synthesize greater amounts of dopamine have more vesicular storage capacity for action potential-induced release of transmitter and that the ventral sn neurons accumulate the most neuromelanin pigment, in part because they have the least vmat2 protein. |
2004-05-24 |
2023-08-12 |
human |